Abstract：
:Purpose: We have developed a new method for quantification of metamorphopsia and applied it to study distorted vision resulting from epiretinal membrane (ERM).Patients and Methods: We prepared a modified Amsler chart, which was a square grid formed by black lines on a white background with 12 cm on a side and divided into 2-cm quadrants. The patients were asked to trace any straight lines on the chart which appeared irregular or curved. The length of all lines traced by the patients was measured except for the outer frame. The total length of the chart itself was 1.200 mm, but it would appear longer in patients with metamorphopsia. In addition, the severity of metamorphopsia was scored subjectively as follows: 1, absent; 2, slight; 3, mild; 4, moderate; and 5, severe. The relationship of the length to the score and to the visual acuity were analysed. Sixty-three patients with unilateral ERM were examined.Results: The length of the line ranged from 1,200 to 1,259 mm (mean 1,223.3 mm) and was correlated significantly to the score. Conclusions: This method might be applied usefully in evaluating the severity of metamorphopsia and the surgical outcome of eyes with ERM.
journal_name
Jpn J Ophthalmoljournal_title
Japanese journal of ophthalmologyauthors
Shinoda K,Ishida S,Kawashima S,Matsuzaki T,Yamada K,Katsura Hdoi
10.1016/s0021-5155(00)00157-xkeywords:
subject
Has Abstractpub_date
2000-05-01 00:00:00pages
318issue
3eissn
0021-5155issn
1613-2246pii
S002151550000157Xjournal_volume
44pub_type
杂志文章abstract：BACKGROUND:In this report of two Okinawan patients with Beals syndrome and accompanying ocular complications, the symptoms of Beals syndrome and Marfan syndrome are compared. The etiology of these two syndromes is considered in relation to fibrillin. CASES:Case 1 was a 5-year-old boy who showed blue sclera and bilater...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-004-0106-7
更新日期：2004-09-01 00:00:00
abstract：:Management of intraocular tumors, specifically uveal melanoma, is a matter of controversy. The treatment of these ocular neoplasms varies from observation to enucleation, irradiation (cobalt plaque and proton-helium particle) and eye wall resection. Over the last 18 years, we have developed two techniques for surgical...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：PURPOSE:To compare the cytotoxicity of povidone-iodine solution (PVP-I) with that of polyvinyl alcohol-iodine solution (PAI) for ophthalmic use. METHODS:Cells of the human corneal epithelial cell line HCE-T were exposed to various dilutions of PVP-I or PAI, and the cytotoxicity of these two antiseptics was evaluated. ...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-014-0348-y
更新日期：2014-11-01 00:00:00
abstract：PURPOSE:Topical mitomycin C (MMC) administration is reportedly effective in treating ocular surface neoplasms such as squamous cell carcinoma. We treated a case of ocular epithelial dysplasia that had spread too diffusely to be completely removed. We examined the ultrastructure of and c-met (hepatocyte growth factor re...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(00)00270-7
更新日期：2000-11-01 00:00:00
abstract：:Prostaglandin D2 (PGD2) and 64E, a derivative of PGs, were tested for their capacity to suppress the growth of retinoblastoma in the nude mouse. Ten million cells of an established cell line of human retinoblastoma, Y-79 cells, were transferred subcutaneously into the nude mouse, and after the transferred cells became...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：PURPOSE:To identify a mutation in the PRPF31 gene in a family (Family K) with autosomal dominant retinitis pigmentosa (adRP) linked to 19q13.4 (RP11) and to find the frequency of mutations in the PRPF31 gene among Japanese families with adRP. METHODS:Genomic DNA specimens were prepared from five symptomatic and two as...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-006-0394-1
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:To determine the association of age-related maculopathy susceptibility 2 (ARMS2) gene polymorphisms with the 12-month outcomes of intravitreal aflibercept combined with photodynamic therapy (IVA+PDT) in polypoidal choroidal vasculopathy (PCV). STUDY DESIGN:Interventional cohort study. METHODS:This was a retro...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-019-00683-6
更新日期：2019-09-01 00:00:00
abstract：PURPOSE:To compare the progression of posterior vitreous detachment (PVD) during aging among eyes of diabetics with diabetic retinopathy (DR), eyes of diabetics without DR, and eyes of nondiabetics. STUDY DESIGN:Prospective cross-sectional study. METHODS:One-hundred thirty-three diabetic eyes with DR (DR group), 254 ...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-020-00720-9
更新日期：2020-03-01 00:00:00
abstract：:Spontaneous retinal degeneration of Celestial goldfish was studied histologically and electrophysiologically. Retinal degeneration was divided into three stages. Until the age of 75 days (Stage 0) the retina showed normal histological development and the electroretinograms (ERGs) exhibited dominant b-waves similar to ...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:Purpose: Acute retinal necrosis (ARN) is caused by varicella zoster virus (VZV) infection. In this study, we investigated the activity of this virus and expressions of some cytokines.Patients and Methods: The expressionof VZV thymidine kinase and some cytokines were investigated by reverse transcriptase-polymerase cha...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(00)00254-9
更新日期：2000-11-01 00:00:00
abstract：BACKGROUND:Interferon alpha-2b (IFN alpha 2b) was recently shown to be effective as an alternative therapy for conjunctival intraepithelial neoplasia (CIN). Herein, we report our successful management of CIN by the use of IFN alpha 2b. CASE:A 73-year-old woman presented with a complaint of irritation due to a tumorous...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(01)00494-4
更新日期：2002-03-01 00:00:00
abstract：PURPOSE:To examine the effectiveness, safety, and stability of laser subepithelial keratomileusis (LASEK), a modified photorefractive keratectomy for low to moderate myopia. METHODS:This study evaluated the results of LASEK in 48 myopic patients (84 eyes) with a consecutive 6-month follow-up period. Preoperative myopi...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(02)00473-2
更新日期：2002-05-01 00:00:00
abstract：PURPOSE:To evaluate the effectiveness of the isolated caruncular approach to orbital decompression of thyroid ophthalmopathy. METHODS:In a retrospective, noncomparative, interventional case series, we reviewed the records of 29 patients (48 orbits) who had thyroid ophthalmopathy and had undergone orbital decompression...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-004-0073-z
更新日期：2004-07-01 00:00:00
abstract：:A computerized digital image analysis system was developed to evaluate the retinal nerve fiber layer (RNFL) by red-free fundus photography. The image intensity of the RNFL was computed for 30 degrees between the disc and macula. Thirty early open-angle glaucoma patients and 30 normal age-matched subjects were examined...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy and safety of intravitreal drug injections using a short 34-gauge needle. STUDY DESIGN:Retrospective study. METHODS:This study included patients with age-related macular degeneration, diabetic macular edema, or macular edema associated with retinal vein occlusion. We reviewed the medi...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-019-00663-w
更新日期：2019-05-01 00:00:00
abstract：PURPOSE:To determine the pharmacological response when dysiherbaine acts on cultured Müller cells, considering the glutamate receptor functions. Dysiherbaine is a new excitotoxic amino acid, which was recently isolated from the liquid extract of a certain sponge. METHODS:Retinas of adult rabbits were used to culture t...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(01)00488-9
更新日期：2002-03-01 00:00:00
abstract：PURPOSE:Sweet's syndrome (SS) is a skin disorder clinically characterized by fever, neutrophilia, and painful edematous plaques that occasionally causes posterior uveitis. We present two cases of SS with panuveitis resembling Behçet's disease (BD). SUBJECTS:Two patients with panuveitis associated with SS. OBSERVATION...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-012-0129-4
更新日期：2012-05-01 00:00:00
abstract：PURPOSE:To investigate the differences in thickness and depth of the lamina cribrosa (LC) between ocular hypertension (OH) patients and normal control subjects, using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (SD-OCT). METHODS:EDI-OCT data were obtained from the subjects in a cross-sect...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-015-0407-z
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:To investigate gelatinase [matrix metalloproteinase (MMP)-2 and MMP-9] expression in the tear fluid of patients with recurrent corneal erosion (RCE). METHODS:Eleven patients with RCE, three patients with traumatic corneal erosion, and 10 control individuals were enrolled in this study. Tear samples from RCE ey...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-007-0455-0
更新日期：2007-09-01 00:00:00
abstract：:Localization of carbonic anhydrase (CA) was investigated in the rat eye by light and electron microscopy, and the inhibitory effects on CA distribution in the rat eye were compared between dorzolamide and acetazolamide. The cobalt sulfide histochemical method was used to study the CA localization. Acidic osmification ...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:We investigated the keratocyte response and stromal remodeling after corneal incision and photorefractive keratectomy to understand the histophysiological and immunohistochemical differences between these two types of surgery. METHODS:Corneal incision or photorefractive keratectomy was performed in rabbits or ...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(00)00269-0
更新日期：2000-11-01 00:00:00
abstract：PURPOSE:We investigated the efficacy of the tear sampling method using a filter paper to evaluate eosinophil cationic protein (ECP) levels in patients with allergic disorders. METHODS:Subjects were an allergic group comprising patients with allergic conjunctivitis, vernal keratoconjunctivitis, or atopic keratoconjunct...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(02)00630-5
更新日期：2003-01-01 00:00:00
abstract：PURPOSE:To shorten the duration of prone positioning after macular hole surgery from 1 week to 1 day, and to evaluate preoperative factors and the initial hole closure rate. METHODS:The subjects were 33 patients (34 eyes) who underwent macular hole surgery between April 1998 and August 1999, and maintained the prone p...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(01)00468-3
更新日期：2002-01-01 00:00:00
abstract：PURPOSE:Changes in optic disc and peripapillary structures associated with optic nerve edema in idiopathic intracranial hypertension (IIH), can be evaluated with spectral domain optical coherence tomography (SD-OCT). We aimed to evaluate the association between increased cerebrospinal fluid (CSF) opening pressure and c...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-020-00807-3
更新日期：2021-01-09 00:00:00
abstract：PURPOSE:The aim of this study was to clarify the demographics, clinical features, and outcomes of Japanese patients with sebaceous carcinoma of the eyelid or conjunctiva. STUDY DESIGN:Retrospective study. METHODS:One hundred twenty-five patients with sebaceous carcinoma of the eyelid or conjunctiva diagnosed at Tokyo...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-020-00756-x
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:To evaluate the cycloplegic effect of mixed eye drops containing 0.5% tropicamide and 0.5% phenylephrine in myopic children, and to determine whether their efficacy was associated with their clinical characteristics. METHODS:Eighty-one myopic children (age, mean +/- SD, 11.0 +/- 1.5 years; mean spherical equiv...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-006-0400-7
更新日期：2007-03-01 00:00:00
abstract：PURPOSE:To determine whether the single-flash electroretinogram (ERG) can predict the postoperative outcome in diabetic cases where massive vitreous hemorrhage precludes fundus observation. METHODS:Eighty-five diabetic patients (105 eyes) who underwent vitrectomy due to dense vitreous hemorrhage were studied retrospec...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(03)00015-7
更新日期：2003-05-01 00:00:00
abstract：PURPOSE:The aims of the study were to detect early changes in the optic nerve function of patients with Graves' orbitopathy (GrO) who do not have any signs and symptoms of optic neuropathy, using pattern visual evoked potentials (P-VEP), and investigate any possible relation between the disease activity and P-VEP P100 ...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(03)00101-1
更新日期：2003-09-01 00:00:00
abstract：PURPOSE:Lysophosphatidic acid (LPA), which activates the small guanosine triphosphate (GTP)-binding protein Rho, was previously shown to promote migration of the rabbit corneal epithelium in culture. The signaling pathway responsible for this effect of LPA was examined in this study with a human corneal epithelial (HCE...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-003-0059-2
更新日期：2004-05-01 00:00:00
abstract：PURPOSE:To investigate global protein expression profiles in the retinas of normal and glucocorticoid-induced ocular hypertensive rats by proteomic analysis. METHODS:Ocular hypertension was induced by topical application of dexamethasone (DEX) for 4 weeks. Age-matched untreated rats served as controls. Intraocular pre...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-007-0507-5
更新日期：2008-03-01 00:00:00
