The need for combination drug therapies in patients with complex dyslipidemia.

abstract：:Cardiac resynchronization therapy (CRT) is a proven treatment for heart failure and requires the implantation of a left ventricular (LV) lead, usually placed in a tributary of the coronary sinus. Encouraged by the fact that approximately 30 % of the patients receiving CRT do not benefit from this therapy, LV endocardi...

journal_title：Current cardiology reports

authors： Bordachar P,Ploux S,Lumens J

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To establish the actual role of CT in the growing field of transcatheter valve interventions (THV). RECENT FINDINGS:The development of empirical CT measurements, which are linked with outcomes. CT is a reliable technique for assessing risk and planning transcatheter valve interventions for mitral and...

journal_title：Current cardiology reports

authors： Godoy M,Mugharbil A,Anastasius M,Leipsic J

更新日期：2019-11-25 00:00:00

abstract：:Gut microbiota has been recently established to have a contributory role in the development of cardiometabolic disorders, such as atherosclerosis, obesity, and type 2 diabetes. Growing interest has focused on the modulation of gut microbiota as a therapeutic strategy in cardiovascular diseases and metabolic disorders....

journal_title：Current cardiology reports

authors： Miele L,Giorgio V,Alberelli MA,De Candia E,Gasbarrini A,Grieco A

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac troponin (cTn) plays an essential role for assessment of outcome in acute coronary syndrome (ACS). However, the prognostic value of cTn is not absolute. In this mini-review, we summarize the evidence on the utility of established biomarkers of left-ventricular dysfunction, hemodynamic stress, ...

journal_title：Current cardiology reports

authors： Eggers KM,Lindahl B

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Innovation for transcatheter aortic valve replacement (TAVR) has transformed a medically complex treatment into a standardized procedure. While Edwards SAPIEN and Medtronic CoreValve occupy the market for TAVR in the United States (US), additional valve systems are being developed. The Boston Scientif...

journal_title：Current cardiology reports

authors： Seigerman ME,Nathan A,Anwaruddin S

更新日期：2019-11-25 00:00:00

abstract：:Imaging with radionuclides has historically played an important role in detection of cardiovascular disease as well as in risk stratification and prognostication. With the growth of molecular biology have come new therapeutic interventions and the requirement for new diagnostic imaging approaches. Noninvasive targeted...

journal_title：Current cardiology reports

authors： Dobrucki LW,Sinusas AJ

更新日期：2005-03-01 00:00:00

abstract：:Coronary artery bypass grafting without the aid of cardiopulmonary bypass (CPB) continues to gain popularity as an alternative to standard techniques of revascularization. CPB with cardioplegic arrest is associated with complications that may negate an otherwise technically flawless procedure. Experience has identifie...

journal_title：Current cardiology reports

authors： Dewey TM,Mack MJ

更新日期：1999-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This study aims to describe the current state of telestroke clinical applications and policies, in addition to key technical and operational aspects of the telemedicine practice. RECENT FINDINGS:Delivery of telestroke services for neurovascular care expanded from the intravenous alteplase decision an...

journal_title：Current cardiology reports

authors： Dumitrascu OM,Demaerschalk BM

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this report is to describe the main aspects of sex-related differences in non-ischemic dilated cardiomyopathies (DCM), focusing on chemotherapy-induced heart failure (HF) and investigating the possible therapeutic implications and clinical management applications in the era of personalized ...

journal_title：Current cardiology reports

authors： D'Amario D,Camilli M,Migliaro S,Canonico F,Galli M,Arcudi A,Montone RA,Borovac JA,Crea F,Savarese G

更新日期：2020-08-08 00:00:00

abstract：:Transcatheter aortic valve replacement (TAVR) has become an alternative to surgical intervention for symptomatic or severe aortic valve stenosis in patients with high surgical risk. Successful TAVR requires a multimodality imaging approach for appropriate patient selection and prosthesis sizing. Here, we describe indi...

journal_title：Current cardiology reports

authors： Caruso D,Rosenberg RD,De Cecco CN,Mangold S,Wichmann JL,Varga-Szemes A,Steinberg DH,Laghi A,Schoepf UJ

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine the utility and methods of coronary artery disease (CAD) assessment in patients with new-onset heart failure with reduced ejection fraction (HFrEF) of unclear etiology. Moreover, we sought to review the role and techniques of assessing myocardial viability to guide coronary revascularizatio...

journal_title：Current cardiology reports

authors： Kassab K,Kattoor AJ,Doukky R

更新日期：2020-07-06 00:00:00

abstract：PURPOSE OF REVIEW:The present article reviews the pathophysiology of cardiac sympathetic denervation, the principles of positron emission tomography (PET) imaging of the sympathetic innervation of the heart and its potential clinical role, based on current and expected future evidence. RECENT FINDINGS:Imaging of cardi...

journal_title：Current cardiology reports

authors： van der Bijl P,Knuuti J,Delgado V,Bax JJ

更新日期：2020-11-27 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular disease is a leading cause of morbidity and mortality worldwide and is the focus of extensive biomedical research. Large genetic consortia combining data from many traditional prospective cohort and ascertained case-control study designs have facilitated the discovery of genetic associa...

journal_title：Current cardiology reports

authors： Small AM,O'Donnell CJ,Damrauer SM

更新日期：2018-03-08 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the effects of psychological stress on the physiology of the entire vascular system, from individual cellular components to macrovascular and microvascular responses, and highlights the importance of the vascular system in the context of current limitations in cardiac imaging for...

journal_title：Current cardiology reports

authors： Shah SM,Meadows JL,Burg MM,Pfau S,Soufer R

更新日期：2020-10-09 00:00:00

abstract：PURPOSE OF REVIEW:Congenital heart disease is the most common birth defect and acquired heart disease is the leading cause of death in adults. Understanding the mechanisms that drive cardiomyocyte proliferation and differentiation has the potential to advance the understanding and potentially the treatment of different...

journal_title：Current cardiology reports

authors： Yester JW,Kühn B

更新日期：2017-02-01 00:00:00

abstract：:Angiotensin-converting enzyme (ACE) inhibitors have become the cornerstone of therapy for congestive heart failure (CHF). Because ischemic heart disease is the most common cause of CHF, aspirin is frequently given concomitantly with ACE inhibitors in patients with CHF. Increased bradykinin levels, with the consequent ...

journal_title：Current cardiology reports

authors： Moskowitz R

更新日期：2001-05-01 00:00:00

abstract：:Basic and animal research implicate inflammatory mechanisms in the pathogenesis and progression of atherosclerosis, plaque rupture, thrombosis, and stroke. Inflammatory biomarkers, particularly high-sensitivity C-reactive protein and lipoprotein-associated phospholipase A2, have been identified as potential predictors...

journal_title：Current cardiology reports

authors： Elkind MS

更新日期：2009-01-01 00:00:00

abstract：:Diabetes mellitus (DM) is a metabolic disorder of multiple etiologies that causes long-term damage of various organs including the cardiovascular system. A consistent observation shows that DM amplifies the risk of cardiovascular events by 4- to 6-fold. Since coronary artery disease (CAD) in diabetic patients exhibits...

journal_title：Current cardiology reports

authors： Soran O

更新日期：2013-01-01 00:00:00

abstract：:Thrombolytic therapy aims to achieve rapid and sustained infarct-related artery patency, although this results in a procoagulant state. Heparin has limitations as an antithrombin agent, which has led to clinical investigation of alternative agents. Direct thrombin inhibitors, as adjuncts to thrombolytic therapy, have ...

journal_title：Current cardiology reports

authors： French JK,White HD

更新日期：1999-09-01 00:00:00

abstract：:Significant progress in research has been made in the areas of sex-specific aspects of cardiovascular disease. Despite these advances, coronary artery disease (CAD) is the leading cause of death of women in the Western world. Over the past decade, the focused research on women at risk for ischemic heart disease has he...

journal_title：Current cardiology reports

authors： Phillips LM,Mieres JH

更新日期：2010-03-01 00:00:00

abstract：:Exercise intolerance in patients with chronic heart failure (CHF) shows no correlation to the degree of left ventricular dysfunction. This surprising finding has directed attention to peripheral changes in CHF: reduced endothelium-dependent vasodilation and altered skeletal muscle metabolism. Physical exercise trainin...

journal_title：Current cardiology reports

authors： Hambrecht R,Gielen S,Schuler G

更新日期：1999-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize lifestyle interventions including pharmacological and non-pharmacological methods targeting modifiable risk factors and their impact on the future cardiovascular events in patients who have suffered transient ischemic attack (TIA) and/or ischemic stroke (IS). RECENT FINDINGS:The latest r...

journal_title：Current cardiology reports

authors： Vellipuram AR,Rodriguez G,Rawla P,Maud A,Cruz-Flores S,Khatri R

更新日期：2019-04-22 00:00:00

abstract：:Heart failure is becoming increasingly prevalent, and currently coronary artery disease (CAD) is the primary cause of left ventricular (LV) systolic dysfunction. A potential therapeutic option for patients with severe CAD and LV dysfunction is a strategy of revascularization. In this review, we summarize the available...

journal_title：Current cardiology reports

authors： Ghose T,Thompson RC

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Results from cardiovascular (CV) outcome trials have revealed important insights into the CV safety and efficacy of glucose-lowering agents, including dipeptidyl peptidase-4 inhibitors (DPP-4i) and glucagon-like peptide-1 receptor agonists (GLP-1RA). RECENT FINDINGS:Among patients with T2DM, DPP-4i h...

journal_title：Current cardiology reports

authors： Patel KV,Sarraju A,Neeland IJ,McGuire DK

更新日期：2020-08-08 00:00:00

abstract：PURPOSE OF THE REVIEW:Coronary artery disease is a major cause of mortality and morbidity in the world, and PCI and CABG account for over a million procedures performed annually in the USA. The goal of percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) is to achieve complete revasculariz...

journal_title：Current cardiology reports

authors： Agrawal H,Teleb M,Lahsaei S,Carbajal L,Montanez R,Carrozza JP Jr

更新日期：2018-03-06 00:00:00

abstract：PURPOSE OF REVIEW:Heart failure with preserved ejection fraction (HFpEF) is a relatively new disease entity used in medical terminology; however, both the number of patients and its clinical significance are growing. HFpEF used to be seen as a mild condition; however, the symptoms and quality of life of the patients ar...

journal_title：Current cardiology reports

authors： Adamczak DM,Oduah MT,Kiebalo T,Nartowicz S,Bęben M,Pochylski M,Ciepłucha A,Gwizdała A,Lesiak M,Straburzyńska-Migaj E

更新日期：2020-07-09 00:00:00

abstract：PURPOSE OF REVIEW:Drug-coated balloons (DEB) and drug-eluting stents (DES) emerged as a tool to aid in lowering the rates of neointimal hyperplasia and target lesion restenosis following endovascular peripheral arterial disease (PAD) interventions. RECENT FINDINGS:Although the initial trials comparing these devices wi...

journal_title：Current cardiology reports

authors： Gad MM,Karrthik AK,Mahmoud AA,Mahmoud AN

更新日期：2019-09-07 00:00:00

abstract：PURPOSE OF REVIEW:This review provides an update on rheumatic mitral stenosis. Acute rheumatic fever (RF), the sequela of group A β-hemolytic streptococcal infection, is the major etiology for mitral stenosis (MS). RECENT FINDINGS:While the incidence of acute RF in the Western world had substantially declined over the...

journal_title：Current cardiology reports

authors： Wunderlich NC,Dalvi B,Ho SY,Küx H,Siegel RJ

更新日期：2019-02-28 00:00:00

abstract：PURPOSE OF REVIEW:Assessing the cardiovascular risk associated with hypertriglyceridemia can be challenging due to frequent confounding conditions such as hypertension, diabetes mellitus, and hyperlipidemia. We sought to quantify this risk by examining several meta-analyses as well as subgroup analyses of previously pu...

journal_title：Current cardiology reports

authors： Evans MC,Stalam T,Miller M

更新日期：2018-07-10 00:00:00

abstract：:Synthesized as an antianginal compound 40 years ago, amiodarone has emerged as a uniquely effective antiarrhythmic compound in recent years. It has numerous properties, the most prominent being the ability to lengthen repolarization in the atria and ventricles associated with bradycardia without the significant potent...

journal_title：Current cardiology reports

authors： Singh BN

更新日期：2006-09-01 00:00:00