Influence of sulfhydryl agents on cytoskeleton in cultured human trabecular cells.

abstract：PURPOSE:To report on isolated central retinal artery occlusion (CRAO) as an initial presentation in two patients with undiagnosed paroxysmal nocturnal hemoglobinuria (PNH). METHODS:CRAO related to the aggravation of PNH was observed in 2 of 98 consecutive PNH patients for 10 years. Ocular and systemic manifestations w...

journal_title：Japanese journal of ophthalmology

authors： Yang HS,Park SH,Choi JR,Kim JG

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To compare the clinical significance of the photopic negative response (PhNRs) elicited by different stimuli from glaucomatous eyes. STUDY DESIGN:Single-center observational study METHOD: Eighty-four eyes of 84 patients with open angle glaucoma (OAG) and 40 eyes of 40 normal subjects were studied. Cone electro...

journal_title：Japanese journal of ophthalmology

authors： Hara Y,Machida S,Ebihara S,Ishizuka M,Tada A,Nishimura T

更新日期：2020-03-01 00:00:00

abstract：:Medical histories with emphasis on malignant disease were obtained on 1,269 first and second degree relatives of 93 probands with retinoblastoma and on 671 first and second degree relatives of 50 age-matched control children. The number of nonocular malignancies expected to occur in first and second degree relatives o...

journal_title：Japanese journal of ophthalmology

authors： Cohen MS,Augsburger JJ,Shields JA,Amsel J,Felberg NT

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:To investigate the recovery of short-wavelength sensitivity in patients who had undergone successful reattachment of a rhegmatogenous retinal detachment with macular involvement. METHODS:Postoperative assessment of the visual acuity and the visual fields by standard achromatic automated perimetry (SAP), and sh...

journal_title：Japanese journal of ophthalmology

authors： Sakai T,Iida K,Tanaka Y,Kohzaki K,Kitahara K

更新日期：2005-07-01 00:00:00

abstract：:The effects of four commercially available irrigating solutions on the spreading of rabbit corneal endothelial cells on various extracellular matrices were studied. Cultured rabbit corneal endothelial cells, suspended in one of the following intraocular irrigating solutions, Opeguard MA, BSS, BSS Plus, lactated Ringer...

journal_title：Japanese journal of ophthalmology

authors： Nishida T,Otori T

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:To investigate various XLRS1 (RS1) gene mutations in Chinese families with X-linked juvenile retinoschisis (XLRS or RS). METHODS:Genomic DNA was isolated from leukocytes of 29 male patients with X-linked juvenile retinoschisis, 38 female carriers, and 100 normal controls. All 6 exons of the RS1 gene were ampli...

journal_title：Japanese journal of ophthalmology

authors： Ma X,Li X,Wang L

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:To identify any possible determinants in the development of uveitis in leprosy patients. METHODS:Human leukocyte antigen (HLA) class I and II antigen, and HLA class II genotypings were analyzed among Japanese leprosy patients. Ninety-three unrelated Japanese leprosy patients (46 patients with a history of uvei...

journal_title：Japanese journal of ophthalmology

authors： Joko S,Numaga J,Maeda H

更新日期：1999-03-01 00:00:00

abstract：PURPOSE:We investigated the keratocyte response and stromal remodeling after corneal incision and photorefractive keratectomy to understand the histophysiological and immunohistochemical differences between these two types of surgery. METHODS:Corneal incision or photorefractive keratectomy was performed in rabbits or ...

journal_title：Japanese journal of ophthalmology

authors： Tanaka T

更新日期：2000-11-01 00:00:00

abstract：:Clinical, pathological and follow-up data on the 1,147 cases of retinoblastoma registered in Japan from 1975 to 1982 were statistically analyzed. The cumulative survival rate of the total 1,147 cases was 93.0% at 5 years and 90.3% at 10 years, calculated by the Kaplan-Meier method. The survival rate for the 757 unilat...

journal_title：Japanese journal of ophthalmology

authors：

更新日期：1992-01-01 00:00:00

abstract：:Takayasu disease was first reported in 1908 by Mikito Takayasu as "a case of peculiar changes in the central retinal vessels." Because in these patients the pulse of the radial artery is impalpable, investigations focusing on the ischemic symptoms of the upper body were conducted. In 1948, Shimizu and Sano named this ...

journal_title：Japanese journal of ophthalmology

authors： Sugiyama K,Ijiri S,Tagawa S,Shimizu K

更新日期：2009-03-01 00:00:00

abstract：:Fluoroquinolones provide an important single antibiotic therapy for bacterial keratitis caused by Staphylococcus aureus and numerous gram-negative bacteria, including Pseudomonas aeruginosa. The pharmacokinetics of three ocular fluoroquinolones, norfloxacin (CHIBOXIN, Merck, Sharp & Dohme), ciprofloxacin (CILOXAN, Alc...

journal_title：Japanese journal of ophthalmology

authors： Green LC,Callegan MC,Engel LS,Shimomura Y,Jasheway DW,O'Callaghan RJ,Hill JM

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:To assess the changes in the size of muscle fibers and the composition of myosin heavy chain (MyHC) isoforms in the global layer (GL) and the orbital layer (OL) of rabbit rectus extraocular muscle (EOM) after recession. METHODS:The right superior rectus muscles of two rabbits were harvested at 3 days or 1, 2, ...

journal_title：Japanese journal of ophthalmology

authors： Park SC,Kim YT,Kim SA,Oh SY

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:To evaluate the degree of ischemia in eyes with retinal vein occlusion (RVO) using swept-source optical coherence tomography angiography (SS-OCTA) with the extended field imaging (EFI) technique, which extends the area encompassed by SS-OCTA by scanning through trial frames fitted with a +20-diopter lens. STUD...

journal_title：Japanese journal of ophthalmology

authors： Kakihara S,Hirano T,Iesato Y,Imai A,Toriyama Y,Murata T

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To evaluate the functional status in daily life and the quality of life (QOL) of pathologic myopia patients. METHODS:A cross-sectional study was conducted using data of consecutive pathologic myopia patients (n = 200) and control subjects (n = 144). The influence of the disease on the daily life and the QOL of...

journal_title：Japanese journal of ophthalmology

authors： Takashima T,Yokoyama T,Futagami S,Ohno-Matsui K,Tanaka H,Tokoro T,Mochizuki M

更新日期：2001-01-01 00:00:00

abstract：:The effects of local hypothermia on postoperative inflammation, electroretinogram (ERG) and histological changes of the retina were evaluated in experimental vitrectomy in pressure-induced ischemic rabbit eyes. The solutions used for intraocular perfusion were maintained at 8 degrees C, 22 degrees C or 38 degrees C. F...

journal_title：Japanese journal of ophthalmology

authors： Tamai K,Toumoto E

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:To shorten the duration of prone positioning after macular hole surgery from 1 week to 1 day, and to evaluate preoperative factors and the initial hole closure rate. METHODS:The subjects were 33 patients (34 eyes) who underwent macular hole surgery between April 1998 and August 1999, and maintained the prone p...

journal_title：Japanese journal of ophthalmology

authors： Isomae T,Sato Y,Shimada H

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:To study the effect of voxel size on the detection of lateral geniculate nucleus (LGN) activation during visual stimulation using functional magnetic resonance imaging (fMRI) at 1.5 T. METHODS:Ten normal subjects were scanned during visual stimulation with flashing goggles, four times, with four different voxe...

journal_title：Japanese journal of ophthalmology

authors： Miki A,Liu CS,Liu GT

更新日期：2004-11-01 00:00:00

abstract：PURPOSE:To investigate the predictive factors of polyp regression after intravitreal ranibizumab injections for polypoidal choroidal vasculopathy (PCV). METHODS:Sixty-nine eyes (69 patients) with treatment-naïve PCV received an initial series of 3-monthly intravitreal ranibizumab injections, followed by as-needed inje...

journal_title：Japanese journal of ophthalmology

authors： Cho HJ,Han SY,Kim HS,Lee TG,Kim JW

更新日期：2015-01-01 00:00:00

abstract：:Full-field electroretinograms (ERGs) provide a basis for establishing the diagnosis of widespread progressive forms of retinitis pigmentosa in early life even at a time when fundus abnormalities visible with the ophthalmoscope are minimal or absent. Patients characteristically show delays in rod or cone b-wave implici...

journal_title：Japanese journal of ophthalmology

authors： Berson EL

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:The involvement of cytokines and chemokines in vitreous fluid is important in the development and progression of diabetic retinopathy (DR) and central retinal vein occlusion (CRVO). In this study, the concentrations of cytokines and chemokines in the vitreous fluid of eyes with DR and CRVO were measured and com...

journal_title：Japanese journal of ophthalmology

authors： Suzuki Y,Nakazawa M,Suzuki K,Yamazaki H,Miyagawa Y

更新日期：2011-05-01 00:00:00

abstract：:The purpose of this study is to elucidate the extension of the corneal endothelium onto the iris surface, a condition which has been found in the eyes with rubeosis iridis in various ocular disorders. Histopathology of the anterior chamber angle was studied by electron microscopy in 6 eyes with neovascular glaucoma oc...

journal_title：Japanese journal of ophthalmology

authors： Nomura T

更新日期：1983-01-01 00:00:00

abstract：:Surgically resected subretinal proliferative tissue (SRP) in proliferative vitreoretinopathy was examined by morphological and immunohistochemical methods. Membranous and strand-like SRPs were observed. Membranous SRP (4 cases) consisted of retinal pigment epithelial cells (RPEs) and a thin layer of extracellular mate...

journal_title：Japanese journal of ophthalmology

authors： Okada M,Ogino N,Matsumura M,Honda Y,Nagai Y

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:In a previous study we demonstrated that the progression of the disease retinitis pigmentosa (RP) can be readily monitored by the mean deviation (MD) measured by Humphrey central 10-2 perimetry, which assesses the sensitivity distribution in the macular area in eyes affected by RP. In the present study, we inve...

journal_title：Japanese journal of ophthalmology

authors： Abe K,Iijima H,Hirakawa H,Tsukahara Y,Toda Y

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Full-thickness macular holes usually develop in the elderly population. To the best of our knowledge, there has been no written report of a nontraumatic macular hole in a pediatric patient. CASE:A 10-year-old girl noticed decreased central vision in her left eye without any history of trauma. OBSERVATIONS:...

journal_title：Japanese journal of ophthalmology

authors： Nakano T,Uemura A,Kanda S,Sakamoto T

更新日期：2005-11-01 00:00:00

abstract：:We investigated the ocular fundus of (NZWXBXSB) F1 mice, which are considered to be a good model for systemic lupus erythematosus (SLE) with antiphospholipid syndrome. The abnormal fundus findings were documented by fundus photography, and the chorioretinal lesions were studied histopathologically. The incidence of oc...

journal_title：Japanese journal of ophthalmology

authors： Nakamura A,Yokoyama T,Kodera S,Zhang D,Hirose S,Shirai T,Kanai A

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:In this report of two Okinawan patients with Beals syndrome and accompanying ocular complications, the symptoms of Beals syndrome and Marfan syndrome are compared. The etiology of these two syndromes is considered in relation to fibrillin. CASES:Case 1 was a 5-year-old boy who showed blue sclera and bilater...

journal_title：Japanese journal of ophthalmology

authors： Takaesu-Miyagi S,Sakai H,Shiroma T,Hayakawa K,Funakoshi Y,Sawaguchi S

更新日期：2004-09-01 00:00:00

abstract：PURPOSE:To evaluate the cycloplegic effect of mixed eye drops containing 0.5% tropicamide and 0.5% phenylephrine in myopic children, and to determine whether their efficacy was associated with their clinical characteristics. METHODS:Eighty-one myopic children (age, mean +/- SD, 11.0 +/- 1.5 years; mean spherical equiv...

journal_title：Japanese journal of ophthalmology

authors： Hamasaki I,Hasebe S,Kimura S,Miyata M,Ohtsuki H

更新日期：2007-03-01 00:00:00

abstract：PURPOSE:The aqueous humor (AH) contains numerous immunosuppressive molecules that contribute to the ocular immune privilege. Here, we mimic an inflammatory environment to analyze the inhibitory effects of the AH on lipopolysaccharide (LPS)-induced maturation of dendritic cells (DC). METHODS:Different concentrations of...

journal_title：Japanese journal of ophthalmology

authors： Wang HF,Liu JL,Jiang XL,Lu JM,Li XL,Song XJ

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:To evaluate the repeatability of corneal deformation parameters measured using a dynamic Scheimpflug analyzer and the impact of baseline clinical factors on the repeatability of each parameter. STUDY DESIGN:Retrospective, cross-sectional study. METHODS:Forty-eight eyes (48 healthy subjects; mean age, 49.0 ± 1...

journal_title：Japanese journal of ophthalmology

authors： Miki A,Maeda N,Asai T,Ikuno Y,Nishida K

更新日期：2017-11-01 00:00:00

abstract：:For the past 30 years, I have worked as a physician-scientist in both the clinic and laboratory setting at a number of university medical schools. Encountering patients in the clinic for whom treatment was not available led me to the laboratory in an attempt to develop the appropriate treatment for future patients. Th...

journal_title：Japanese journal of ophthalmology

authors： Nishida T

更新日期：2012-09-01 00:00:00