Abstract:
:Glycoprotein IIb/IIIa inhibitors and low molecular heparins are important new components of the medical treatment for acute coronary syndromes (ACS). Renal insufficiency is a common comorbid condition and high-risk marker for ACS. The safety and efficacy of these treatments in ACS are dependent on the pharmacokinetics of the specific medication. Even though these treatments have been studied in large randomized controlled trials in ACS, there are few prospective data regarding their safety or efficacy in renal insufficiency. Most have been shown to be safe and effective in mild to moderate degrees of renal insufficiency; none have been thoroughly studied in severe renal disease or in patients requiring dialysis therapy. Future prospective trials should include patients with more severe renal insufficiency, as well as combinations of the current recommended therapies.
journal_name
Curr Cardiol Repjournal_title
Current cardiology reportsauthors
Rammohan C,Fintel Ddoi
10.1007/s11886-003-0067-3keywords:
subject
Has Abstractpub_date
2003-07-01 00:00:00pages
303-9issue
4eissn
1523-3782issn
1534-3170journal_volume
5pub_type
杂志文章,评审abstract::As women with congenital heart disease (CHD) approach childbearing age, issues such as pregnancy and contraception need to be addressed. Women with CHD represent a heterogeneous population. While some have simple cardiac lesions and thus have contraceptive risks that are no different from those of the general populati...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-009-0043-7
更新日期:2009-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of the present manuscript is to review the latest advancements of radionuclide molecular imaging in the diagnosis and prognosis of individuals with cardiac amyloidosis. RECENT FINDINGS:99mTechnetium labeled bone tracer scintigraphy had been known to image cardiac amyloidosis, since the 1980s;...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-017-0868-4
更新日期:2017-07-01 00:00:00
abstract::Fifty thousand Americans suffer an intracerebral hemorrhage (ICH) annually, one third of whom die as a result. Poorly controlled hypertension is the most important risk factor for ICH. Over time it results in pathologic changes to small intracranial vessels, leading to their rupture. All stroke patients, including tho...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-002-0029-1
更新日期:2002-03-01 00:00:00
abstract::Deformation imaging by tissue Doppler imaging (TDI) and speckle-tracking echocardiography (STE) are emerging clinical methods. TDI- and STE-derived parameters, such as myocardial strain and strain rate, as well as torsion and twist, provide detailed information about myocardial function and are associated with cardiov...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-015-0568-x
更新日期:2015-03-01 00:00:00
abstract::Systemic embolic complications in patients with cardiomyopathy are associated with significant morbidity and mortality. Despite the lack of prospective, randomized control data, the literature supports the use of left ventricular ejection fraction as an important determinant of the need for systemic anticoagulation th...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-000-0006-5
更新日期:2000-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The development of biventricular repair and conversion pathways for patients with borderline hypoplastic heart disease represents an area of recent inquiry and innovation. This review summarizes emerging techniques and novel treatment algorithms for borderline hypoplastic heart disease with a focus on...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-020-01363-5
更新日期:2020-08-08 00:00:00
abstract:PURPOSE OF REVIEW:To review the clinical evidence on the use of percutaneous coronary intervention (PCI) revascularization options in left main (LM) disease in comparison with coronary artery bypass graft (CABG). Coronary artery disease (CAD) involving the LM is associated with high morbidity and mortality. Though CABG...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-020-1268-8
更新日期:2020-02-08 00:00:00
abstract:PURPOSE OF REVIEW:To examine the utility and methods of coronary artery disease (CAD) assessment in patients with new-onset heart failure with reduced ejection fraction (HFrEF) of unclear etiology. Moreover, we sought to review the role and techniques of assessing myocardial viability to guide coronary revascularizatio...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-020-01304-2
更新日期:2020-07-06 00:00:00
abstract::The burgeoning ranks of patients with heart failure, the limited number of organs available for heart transplant, and technological improvements have made ventricular assist devices (VADs) important therapeutic options for patients with acute and chronic cardiac decompensation. The increased use of VADs is paralleled ...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-010-0102-0
更新日期:2010-05-01 00:00:00
abstract::Intracranial stenosis accounts for 8-10% of all ischemic strokes in North America, a frequency slightly less than that of extracranial carotid stenosis. Among patients presenting with transient ischemic attack or stroke due to intracranial stenosis, the risk of recurrent stroke in the first year after initial symptoms...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-009-0070-4
更新日期:2010-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Interventional cardiology and in particular the field of renal denervation is subject to constant change. This review provides an up to date overview of renal denervation trials and an outlook on what to expect in the future. RECENT FINDINGS:After the sham-controlled SYMPLICITY HTN-3 trial dampened t...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-019-1164-2
更新日期:2019-07-05 00:00:00
abstract::Selective coronary angiography was originally performed through open brachial arteriotomy. Thereafter, the percutaneous Seldinger technique and the use of preformed Judkins-type catheters popularized the femoral approach. More recently, after the first report of successful coronary angiography by the transradial appro...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-009-0054-4
更新日期:2009-09-01 00:00:00
abstract::Internal carotid artery stenosis accounts for about 7-10 % of ischemic strokes. Conventional risk factors such as aging, hypertension, diabetes mellitus, and smoking increase the risk for carotid atherosclerosis. All patients with carotid stenosis should receive aggressive medical therapy. Carotid revascularization wi...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-015-0625-5
更新日期:2015-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Assessing the cardiovascular risk associated with hypertriglyceridemia can be challenging due to frequent confounding conditions such as hypertension, diabetes mellitus, and hyperlipidemia. We sought to quantify this risk by examining several meta-analyses as well as subgroup analyses of previously pu...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-018-1013-8
更新日期:2018-07-10 00:00:00
abstract:PURPOSE OF REVIEW:While the safety and efficacy of percutaneous ASD closure has been established, new data have recently emerged regarding the negative impact of residual iatrogenic ASD (iASD) following left heart structural interventions. Additionally, new devices with potential advantages have recently been studied. ...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-018-0983-x
更新日期:2018-04-17 00:00:00
abstract::Congestive heart failure is increasing in prevalence in the United States, and associated morbidity and mortality remain high. Aggressive treatment of decompensated heart failure is associated with improved outcomes; however, therapies must be tailored to the presenting characteristics of each patient and most carry a...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/BF02938348
更新日期:2007-05-01 00:00:00
abstract:PURPOSE OF REVIEW:To create awareness for the devastating influence of high cholesterol in familial hypercholesterolaemia (FH) on vessel walls. Persons with high LDL-C and a known mutation associated with FH have a 22-fold increase in CVD compared with those with a normal LDL-C and no genetic mutation. If the awareness...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-018-1014-7
更新日期:2018-08-09 00:00:00
abstract::The appropriateness of coronary revascularization for various clinical scenarios has been reviewed formally by several specialty and subspecialty societies resulting in the formulation of scored appropriateness criteria. The goal of the appropriateness criteria is to guide physician decision-making and future research...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-013-0379-x
更新日期:2013-07-01 00:00:00
abstract::The Fontan operation has been nothing short of revolutionary in its influence on the modern management of patients born with functionally univentricular hearts. The vast majority of these individuals are now surviving well into adulthood. In the 45 years since its introduction, however, there has been increasing recog...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-016-0716-y
更新日期:2016-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Comprehensive discussion of alternative techniques in imaging coronary artery anomalies (CAAs) in different diagnostic scenarios. RECENT FINDINGS:At primary screening, intramural course essentially correlates with stenosis and clinical repercussion in some types of CAAs. Potential clinical aims in im...
journal_title:Current cardiology reports
pub_type: 杂志文章
doi:10.1007/s11886-019-1188-7
更新日期:2019-07-29 00:00:00
abstract::True aneurysms of the pulmonary artery are rare, and are most often due to pulmonary hypertension arising from congenital heart defects. We report the case of a 40-year-old man with an uncorrected patent ductus arteriosus who presented with pulmonary infarction and pneumonia, and subsequently died of cardiac arrest. A...
journal_title:Current cardiology reports
pub_type: 杂志文章
doi:10.1007/s11886-005-0054-y
更新日期:2005-07-01 00:00:00
abstract:PURPOSE OF REVIEW:This review describes the effects of psychological stress on the physiology of the entire vascular system, from individual cellular components to macrovascular and microvascular responses, and highlights the importance of the vascular system in the context of current limitations in cardiac imaging for...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-020-01406-x
更新日期:2020-10-09 00:00:00
abstract::Diastolic dysfunction in patients with hypertension may present as asymptomatic findings on noninvasive testing, or as fulminant pulmonary edema, despite normal left ventricular systolic function. Up to 40% of hypertensive patients presenting with clinical signs of congestive heart failure have normal systolic left ve...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-001-0071-4
更新日期:2001-11-01 00:00:00
abstract::Heart failure is a major public health concern that is frequently complicated by ventricular arrhythmias. Sustained ventricular tachycardia is associated with an increased risk for progressive heart failure and sudden death. We summarize the current management strategies for ventricular tachycardia in heart failure pa...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-011-0182-5
更新日期:2011-06-01 00:00:00
abstract::Radiofrequency ablation is a valuable adjunctive therapy to implantable defibrillators in patients with recurrent monomorphic ventricular tachycardia (VT) after myocardial infarction. Episodes of VT are markedly reduced in most patients, and the major complications are less than 5%. Newer approaches allow successful a...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-003-0092-2
更新日期:2003-09-01 00:00:00
abstract::Antiarrhythmic drugs are widely used, but are of modest efficacy and have important side effects. However, even with the advance of catheter ablation for atrial fibrillation and ventricular tachycardia, antiarrhythmic drugs remain an important tool for treating arrhythmias. Antiarrhythmic drug development has remained...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-013-0410-2
更新日期:2013-10-01 00:00:00
abstract::Ischemic stroke threatens public health dramatically, and demographic changes promise to continue this epidemic. Although medical advances in risk factor modification, hypertensive control, and antiplatelet therapy have mitigated morbidity and mortality of cerebrovascular disease somewhat, stroke still costs billions ...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-007-0005-x
更新日期:2007-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Tricuspid regurgitation is common; however, recognition and diagnosis, clinical outcomes, and management strategies are poorly defined. Here, we will describe the etiology and natural history of tricuspid regurgitation (TR), evaluate existing surgical outcomes data, and review the evolving field of pe...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-017-0920-4
更新日期:2017-09-14 00:00:00
abstract::Patients from racial and ethnic minorities experience higher mortality after cardiac surgery compared to white patients, both during the early postoperative phase as well as long term. A number of factors likely explain poor outcomes in black and minority patients, which include differences in biology, comorbid health...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-015-0587-7
更新日期:2015-05-01 00:00:00
abstract::Primary aldosteronism with a prevalence of 8 % of hypertension and 20 % of pharmacologically resistant hypertension is the most common secondary cause of hypertension. Yet, the diagnosis is missed in the vast majority of patients. Current clinical practice guidelines recommend screening for primary aldosteronism in pa...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-016-0774-1
更新日期:2016-10-01 00:00:00