Transcatheter aortic valve replacement: an update.

Abstract:

:Aortic stenosis affects many people worldwide with a significant impact on morbidity and mortality with uncorrected, symptomatic aortic valve stenosis carrying mortality of 50% at one year. Degenerative calcific pathology, the most common cause of aortic stenosis, increases in prevalence with age; estimated prevalence of 5% in individuals over 75 years of age. Despite the malignant prognosis without valve replacement, many patients are not offered surgery due to advanced age and co-existing medical conditions; reported to be a third of symptomatic patients. In the last several years, transcatheter aortic valve replacement has emerged as an alternative treatment in patients with high or prohibitive open surgical risk. The PARTNER cohort B data, employing the Sapien valve, demonstrated a 20% absolute mortality benefit at one year compared with medical therapy. In this review, we provide an update of this technology and discuss patient selection, procedural planning, complications, and look toward the future of transcatheter heart valves in the treatment of aortic stenosis.

journal_name

Curr Cardiol Rep

authors

Halim SA,Kiefer TL,Hughes GC,Hurwitz LM,Harrison JK

doi

10.1007/s11886-013-0367-1

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

367

issue

6

eissn

1523-3782

issn

1534-3170

journal_volume

15

pub_type

杂志文章,评审
  • Cardiovascular Risk Assessment in Patients with Hypertriglyceridemia.

    abstract:PURPOSE OF REVIEW:Assessing the cardiovascular risk associated with hypertriglyceridemia can be challenging due to frequent confounding conditions such as hypertension, diabetes mellitus, and hyperlipidemia. We sought to quantify this risk by examining several meta-analyses as well as subgroup analyses of previously pu...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-018-1013-8

    authors: Evans MC,Stalam T,Miller M

    更新日期:2018-07-10 00:00:00

  • Spontaneous Coronary Artery Dissection.

    abstract::Spontaneous coronary artery dissection is an important etiology of nonatherosclerotic acute coronary syndrome, myocardial infarction, and sudden death. Innovations in the catheterization laboratory including optical coherence tomography and intravascular ultrasound have enhanced the ability to visualize intimal disrup...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-016-0737-6

    authors: Tweet MS,Gulati R,Hayes SN

    更新日期:2016-07-01 00:00:00

  • What niche will newer class III antiarrhythmic drugs occupy?

    abstract::The decline in the use of sodium channel blockers has led to an expanding use of b-blockers and complex class III agents such as sotalol and amiodarone for controlling cardiac arrhythmias. Success with these agents in the context of their side effects has spurred the development of compounds with simpler ion channel-b...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-001-0086-x

    authors: Singh BN,Sarma JS

    更新日期:2001-07-01 00:00:00

  • Advances in axial imaging of peripheral vascular disease.

    abstract::Peripheral artery disease (PAD) has become increasingly common in the US patient population and can be a highly symptomatic and significant source of morbidity. When PAD is suspected, the first-line screening study that is obtained is typically a noninvasive evaluation that includes the ankle brachial index (ABI). Fol...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-015-0644-2

    authors: Meyersohn NM,Walker TG,Oliveira GR

    更新日期:2015-10-01 00:00:00

  • Sudden cardiac death without structural heart disease: update on the long QT and Brugada syndromes.

    abstract::The long QT syndrome (LQTS) and the Brugada syndrome (BrS) are the most common genetic causes of malignant ventricular arrhythmias and sudden cardiac death in young patients with normal cardiac morphology. To date, more than 250 different mutations in seven genes have been identified as causing LQTS, whereas the only ...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-005-0088-1

    authors: Goldenberg I,Moss AJ,Zareba W

    更新日期:2005-09-01 00:00:00

  • Prognostic Biomarkers in Acute Coronary Syndromes: Risk Stratification Beyond Cardiac Troponins.

    abstract:PURPOSE OF REVIEW:Cardiac troponin (cTn) plays an essential role for assessment of outcome in acute coronary syndrome (ACS). However, the prognostic value of cTn is not absolute. In this mini-review, we summarize the evidence on the utility of established biomarkers of left-ventricular dysfunction, hemodynamic stress, ...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-017-0840-3

    authors: Eggers KM,Lindahl B

    更新日期:2017-04-01 00:00:00

  • Variant Angina and Aborted Sudden Cardiac Death.

    abstract:PURPOSE OF REVIEW:Variant angina, which is characterized by recurrent chest pain and transient ECG changes along with angiographic evidence of coronary artery spasm, generally has a favorable prognosis. However, episodes of ischemia caused by vasospasm may lead to potentially life-threatening ventricular arrhythmias an...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-018-0963-1

    authors: Kundu A,Vaze A,Sardar P,Nagy A,Aronow WS,Botkin NF

    更新日期:2018-03-08 00:00:00

  • Management of combined severe carotid and coronary artery disease.

    abstract::Patients with severe carotid and coronary disease-especially if they require coronary artery bypass grafting (CABG)-are at high risk of cardiac events and stroke. Carotid revascularization should be considered for patients with symptomatic carotid disease and bilateral severe asymptomatic carotid stenosis. In patients...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-012-0246-1

    authors: Roffi M,Ribichini F,Castriota F,Cremonesi A

    更新日期:2012-04-01 00:00:00

  • Diastolic function in hypertension.

    abstract::Diastolic dysfunction in patients with hypertension may present as asymptomatic findings on noninvasive testing, or as fulminant pulmonary edema, despite normal left ventricular systolic function. Up to 40% of hypertensive patients presenting with clinical signs of congestive heart failure have normal systolic left ve...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-001-0071-4

    authors: Phillips RA,Diamond JA

    更新日期:2001-11-01 00:00:00

  • Management of Lipid Abnormalities in Patients with Diabetes.

    abstract:PURPOSE OF REVIEW:To describe lipid abnormalities in diabetes, when they occur and the evidence base for lipid management with established and new drugs to prevent diabetes complications. We also discuss how to manage statin intolerance. RECENT FINDINGS:Statins remain first-line therapy in patients with diabetes, thou...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-019-1246-1

    authors: Sillars A,Sattar N

    更新日期:2019-11-22 00:00:00

  • Imaging cardiac neuronal function and dysfunction.

    abstract::In recent years, the importance of alterations of cardiac autonomic nerve function in the pathophysiology of heart diseases including heart failure, arrhythmia, ische-mic heart disease, and diabetes has been increasingly recognized. Several radiolabeled compounds have been synthesized for noninvasive imaging, includin...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-006-0024-z

    authors: Higuchi T,Schwaiger M

    更新日期:2006-03-01 00:00:00

  • New clinical trials in acute and recurrent pericarditis.

    abstract::Clinical trials in the last decade have improved the quality of evidence to support preventive medical strategies to reduce the risk of recurrences after pericarditis. There are essentially three main strategies: (1) to use full anti-inflammatory doses for the treatment of each attack of pericarditis till symptoms res...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-015-0575-y

    authors: Imazio M

    更新日期:2015-01-01 00:00:00

  • Radial Versus Femoral Access for Acute Coronary Syndromes.

    abstract::The feasibility and safety of transradial coronary intervention was demonstrated soon after the description of the transfemoral approach, despite which the use of the femoral artery still dominates in acute coronary syndrome intervention. The advantages of using the radial artery are virtual elimination of access site...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-015-0676-7

    authors: Routledge H,Sastry S

    更新日期:2015-12-01 00:00:00

  • Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Treatment of Unprotected Left Main Stenosis.

    abstract:PURPOSE OF REVIEW:This article reviews the latest data on unprotected left main (ULM) percutaneous coronary intervention (PCI) versus coronary artery bypass graft (CABG) surgery, with a focus on the NOBLE and EXCEL trials. RECENT FINDINGS:In EXCEL trial, the primary endpoint at 3 years was 15.4% in the PCI group and 1...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-019-1113-0

    authors: Taha Y,Patel RAG,Bagai J,Sachdeva R,Kumar G,Prasad A,Nathan S,Paul TK

    更新日期:2019-03-18 00:00:00

  • Utilizing risk scores in determining the optimal revascularization strategy for complex coronary artery disease.

    abstract::Percutaneous coronary intervention (PCI) of multivessel and/or left main stem disease have been shown to be potentially legitimate revascularization alternatives in appropriately selected patients. Risk stratification is an important component in guiding patients to identify the most appropriate revascularization moda...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-011-0202-5

    authors: Farooq V,Brugaletta S,Serruys PW

    更新日期:2011-10-01 00:00:00

  • Safety and efficacy of nesiritide for acute decompensated heart failure: recent literature and upcoming trials.

    abstract::Congestive heart failure is increasing in prevalence in the United States, and associated morbidity and mortality remain high. Aggressive treatment of decompensated heart failure is associated with improved outcomes; however, therapies must be tailored to the presenting characteristics of each patient and most carry a...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/BF02938348

    authors: Hiestand B,Abraham WT

    更新日期:2007-05-01 00:00:00

  • Coronary Artery Anomalies: When You Need to Worry.

    abstract:PURPOSE OF REVIEW:There is a broad spectrum of coronary artery anomalies that cardiologists may encounter either incidentally or during evaluation for cardiac symptoms. These anomalies include anomalous coronary arteries arising from the opposite sinus of Valsalva (ACAOS), coronary fistulae, and coronary artery aneurys...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-017-0854-x

    authors: Kochar A,Kiefer T

    更新日期:2017-05-01 00:00:00

  • Imaging, Health Record, and Artificial Intelligence: Hype or Hope?

    abstract:PURPOSE OF REVIEW:The review is focused on "digital health", which means advanced analytics based on multi-modal data. The "Health Care Internet of Things", which uses sensors, apps, and remote monitoring could provide continuous clinical information in the cloud that enables clinicians to access the information they n...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-018-0990-y

    authors: Mazzanti M,Shirka E,Gjergo H,Hasimi E

    更新日期:2018-05-10 00:00:00

  • Multimodality imaging for assessment of myocardial viability: nuclear, echocardiography, MR, and CT.

    abstract::The assessment of myocardial viability may be an important component of the evaluation of patients with coronary artery disease and left ventricular dysfunction. The primary goal of viability assessment in such patients is to guide therapeutic decisions by determining which patients would most likely benefit from reva...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-011-0242-x

    authors: Arrighi JA,Dilsizian V

    更新日期:2012-04-01 00:00:00

  • Recent role of imaging in the diagnosis of pericardial disease.

    abstract::Noninvasive cardiac imaging techniques have made a striking impact on the evaluation and management of pericardial disorders. Two-dimensional and Doppler echocardiography are the methods of choice in the evaluation of pericardial effusion and cardiac tamponade. Magnetic resonance imaging, computed tomography, and tran...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-002-0124-3

    authors: Karia DH,Xing YQ,Kuvin JT,Nesser HJ,Pandian NG

    更新日期:2002-01-01 00:00:00

  • Restoring normal sinus rhythm in atrial fibrillation : evidence from pharmacologic therapy and catheter ablation trials.

    abstract::Although clinical evidence indicates that many of the electrophysiologic and functional changes associated with atrial fibrillation (AF) can be reversed by maintaining normal sinus rhythm (NSR), a series of large-scale randomized trials failed to demonstrate that this strategy provides a survival advantage. These stud...

    journal_title:Current cardiology reports

    pub_type: 杂志文章

    doi:10.1007/s11886-006-0078-y

    authors: Zimetbaum P

    更新日期:2006-09-01 00:00:00

  • Percutaneous aortic valve replacement.

    abstract::Aortic valve replacement can produce dramatic benefit in the setting of aortic stenosis. The potential for morbidity and mortality associated with thoracotomy, cardiopulmonary bypass, and aortotomy has fostered a search for alternatives. Early experience with transcatheter endovascular aortic valve implantation demons...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-008-0019-z

    authors: Webb JG

    更新日期:2008-03-01 00:00:00

  • Hypertension in black patients: special issues and considerations.

    abstract::The excess risk of hypertension in black Americans continues to be a major health concern. Although there is considerable information regarding these disease trends, much of the major underpinnings of the etiology of hypertension remain unclear. The excess mortality in blacks due to heart disease, renal failure, and s...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-004-0048-1

    authors: Nesbitt SD

    更新日期:2004-11-01 00:00:00

  • Advances in interventional cardiovascular MRI.

    abstract::Because of its superior soft tissue imaging, MRI has become a valuable diagnostic tool in cardiovascular disease. These strengths make MRI attractive to guide therapeutic catheter-based procedures, both conventional and novel. We review how to configure an interventional MRI suite, how MRI catheter devices differ from...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-006-0014-1

    authors: Raman VK,Lederman RJ

    更新日期:2006-02-01 00:00:00

  • Large-Scale Genomic Biobanks and Cardiovascular Disease.

    abstract:PURPOSE OF REVIEW:Cardiovascular disease is a leading cause of morbidity and mortality worldwide and is the focus of extensive biomedical research. Large genetic consortia combining data from many traditional prospective cohort and ascertained case-control study designs have facilitated the discovery of genetic associa...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-018-0969-8

    authors: Small AM,O'Donnell CJ,Damrauer SM

    更新日期:2018-03-08 00:00:00

  • Inflammatory markers and stroke.

    abstract::Basic and animal research implicate inflammatory mechanisms in the pathogenesis and progression of atherosclerosis, plaque rupture, thrombosis, and stroke. Inflammatory biomarkers, particularly high-sensitivity C-reactive protein and lipoprotein-associated phospholipase A2, have been identified as potential predictors...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-009-0003-2

    authors: Elkind MS

    更新日期:2009-01-01 00:00:00

  • Percutaneous Endovascular Aortic Aneurysm Repair for Abdominal Aortic Aneurysm.

    abstract:PURPOSE OF REVIEW:This review discusses the benefits of a completely percutaneous approach to endovascular aortic aneurysm repair (EVAR), and provides an outline as to how this is performed by a multidisciplinary team of cardiologists and cardiovascular surgeons at a quaternary care community hospital. RECENT FINDINGS...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-018-1023-6

    authors: Huff CM,Silver MJ,Ansel GM

    更新日期:2018-07-26 00:00:00

  • Rationale and Current Evidence for Testing Iron Chelators for Treating Stroke.

    abstract:PURPOSE OF REVIEW:To discuss the mechanisms of iron regulation in the brain and the pathophysiological role of deregulation of iron homeostasis following a stroke, and to review existing evidence supporting the potential role of iron chelators in the treatment of ischemic and hemorrhagic stroke. RECENT FINDINGS:In rec...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-019-1106-z

    authors: Hanafy KA,Gomes JA,Selim M

    更新日期:2019-03-04 00:00:00

  • Genetic Risk Factors for Ischemic and Hemorrhagic Stroke.

    abstract::Understanding the genetic risk factors for stroke is an essential step to decipher the underlying mechanisms, facilitate the identification of novel therapeutic targets, and optimize the design of prevention strategies. A very small proportion of strokes are attributable to monogenic conditions, the vast majority bein...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-016-0804-z

    authors: Chauhan G,Debette S

    更新日期:2016-12-01 00:00:00

  • Noninvasive assessment of coronary artery disease in women: What's next?

    abstract::Significant progress in research has been made in the areas of sex-specific aspects of cardiovascular disease. Despite these advances, coronary artery disease (CAD) is the leading cause of death of women in the Western world. Over the past decade, the focused research on women at risk for ischemic heart disease has he...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-010-0084-y

    authors: Phillips LM,Mieres JH

    更新日期:2010-03-01 00:00:00