Mutation c. 1142 del G in the PRPF31 gene in a family with autosomal dominant retinitis pigmentosa (RP11) and its implications.

abstract：:A 76-year-old Japanese woman had suffered from fatigue, weight loss, and cutaneous hyperpigmentation at the age of 38 years and was diagnosed as having tuberculous Addison's disease. Since then, corticosteroids had been administered effectively as hormonal replacement. At the age of 75 years, the patient presented wit...

journal_title：Japanese journal of ophthalmology

authors： Kakiuchi T,Uehara F,Ohba N

更新日期：1998-09-01 00:00:00

abstract：PURPOSE:We report here a patient with bilateral papillomacular retinoschisis with an enlarged glaucomatous optic nerve head cup and a focal lamina cribrosa defect, the findings of our clinical investigations of this case, and the chosen treatment and outcome. DESIGN:This is an observational case report. METHODS:Clini...

journal_title：Japanese journal of ophthalmology

authors： Yoshitake T,Nakanishi H,Setoguchi Y,Kuroda K,Amemiya K,Taniguchi M,Otani A

更新日期：2014-09-01 00:00:00

abstract：:We studied the inhibitory effects of chicken egg white ovomacroglobulin, a broad-spectrum protease inhibitor, and a synthetic protease inhibitory peptide, Bz-GFR-O-mercaptoanilide, on the growth of two strains of Serratia marcescens in a synthetic medium. The growth of the virulent protease-producing strain, S. marces...

journal_title：Japanese journal of ophthalmology

authors： Miyagawa S,Matsumoto K,Kamata R,Okamura R,Maeda H

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:To compare endothelial damage of the donor cornea in relation to the method of inserting the donor cornea into the recipient anterior chamber during Descemet-stripping automated endothelial keratoplasty (DSAEK). METHODS:Fifteen enucleated pig eyes were used. The donor corneoscleral buttons were mounted in an a...

journal_title：Japanese journal of ophthalmology

authors： Hwang H,Kim M

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:To establish a rat glaucoma model with chronic intraocular pressure (IOP) elevation induced by microbeads suspended in sodium sulfate-sodium hyaluronate. METHODS:Chronic elevation of IOP was induced unilaterally by injecting polystyrene microbeads, suspended in 4 % sodium sulfate and 3 % sodium hyaluronate, in...

journal_title：Japanese journal of ophthalmology

authors： Matsumoto Y,Kanamori A,Nakamura M,Negi A

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:To investigate cytokine mRNA expression during the inflammatory process induced in the contralateral eyes by uniocular inoculation of herpes simplex virus type 1 (HSV-1) via the anterior chamber. METHODS:BALB/c mice were inoculated in the anterior chamber with 5 x 10(4) plaque-forming units of HSV-1 (KOS). mRN...

journal_title：Japanese journal of ophthalmology

authors： Saitoh-Ishibashi K,Ishibashi K,Azumi A,Negi A

更新日期：2003-03-01 00:00:00

abstract：:The purpose of this study is to elucidate the extension of the corneal endothelium onto the iris surface, a condition which has been found in the eyes with rubeosis iridis in various ocular disorders. Histopathology of the anterior chamber angle was studied by electron microscopy in 6 eyes with neovascular glaucoma oc...

journal_title：Japanese journal of ophthalmology

authors： Nomura T

更新日期：1983-01-01 00:00:00

abstract：:Persistent bullous keratopathy was produced in one eye of a rabbit by anterior chamber irrigation with benzalkonium chloride solution (BAK). Corneal grafts were made from both eyes of another rabbit and they were transplanted to the eye with bullous keratopathy and the normal fellow eye, which served as the control. S...

journal_title：Japanese journal of ophthalmology

authors： Yang HJ,Sato T,Matsubara M,Tanishima T

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To evaluate macular shape in normal eyes using swept-source optical coherence tomography (SS-OCT). STUDY DESIGN:Retrospective cross-sectional study. METHODS:We retrospectively evaluated 77 normal eyes of 48 subjects. Curvature of retinal pitment epithelium (RPE) and choroid/scleral interface (CSI) was measure...

journal_title：Japanese journal of ophthalmology

authors： Minami S,Ito Y,Ueno S,Kataoka K,Takeuchi J,Ito H,Nakano Y,Kitagawa M,Leahy C,Straub J,Terasaki H

更新日期：2020-03-01 00:00:00

abstract：:The effect of pertussis toxin (PT) on experimental autoimmune uveoretinitis (EAU) induced by immunization with S-antigen was examined in rats. Intravenous administration of PT (2 micrograms/rat) initiated the development of EAU in rats that had been made resistant to the induction of EAU by immunization with S-antigen...

journal_title：Japanese journal of ophthalmology

authors： Suzuki I,Takahashi S,Fujii Y,Fuyama S,Arai S

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:To elucidate the characterization of intraocular pressure (IOP) spike after trabeculotomy, and after the combined procedure of phacoemulsification and aspiration (PEA) and intraocular lens (IOL) implantation. METHODS:Included in this study were 39 patients (53 eyes) with primary open-angle glaucoma with IOPs u...

journal_title：Japanese journal of ophthalmology

authors： Inatani M,Tanihara H,Muto T,Honjo M,Okazaki K,Kido N,Honda Y

更新日期：2001-05-01 00:00:00

abstract：:An 18-year-old Japanese boy with optic disk drusen associated with left central retinal artery occlusion was reported. Transient central blurred vision, possibly caused by central retinal artery spasm, was noticed as an initial symptom of optic disk drusen in the left eye. Prolonged and repeated spasm might have given...

journal_title：Japanese journal of ophthalmology

authors： Uehara M,Inomata H,Yamana Y,Taniguchi Y,Tsuji K

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:To identify the cross-sectional characteristics of filtering blebs associated with intraocular pressure (IOP) control at 1 year after trabeculectomy with a square scleral flap and a fornix-based conjunctival flap. METHODS:A retrospective consecutive case series study was conducted. Eighty-four eyes of 79 patie...

journal_title：Japanese journal of ophthalmology

authors： Narita A,Morizane Y,Miyake T,Seguchi J,Baba T,Shiraga F

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:To measure changes in choroidal thickness (CT), retinal thickness (RT), and axial length (AL) accompanying intraocular pressure (IOP) increase and to investigate the changes in axial eye dimensions induced by IOP increase. METHODS:Thirty-four eyes of 34 patients undergoing a diagnostic provocative test for pri...

journal_title：Japanese journal of ophthalmology

authors： Hata M,Hirose F,Oishi A,Hirami Y,Kurimoto Y

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:From an early stage, retinitis pigmentosa (RP) patients suffer from night blindness which causes nocturnal mobility difficulties. We created a wearable visual aid that uses a high-performance see-through display, and added a high-sensitivity camera with a complementary metal-oxide-semiconductor sensor. Here, we...

journal_title：Japanese journal of ophthalmology

authors： Ikeda Y,Nakatake S,Funatsu J,Fujiwara K,Tachibana T,Murakami Y,Hisatomi T,Yoshida S,Enaida H,Ishibashi T,Sonoda KH

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:Defensins are antimicrobial peptides and are classified into three groups, alpha-, beta- and theta-defensins. We investigated the localization of human neutrophil peptides (HNP) 1-3, which are members of the alpha-defensin subfamily, and the expression of human beta-defensin 1 (hBD-1) and hBD-2 in the ocular su...

journal_title：Japanese journal of ophthalmology

authors： Ikeda A,Sakimoto T,Shoji J,Sawa M

更新日期：2005-03-01 00:00:00

abstract：:Three cases of medullated nerve fibers of the retina were seen. They had medullated nerve fibers in both the upper and lower quadrants of the temporal retina, whereby the temporal raphe of the retinal nerve fiber layer could be visualized. Some nerve fibers from the upper and lower quadrants crossed each other on the ...

journal_title：Japanese journal of ophthalmology

authors： Sakai T,Sano K,Tsuzuki K,Ueno M,Kawamura Y

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:To evaluate the cycloplegic effect of mixed eye drops containing 0.5% tropicamide and 0.5% phenylephrine in myopic children, and to determine whether their efficacy was associated with their clinical characteristics. METHODS:Eighty-one myopic children (age, mean +/- SD, 11.0 +/- 1.5 years; mean spherical equiv...

journal_title：Japanese journal of ophthalmology

authors： Hamasaki I,Hasebe S,Kimura S,Miyata M,Ohtsuki H

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:In this report of two Okinawan patients with Beals syndrome and accompanying ocular complications, the symptoms of Beals syndrome and Marfan syndrome are compared. The etiology of these two syndromes is considered in relation to fibrillin. CASES:Case 1 was a 5-year-old boy who showed blue sclera and bilater...

journal_title：Japanese journal of ophthalmology

authors： Takaesu-Miyagi S,Sakai H,Shiroma T,Hayakawa K,Funakoshi Y,Sawaguchi S

更新日期：2004-09-01 00:00:00

abstract：PURPOSE:To evaluate the functional surgical success, complications, and degree of satisfaction after endoscopy-guided transcaruncular Jones tube intubation without dacryocystorhinostomy (DCR). METHODS:A pair of Westcott scissors was passed into the nose from the side of the caruncle, and the lacrimal bone was penetrat...

journal_title：Japanese journal of ophthalmology

authors： Choi WC,Yang SW

更新日期：2006-03-01 00:00:00

abstract：PURPOSE:To evaluate the relationship between visual disability and visual scores in patients with retinitis pigmentosa. METHODS:The relationship between visual disability and visual scores (visual acuity and visual field) was investigated in 93 patients with retinitis pigmentosa. The visual disability of each patient ...

journal_title：Japanese journal of ophthalmology

authors： Sumi I,Matsumoto S,Okajima O,Shirato S

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:To investigate the frequency of infraorbital nerve enlargement (IONE) in orbital lymphoproliferative disorders, and to show that IONE can contribute to the clinical diagnosis of IgG4-related orbital diseases (IgG4-ROD). SUBJECTS AND METHODS:71 cases in which orbital lymphoproliferative disorders were diagnosed...

journal_title：Japanese journal of ophthalmology

authors： Ohshima K,Sogabe Y,Sato Y

更新日期：2012-07-01 00:00:00

abstract：:The spectral sensitivity of the ERG c-wave was studied in the chicken under yellow or red light adaptation of various intensities, ie, 1, 3, 4 and 5 W/m2 at the corneal surface in the former, and 3, 4 and 5 W/m2 in the latter. The peak wavelength of the spectral sensitivity curve of the c-wave amplitude under both yel...

journal_title：Japanese journal of ophthalmology

authors： Takahashi K,Fukuda A,Mori T,Takahashi Y,Onoe S,Yoshimura Y,Tazawa Y

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:To evaluate the changes in aqueous flare in psoriasis patients and to identify the factors that influence the level of aqueous flare. METHODS:We examined the 68 eyes of 34 psoriasis patients and the 68 eyes of 34 healthy subjects with a laser flare-cell meter. Complete dermatologic and ophthalmic examinations ...

journal_title：Japanese journal of ophthalmology

authors： Okamoto F,Umebayasi Y,Ohtsuka F,Hommura S

更新日期：2001-03-01 00:00:00

abstract：:The effects of four commercially available irrigating solutions on the spreading of rabbit corneal endothelial cells on various extracellular matrices were studied. Cultured rabbit corneal endothelial cells, suspended in one of the following intraocular irrigating solutions, Opeguard MA, BSS, BSS Plus, lactated Ringer...

journal_title：Japanese journal of ophthalmology

authors： Nishida T,Otori T

更新日期：1991-01-01 00:00:00

abstract：:Single fiber electromyography (SFEMG) was carried out in the extraocular muscles (EOMs) of 40 adult cats, and the recordings were analyzed. The small fluctuations of the interpotential interval (IPI), so-called "jitter phenomenon", were represented quantitatively as a mean consecutive difference (MCD). The MCD and the...

journal_title：Japanese journal of ophthalmology

authors： Hattori M,Mimura O,Haruta R,Uyama J,Shimo-Oku M

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:The aims of the study were to detect early changes in the optic nerve function of patients with Graves' orbitopathy (GrO) who do not have any signs and symptoms of optic neuropathy, using pattern visual evoked potentials (P-VEP), and investigate any possible relation between the disease activity and P-VEP P100 ...

journal_title：Japanese journal of ophthalmology

authors： Acaroğlu G,Simşek T,Ozalp S,Mutluay A

更新日期：2003-09-01 00:00:00

abstract：PURPOSE:To evaluate the effect of tetramethylpyrazine on the elevation of aqueous flare and intraocular pressure (IOP) induced by prostaglandin (PG) E(2) and PGE(2) receptor (EP) agonists. METHODS:PGE(2) or EP agonists (11-deoxy PGE(1), EP(2) agonist; 17-phenyl trinor PGE(2), EP(1) and EP(3) agonist; or sulprostone, E...

journal_title：Japanese journal of ophthalmology

authors： Kitagawa K,Hayasaka S,Nagaki Y,Watanabe K

更新日期：2001-05-01 00:00:00

abstract：PURPOSE:To investigate gelatinase [matrix metalloproteinase (MMP)-2 and MMP-9] expression in the tear fluid of patients with recurrent corneal erosion (RCE). METHODS:Eleven patients with RCE, three patients with traumatic corneal erosion, and 10 control individuals were enrolled in this study. Tear samples from RCE ey...

journal_title：Japanese journal of ophthalmology

authors： Sakimoto T,Shoji J,Yamada A,Sawa M

更新日期：2007-09-01 00:00:00

abstract：:Purpose: A young patient of ophthalmoplegic migraine with recurrent oculomotor nerve palsy is reported.Case: A 4-year-old girl came to our hospital complaining of recurrent left ptosis and double vision which completely resolved within a few days. She had a history of drowsiness after vomiting every two months. Left o...

journal_title：Japanese journal of ophthalmology

authors： Ishikawa H,Yoshihara M,Mizuki K,Kashima Y

更新日期：2000-09-01 00:00:00