Safety and efficacy of nesiritide for acute decompensated heart failure: recent literature and upcoming trials.

abstract：:Aldosterone is known to have multiple adverse cardiovascular effects that are reminiscent of but independent from angiotensin II. These effects include endothelial dysfunction, heightened thrombogenicity, inflammation, and reparative fibrosis, and have been described in experimental and human models of aldosterone exc...

journal_title：Current cardiology reports

authors： Meier DJ,Pitt B,Rajagopalan S

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF THE REVIEW:The aim of this review was to discuss the role of cardiac magnetic resonance (CMR) for the prognostic stratification of cardiomyopathies, highlighting strengths and limitations. RECENT FINDINGS:CMR is considered as a diagnostic pillar in the management of non-ischemic cardiomyopathies. Over the l...

journal_title：Current cardiology reports

authors： Grigoratos C,Todiere G,Barison A,Aquaro GD

更新日期：2020-06-19 00:00:00

abstract：PURPOSE OF REVIEW:Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are commonly used anti-hypertensive medications in a number of clinical settings. They are often used interchangeably, but we pose the provocative question as to whether they should be. We review the literature to evaluate for ...

journal_title：Current cardiology reports

authors： Turner JM,Kodali R

更新日期：2020-07-09 00:00:00

abstract：:Cardiac resynchronization therapy has become part of the treatment strategy for advanced, symptomatic heart failure, but newly published trials show that more patients than previously realized may benefit from this therapy, including those with mild heart failure symptoms. The REVERSE and MADIT-CRT trials showed that ...

journal_title：Current cardiology reports

authors： Reynolds CR,Gold MR

更新日期：2010-09-01 00:00:00

abstract：:Controlled clinical trials, performed in more than 13,000 patients, have consistently shown the beneficial effects of long-term beta-blocker therapy in patients with chronic heart failure. However, it is not clear whether this is a class effect or if it is specific only for some agents. Beneficial effects on the progn...

journal_title：Current cardiology reports

authors： Metra M,Nodari S,Boldi E,Dei Cas L

更新日期：2000-05-01 00:00:00

abstract：:Anticoagulation has proven to be a key component in the management of acute coronary syndromes (ACS). Pharmacological agents with various modes of action are utilized to reduce thrombus development by impairing thrombin formation, platelet activation, and platelet aggregation. The optimal management of these patients ...

journal_title：Current cardiology reports

authors： Burke DA,Warraich HJ,Pinto DS

更新日期：2012-08-01 00:00:00

abstract：:Shared decision-making, central to evidence-based medicine and good patient care, begins and ends with the patient. It is the process by which a clinician and a patient jointly make a health decision after discussing options, potential benefits and harms, and considering the patient's values and preferences. Patient e...

journal_title：Current cardiology reports

authors： Kambhampati S,Ashvetiya T,Stone NJ,Blumenthal RS,Martin SS

更新日期：2016-05-01 00:00:00

abstract：:Hypertension in children and adolescents is becoming a greater problem in the developed world. Although traditionally thought of as usually secondary to renal, vascular, or endocrine causes, primary hypertension is becoming the most common form seen in childhood. This changing epidemiology is related to the recent obe...

journal_title：Current cardiology reports

authors： Samuels J,Bell C,Samuel J,Swinford R

更新日期：2015-12-01 00:00:00

abstract：:Four non-communicable diseases-cardiovascular disease, chronic respiratory disease, diabetes mellitus, and cancer-account for over 60 % of all deaths globally. In recognition of this significant epidemic, the United Nations set forth a target of reducing the four major NCDs by 25 % by 2025. Cardiovascular disease alon...

journal_title：Current cardiology reports

authors： Dugani S,Gaziano TA

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the mechanisms of iron regulation in the brain and the pathophysiological role of deregulation of iron homeostasis following a stroke, and to review existing evidence supporting the potential role of iron chelators in the treatment of ischemic and hemorrhagic stroke. RECENT FINDINGS:In rec...

journal_title：Current cardiology reports

authors： Hanafy KA,Gomes JA,Selim M

更新日期：2019-03-04 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the dynamic relationship between diabetes mellitus (DM) and coronary artery disease (CAD) with respect to different revascularization strategies and how angiographic tools such as the Synergy between PCI with Taxus and Cardiac Surgery (SYNTAX) score can supplement clinical decisi...

journal_title：Current cardiology reports

authors： Kundu A,Sardar P,O'Day K,Chatterjee S,Owan T,Dawn Abbott J

更新日期：2018-03-23 00:00:00

abstract：:The most common cause of acute coronary syndrome (ACS) is rupture of an atherosclerotic lesion containing a large necrotic core and a thin fibrous cap followed by acute luminal thrombosis because the rupture of the thin fibrous cap allows contact of the platelets with the highly thrombogenic necrotic core. Pathologic ...

journal_title：Current cardiology reports

authors： Choi SY,Mintz GS

更新日期：2010-07-01 00:00:00

abstract：:Plasminogen activation potential in the blood is controlled by an equilibrium between plasminogen activators, mainly tissue-type plasminogen activator (t-PA), and inhibitors, mainly plasminogen activator inhibitor (PAI)-1. In cardiovascular practice, imbalance of this fibrinolytic potential is encountered primarily in...

journal_title：Current cardiology reports

authors： Juhan-Vague I,Morange P,Christine Alessi M

更新日期：1999-07-01 00:00:00

abstract：:Aortic stenosis is a common valvular abnormality. Surgical valve replacement is the standard of care for symptomatic patients with severe aortic stenosis and is appropriate for certain asymptomatic patients. Statin therapy may slow progression of the disease. Contrary to conventional wisdom, vasodilator therapy may in...

journal_title：Current cardiology reports

authors： Botkin NF,Aurigemma GP

更新日期：2004-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyze the current state of the art of functional mitral regurgitation (FMR) treatment. RECENT FINDINGS:The first-line treatment of severe FMR consists of guideline medical therapy (GMT) and resynchronization therapy when indicated; the impact of new medical therapies like sacubitril/valsartan ne...

journal_title：Current cardiology reports

authors： Fabris E,De Luca A,Vitrella G,Stolfo D,Masè M,Korcova R,Merlo M,Rakar S,Van't Hof AWJ,Kedhi E,Perkan A,Sinagra G

更新日期：2019-11-16 00:00:00

abstract：:Although advanced heart failure has been considered the main indication for heart transplantation, the increasing number of candidates and shortage of organs for transplantation, with accumulating waiting lists, has originated another look into more conventional surgery, previously considered of prohibitive risk. In f...

journal_title：Current cardiology reports

authors： Ferrão de Oliveira J,Antunes MJ

更新日期：2004-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The present article reviews the pathophysiology of cardiac sympathetic denervation, the principles of positron emission tomography (PET) imaging of the sympathetic innervation of the heart and its potential clinical role, based on current and expected future evidence. RECENT FINDINGS:Imaging of cardi...

journal_title：Current cardiology reports

authors： van der Bijl P,Knuuti J,Delgado V,Bax JJ

更新日期：2020-11-27 00:00:00

abstract：:The rapid growth of medical knowledge during the past few decades has created many potential advances in the therapeutics of chronic disease, and cardiovascular disease has been at the center of this phenomenon. Translation of these advances into everyday care of patients with chronic disease continues to be problemat...

journal_title：Current cardiology reports

authors： Adams KF

更新日期：2001-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This study aims to describe the current state of telestroke clinical applications and policies, in addition to key technical and operational aspects of the telemedicine practice. RECENT FINDINGS:Delivery of telestroke services for neurovascular care expanded from the intravenous alteplase decision an...

journal_title：Current cardiology reports

authors： Dumitrascu OM,Demaerschalk BM

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The development of biventricular repair and conversion pathways for patients with borderline hypoplastic heart disease represents an area of recent inquiry and innovation. This review summarizes emerging techniques and novel treatment algorithms for borderline hypoplastic heart disease with a focus on...

journal_title：Current cardiology reports

authors： Andersen ND,Scherba JC,Turek JW

更新日期：2020-08-08 00:00:00

abstract：:Despite a vast body of research on antithrombotic therapy for patients with cardiac disease, there are few clinical settings where robust evidence of their benefit exists. Patients with heart failure often have vascular disease and atrial fibrillation contributing to their poor prognosis. For patients with heart failu...

journal_title：Current cardiology reports

authors： Cleland JG,Mumtaz S,Cecchini L

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Moderate or severe aortic regurgitation (AR) occurs in 0.5% of the population and typically peaks in the fourth to sixth decade of life. A significant proportion of patients have prohibitive surgical risk and are therefore treated medically with pharmacological management of heart failure and no d...

journal_title：Current cardiology reports

authors： Markham R,Ghodsian M,Sharma R

更新日期：2020-07-28 00:00:00

abstract：:Diabetic patients who present with an acute coronary syndrome (ACS) have a particularly adverse prognosis, largely contributed by increased platelet reactivity and higher burden of disease severity. Diabetic patients with ACS derive a greater benefit from established therapies, particularly platelet-inhibiting therapi...

journal_title：Current cardiology reports

authors： Amin AP,Marso SP

更新日期：2010-07-01 00:00:00

abstract：:A number of neurohormones and cytokines are activated in heart failure and their activity is related to the progression of heart failure. Inhibiting the deleterious effects of the activated sympathetic and the renin-angiotensin-aldosterone systems with b-blockers, angiotensin-converting enzyme inhibitors, and aldoster...

journal_title：Current cardiology reports

authors： Anand IS

更新日期：2004-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To assess current management strategies for advanced heart failure in adults with congenital heart disease, including heart transplantation and mechanical circulatory support. RECENT FINDINGS:Current data demonstrate that adults with CHD generally experience higher short-term mortality after heart tr...

journal_title：Current cardiology reports

authors： Serfas JD,Patel PA,Krasuski RA

更新日期：2018-08-09 00:00:00

abstract：:Heart failure management is complex and costly. Genetic variations that alter drug absorption, metabolism, and receptor-ligand interactions have the potential to modify drug response and safety. Evidence shows that genetic factors interact with numerous heart failure medications, including vasodilators, beta blockers,...

journal_title：Current cardiology reports

authors： Lowes BD,Buttrick PM

更新日期：2008-05-01 00:00:00

abstract：:The article title in the original publication contains a mistake. ...

journal_title：Current cardiology reports

authors： Edelson JB,Genuardi MV,Santangeli P,Birati EY

更新日期：2020-09-08 00:00:00

abstract：:Radiofrequency ablation is a valuable adjunctive therapy to implantable defibrillators in patients with recurrent monomorphic ventricular tachycardia (VT) after myocardial infarction. Episodes of VT are markedly reduced in most patients, and the major complications are less than 5%. Newer approaches allow successful a...

journal_title：Current cardiology reports

authors： Soejima K,Stevenson WG

更新日期：2003-09-01 00:00:00

abstract：:Heart failure is becoming increasingly prevalent, and currently coronary artery disease (CAD) is the primary cause of left ventricular (LV) systolic dysfunction. A potential therapeutic option for patients with severe CAD and LV dysfunction is a strategy of revascularization. In this review, we summarize the available...

journal_title：Current cardiology reports

authors： Ghose T,Thompson RC

更新日期：2006-07-01 00:00:00

abstract：:Atherosclerosis is the proximate cause of arterial thrombosis, leading to acute occlusive cardiovascular syndromes. Thrombosis in atherosclerosis usually results from rupture of the fibrous cap of atherosclerotic plaques with a smaller proportion resulting from superficial endothelial erosion. Ruptured plaques are oft...

journal_title：Current cardiology reports

authors： Shah PK

更新日期：2014-12-01 00:00:00