Cardiac resynchronization therapy in mild heart failure: a review of the REVERSE and MADIT-CRT trials.

abstract：:Fifty thousand Americans suffer an intracerebral hemorrhage (ICH) annually, one third of whom die as a result. Poorly controlled hypertension is the most important risk factor for ICH. Over time it results in pathologic changes to small intracranial vessels, leading to their rupture. All stroke patients, including tho...

journal_title：Current cardiology reports

authors： Tuhrim S

更新日期：2002-03-01 00:00:00

abstract：:Although assessment of traditional coronary heart disease risk factors can often stratify individuals into low- or high-risk categories, additional means are needed to more precisely classify people clinically defined as intermediate-risk, to guide the intensity of risk-reducing therapies. The recognition that inflamm...

journal_title：Current cardiology reports

authors： Corson MA

更新日期：2009-11-01 00:00:00

abstract：:The long QT syndrome (LQTS) and the Brugada syndrome (BrS) are the most common genetic causes of malignant ventricular arrhythmias and sudden cardiac death in young patients with normal cardiac morphology. To date, more than 250 different mutations in seven genes have been identified as causing LQTS, whereas the only ...

journal_title：Current cardiology reports

authors： Goldenberg I,Moss AJ,Zareba W

更新日期：2005-09-01 00:00:00

abstract：:Sodium is an essential nutrient, mostly ingested as salt (sodium chloride). Average sodium intake ranges from 3 to 6 g per day (7.5-15 g/day of salt) in most countries, with regional variations. Increasing levels of sodium intake have a positive association with higher blood pressure. Randomized controlled trials repo...

journal_title：Current cardiology reports

authors： O'Donnell M,Mente A,Yusuf S

更新日期：2014-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This study aims to describe the current state of telestroke clinical applications and policies, in addition to key technical and operational aspects of the telemedicine practice. RECENT FINDINGS:Delivery of telestroke services for neurovascular care expanded from the intravenous alteplase decision an...

journal_title：Current cardiology reports

authors： Dumitrascu OM,Demaerschalk BM

更新日期：2017-09-01 00:00:00

abstract：:Resistant hypertension has evolved as an important global health care problem. Primary aldosteronism is one of several potentially reversible causes of resistant hypertension. Primary aldosteronism can be effectively treated, when recognized, with a mineralocorticoid receptor antagonist, such as spironolactone and epl...

journal_title：Current cardiology reports

authors： Sica DA

更新日期：2011-12-01 00:00:00

abstract：:Aortic stenosis affects many people worldwide with a significant impact on morbidity and mortality with uncorrected, symptomatic aortic valve stenosis carrying mortality of 50% at one year. Degenerative calcific pathology, the most common cause of aortic stenosis, increases in prevalence with age; estimated prevalence...

journal_title：Current cardiology reports

authors： Halim SA,Kiefer TL,Hughes GC,Hurwitz LM,Harrison JK

更新日期：2013-06-01 00:00:00

abstract：:Diastolic dysfunction in patients with hypertension may present as asymptomatic findings on noninvasive testing, or as fulminant pulmonary edema, despite normal left ventricular systolic function. Up to 40% of hypertensive patients presenting with clinical signs of congestive heart failure have normal systolic left ve...

journal_title：Current cardiology reports

authors： Phillips RA,Diamond JA

更新日期：2001-11-01 00:00:00

abstract：:In STEMI, primary PCI restores macrovascular coronary blood flow effectively but microvascular perfusion remains a challenge. Thrombus has the potential to embolize to the microvasculature limiting effective coronary blood flow. Thrombus burden is associated with a higher mortality and manual aspiration thrombectomy h...

journal_title：Current cardiology reports

authors： Alak A,Jolly SS

更新日期：2016-03-01 00:00:00

abstract：:Congestive heart failure is increasing in prevalence in the United States, and associated morbidity and mortality remain high. Aggressive treatment of decompensated heart failure is associated with improved outcomes; however, therapies must be tailored to the presenting characteristics of each patient and most carry a...

journal_title：Current cardiology reports

authors： Hiestand B,Abraham WT

更新日期：2007-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Monoclonal antibodies that inhibit proprotein convertase subtilisin/kexin type 9 (PCSK9) have emerged as a novel approach to low-density lipoprotein cholesterol (LDL-C) lowering. The potential role of PCSK9 inhibitors in clinical practice will be reviewed. RECENT FINDINGS:Clinical trials have demonst...

journal_title：Current cardiology reports

authors： King P,Nicholls SJ

更新日期：2017-08-01 00:00:00

abstract：:The scientific selection of antithrombotic therapy has been dominated by group-based interpretation of data in the form of probability-based statistics in evidence-based medicine. Because the data in large randomized trials are grouped and averaged, the relationship to initial conditions of the patient is lost. There ...

journal_title：Current cardiology reports

authors： Helgason CM

更新日期：2003-03-01 00:00:00

abstract：:Understanding the genetic risk factors for stroke is an essential step to decipher the underlying mechanisms, facilitate the identification of novel therapeutic targets, and optimize the design of prevention strategies. A very small proportion of strokes are attributable to monogenic conditions, the vast majority bein...

journal_title：Current cardiology reports

authors： Chauhan G,Debette S

更新日期：2016-12-01 00:00:00

abstract：:Selective coronary angiography was originally performed through open brachial arteriotomy. Thereafter, the percutaneous Seldinger technique and the use of preformed Judkins-type catheters popularized the femoral approach. More recently, after the first report of successful coronary angiography by the transradial appro...

journal_title：Current cardiology reports

authors： Franchi E,Marino P,Biondi-Zoccai GG,De Luca G,Vassanelli C,Agostoni P

更新日期：2009-09-01 00:00:00

abstract：:Increasing barriers to medical device innovation in the United States including constrained financial resources and rising research costs require that physicians take on greater involvement in medical device development, evaluation, and regulatory processes. Such involvement requires that physicians understand basic a...

journal_title：Current cardiology reports

authors： Sastry A

更新日期：2014-01-01 00:00:00

abstract：:Plasminogen activation potential in the blood is controlled by an equilibrium between plasminogen activators, mainly tissue-type plasminogen activator (t-PA), and inhibitors, mainly plasminogen activator inhibitor (PAI)-1. In cardiovascular practice, imbalance of this fibrinolytic potential is encountered primarily in...

journal_title：Current cardiology reports

authors： Juhan-Vague I,Morange P,Christine Alessi M

更新日期：1999-07-01 00:00:00

abstract：:One of the most highly unexpected reports in recent medical literature was the lack of benefit of estrogen-progestin replacement therapy in cardiovascular disease prevention in postmenopausal women. The ensuing negative view of hormone replacement therapy has now extended to all forms of postmenopausal hormone treatme...

journal_title：Current cardiology reports

authors： Knopp RH,Aikawa K,Knopp EA

更新日期：2003-11-01 00:00:00

abstract：:The most common cause of acute coronary syndrome (ACS) is rupture of an atherosclerotic lesion containing a large necrotic core and a thin fibrous cap followed by acute luminal thrombosis because the rupture of the thin fibrous cap allows contact of the platelets with the highly thrombogenic necrotic core. Pathologic ...

journal_title：Current cardiology reports

authors： Choi SY,Mintz GS

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe lipid abnormalities in diabetes, when they occur and the evidence base for lipid management with established and new drugs to prevent diabetes complications. We also discuss how to manage statin intolerance. RECENT FINDINGS:Statins remain first-line therapy in patients with diabetes, thou...

journal_title：Current cardiology reports

authors： Sillars A,Sattar N

更新日期：2019-11-22 00:00:00

abstract：PURPOSE OF REVIEW:To assess current management strategies for advanced heart failure in adults with congenital heart disease, including heart transplantation and mechanical circulatory support. RECENT FINDINGS:Current data demonstrate that adults with CHD generally experience higher short-term mortality after heart tr...

journal_title：Current cardiology reports

authors： Serfas JD,Patel PA,Krasuski RA

更新日期：2018-08-09 00:00:00

abstract：:Over the past decade, catheter based treatments of an increasing variety of cardiac diseases have expanded dramatically. These advancements became available through new developments and improvements in available devices, as well as increasing expertise of operators. However, arguably it is the innovation and progress ...

journal_title：Current cardiology reports

authors： Perk G,Kronzon I

更新日期：2013-03-01 00:00:00

abstract：:The appropriateness of coronary revascularization for various clinical scenarios has been reviewed formally by several specialty and subspecialty societies resulting in the formulation of scored appropriateness criteria. The goal of the appropriateness criteria is to guide physician decision-making and future research...

journal_title：Current cardiology reports

authors： Summers MR,Patel MR

更新日期：2013-07-01 00:00:00

abstract：:The Fontan operation has been nothing short of revolutionary in its influence on the modern management of patients born with functionally univentricular hearts. The vast majority of these individuals are now surviving well into adulthood. In the 45 years since its introduction, however, there has been increasing recog...

journal_title：Current cardiology reports

authors： Elder RW,Wu FM

更新日期：2016-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Ocular perfusion pressure (OPP) is defined as the difference between BP and intraocular pressure (IOP). With low BP comes low OPP and resultant ischemic damage to the optic nerve, leading to glaucoma progression. The purpose of this article is to review the literature on BP as it relates to glaucoma a...

journal_title：Current cardiology reports

authors： Levine RM,Yang A,Brahma V,Martone JF

更新日期：2017-09-19 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac troponin (cTn) plays an essential role for assessment of outcome in acute coronary syndrome (ACS). However, the prognostic value of cTn is not absolute. In this mini-review, we summarize the evidence on the utility of established biomarkers of left-ventricular dysfunction, hemodynamic stress, ...

journal_title：Current cardiology reports

authors： Eggers KM,Lindahl B

更新日期：2017-04-01 00:00:00

abstract：:As women with congenital heart disease (CHD) approach childbearing age, issues such as pregnancy and contraception need to be addressed. Women with CHD represent a heterogeneous population. While some have simple cardiac lesions and thus have contraceptive risks that are no different from those of the general populati...

journal_title：Current cardiology reports

authors： Silversides CK,Sermer M,Siu SC

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:An examination of the current ACC/AHA and ESC/EAS Guidelines on the management of dyslipidemias for common ground and differences. RECENT FINDINGS:There is much common ground. Both note that ASCVD is, in most people, the product of a number of risk factors, notably tobacco exposure, hyperlipidemia, h...

journal_title：Current cardiology reports

authors： Graham IM,Catapano AL

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute pulmonary embolism (PE) is a common condition associated with high morbidity and mortality. Prior studies have evaluated the role of systemic fibrinolysis and catheter-directed therapy (CDT) in the management of PE. In this review, we examine current data on risk stratification and the appropria...

journal_title：Current cardiology reports

authors： Kosova EC,Desai KR,Schimmel DR

更新日期：2017-06-01 00:00:00

abstract：:On page 2 of the original publication, in the section on TTR Silencers dosing of patisiran in the APOLLO study was stated as being given every 3 months; this is inaccurate as patisiran was dosed every 3 weeks in the APOLLO study. ...

journal_title：Current cardiology reports

authors： Hough A,Wearden J,de Almeida K,Kaiser S

更新日期：2020-09-28 00:00:00

abstract：:Randomized clinical trials have established that lipid- lowering pharmacologic therapy can substantially reduce morbidity and mortality in patients with known coronary artery disease (CAD). Researchers are now working to define the role of lipid-lowering agents in the primary prevention of CAD to extend their benefit ...

journal_title：Current cardiology reports

authors： Nass CM,Wiviott SD,Allen JK,Post WS,Blumenthal aR

更新日期：2000-09-01 00:00:00