当前位置： SCI文献检索 > JAPANESE JOURNAL OF OPHTHALMOLOGY期刊下所有文献 > Upregulation of matrix metalloproteinase in tear fluid of patients with recurrent corneal erosion.

Upregulation of matrix metalloproteinase in tear fluid of patients with recurrent corneal erosion.

Abstract：

PURPOSE:To investigate gelatinase [matrix metalloproteinase (MMP)-2 and MMP-9] expression in the tear fluid of patients with recurrent corneal erosion (RCE). METHODS:Eleven patients with RCE, three patients with traumatic corneal erosion, and 10 control individuals were enrolled in this study. Tear samples from RCE eyes were obtained once, either at the time of recurrence (onset-phase samples, seven samples), or during the remission period (remission-phase samples, four samples). Tear samples from the nonaffected fellow eyes of the RCE patients were also examined once (fellow-eye samples, ten samples from ten patients). In addition, three samples from three patients with traumatic corneal erosion and ten samples from ten control individuals were obtained as well. Tear samples were collected by a modified Schirmer test I method and analyzed by gelatin zymography. RESULTS:Neither the active form of MMP-2 nor that of MMP-9 was detected in the samples from traumatic corneal erosion patients and control individuals. Both active MMP-2 and active MMP-9 were detected in all seven onset-phase samples. Active MMP-2 and active MMP-9 were detected in three of the four remission-phase samples. Although none of the ten fellow eyes had a history of RCE, active MMP-2 and active MMP-9 were detected in three fellow-eye samples. CONCLUSIONS:Gelatinase expression was upregulated in the tear fluid of RCE patients. The presence of gelatinase in the affected eye during the remission phase as well as in the nonaffected fellow eye indicates that gelatinase expression in the tear fluid may be related to the recurrence of corneal erosion.

journal_name

Jpn J Ophthalmol

journal_title

Japanese journal of ophthalmology

authors

Sakimoto T,Shoji J,Yamada A,Sawa M

doi

10.1007/s10384-007-0455-0

subject

Has Abstract

pub_date

2007-09-01 00:00:00

pages

343-346

issue

5

eissn

0021-5155

issn

1613-2246

pii

10.1007/s10384-007-0455-0

journal_volume

51

pub_type

杂志文章

相关文献

JAPANESE JOURNAL OF OPHTHALMOLOGY文献大全
  • Single fiber electromyography in cat extraocular muscles.

    abstract：:Single fiber electromyography (SFEMG) was carried out in the extraocular muscles (EOMs) of 40 adult cats, and the recordings were analyzed. The small fluctuations of the interpotential interval (IPI), so-called "jitter phenomenon", were represented quantitatively as a mean consecutive difference (MCD). The MCD and the...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Hattori M,Mimura O,Haruta R,Uyama J,Shimo-Oku M

    更新日期：1986-01-01 00:00:00

  • Herpetic epithelial keratitis caused by acyclovir-resistant strain.

    abstract：:Dendritic keratitis occurred during oral acyclovir (ACV) therapy in a 60-year-old man. Corneal stromal edema and iritis were found at his first visit. Herpetic keratouveitis was suspected, based on clinical findings and previous history. Treatment with steroid eyedrops and ACV ointment was initiated. However, ACV [cor...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Mori Y,Inoue Y,Shimomura Y

    更新日期：1994-01-01 00:00:00

  • Evaluation of corneal damage caused by iodine preparations using human corneal epithelial cells.

    abstract：PURPOSE:To compare the cytotoxicity of povidone-iodine solution (PVP-I) with that of polyvinyl alcohol-iodine solution (PAI) for ophthalmic use. METHODS:Cells of the human corneal epithelial cell line HCE-T were exposed to various dilutions of PVP-I or PAI, and the cytotoxicity of these two antiseptics was evaluated. ...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-014-0348-y

    authors： Shibata Y,Tanaka Y,Tomita T,Taogoshi T,Kimura Y,Chikama T,Kihira K

    更新日期：2014-11-01 00:00:00

  • A 10-year review of penetrating keratoplasty.

    abstract：PURPOSE:To survey the changes in indications for penetrating keratoplasty (PKP) and re-evaluate the risk factors for allograft rejection and graft failure. METHODS:We evaluated the records of 396 eyes of 335 patients who had undergone PKP at the Tokyo University Hospital between 1987 and 1997. Clinical results were an...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0021-5155(99)00190-2

    authors： Inoue K,Amano S,Oshika T,Sawa M,Tsuru T

    更新日期：2000-03-01 00:00:00

  • Effects of local hypothermia on ischemic eyes in vitrectomy.

    abstract：:The effects of local hypothermia on postoperative inflammation, electroretinogram (ERG) and histological changes of the retina were evaluated in experimental vitrectomy in pressure-induced ischemic rabbit eyes. The solutions used for intraocular perfusion were maintained at 8 degrees C, 22 degrees C or 38 degrees C. F...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Tamai K,Toumoto E

    更新日期：1996-01-01 00:00:00

  • Endoscopy-guided transcaruncular Jones tube intubation without dacryocystorhinostomy.

    abstract：PURPOSE:To evaluate the functional surgical success, complications, and degree of satisfaction after endoscopy-guided transcaruncular Jones tube intubation without dacryocystorhinostomy (DCR). METHODS:A pair of Westcott scissors was passed into the nose from the side of the caruncle, and the lacrimal bone was penetrat...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-005-0284-y

    authors： Choi WC,Yang SW

    更新日期：2006-03-01 00:00:00

  • Detection of HIV-RNA in aqueous humor and subretinal fluid in an HIV carrier with rhegmatogenous retinal detachment.

    abstract：BACKGROUND:Although human immunodeficiency virus (HIV)-related ocular complexes are commonly observed in acquired immune deficiency syndrome (AIDS) patients, it has not been previously reported that HIV had already invaded the ocular tissues of HIV carriers. CASE:A 56-year-old woman was diagnosed as having rhegmatogen...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0021-5155(00)00278-1

    authors： Kashiwagi K,Gohdo T,Sato S,Iijima H,Tsukahara S

    更新日期：2000-11-01 00:00:00

  • A comparative study of latanoprost (Xalatan) and isopropyl unoprostone (Rescula) in normal and glaucomatous monkey eyes.

    abstract：:Latanoprost (PhXA41, Xalatan) and isopropyl unoprostone (UF-021, unoprostone, Rescula) two new prostanoid derivatives, have been shown to reduce intraocular pressure (IOP) significantly in patients with glaucoma or ocular hypertension. This study was designed to compare the ocular hypotensive effects of latanoprost an...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0021-5155(97)00128-7

    authors： Serle JB,Podos SM,Kitazawa Y,Wang RF

    更新日期：1998-03-01 00:00:00

  • Safety of retrocorneal plaque aspiration for managing fungal keratitis.

    abstract：PURPOSE:To evaluate the safety of retrocorneal plaque aspiration in patients with fungal keratitis. STUDY DESIGN:Retrospective study. METHODS:A retrospective case series of fungal keratitis seen at Kyoto Prefectural University of Medicine between November 2013 and September 2018. Patients with retrocorneal plaque who...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-020-00718-3

    authors： Kitazawa K,Fukuoka H,Inatomi T,Aziza Y,Kinoshita S,Sotozono C

    更新日期：2020-03-01 00:00:00

  • Changes in choroidal thickness and optical axial length accompanying intraocular pressure increase.

    abstract：PURPOSE:To measure changes in choroidal thickness (CT), retinal thickness (RT), and axial length (AL) accompanying intraocular pressure (IOP) increase and to investigate the changes in axial eye dimensions induced by IOP increase. METHODS:Thirty-four eyes of 34 patients undergoing a diagnostic provocative test for pri...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-012-0173-0

    authors： Hata M,Hirose F,Oishi A,Hirami Y,Kurimoto Y

    更新日期：2012-11-01 00:00:00

  • Immunohistochemical proof of intraneural localization of herpes simplex virus in experimental retinitis.

    abstract：:A unilateral intravitreal inoculation of herpes simplex virus type 1 (HSV-1) induced bilateral retinitis and encephalitis in the rat. Immunohistochemistry was employed to clarify the pathway of transmission of HSV-1 from the inoculated eye to the contralateral eye, and to identify localization of the viral antigen in ...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Matsushima M,Uyama M,Ohyama A,Ueyama T,Sugimoto T

    更新日期：1995-01-01 00:00:00

  • Morphological observations of rat corneal endothelial cells after exposure to ozonated solution.

    abstract：PURPOSE:To determine whether exposure to ozonated solution alters the morphology of corneal endothelial cells in rats and to examine the protective effect of ascorbic acid. METHODS:The anterior chambers of rat eyes were filled with 4 ppm of ozonated solution. Some were left in that state, while others were flushed out...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-008-0629-4

    authors： Suzuki H,Sato S,Murano N,Matsui H,Oharazawa H,Takahashi H

    更新日期：2009-03-01 00:00:00

  • Changes in conjunctival-scleral thickness after strabismus surgery measured with anterior segment optical coherence tomography.

    abstract：PURPOSE:To evaluate changes in conjunctival-scleral thickness following strabismus surgery with anterior segment optical coherence tomography (AS-OCT). STUDY DESIGN:Prospective, observational, consecutive case series. METHODS:Distances between the conjunctival epithelium and inner scleral wall were measured with AS-O...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-018-0609-2

    authors： Suzuki H,Hikoya A,Komori M,Inagaki R,Haseoka T,Arai S,Takagi Y,Hotta Y,Sato M

    更新日期：2018-09-01 00:00:00

  • A case of Vogt-Koyanagi-Harada disease with good visual acuity in spite of subfoveal fold.

    abstract：BACKGROUND:Vogt-Koyanagi-Harada (VKH) disease patients with the complication of subretinal pigmented proliferative tissue tend to have a poor visual prognosis. CASE:We herein report a case of VKH with good visual acuity despite a prominent subretinal fold. OBSERVATIONS:A 24-year-old woman, who experienced several rec...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0021-5155(03)00146-1

    authors： Noda Y,Sonoda KH,Nakamura T,Kawano YI,Ishibashi T,Inomata H

    更新日期：2003-11-01 00:00:00

  • Agreement between peripheral anterior chamber depth evaluation using the van Herick technique and angle width evaluation using the Shaffer system in Japanese.

    abstract：PURPOSE:To examine the correlation between the van Herick system and the Shaffer system in a large-scale epidemiological survey conducted on healthy Japanese subjects. METHODS:The van Herick technique was performed on 14,779 subjects aged 40 years and over who participated in an ophthalmic epidemiological survey condu...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-004-0169-5

    authors： Kashiwagi K,Tokunaga T,Iwase A,Yamamoto T,Tsukahara S

    更新日期：2005-03-01 00:00:00

  • Night-vision aid using see-through display for patients with retinitis pigmentosa.

    abstract：PURPOSE:From an early stage, retinitis pigmentosa (RP) patients suffer from night blindness which causes nocturnal mobility difficulties. We created a wearable visual aid that uses a high-performance see-through display, and added a high-sensitivity camera with a complementary metal-oxide-semiconductor sensor. Here, we...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-018-00644-5

    authors： Ikeda Y,Nakatake S,Funatsu J,Fujiwara K,Tachibana T,Murakami Y,Hisatomi T,Yoshida S,Enaida H,Ishibashi T,Sonoda KH

    更新日期：2019-03-01 00:00:00

  • Pharmacological dissection of multifocal electroretinograms of rabbits with Pro347Leu rhodopsin mutation.

    abstract：PURPOSE:To determine whether photoreceptor degeneration in transgenic (Tg) rabbits carrying the Pro347Leu rhodopsin mutation alters the neural activity of the middle and inner retinal neurons. METHODS:Multifocal electroretinograms (mfERGs) were recorded from eight 12-week-old Tg rabbits both before and after intravitr...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-010-0842-9

    authors： Yokoyama D,Machida S,Kondo M,Terasaki H,Nishimura T,Kurosaka D

    更新日期：2010-09-01 00:00:00

  • Effects of intraocular irrigating solutions on the spreading of rabbit corneal endothelial cells on extracellular matrices.

    abstract：:The effects of four commercially available irrigating solutions on the spreading of rabbit corneal endothelial cells on various extracellular matrices were studied. Cultured rabbit corneal endothelial cells, suspended in one of the following intraocular irrigating solutions, Opeguard MA, BSS, BSS Plus, lactated Ringer...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Nishida T,Otori T

    更新日期：1991-01-01 00:00:00

  • Disturbance of electrolyte balance in vitreous of chicks with form-deprivation myopia.

    abstract：PURPOSE:To investigate the changes in the electrolyte and protein concentrations in the vitreous of 3-week-old chicks with form-deprivation myopia (FDM). METHODS:FDM was induced in 2-day-old male white leghorn chicks by covering the left eye with a translucent plastic goggle and leaving the right eye uncovered to serv...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0021-5155(99)00177-x

    authors： Seko Y,Shimokawa H,Pang J,Tokoro T

    更新日期：2000-01-01 00:00:00

  • Ocular toxocariasis in Korea.

    abstract：PURPOSE:To analyze the characteristics and clinical manifestations of clinically diagnosed and serologically confirmed ocular toxocariasis in patients. METHODS:Thirty-three eyes of 33 patients diagnosed as having ocular toxocariasis at the Hallym University Medical Center between January 1999 and December 2008 were in...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-010-0909-7

    authors： Kwon SI,Lee JP,Park SP,Lee EK,Huh S,Park IW

    更新日期：2011-03-01 00:00:00

  • Explant culture of human lens epithelial cells from senile cataract patients.

    abstract：:Human lens epithelial cells (HLECs) with lens capsules were cultured to investigate the morphology and outgrowth potential of the cultured cells. Anterior lens capsules obtained during cataract surgery were placed cell side down in a medium in culture wells. Cultivation was successful with 24 of 36 specimens from seni...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Ibaraki N,Ohara K,Shimizu H

    更新日期：1993-01-01 00:00:00

  • New wound-healing model using cultured corneal endothelial cells. 1. Quantitative study of healing process.

    abstract：:A new in vitro model to evaluate the corneal endothelial wound-healing process was developed. Confluent monolayer cell sheets of either rabbit or bovine corneal endothelial cells were cultured on cover slips, the surface of which had been precoated with hydroxyethyl methacrylate (HEMA) except for the 8 mm-diameter are...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Miyata K,Murao M,Sawa M,Tanishima T

    更新日期：1990-01-01 00:00:00

  • Evaluating human and automated interpretation of visual field data in perimetry.

    abstract：:The complexity of visual field result evaluation has increased with the advent of automated perimetry. This in turn makes software assistance such as provided by the new Octosmart program interesting and desirable. Its accuracy and reliability in visual field evaluation must be tested, though, and the testing methodol...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Hirsbrunner HP,Fankhauser F,Funkhouser AT,Jenni A

    更新日期：1990-01-01 00:00:00

  • Visualization of microaneurysms using optical coherence tomography angiography: comparison of OCTA en face, OCT B-scan, OCT en face, FA, and IA images.

    abstract：PURPOSE:To compare the visualization of microaneurysms (MAs) in patients with diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA) with that using fluorescein angiography (FA). STUDY DESIGN:Prospective, clinical, and experimental. METHODS:This study was a prospective evaluation of imaging t...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-018-0570-0

    authors： Hamada M,Ohkoshi K,Inagaki K,Ebihara N,Murakami A

    更新日期：2018-03-01 00:00:00

  • Localization of S-antigen under various conditions of light or dark adaptation in the rabbit.

    abstract：:The localization of the S-antigen was studied by electron microscopy in the rabbit eye, under three conditions of adaptation: A) 24-hour dark adaptation, B) 24-hour dark adaptation and 1.5-hour light adaptation and C) light adaptation for 30 hours. The Fab' fraction of the IgG of rabbit against the swine S-antigen was...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Yajima S,Hasemi M,Usui M

    更新日期：1985-01-01 00:00:00

  • Vascular reactivities of isolated and perfused human ciliary arteries.

    abstract：:The vascular responses to 8 agents, norepinephrine (NE), phenylephrine (PHE), xylazine (XYL), tyramine (TYR), dopamine (DA), 5-hydroxytryptamine (5-HT), prostaglandin F2 alpha (PGF2 alpha) and KCl were examined in human posterior ciliary arteries (HPCAs) which were isolated and perfused with Tyrode's solution gassed w...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Ohkubo H,Chiba S

    更新日期：1988-01-01 00:00:00

  • Effects of voxel size on detection of lateral geniculate nucleus activation in functional magnetic resonance imaging.

    abstract：PURPOSE:To study the effect of voxel size on the detection of lateral geniculate nucleus (LGN) activation during visual stimulation using functional magnetic resonance imaging (fMRI) at 1.5 T. METHODS:Ten normal subjects were scanned during visual stimulation with flashing goggles, four times, with four different voxe...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-004-0124-5

    authors： Miki A,Liu CS,Liu GT

    更新日期：2004-11-01 00:00:00

  • Histochemical studies of the separation of the lens vesicle in the mouse.

    abstract：:Histochemical studies were carried out in the mouse on the changes and distribution patterns of glycosaminoglycan molecular species during the separation of the lens vesicle. To obtain embryos, pregnant mice of the Jcl:ICR strain were sacrificed on day 10.5 or 11 of pregnancy. Serial frontal sections were strained wit...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Mizuno S,Ikeda K,Hirabayashi Y

    更新日期：1995-01-01 00:00:00

  • Effect of spectacle lenses designed to reduce relative peripheral hyperopia on myopia progression in Japanese children: a 2-year multicenter randomized controlled trial.

    abstract：PURPOSE:Novel spectacle lenses (MyoVision, Carl Zeiss) designed to reduce relative peripheral hyperopia have been developed and reported to be effective for preventing myopia progression in a subgroup of Chinese children. In this study we examined the efficacy of MyoVision lenses in Japanese children. STUDY DESIGN:Thi...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1007/s10384-018-0616-3

    authors： Kanda H,Oshika T,Hiraoka T,Hasebe S,Ohno-Matsui K,Ishiko S,Hieda O,Torii H,Varnas SR,Fujikado T

    更新日期：2018-09-01 00:00:00

  • Spatial distribution of macular pigment estimated by autofluorescence imaging in elderly Japanese individuals.

    abstract：PURPOSE:To determine the spatial distribution types of macular pigment (MP) in elderly Japanese individuals and to consider their origin. STUDY DESIGN:Observational case series. METHODS:Local MP optical density (MPOD) at some eccentricities and MP volume were measured using the MPOD module of a MultiColor Spectralis ...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-020-00716-5

    authors： Obana A,Gohto Y,Sasano H,Gellermann W,Sharifzadeh M,Seto T,Bernstein PS

    更新日期：2020-03-01 00:00:00