Analysis of cytokine mRNAs in murine herpes simplex virus type 1 retinitis.

abstract：:The effects of three sulfhydryl agents on the cytoskeletal systems of cultured human trabecular cells were examined by the immunofluorescence method. Incubation with iodoacetamide or N-ethyl maleimide (10(-6) M, 10(-5) M, and 10(-4) M) caused a marked alteration on the actin and microtubule organization, but had littl...

journal_title：Japanese journal of ophthalmology

authors： Iwamoto Y,Tamura M,Nakatsuka K,Yamanouchi U

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:To compare the cytotoxicity of povidone-iodine solution (PVP-I) with that of polyvinyl alcohol-iodine solution (PAI) for ophthalmic use. METHODS:Cells of the human corneal epithelial cell line HCE-T were exposed to various dilutions of PVP-I or PAI, and the cytotoxicity of these two antiseptics was evaluated. ...

journal_title：Japanese journal of ophthalmology

authors： Shibata Y,Tanaka Y,Tomita T,Taogoshi T,Kimura Y,Chikama T,Kihira K

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:To assess whether the outcomes of toric intraocular lens (IOL) implantation in eyes with oblique astigmatism can be improved by direct measurements of posterior corneal astigmatism using anterior segment optical coherence tomography (AS-OCT) instead of by using anterior corneal measurements alone. STUDY DESIGN...

journal_title：Japanese journal of ophthalmology

authors： Nakano S,Iida M,Hasegawa Y,Hiraoka T,Oshika T

更新日期：2021-01-28 00:00:00

abstract：PURPOSE:To elucidate the characterization of intraocular pressure (IOP) spike after trabeculotomy, and after the combined procedure of phacoemulsification and aspiration (PEA) and intraocular lens (IOL) implantation. METHODS:Included in this study were 39 patients (53 eyes) with primary open-angle glaucoma with IOPs u...

journal_title：Japanese journal of ophthalmology

authors： Inatani M,Tanihara H,Muto T,Honjo M,Okazaki K,Kido N,Honda Y

更新日期：2001-05-01 00:00:00

abstract：PURPOSE:To evaluate the functional status in daily life and the quality of life (QOL) of pathologic myopia patients. METHODS:A cross-sectional study was conducted using data of consecutive pathologic myopia patients (n = 200) and control subjects (n = 144). The influence of the disease on the daily life and the QOL of...

journal_title：Japanese journal of ophthalmology

authors： Takashima T,Yokoyama T,Futagami S,Ohno-Matsui K,Tanaka H,Tokoro T,Mochizuki M

更新日期：2001-01-01 00:00:00

abstract：:We studied the inhibitory effects of chicken egg white ovomacroglobulin, a broad-spectrum protease inhibitor, and a synthetic protease inhibitory peptide, Bz-GFR-O-mercaptoanilide, on the growth of two strains of Serratia marcescens in a synthetic medium. The growth of the virulent protease-producing strain, S. marces...

journal_title：Japanese journal of ophthalmology

authors： Miyagawa S,Matsumoto K,Kamata R,Okamura R,Maeda H

更新日期：1991-01-01 00:00:00

abstract：:Fluoroquinolones provide an important single antibiotic therapy for bacterial keratitis caused by Staphylococcus aureus and numerous gram-negative bacteria, including Pseudomonas aeruginosa. The pharmacokinetics of three ocular fluoroquinolones, norfloxacin (CHIBOXIN, Merck, Sharp & Dohme), ciprofloxacin (CILOXAN, Alc...

journal_title：Japanese journal of ophthalmology

authors： Green LC,Callegan MC,Engel LS,Shimomura Y,Jasheway DW,O'Callaghan RJ,Hill JM

更新日期：1996-01-01 00:00:00

abstract：:Experimental melanin-protein induced uveitis (EMIU) is a CD4 T cell-mediated disease involving the choroid and iris, but sparing the retina. The present study was designed to solubilize uveitogenic antigen from melanin granules without enzymatic digestion, and to investigate some of its elements by comparison with dif...

journal_title：Japanese journal of ophthalmology

authors： Broekhuyse RM,Kuhlmann ED,Winkens HJ

更新日期：1996-01-01 00:00:00

abstract：:Management of intraocular tumors, specifically uveal melanoma, is a matter of controversy. The treatment of these ocular neoplasms varies from observation to enucleation, irradiation (cobalt plaque and proton-helium particle) and eye wall resection. Over the last 18 years, we have developed two techniques for surgical...

journal_title：Japanese journal of ophthalmology

authors： Peyman GA,Gremillion CM

更新日期：1989-01-01 00:00:00

abstract：:Purpose: A young patient of ophthalmoplegic migraine with recurrent oculomotor nerve palsy is reported.Case: A 4-year-old girl came to our hospital complaining of recurrent left ptosis and double vision which completely resolved within a few days. She had a history of drowsiness after vomiting every two months. Left o...

journal_title：Japanese journal of ophthalmology

authors： Ishikawa H,Yoshihara M,Mizuki K,Kashima Y

更新日期：2000-09-01 00:00:00

abstract：PURPOSE:To study the effects of epigenetic events on corneal barrier functions, we examined tight junctions (TJs), the most important factor in the barrier function of the cornea, by using in vitro and in vivo corneal trauma models. METHODS:We examined alteration of TJ-associated gene expression and corneal barrier fu...

journal_title：Japanese journal of ophthalmology

authors： Nishikiori N,Sawada N,Ohguro H

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:To investigate various XLRS1 (RS1) gene mutations in Chinese families with X-linked juvenile retinoschisis (XLRS or RS). METHODS:Genomic DNA was isolated from leukocytes of 29 male patients with X-linked juvenile retinoschisis, 38 female carriers, and 100 normal controls. All 6 exons of the RS1 gene were ampli...

journal_title：Japanese journal of ophthalmology

authors： Ma X,Li X,Wang L

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Interferon (IFN)-associated retinopathy is typically characterized by retinal hemorrhages and cotton wool spots at the posterior fundus, but visual function is usually maintained. With the use of optical coherence tomography (OCT), two patients with IFN-associated retinopathy who had developed macular edema ...

journal_title：Japanese journal of ophthalmology

authors： Shimura M,Saito T,Yasuda K,Tamai M

更新日期：2005-05-01 00:00:00

abstract：:Fibronectin (FN) has been detected at the site of corneal wounds. To investigate whether FN is supplied by the cornea itself or by extracorneal sources, we cultured small blocks of rabbit cornea in vitro with and without autologous serum (5%). The sliding rate of epithelial cells was determined and localization of FN ...

journal_title：Japanese journal of ophthalmology

authors： Nishida T,Nakagawa S,Ohashi Y,Awata T,Manabe R

更新日期：1982-01-01 00:00:00

abstract：:Lymphatic sinus-like structures were demonstrated in the choroid of the monkey eye by transmission and scanning electron microscopy. These lymphatic sinus-like structures were lined by fibroblast-like cells with large intercellular gaps. When the specimens were viewed by scanning electron microscopy, the surface morph...

journal_title：Japanese journal of ophthalmology

authors： Sugita A,Inokuchi T

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:To determine the morphological characteristics of the cornea in eyes with posterior corneal vesicles (PCV) determined by in vivo confocal microscopy (IVCM). In addition, to compare the morphological characteristics of the corneas of eyes with PCV to those of eyes with posterior polymorphous corneal dystrophy (P...

journal_title：Japanese journal of ophthalmology

authors： Shiraishi A,Zheng X,Sakane Y,Hara Y,Hayashi Y

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:To investigate mutations of causal genes in two affected male siblings of a Japanese family with suspected Leber congenital amaurosis (LCA) and to characterize the related clinical features. METHODS:After obtaining informed consent, genomic DNA was extracted from peripheral blood of the proband and his family ...

journal_title：Japanese journal of ophthalmology

authors： Suzuki T,Fujimaki T,Yanagawa A,Arai E,Fujiki K,Wada Y,Murakami A

更新日期：2014-11-01 00:00:00

abstract：:Astrocytes were cultured from the cerebral cortices of newborn rabbits and were so confirmed by staining of the glial fibrillary acidic protein (GFAP). In Experiment I, the astrocytes of newborn rabbits of both sexes from one mother were pooled and suspended in a culture medium, and approximately 1-2 X 10(4) cells wer...

journal_title：Japanese journal of ophthalmology

authors： Mishima N,Yamashita H,Ishii Y,Hori S

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:To determine whether P7C3-A20, a proneurogenic neuroprotective agent, can protect the retinal ganglion cells (RGCs) of rats from optic nerve crushing. METHODS:The left optic nerve of 67 rats was crushed, and 5.0 mg/kg/day of P7C3-A20 (crush-P7C3) or its vehicle (crush-placebo) was injected intraperitoneally fo...

journal_title：Japanese journal of ophthalmology

authors： Oku H,Morishita S,Horie T,Nishikawa Y,Kida T,Mimura M,Kojima S,Ikeda T

更新日期：2017-03-01 00:00:00

abstract：:We evaluated the clinical statistics of a total of 186 patients (101 men and 85 women) with Vogt-Koyanagi-Harada's disease seen in the Uveitis Survey Clinic of the Hokkaido University Hospital during the 18-year period from 1966 to 1983. The annual number of new cases showed some change. More new patients were seen in...

journal_title：Japanese journal of ophthalmology

authors： Ohno S,Minakawa R,Matsuda H

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To evaluate the effect of tetramethylpyrazine on the elevation of aqueous flare and intraocular pressure (IOP) induced by prostaglandin (PG) E(2) and PGE(2) receptor (EP) agonists. METHODS:PGE(2) or EP agonists (11-deoxy PGE(1), EP(2) agonist; 17-phenyl trinor PGE(2), EP(1) and EP(3) agonist; or sulprostone, E...

journal_title：Japanese journal of ophthalmology

authors： Kitagawa K,Hayasaka S,Nagaki Y,Watanabe K

更新日期：2001-05-01 00:00:00

abstract：PURPOSE:To examine the effectiveness, safety, and stability of laser subepithelial keratomileusis (LASEK), a modified photorefractive keratectomy for low to moderate myopia. METHODS:This study evaluated the results of LASEK in 48 myopic patients (84 eyes) with a consecutive 6-month follow-up period. Preoperative myopi...

journal_title：Japanese journal of ophthalmology

authors： Lee JB,Choe CM,Seong GJ,Gong HY,Kim EK

更新日期：2002-05-01 00:00:00

abstract：PURPOSE:To evaluate the clinical significance of 5-S-cysteinyldopa (5-S-CD), a major intermediate in melanin synthesis, as a potential diagnostic tumor marker for uveal malignant melanoma. METHODS:The levels of 5-S-CD in the serum were measured by high-performance liquid chromatography in 16 patients with primary uvea...

journal_title：Japanese journal of ophthalmology

authors： Goto H,Usui M,Wakamatsu K,Ito S

更新日期：2001-09-01 00:00:00

abstract：PURPOSE:To examine the effects of topical steroid instillation on central corneal thickness in eyes with bullous keratopathy (BK). STUDY DESIGN:Retrospective case series METHODS: Consecutive patients with BK who did not wish to receive corneal transplantation and were treated with 0.1% betamethasone eyedrops were incl...

journal_title：Japanese journal of ophthalmology

authors： Ono T,Iwasaki T,Yukawa C,Mori Y,Nejima R,Tokunaga T,Amano S,Miyata K

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:To determine the pharmacological response when dysiherbaine acts on cultured Müller cells, considering the glutamate receptor functions. Dysiherbaine is a new excitotoxic amino acid, which was recently isolated from the liquid extract of a certain sponge. METHODS:Retinas of adult rabbits were used to culture t...

journal_title：Japanese journal of ophthalmology

authors： Minei R

更新日期：2002-03-01 00:00:00

abstract：:From the study of 18 pregnancies in 10 patients with toxoplasmic retinochoroiditis, it was concluded that the most important factor to be considered in advising pregnant patients with this disease is whether or not the antibody titer increases during pregnancy rather than the clinical pictures or the absolute values o...

journal_title：Japanese journal of ophthalmology

authors： Oniki S

更新日期：1983-01-01 00:00:00

abstract：PURPOSE:To estimate the melatonin suppression index (MSI), which may reflect the nonvisual photoreception function, through commercially available foldable, clear and yellow-tinted intraocular lenses (IOLs). METHODS:The MSIs for 13 IOL models (6 clear IOLs, 7 yellow-tinted IOLs) with three lens powers were calculated ...

journal_title：Japanese journal of ophthalmology

authors： Sano I,Tanito M,Okuno T,Ishiba Y,Ohira A

更新日期：2014-07-01 00:00:00

abstract：PURPOSE:To develop a novel method for measuring tear break-up time (BUT) by continuously measuring higher order wavefront aberrations using a Hartmann-Shack (H-S) aberrometer. METHODS:Wavefront aberrations up to the sixth order for a 4-mm pupil were measured in six eyes of six normal subjects using an H-S aberrometer....

journal_title：Japanese journal of ophthalmology

authors： Mihashi T,Hirohara Y,Koh S,Ninomiya S,Maeda N,Fujikado T

更新日期：2006-03-01 00:00:00

abstract：:We reported previously familial hypo-retinol-binding proteinemia in a child who developed keratomalacia during measles infection. In the present study, we characterized serum retinol-binding proteins (RBPs) in the affected family members and compared these RBPs with those in the unaffected family members. Immunoblotti...

journal_title：Japanese journal of ophthalmology

authors： Matsuo T,Matsuo N

更新日期：1988-01-01 00:00:00

abstract：:Cell population and proportion of each component cell type in preretinal membranes formed after retinal detachment were studied by light microscopy (LM) and transmission electron microscopy (TEM). The preretinal membranes were surgically obtained from 20 proliferative vitreoretinopathy (PVR) and 7 macular pucker patie...

journal_title：Japanese journal of ophthalmology

authors： Yamashita H,Hori S,Masuda K

更新日期：1986-01-01 00:00:00