Exploiting nonlinear recurrence and fractal scaling properties for voice disorder detection.

Abstract:

BACKGROUND:Voice disorders affect patients profoundly, and acoustic tools can potentially measure voice function objectively. Disordered sustained vowels exhibit wide-ranging phenomena, from nearly periodic to highly complex, aperiodic vibrations, and increased "breathiness". Modelling and surrogate data studies have shown significant nonlinear and non-Gaussian random properties in these sounds. Nonetheless, existing tools are limited to analysing voices displaying near periodicity, and do not account for this inherent biophysical nonlinearity and non-Gaussian randomness, often using linear signal processing methods insensitive to these properties. They do not directly measure the two main biophysical symptoms of disorder: complex nonlinear aperiodicity, and turbulent, aeroacoustic, non-Gaussian randomness. Often these tools cannot be applied to more severe disordered voices, limiting their clinical usefulness. METHODS:This paper introduces two new tools to speech analysis: recurrence and fractal scaling, which overcome the range limitations of existing tools by addressing directly these two symptoms of disorder, together reproducing a "hoarseness" diagram. A simple bootstrapped classifier then uses these two features to distinguish normal from disordered voices. RESULTS:On a large database of subjects with a wide variety of voice disorders, these new techniques can distinguish normal from disordered cases, using quadratic discriminant analysis, to overall correct classification performance of 91.8 +/- 2.0%. The true positive classification performance is 95.4 +/- 3.2%, and the true negative performance is 91.5 +/- 2.3% (95% confidence). This is shown to outperform all combinations of the most popular classical tools. CONCLUSION:Given the very large number of arbitrary parameters and computational complexity of existing techniques, these new techniques are far simpler and yet achieve clinically useful classification performance using only a basic classification technique. They do so by exploiting the inherent nonlinearity and turbulent randomness in disordered voice signals. They are widely applicable to the whole range of disordered voice phenomena by design. These new measures could therefore be used for a variety of practical clinical purposes.

journal_name

Biomed Eng Online

authors

Little MA,McSharry PE,Roberts SJ,Costello DA,Moroz IM

doi

10.1186/1475-925X-6-23

subject

Has Abstract

pub_date

2007-06-26 00:00:00

pages

23

issn

1475-925X

pii

1475-925X-6-23

journal_volume

6

pub_type

杂志文章
  • In vitro evaluation of Panax notoginseng Rg1 released from collagen/chitosan-gelatin microsphere scaffolds for angiogenesis.

    abstract:BACKGROUND:The emergence of skin substitutes provides a new approach for the treatment of wound repair and healing. The consistent and steady release of angiogenic factors is an important factor in the promotion of angiogenesis in skin substitutes, which usually lack, yet need, a vascular network. METHODS:In this stud...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-12-134

    authors: Zheng Y,Feng Z,You C,Jin Y,Hu X,Wang X,Han C

    更新日期:2013-12-31 00:00:00

  • Assessment of significance of features acquired from thyroid ultrasonograms in Hashimoto's disease.

    abstract:INTRODUCTION:This paper concerns the analysis of the features obtained from thyroid ultrasound images in left and right transverse and longitudinal sections. In the image analysis, the thyroid lobe is treated as a texture for healthy subjects and patients with Hashimoto's disease. The applied methods of analysis and im...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-11-48

    authors: Koprowski R,Zieleźnik W,Wróbel Z,Małyszek J,Stępień B,Wójcik W

    更新日期:2012-08-16 00:00:00

  • An artifacts removal post-processing for epiphyseal region-of-interest (EROI) localization in automated bone age assessment (BAA).

    abstract:BACKGROUND:Segmentation is the most crucial part in the computer-aided bone age assessment. A well-known type of segmentation performed in the system is adaptive segmentation. While providing better result than global thresholding method, the adaptive segmentation produces a lot of unwanted noise that could affect the ...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-10-87

    authors: Chai HY,Wee LK,Swee TT,Salleh ShH,Chea LY

    更新日期:2011-09-28 00:00:00

  • Risk and reward: extending stochastic glycaemic control intervals to reduce workload.

    abstract:BACKGROUND:STAR is a model-based, personalised, risk-based dosing approach for glycaemic control (GC) in critically ill patients. STAR provides safe, effective control to nearly all patients, using 1-3 hourly measurement and intervention intervals. However, the average 11-12 measurements per day required can be a clini...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-020-00771-6

    authors: Uyttendaele V,Knopp JL,Shaw GM,Desaive T,Chase JG

    更新日期:2020-04-29 00:00:00

  • Robust phase-based texture descriptor for classification of breast ultrasound images.

    abstract:BACKGROUND:Classification of breast ultrasound (BUS) images is an important step in the computer-aided diagnosis (CAD) system for breast cancer. In this paper, a novel phase-based texture descriptor is proposed for efficient and robust classifiers to discriminate benign and malignant tumors in BUS images. METHOD:The p...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-015-0022-8

    authors: Cai L,Wang X,Wang Y,Guo Y,Yu J,Wang Y

    更新日期:2015-03-24 00:00:00

  • Reducing the airflow waveform distortions from breathing style and body position with improved calibration of respiratory effort belts.

    abstract:BACKGROUND:Respiratory effort belt measurement is a widely used method to monitor respiration. Signal waveforms of respiratory volume and flow may indicate pathological signs of several diseases and, thus, it would be highly desirable to predict them accurately. Calibrated effort belts are sufficiently accurate for est...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-12-97

    authors: Seppänen TM,Alho OP,Seppänen T

    更新日期:2013-09-28 00:00:00

  • Voluntary EMG-to-force estimation with a multi-scale physiological muscle model.

    abstract:BACKGROUND:EMG-to-force estimation based on muscle models, for voluntary contraction has many applications in human motion analysis. The so-called Hill model is recognized as a standard model for this practical use. However, it is a phenomenological model whereby muscle activation, force-length and force-velocity prope...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-12-86

    authors: Hayashibe M,Guiraud D

    更新日期:2013-09-04 00:00:00

  • NeoAnalysis: a Python-based toolbox for quick electrophysiological data processing and analysis.

    abstract:BACKGROUND:In a typical electrophysiological experiment, especially one that includes studying animal behavior, the data collected normally contain spikes, local field potentials, behavioral responses and other associated data. In order to obtain informative results, the data must be analyzed simultaneously with the ex...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-017-0419-7

    authors: Zhang B,Dai J,Zhang T

    更新日期:2017-11-13 00:00:00

  • 16-Channel biphasic current-mode programmable charge balanced neural stimulation.

    abstract:BACKGROUND:Neural stimulation is an important method used to activate or inhibit action potentials of the neuronal anatomical targets found in the brain, central nerve and peripheral nerve. The neural stimulator system produces biphasic pulses that deliver balanced charge into tissue from single or multichannel electro...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-017-0385-0

    authors: Li X,Zhong S,Morizio J

    更新日期:2017-08-14 00:00:00

  • Effect of amplitude and duration of impulsive pressure on endothelial permeability in in vitro fluid percussion trauma.

    abstract:BACKGROUND:Intracranial pressure changes during head impact cause brain injuries such as vasogenic edema and cerebral contusion. However, the influence of impulsive pressure on endothelial function has not yet been fully studied in vitro. In this study, we developed a pressure loading device that produced positive and ...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-13-44

    authors: Nakadate H,Inuzuka K,Akanuma S,Kakuta A,Aomura S

    更新日期:2014-04-16 00:00:00

  • Simulating the swelling and deformation behaviour in soft tissues using a convective thermal analogy.

    abstract:BACKGROUND:It is generally accepted that cartilage adaptation and degeneration are mechanically mediated. Investigating the swelling behaviour of cartilage is important because the stress and strain state of cartilage is associated with the swelling and deformation behaviour. It is well accepted that the swelling of so...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925x-1-8

    authors: Wu JZ,Herzog W

    更新日期:2002-12-19 00:00:00

  • Influence of vascular geometry on local hemodynamic parameters: phantom and small rodent study.

    abstract:BACKGROUND:Many studies have demonstrated that the geometry of the carotid bifurcation enables prediction of blood flow variation associated with atherosclerotic plaque formation. The phase angle between the arterial wall circumferential strain and its instantaneous wall shear stress is known as stress phase angle (SPA...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-018-0458-8

    authors: Niu L,Zhu X,Pan M,Derek A,Xu L,Meng L,Zheng H

    更新日期:2018-03-02 00:00:00

  • Hemodynamic effects of perfusion level of peripheral ECMO on cardiovascular system.

    abstract:BACKGROUND:Peripheral ECMO is an effective cardiopulmonary support in clinical. The perfusion level could directly influence the performances and complications. However, there are few studies on the effects of the perfusion level on hemodynamics of peripheral ECMO. METHODS:The geometric model of cardiovascular system ...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-018-0493-5

    authors: Gu K,Zhang Z,Gao B,Chang Y,Wan F

    更新日期:2018-05-09 00:00:00

  • Three-dimensional dominant frequency mapping using autoregressive spectral analysis of atrial electrograms of patients in persistent atrial fibrillation.

    abstract:BACKGROUND:Areas with high frequency activity within the atrium are thought to be 'drivers' of the rhythm in patients with atrial fibrillation (AF) and ablation of these areas seems to be an effective therapy in eliminating DF gradient and restoring sinus rhythm. Clinical groups have applied the traditional FFT-based a...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-016-0143-8

    authors: Salinet JL,Masca N,Stafford PJ,Ng GA,Schlindwein FS

    更新日期:2016-03-08 00:00:00

  • Human coronary plaque wall thickness correlated positively with flow shear stress and negatively with plaque wall stress: an IVUS-based fluid-structure interaction multi-patient study.

    abstract:BACKGROUND:Atherosclerotic plaque progression and rupture are believed to be associated with mechanical stress conditions. In this paper, patient-specific in vivo intravascular ultrasound (IVUS) coronary plaque image data were used to construct computational models with fluid-structure interaction (FSI) and cyclic bend...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-13-32

    authors: Fan R,Tang D,Yang C,Zheng J,Bach R,Wang L,Muccigrosso D,Billiar K,Zhu J,Ma G,Maehara A,Mintz GS

    更新日期:2014-03-26 00:00:00

  • Influence of head models on EEG simulations and inverse source localizations.

    abstract:BACKGROUND:The structure of the anatomical surfaces, e.g., CSF and gray and white matter, could severely influence the flow of volume currents in a head model. This, in turn, will also influence the scalp potentials and the inverse source localizations. This was examined in detail with four different human head models....

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-5-10

    authors: Ramon C,Schimpf PH,Haueisen J

    更新日期:2006-02-08 00:00:00

  • Effects of 8-week swimming training on carotid arterial stiffness and hemodynamics in young overweight adults.

    abstract:BACKGROUND:Exercise has been found to either reduce or increase arterial stiffness. Land-based exercise modalities have been documented as effective physical therapies to decrease arterial stiffness. However, these land-based exercise modalities may not be suitable for overweight individuals, in terms of risks of joint...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-016-0274-y

    authors: Yuan WX,Liu HB,Gao FS,Wang YX,Qin KR

    更新日期:2016-12-28 00:00:00

  • Effect of glutaraldehyde based cross-linking on the viscoelasticity of mitral valve basal chordae tendineae.

    abstract:BACKGROUND:Mitral valve failure can require repair or replacement. Replacement bioprosthetic valves are treated with glutaraldehyde prior to implantation. The aim of this study was to determine the changes in mechanical properties following glutaraldehyde fixation of mitral valve chordae. METHODS:To investigate the im...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-018-0524-2

    authors: Constable M,Burton HE,Lawless BM,Gramigna V,Buchan KG,Espino DM

    更新日期:2018-07-13 00:00:00

  • Possibility of reconstruction of dental plaster cast from 3D digital study models.

    abstract:OBJECTIVES:To compare traditional plaster casts, digital models and 3D printed copies of dental plaster casts based on various criteria. To determine whether 3D printed copies obtained using open source system RepRap can replace traditional plaster casts in dental practice. To compare and contrast the qualities of two ...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-12-49

    authors: Kasparova M,Grafova L,Dvorak P,Dostalova T,Prochazka A,Eliasova H,Prusa J,Kakawand S

    更新日期:2013-05-31 00:00:00

  • Correction to: Effects of astrocyte on neuronal outgrowth in a layered 3D structure.

    abstract::It was highlighted that the original article [1] contained an error in the Acknowledgments section. ...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章,已发布勘误

    doi:10.1186/s12938-019-0707-5

    authors: Fang A,Li D,Hao Z,Wang L,Pan B,Gao L,Qu X,He J

    更新日期:2019-08-08 00:00:00

  • Reviewing the connection between speech and obstructive sleep apnea.

    abstract:BACKGROUND:Sleep apnea (OSA) is a common sleep disorder characterized by recurring breathing pauses during sleep caused by a blockage of the upper airway (UA). The altered UA structure or function in OSA speakers has led to hypothesize the automatic analysis of speech for OSA assessment. In this paper we critically rev...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-016-0138-5

    authors: Espinoza-Cuadros F,Fernández-Pozo R,Toledano DT,Alcázar-Ramírez JD,López-Gonzalo E,Hernández-Gómez LA

    更新日期:2016-02-20 00:00:00

  • Colonoscopy procedure simulation: virtual reality training based on a real time computational approach.

    abstract:BACKGROUND:Colonoscopy plays an important role in the clinical screening and management of colorectal cancer. The traditional 'see one, do one, teach one' training style for such invasive procedure is resource intensive and ineffective. Given that colonoscopy is difficult, and time-consuming to master, the use of virtu...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-018-0433-4

    authors: Wen T,Medveczky D,Wu J,Wu J

    更新日期:2018-01-25 00:00:00

  • Classification of voice disorder in children with cochlear implantation and hearing aid using multiple classifier fusion.

    abstract:BACKGROUND:Speech production and speech phonetic features gradually improve in children by obtaining audio feedback after cochlear implantation or using hearing aids. The aim of this study was to develop and evaluate automated classification of voice disorder in children with cochlear implantation and hearing aids. ME...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-10-3

    authors: Mahmoudi Z,Rahati S,Ghasemi MM,Asadpour V,Tayarani H,Rajati M

    更新日期:2011-01-14 00:00:00

  • Translational-circular scanning for magneto-acoustic tomography with current injection.

    abstract:BACKGROUND:Magneto-acoustic tomography with current injection involves using electrical impedance imaging technology. To explore the potential applications in imaging biological tissue and enhance image quality, a new scan mode for the transducer is proposed that is based on translational and circular scanning to recor...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-016-0125-x

    authors: Wang S,Ma R,Zhang S,Yin T,Liu Z

    更新日期:2016-01-27 00:00:00

  • Influence of the measurement method of features in ultrasound images of the thyroid in the diagnosis of Hashimoto's disease.

    abstract:INTRODUCTION:This paper shows the influence of a measurement method of features in the diagnosis of Hashimoto's disease. Sensitivity of the algorithm to changes in the parameters of the ROI, namely shift, resizing and rotation, has been presented. The obtained results were also compared to the methods known from the li...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-11-91

    authors: Koprowski R,Korzyńska A,Wróbel Z,Zieleźnik W,Witkowska A,Małyszek J,Wójcik W

    更新日期:2012-11-28 00:00:00

  • Estimation of pelvis kinematics in level walking based on a single inertial sensor positioned close to the sacrum: validation on healthy subjects with stereophotogrammetric system.

    abstract:BACKGROUND:Kinematics measures from inertial sensors have a value in the clinical assessment of pathological gait, to track quantitatively the outcome of interventions and rehabilitation programs. To become a standard tool for clinicians, it is necessary to evaluate their capability to provide reliable and comprehensib...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-13-146

    authors: Buganè F,Benedetti MG,D'Angeli V,Leardini A

    更新日期:2014-10-21 00:00:00

  • The effect of inlet and outlet boundary conditions in image-based CFD modeling of aortic flow.

    abstract:BACKGROUND:Computational modeling of cardiovascular flow is a growing and useful field, but such simulations usually require the researcher to guess the flow's inlet and outlet conditions since they are difficult and expensive to measure. It is critical to determine the amount of uncertainty introduced by these assumpt...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-018-0497-1

    authors: Madhavan S,Kemmerling EMC

    更新日期:2018-05-30 00:00:00

  • Infrared thermography fails to visualize stimulation-induced meridian-like structures: comment by Rixin Chen and Zhimai Lv and reply from Gerhard Litscher.

    abstract::A comment on G. Litscher: Infrared thermography fails to visualize stimulation-induced meridian-like structures. Biomed. Eng. OnLine 2005, 4:38 (15 June 2005), with a response by the author. ...

    journal_title:Biomedical engineering online

    pub_type: 评论,信件

    doi:10.1186/1475-925X-10-80

    authors: Chen R,Lv Z

    更新日期:2011-09-11 00:00:00

  • Telepointer technology in telemedicine: a review.

    abstract::Telepointer is a powerful tool in the telemedicine system that enhances the effectiveness of long-distance communication. Telepointer has been tested in telemedicine, and has potential to a big influence in improving quality of health care, especially in the rural area. A telepointer system works by sending additional...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章,评审

    doi:10.1186/1475-925X-12-21

    authors: Abdul Karim R,Zakaria NF,Zulkifley MA,Mustafa MM,Sagap I,Md Latar NH

    更新日期:2013-03-09 00:00:00

  • A computational model study of the influence of the anatomy of the circle of willis on cerebral hyperperfusion following carotid artery surgery.

    abstract:BACKGROUND:Cerebral hyperperfusion syndrome develops in a small subset of patients following carotid artery surgery (CAS) performed to treat severe carotid artery stenosis. This syndrome has been found to have a close correlation with cerebral hyperperfusion occurring after CAS. The purpose of this study is to investig...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-10-84

    authors: Liang F,Fukasaku K,Liu H,Takagi S

    更新日期:2011-09-23 00:00:00