Abstract：
:Management of severe chronic mitral regurgitation (MR) in severe heart failure is challenging. There are controversies over the efficacy of surgical correction of MR in the presence of severely depressed left ventricular (LV) function. The etiology of MR plays an important role in clinical decision making. In organic MR, surgical correction should be performed even if patients have an LV ejection fraction of less than or equal to 30%. In functional MR, treatment of myocardial damage should be considered as the priority. The long-term mortality benefit of surgical correction of functional MR associated with severe LV dysfunction caused by cardiomyopathy (ischemic or dilated) likely depends on whether myocardial dysfunction can be reversed or improved by treatments (eg, coronary artery revascularization, pharmacologic treatment). Preoperative examination of viable myocardium (ischemic and hibernating myocardium) helps to identify a surgical candidate with ischemic MR associated with ischemic cardiomyopathy. The role of device treatment of MR in heart failure needs further investigation with outcome data.
journal_name
Curr Cardiol Repjournal_title
Current cardiology reportsauthors
Pu Mdoi
10.1007/s11886-006-0038-6subject
Has Abstractpub_date
2006-05-01 00:00:00pages
226-31issue
3eissn
1523-3782issn
1534-3170journal_volume
8pub_type
杂志文章,评审abstract：:The prevalence of atrial fibrillation increases significantly with age, affecting nearly 10 % of adults greater than 80 years of age. Complications from atrial fibrillation, including stroke, also increase with age. Medical therapy includes anticoagulation, ventricular rate control, and if symptoms persist, maintenanc...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-013-0406-y
更新日期：2013-10-01 00:00:00
abstract：:Over the past decade, catheter based treatments of an increasing variety of cardiac diseases have expanded dramatically. These advancements became available through new developments and improvements in available devices, as well as increasing expertise of operators. However, arguably it is the innovation and progress ...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-012-0338-y
更新日期：2013-03-01 00:00:00
abstract：PURPOSE OF REVIEW:This review discusses the benefits of a completely percutaneous approach to endovascular aortic aneurysm repair (EVAR), and provides an outline as to how this is performed by a multidisciplinary team of cardiologists and cardiovascular surgeons at a quaternary care community hospital. RECENT FINDINGS...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-018-1023-6
更新日期：2018-07-26 00:00:00
abstract：:Glycoprotein IIb/IIIa inhibitors and low molecular heparins are important new components of the medical treatment for acute coronary syndromes (ACS). Renal insufficiency is a common comorbid condition and high-risk marker for ACS. The safety and efficacy of these treatments in ACS are dependent on the pharmacokinetics...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-003-0067-3
更新日期：2003-07-01 00:00:00
abstract：:Primary aldosteronism with a prevalence of 8 % of hypertension and 20 % of pharmacologically resistant hypertension is the most common secondary cause of hypertension. Yet, the diagnosis is missed in the vast majority of patients. Current clinical practice guidelines recommend screening for primary aldosteronism in pa...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-016-0774-1
更新日期：2016-10-01 00:00:00
abstract：PURPOSE OF REVIEW:This study aims to describe the current state of telestroke clinical applications and policies, in addition to key technical and operational aspects of the telemedicine practice. RECENT FINDINGS:Delivery of telestroke services for neurovascular care expanded from the intravenous alteplase decision an...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-017-0895-1
更新日期：2017-09-01 00:00:00
abstract：:Patients with pre-diabetes have a tenfold higher risk of developing Type 2 DM and a twofold higher risk of developing coronary heart disease compared to non-diabetics. Interventions targeted at those in an early stage of impaired glucose metabolism can delay or prevent diabetes. Effects of these interventions on cardi...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-015-0562-3
更新日期：2015-03-01 00:00:00
abstract：:Shared decision-making, central to evidence-based medicine and good patient care, begins and ends with the patient. It is the process by which a clinician and a patient jointly make a health decision after discussing options, potential benefits and harms, and considering the patient's values and preferences. Patient e...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-016-0729-6
更新日期：2016-05-01 00:00:00
abstract：:Statins are first line therapy for the prevention of cardiovascular disease (CVD). Only 30 %-70 % of high risk patients will attain standard low-density lipoprotein cholesterol targets. Patients with familial hypercholesterolemia and genetic mixed hyperlipidemias do not meet goals with standard therapy. Patients with ...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-013-0391-1
更新日期：2013-08-01 00:00:00
abstract：:Over the last several decades, significant advances and improvements in care of transplant patients have resulted in markedly improved outcomes. A number of options are available for patients with advanced cardiopulmonary dysfunction requiring transplantation. There is a debate about when isolated heart or isolated lu...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-016-0713-1
更新日期：2016-04-01 00:00:00
abstract：PURPOSE OF REVIEW:To assess current management strategies for advanced heart failure in adults with congenital heart disease, including heart transplantation and mechanical circulatory support. RECENT FINDINGS:Current data demonstrate that adults with CHD generally experience higher short-term mortality after heart tr...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-018-1028-1
更新日期：2018-08-09 00:00:00
abstract：PURPOSE OF REVIEW:The number of pregnancies complicated by valvular heart disease is increasing. This review describes the hemodynamic effects of clinically important valvular abnormalities during pregnancy and reviews current guideline-driven management strategies. RECENT FINDINGS:Valvular heart disease in women of c...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-017-0910-6
更新日期：2017-08-24 00:00:00
abstract：:Cardiac resynchronization therapy has become part of the treatment strategy for advanced, symptomatic heart failure, but newly published trials show that more patients than previously realized may benefit from this therapy, including those with mild heart failure symptoms. The REVERSE and MADIT-CRT trials showed that ...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-010-0125-6
更新日期：2010-09-01 00:00:00
abstract：:This review focuses on the use of bivalirudin as a replacement anticoagulant for heparin in patients undergoing percutaneous coronary intervention, or who are being treated for unstable angina pectoris, ST-elevation, or non-ST-elevation myocardial infarction. Potential advantages of bivalirudin include a lack of depen...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-001-0050-9
更新日期：2001-09-01 00:00:00
abstract：:Aortic stenosis is a common valvular abnormality. Surgical valve replacement is the standard of care for symptomatic patients with severe aortic stenosis and is appropriate for certain asymptomatic patients. Statin therapy may slow progression of the disease. Contrary to conventional wisdom, vasodilator therapy may in...
journal_title：Current cardiology reports
pub_type： 杂志文章
doi：10.1007/s11886-004-0004-0
更新日期：2004-03-01 00:00:00
abstract：:Peripheral artery disease (PAD) has become increasingly common in the US patient population and can be a highly symptomatic and significant source of morbidity. When PAD is suspected, the first-line screening study that is obtained is typically a noninvasive evaluation that includes the ankle brachial index (ABI). Fol...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-015-0644-2
更新日期：2015-10-01 00:00:00
abstract：:Controlled clinical trials, performed in more than 13,000 patients, have consistently shown the beneficial effects of long-term beta-blocker therapy in patients with chronic heart failure. However, it is not clear whether this is a class effect or if it is specific only for some agents. Beneficial effects on the progn...
journal_title：Current cardiology reports
pub_type： 杂志文章
doi：10.1007/s11886-000-0076-4
更新日期：2000-05-01 00:00:00
abstract：:Exercise intolerance in patients with chronic heart failure (CHF) shows no correlation to the degree of left ventricular dysfunction. This surprising finding has directed attention to peripheral changes in CHF: reduced endothelium-dependent vasodilation and altered skeletal muscle metabolism. Physical exercise trainin...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-999-0041-9
更新日期：1999-05-01 00:00:00
abstract：:The impact of cardiac resynchronization therapy (CRT) on atrial fibrillation (AF) burden is poorly characterized. To assess the influence of CRT on AF, we performed a systematic literature search in MEDLINE using the MeSH headings "cardiac resynchronization therapy" or "cardiac pacing, artificial" and "atrial fibrilla...
journal_title：Current cardiology reports
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s11886-012-0330-6
更新日期：2013-02-01 00:00:00
abstract：PURPOSE OF REVIEW:Ebstein's anomaly (EA) is a rare, but complex form of congenital heart disease consisting of a right ventricular myopathy and morphologic tricuspid valve disease leading to a high incidence of right ventricular dysfunction and arrhythmias. This review offers an updated overview of the current understa...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-020-01412-z
更新日期：2020-10-09 00:00:00
abstract：:One of the most highly unexpected reports in recent medical literature was the lack of benefit of estrogen-progestin replacement therapy in cardiovascular disease prevention in postmenopausal women. The ensuing negative view of hormone replacement therapy has now extended to all forms of postmenopausal hormone treatme...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-003-0110-4
更新日期：2003-11-01 00:00:00
abstract：:Atrial fibrillation (AF) is a very common tachyarrhythmia and is becoming increasingly prevalent, while dementia is a neurological condition manifested as loss of memory and cognitive ability. Both these conditions share several common risk factors. It is becoming increasingly evident that AF increases the risk of dem...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-014-0519-y
更新日期：2014-08-01 00:00:00
abstract：PURPOSE OF REVIEW:The development of biventricular repair and conversion pathways for patients with borderline hypoplastic heart disease represents an area of recent inquiry and innovation. This review summarizes emerging techniques and novel treatment algorithms for borderline hypoplastic heart disease with a focus on...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-020-01363-5
更新日期：2020-08-08 00:00:00
abstract：:Understanding the genetic risk factors for stroke is an essential step to decipher the underlying mechanisms, facilitate the identification of novel therapeutic targets, and optimize the design of prevention strategies. A very small proportion of strokes are attributable to monogenic conditions, the vast majority bein...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-016-0804-z
更新日期：2016-12-01 00:00:00
abstract：PURPOSE OF REVIEW:Coronary artery bypass grafting is a preferred strategy for complete coronary revascularization in patients who have multi-vessel coronary artery disease, left ventricular dysfunction, and/or diabetes. Both arterial (internal thoracic artery/radial artery) and venous grafts are utilized to bypass the ...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-019-1112-1
更新日期：2019-03-22 00:00:00
abstract：:Cardiac surgery (CS) with cardiopulmonary bypass (CPB) is currently the most common surgery in the United States. Understanding, avoiding, and preventing postoperative complications, including neurologic deficits following CS, represents a great public and economic benefit for society, especially considering our aging...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-006-0005-2
更新日期：2006-02-01 00:00:00
abstract：:Sodium is an essential nutrient, mostly ingested as salt (sodium chloride). Average sodium intake ranges from 3 to 6 g per day (7.5-15 g/day of salt) in most countries, with regional variations. Increasing levels of sodium intake have a positive association with higher blood pressure. Randomized controlled trials repo...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-014-0529-9
更新日期：2014-01-01 00:00:00
abstract：:Frailty is increasingly recognized in older adults with cardiovascular disease, particularly in those with heart failure (HF). A growing body of evidence has shown that frailty has a negative effect on survival, hospitalizations, disability, and quality of life. Beyond frailty, additional domains captured by a compreh...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-015-0651-3
更新日期：2015-11-01 00:00:00
abstract：PURPOSE OF REVIEW:We provide a concise update on the contemporary management of cardiogenic shock in the setting of acute coronary syndrome (ACS). Early shock recognition, optimal selection and initiation of mechanical circulatory support (MCS), early coronary revascularization, and a team-based, protocol-driven approa...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-019-1102-3
更新日期：2019-03-04 00:00:00
abstract：:Advances in the field of molecular medicine are making gene therapy a viable treatment strategy for the next millennium. Indeed, over the past 10 years, a number of improvements have occurred that have resulted in an increased interest in gene therapy for the treatment of diseases in cardiovascular medicine. Because a...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-000-0023-4
更新日期：2000-01-01 00:00:00
