Laser speckle flowgraphy for differentiating between nonarteritic ischemic optic neuropathy and anterior optic neuritis.

abstract：PURPOSE:To determine whether exposure to ozonated solution alters the morphology of corneal endothelial cells in rats and to examine the protective effect of ascorbic acid. METHODS:The anterior chambers of rat eyes were filled with 4 ppm of ozonated solution. Some were left in that state, while others were flushed out...

journal_title：Japanese journal of ophthalmology

authors： Suzuki H,Sato S,Murano N,Matsui H,Oharazawa H,Takahashi H

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To examine using the folds of the retinal pigment epithelium (RPE) to diagnose Vogt-Koyanagi-Harada (VKH) disease. METHODS:Retrospective clinical review of 57 Japanese patients between July 2005 and April 2009. Optical coherence tomography (OCT), fundus photographs and fluorescein angiography (FA) were studi...

journal_title：Japanese journal of ophthalmology

authors： Kato Y,Yamamoto Y,Tabuchi H,Fukushima A

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:To evaluate the changes in aqueous flare in psoriasis patients and to identify the factors that influence the level of aqueous flare. METHODS:We examined the 68 eyes of 34 psoriasis patients and the 68 eyes of 34 healthy subjects with a laser flare-cell meter. Complete dermatologic and ophthalmic examinations ...

journal_title：Japanese journal of ophthalmology

authors： Okamoto F,Umebayasi Y,Ohtsuka F,Hommura S

更新日期：2001-03-01 00:00:00

abstract：:Astrocytes were cultured from the cerebral cortices of newborn rabbits and were so confirmed by staining of the glial fibrillary acidic protein (GFAP). In Experiment I, the astrocytes of newborn rabbits of both sexes from one mother were pooled and suspended in a culture medium, and approximately 1-2 X 10(4) cells wer...

journal_title：Japanese journal of ophthalmology

authors： Mishima N,Yamashita H,Ishii Y,Hori S

更新日期：1989-01-01 00:00:00

abstract：:A computerized digital image analysis system was developed to evaluate the retinal nerve fiber layer (RNFL) by red-free fundus photography. The image intensity of the RNFL was computed for 30 degrees between the disc and macula. Thirty early open-angle glaucoma patients and 30 normal age-matched subjects were examined...

journal_title：Japanese journal of ophthalmology

authors： Yamazaki Y,Miyazawa T,Yamada H

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To investigate the changes in the electrolyte and protein concentrations in the vitreous of 3-week-old chicks with form-deprivation myopia (FDM). METHODS:FDM was induced in 2-day-old male white leghorn chicks by covering the left eye with a translucent plastic goggle and leaving the right eye uncovered to serv...

journal_title：Japanese journal of ophthalmology

authors： Seko Y,Shimokawa H,Pang J,Tokoro T

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Schwannoma arising from the ciliary body is a rare intraocular neoplasm, and most cases previously reported were diagnosed histopathologically after eyeball enucleation because of a diagnosis of ciliary body melanoma. CASE:A case of ciliary body schwannoma was dissected locally. OBSERVATIONS:A 19-year-old ...

journal_title：Japanese journal of ophthalmology

authors： Goto H,Mori H,Shirato S,Usui M

更新日期：2006-11-01 00:00:00

abstract：PURPOSE:The purpose of this study was to estimate the optimal size of visual field test for detecting longitudinal changes in retinitis pigmentosa (RP) by dividing the visual field. METHODS:We reviewed the results of 10° static visual field tests in 19 eyes of 19 RP patients. Sixty-eight numeric value points were divi...

journal_title：Japanese journal of ophthalmology

authors： Ogino K,Otani A,Oishi A,Kurimoto M,Sekiya T,Yoshimura N

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:Remodeling of the extracellular matrix occurs in the lamina cribrosa in progressed glaucomatous optic nerve damage including disc cupping. We examined immunohistochemical changes in the transforming growth factor (TGF)-beta and platelet-derived growth factor (PDGF) in the optic nerve head in an experimentally i...

journal_title：Japanese journal of ophthalmology

authors： Fukuchi T,Ueda J,Hanyu T,Abe H,Sawaguchi S

更新日期：2001-11-01 00:00:00

abstract：:Changes in the distribution pattern of chloride ions were studied in the embryonic chicken retinal pigment epithelium (RPE), chloride ions being deposited as silver chloride (AgCl) in the RPE and observed by electron microscope. Before the 7th day after fertilization, the chloride ions did not accumulate anywhere in t...

journal_title：Japanese journal of ophthalmology

authors： Yamashita H,Yamamoto T

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:The involvement of cytokines and chemokines in vitreous fluid is important in the development and progression of diabetic retinopathy (DR) and central retinal vein occlusion (CRVO). In this study, the concentrations of cytokines and chemokines in the vitreous fluid of eyes with DR and CRVO were measured and com...

journal_title：Japanese journal of ophthalmology

authors： Suzuki Y,Nakazawa M,Suzuki K,Yamazaki H,Miyagawa Y

更新日期：2011-05-01 00:00:00

abstract：:Silicone oil was injected into the eyes of 28 rabbits. Utilizing the specific affinity of osmium tetroxide for lipids, the pathological features and histochemical localization of silicone oil within the retina were studied. This osmium tetroxide technique makes it possible to identify the presence of silicone oil part...

journal_title：Japanese journal of ophthalmology

authors： Shikishima K,Ohki K,Machi N,Sano Y

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:To determine the spatial distribution types of macular pigment (MP) in elderly Japanese individuals and to consider their origin. STUDY DESIGN:Observational case series. METHODS:Local MP optical density (MPOD) at some eccentricities and MP volume were measured using the MPOD module of a MultiColor Spectralis ...

journal_title：Japanese journal of ophthalmology

authors： Obana A,Gohto Y,Sasano H,Gellermann W,Sharifzadeh M,Seto T,Bernstein PS

更新日期：2020-03-01 00:00:00

abstract：:Characteristics of the distribution of cytoskeletal and contractile elements in cultured human trabecular cells were studied using the immunofluorescence method. Actin microfilaments exhibited stress fiber images which were observed throughout the cell body in a parallel pattern and were concentrated in the cell perip...

journal_title：Japanese journal of ophthalmology

authors： Tamura M,Iwamoto Y,Nakatsuka K,Yamanouchi U

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:In a previous study we demonstrated that the progression of the disease retinitis pigmentosa (RP) can be readily monitored by the mean deviation (MD) measured by Humphrey central 10-2 perimetry, which assesses the sensitivity distribution in the macular area in eyes affected by RP. In the present study, we inve...

journal_title：Japanese journal of ophthalmology

authors： Abe K,Iijima H,Hirakawa H,Tsukahara Y,Toda Y

更新日期：2002-09-01 00:00:00

abstract：PURPOSE:To perform a retrospective study to evaluate the long-term outcome of systemic cyclosporine treatment as an adjunct to topical corticosteroid treatment after penetrating keratoplasty (PKP). METHODS:Twenty-six high-risk patients (27 eyes) who received systemic cyclosporine following PKP for an average of 5.4 mo...

journal_title：Japanese journal of ophthalmology

authors： Inoue K,Kimura C,Amano S,Sato T,Fujita N,Kagaya F,Kaji Y,Tsuru T,Araie M

更新日期：2001-07-01 00:00:00

abstract：PURPOSE:To investigate various XLRS1 (RS1) gene mutations in Chinese families with X-linked juvenile retinoschisis (XLRS or RS). METHODS:Genomic DNA was isolated from leukocytes of 29 male patients with X-linked juvenile retinoschisis, 38 female carriers, and 100 normal controls. All 6 exons of the RS1 gene were ampli...

journal_title：Japanese journal of ophthalmology

authors： Ma X,Li X,Wang L

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:To investigate the role of mechanical stretch in the regulation of matrix metalloproteinase-2 (MMP-2) in scleral fibroblasts of chick embryos. METHODS:Scleral fibroblasts derived from chick embryos were seeded onto flexible bottom culture plates, and subjected to a pulsatile stretch when the cells became subco...

journal_title：Japanese journal of ophthalmology

authors： Fujikura H,Seko Y,Tokoro T,Mochizuki M,Shimokawa H

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:This study examines the impact of cataracts on health-related quality of life (HR-QOL) and health events in the older population. METHODS:The study population consisted of 439 unoperated cataract patients aged 60 years or older who visited any of the facilities affiliated with the Cataract Survey Group of the ...

journal_title：Japanese journal of ophthalmology

authors： Yamada M,Mizuno Y,Miyake Y,Cataract Survey Group of the National Hospital Organization of Japan.

更新日期：2009-09-01 00:00:00

abstract：:Purpose: Acute retinal necrosis (ARN) is caused by varicella zoster virus (VZV) infection. In this study, we investigated the activity of this virus and expressions of some cytokines.Patients and Methods: The expressionof VZV thymidine kinase and some cytokines were investigated by reverse transcriptase-polymerase cha...

journal_title：Japanese journal of ophthalmology

authors： Sato M,Abe T,Tamai M

更新日期：2000-11-01 00:00:00

abstract：PURPOSE:To measure choroidal thickness in healthy pregnant women using enhanced depth imaging optical coherence tomography (EDI-OCT) and compare the measurements with those of healthy non-pregnant women. METHODS:Choroidal thickness was measured at the fovea and at 3 mm superior, inferior, temporal, and nasal to the fo...

journal_title：Japanese journal of ophthalmology

authors： Takahashi J,Kado M,Mizumoto K,Igarashi S,Kojo T

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:We investigated the keratocyte response and stromal remodeling after corneal incision and photorefractive keratectomy to understand the histophysiological and immunohistochemical differences between these two types of surgery. METHODS:Corneal incision or photorefractive keratectomy was performed in rabbits or ...

journal_title：Japanese journal of ophthalmology

authors： Tanaka T

更新日期：2000-11-01 00:00:00

abstract：PURPOSE:To evaluate the repeatability of corneal deformation parameters measured using a dynamic Scheimpflug analyzer and the impact of baseline clinical factors on the repeatability of each parameter. STUDY DESIGN:Retrospective, cross-sectional study. METHODS:Forty-eight eyes (48 healthy subjects; mean age, 49.0 ± 1...

journal_title：Japanese journal of ophthalmology

authors： Miki A,Maeda N,Asai T,Ikuno Y,Nishida K

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To evaluate dry eye symptoms, tear film function and ocular surface changes in patients with psoriasis. METHODS:The Dry Eye Questionnaire and ophthalmic examination including the Schirmer test, tear break-up time, corneal fluorescein test, meibomian gland obstruction and conjunctival impression cytology were a...

journal_title：Japanese journal of ophthalmology

authors： Her Y,Lim JW,Han SH

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:To evaluate the effect of preservative-free (PF) tafluprost on diurnal variation of intraocular pressure (IOP) and ocular perfusion pressure (OPP), measured by use of home IOP and blood-pressure (BP) monitoring devices, for primary open angle glaucoma (POAG) patients. METHODS:Twenty-two eyes from 22 patients w...

journal_title：Japanese journal of ophthalmology

authors： Cho SY,Kim YY,Yoo C,Lee TE

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To determine the efficacy of real-time PCR for the diagnosis and prognosis of varicella-zoster virus (VZV) keratitis. STUDY DESIGN:Retrospective case series. METHODS:Patients: 545 consecutive patients with keratitis were examined to quantify copy numbers of VZV DNA by real-time PCR. Association of copy number...

journal_title：Japanese journal of ophthalmology

authors： Inata K,Miyazaki D,Uotani R,Shimizu D,Miyake A,Shimizu Y,Inoue Y

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:To examine the effectiveness, safety, and stability of laser subepithelial keratomileusis (LASEK), a modified photorefractive keratectomy for low to moderate myopia. METHODS:This study evaluated the results of LASEK in 48 myopic patients (84 eyes) with a consecutive 6-month follow-up period. Preoperative myopi...

journal_title：Japanese journal of ophthalmology

authors： Lee JB,Choe CM,Seong GJ,Gong HY,Kim EK

更新日期：2002-05-01 00:00:00

abstract：:Purpose: We have developed a new method for quantification of metamorphopsia and applied it to study distorted vision resulting from epiretinal membrane (ERM).Patients and Methods: We prepared a modified Amsler chart, which was a square grid formed by black lines on a white background with 12 cm on a side and divided ...

journal_title：Japanese journal of ophthalmology

authors： Shinoda K,Ishida S,Kawashima S,Matsuzaki T,Yamada K,Katsura H

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:To clarify the usefulness of measuring anterior chamber depth by the IOLMaster for early-stage assessment of the therapeutic effect of steroid pulse therapy in patients with Vogt-Koyanagi-Harada (VKH) syndrome with active uveitis. METHODS:Seven patients with VKH syndrome (three men and four women) participated...

journal_title：Japanese journal of ophthalmology

authors： Otsuki T,Shimizu K,Igarashi A,Kamiya K

更新日期：2010-09-01 00:00:00

abstract：:We examined ophthalmologically five affected members of a family with type IIa hyperlipoproteinemia. All of them had increased levels of cholesterol and low-density lipoprotein. Corneal arcus was found in three of the five members; a 50-year-old man, a 43-year-old woman and a 13-year-old boy. We believe that the corne...

journal_title：Japanese journal of ophthalmology

authors： Hayasaka S,Honda M,Kitaoka M,Chiba R

更新日期：1984-01-01 00:00:00