Abstract:
BACKGROUND:EMG-to-force estimation based on muscle models, for voluntary contraction has many applications in human motion analysis. The so-called Hill model is recognized as a standard model for this practical use. However, it is a phenomenological model whereby muscle activation, force-length and force-velocity properties are considered independently. Perreault reported Hill modeling errors were large for different firing frequencies, level of activation and speed of contraction. It may be due to the lack of coupling between activation and force-velocity properties. In this paper, we discuss EMG-force estimation with a multi-scale physiology based model, which has a link to underlying crossbridge dynamics. Differently from the Hill model, the proposed method provides dual dynamics of recruitment and calcium activation. METHODS:The ankle torque was measured for the plantar flexion along with EMG measurements of the medial gastrocnemius (GAS) and soleus (SOL). In addition to Hill representation of the passive elements, three models of the contractile parts have been compared. Using common EMG signals during isometric contraction in four able-bodied subjects, torque was estimated by the linear Hill model, the nonlinear Hill model and the multi-scale physiological model that refers to Huxley theory. The comparison was made in normalized scale versus the case in maximum voluntary contraction. RESULTS:The estimation results obtained with the multi-scale model showed the best performances both in fast-short and slow-long term contraction in randomized tests for all the four subjects. The RMS errors were improved with the nonlinear Hill model compared to linear Hill, however it showed limitations to account for the different speed of contractions. Average error was 16.9% with the linear Hill model, 9.3% with the modified Hill model. In contrast, the error in the multi-scale model was 6.1% while maintaining a uniform estimation performance in both fast and slow contractions schemes. CONCLUSIONS:We introduced a novel approach that allows EMG-force estimation based on a multi-scale physiology model integrating Hill approach for the passive elements and microscopic cross-bridge representations for the contractile element. The experimental evaluation highlights estimation improvements especially a larger range of contraction conditions with integration of the neural activation frequency property and force-velocity relationship through cross-bridge dynamics consideration.
journal_name
Biomed Eng Onlinejournal_title
Biomedical engineering onlineauthors
Hayashibe M,Guiraud Ddoi
10.1186/1475-925X-12-86subject
Has Abstractpub_date
2013-09-04 00:00:00pages
86issn
1475-925Xpii
1475-925X-12-86journal_volume
12pub_type
杂志文章abstract:BACKGROUND:Quantizing the Breast Imaging Reporting and Data System (BI-RADS) criteria into different categories with the single ultrasound modality has always been a challenge. To achieve this, we proposed a two-stage grading system to automatically evaluate breast tumors from ultrasound images into five categories bas...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0626-5
更新日期:2019-01-24 00:00:00
abstract:BACKGROUND:The emergence of skin substitutes provides a new approach for the treatment of wound repair and healing. The consistent and steady release of angiogenic factors is an important factor in the promotion of angiogenesis in skin substitutes, which usually lack, yet need, a vascular network. METHODS:In this stud...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-12-134
更新日期:2013-12-31 00:00:00
abstract:BACKGROUND:Current devices for measuring muscle contraction in vivo have limited accuracy in establishing and re-establishing the optimum muscle length. They are variable in the reproducibility to determine the muscle contraction at this length, and often do not maintain precise conditions during the examination. Conse...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-6-1
更新日期:2007-01-02 00:00:00
abstract::Telepointer is a powerful tool in the telemedicine system that enhances the effectiveness of long-distance communication. Telepointer has been tested in telemedicine, and has potential to a big influence in improving quality of health care, especially in the rural area. A telepointer system works by sending additional...
journal_title:Biomedical engineering online
pub_type: 杂志文章,评审
doi:10.1186/1475-925X-12-21
更新日期:2013-03-09 00:00:00
abstract:BACKGROUND:The paper presents an approach and computer-aided method of numerical evaluation of the quality of porous membranes used as scaffolds for cultivation of chondrocytes in regeneration of biological tissues. MATERIALS:The scanning electron microscope (SEM) images of 300× and 1000× magnification presenting the ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0481-9
更新日期:2018-05-30 00:00:00
abstract:BACKGROUND:The main problem of tremor is the damage caused to the quality of the life of patients, especially those at more advanced ages. There is not a consensus yet about the origins of this disorder, but it can be examined in the correlations between the biological signs of aging and the tremor characteristics. ME...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-9-29
更新日期:2010-06-22 00:00:00
abstract:BACKGROUND:Image segmentation is an essential and non trivial task in computer vision and medical image analysis. Computed tomography (CT) is one of the most accessible medical examination techniques to visualize the interior of a patient's body. Among different computer-aided diagnostic systems, the applications dedic...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0456-x
更新日期:2018-02-27 00:00:00
abstract:OBJECTIVE:Heart rate variability (HRV) analysis, which is an important tool for activity assessment of the cardiac autonomic nervous system, very often includes the estimation of power spectra for series of interbeat intervals (IBI). Ectopic beats and artifacts have a destructive effect on the standard methods (Fourier...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-13-138
更新日期:2014-09-23 00:00:00
abstract:BACKGROUND:Human embryonic stem cell derived cardiomyocytes (hESC-CMs) hold high potential for basic and applied cardiovascular research. The development of a reliable simulation platform able to mimic the functional properties of hESC-CMs would be of considerable value to perform preliminary test complementing in vitr...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-11-61
更新日期:2012-08-28 00:00:00
abstract::Advances in biomaterials and the need for patient-specific bone scaffolds require modern manufacturing approaches in addition to a design strategy. Hybrid materials such as those with functionally graded properties are highly needed in tissue replacement and repair. However, their constituents, proportions, sizes, con...
journal_title:Biomedical engineering online
pub_type: 杂志文章,评审
doi:10.1186/s12938-020-00810-2
更新日期:2020-09-03 00:00:00
abstract:BACKGROUND:Computer-assisted arrhythmia recognition is critical for the management of cardiac disorders. Various techniques have been utilized to classify arrhythmias. Generally, these techniques classify two or three arrhythmias or have significantly large processing times. A simpler autoregressive modeling (AR) techn...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925x-1-5
更新日期:2002-11-13 00:00:00
abstract:BACKGROUND:STAR is a model-based, personalised, risk-based dosing approach for glycaemic control (GC) in critically ill patients. STAR provides safe, effective control to nearly all patients, using 1-3 hourly measurement and intervention intervals. However, the average 11-12 measurements per day required can be a clini...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-020-00771-6
更新日期:2020-04-29 00:00:00
abstract:BACKGROUND:Biomedical named entity recognition (Bio-NER) is a fundamental task in handling biomedical text terms, such as RNA, protein, cell type, cell line, and DNA. Bio-NER is one of the most elementary and core tasks in biomedical knowledge discovery from texts. The system described here is developed by using the Bi...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0573-6
更新日期:2018-11-06 00:00:00
abstract:BACKGROUND:A specific problem using the public access defibrillators (PADs) arises at the railway stations. Some countries as Germany, Austria, Switzerland, Norway and Sweden are using AC railroad net power-supply system with rated 16.7 Hz frequency modulated from 15.69 Hz to 17.36 Hz. The power supply frequency contam...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-4-16
更新日期:2005-03-15 00:00:00
abstract:BACKGROUND:In this paper we present a novel scene retargeting technique to reduce the visual scene while maintaining the size of the key features. The algorithm is scalable to implementation onto portable devices, and thus, has potential for augmented reality systems to provide visual support for those with tunnel visi...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-9-52
更新日期:2010-09-16 00:00:00
abstract:BACKGROUND:Voice disorders affect patients profoundly, and acoustic tools can potentially measure voice function objectively. Disordered sustained vowels exhibit wide-ranging phenomena, from nearly periodic to highly complex, aperiodic vibrations, and increased "breathiness". Modelling and surrogate data studies have s...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-6-23
更新日期:2007-06-26 00:00:00
abstract:BACKGROUND:Biomechanical and clinical parameters contribute very closely to functional evaluations of the knee joint. To better understand knee osteoarthritis joint function, the association between a set of knee biomechanical data and a set of clinical parameters of an osteoarthritis population (OA) is investigated in...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0676-8
更新日期:2019-05-15 00:00:00
abstract:BACKGROUND:Robot-based joint-testing systems (RJTS) can be used to perform unconstrained laxity tests, measuring the stiffness of a degree of freedom (DOF) of the joint at a fixed flexion angle while allowing the other DOFs unconstrained movement. Previous studies using the force-position hybrid (FPH) control method pr...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0195-9
更新日期:2016-06-07 00:00:00
abstract:BACKGROUND:Stroke is one of the major causes of morbidity and mortality. Its recovery and treatment depends on close clinical monitoring by a clinician especially during the first few hours after the onset of stroke. Patients who do not exhibit early motor recovery post thrombolysis may benefit from more aggressive tre...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-12-33
更新日期:2013-04-16 00:00:00
abstract:BACKGROUND:Shape of the dental root canal is highly patient specific. Automated identification methods of the medial line of dental root canals and the reproduction of their 3D shape can be beneficial for planning endodontic interventions as severely curved root canals or multi-rooted teeth may pose treatment challenge...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-11-81
更新日期:2012-10-29 00:00:00
abstract:INTRODUCTION:This paper shows the influence of a measurement method of features in the diagnosis of Hashimoto's disease. Sensitivity of the algorithm to changes in the parameters of the ROI, namely shift, resizing and rotation, has been presented. The obtained results were also compared to the methods known from the li...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-11-91
更新日期:2012-11-28 00:00:00
abstract:BACKGROUND:The usability of dexterous hand prostheses is still hampered by the lack of natural and effective control strategies. A decoding strategy based on the processing of descending efferent neural signals recorded using peripheral neural interfaces could be a solution to such limitation. Unfortunately, this choic...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0659-9
更新日期:2019-04-08 00:00:00
abstract:BACKGROUND:To determine how the mechanical property and micro structure affect tissue regeneration and angiogenesis, three types of scaffolds were studied. Acellular dermal matrices (ADM), produced from human skin by removing the epidermis and cells, has been widely used in wound healing because of its high mechanical ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-12-125
更新日期:2013-12-04 00:00:00
abstract:BACKGROUND:Areas with high frequency activity within the atrium are thought to be 'drivers' of the rhythm in patients with atrial fibrillation (AF) and ablation of these areas seems to be an effective therapy in eliminating DF gradient and restoring sinus rhythm. Clinical groups have applied the traditional FFT-based a...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0143-8
更新日期:2016-03-08 00:00:00
abstract:BACKGROUND:The evaluation, verification and comparison of different numerical heart models are difficult without a commonly available database that could be utilized as a reference. Our aim was to compile an exemplary dataset. METHODS:The following methods were employed: Magnetic Resonance Imaging (MRI) of heart and t...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-10-11
更新日期:2011-01-27 00:00:00
abstract:BACKGROUND:In a typical electrophysiological experiment, especially one that includes studying animal behavior, the data collected normally contain spikes, local field potentials, behavioral responses and other associated data. In order to obtain informative results, the data must be analyzed simultaneously with the ex...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-017-0419-7
更新日期:2017-11-13 00:00:00
abstract:BACKGROUND:Heart rate can be used to prescribe exercise intensity for development and maintenance of cardiorespiratory fitness. The aim of this study was to identify the dynamics of heart rate response during moderate-to-vigorous treadmill exercise and to explore parameter dependencies with respect to time, intensity l...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0112-7
更新日期:2015-12-21 00:00:00
abstract:BACKGROUND:Mitral valve failure can require repair or replacement. Replacement bioprosthetic valves are treated with glutaraldehyde prior to implantation. The aim of this study was to determine the changes in mechanical properties following glutaraldehyde fixation of mitral valve chordae. METHODS:To investigate the im...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0524-2
更新日期:2018-07-13 00:00:00
abstract:BACKGROUND:The electroencephalography (EEG) signals are known to involve the firings of neurons in the brain. The P300 wave is a high potential caused by an event-related stimulus. The detection of P300s included in the measured EEG signals is widely investigated. The difficulties in detecting them are that they are mi...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-10-83
更新日期:2011-09-23 00:00:00
abstract:BACKGROUND:Since the first well-known electrocardiogram (ECG) delineator based on Wavelet Transform (WT) presented by Li et al. in 1995, a significant research effort has been devoted to the exploitation of this promising method. Its ability to reliably delineate the major waveform components (mono- or bi-phasic P wave...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-10-23
更新日期:2011-04-03 00:00:00