Abstract：
:The purpose of this study is to elucidate the extension of the corneal endothelium onto the iris surface, a condition which has been found in the eyes with rubeosis iridis in various ocular disorders. Histopathology of the anterior chamber angle was studied by electron microscopy in 6 eyes with neovascular glaucoma occurring in the advanced stage of diabetic retinopathy. Histopathological findings embraced extensive peripheral anterior synechiae occluding the filtration angle and fibrovascular tissue on the anterior surface of the iris. In addition, formation of a continuous layer of endothelium was observable on the surface of the iris facing the anterior chamber in the 6 eyes. The newly formed endothelium was continuous with the corneal endothelium at the pseudo-angle formed by the attachment of peripheral anterior synechiae. Two types of corneal endothelial cells were found near the pseudoangle, one type with degenerative changes and the other apparently engaged in normal metabolic activity. It may be assumed from these findings that, while the corneal endothelium undergoes degeneration, new cells of unknown origin proliferate on the posterior corneal surface to replace the disrupted corneal endothelium and extend onto the iris surface.
journal_name
Jpn J Ophthalmoljournal_title
Japanese journal of ophthalmologyauthors
Nomura Tsubject
Has Abstractpub_date
1983-01-01 00:00:00pages
193-200issue
1eissn
0021-5155issn
1613-2246journal_volume
27pub_type
杂志文章abstract：PURPOSE:To shorten the duration of prone positioning after macular hole surgery from 1 week to 1 day, and to evaluate preoperative factors and the initial hole closure rate. METHODS:The subjects were 33 patients (34 eyes) who underwent macular hole surgery between April 1998 and August 1999, and maintained the prone p...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(01)00468-3
更新日期：2002-01-01 00:00:00
abstract：:The usefulness of the Fluorotron Master fluorophotometer fitted with a small animal adapter was evaluated with tree shrews. We also determined that the optimal measurement parameters for these animals, which are regarded as promising for experimental use in ophthalmic research, are: fluorescein-Na concentration, 0.5 x...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Severe, white sheathing of the retinal vessels and yellowish-white placoid lesions, suggesting frosted-branch angiitis, were found in both fundi of a 24-year-old woman. Fluorescein angiography showed hypofluorescence of the placoid lesions in the early phase and hyperfluorescence in the late phase. Indocyanine green a...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(98)00045-8
更新日期：1998-11-01 00:00:00
abstract：:Four patients with asteroid hyalosis who complained of seeing multiple spherical floaters were examined. Except for multiple brilliant particles in the gelatinous vitreous, no abnormalities were found by ophthalmoscopic examination. Asteroid bodies usually cause no visual symptoms in most patients. Therefore it is unu...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：PURPOSE:To describe the clinical features and treatment outcomes of severe retinopathy in eyes with incontinentia pigmenti (IP) of infants within a few months of birth. STUDY DESIGN:Retrospective clinical study. METHODS:Six eyes of three patients (6-day-old girl, 5-month-old girl, and 14-day-old boy) with IP were exa...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-020-00768-7
更新日期：2020-11-01 00:00:00
abstract：:The proliferative activity of the lens epithelium in the early stages of cataract crisis was investigated in rats and mice using the 3H-thymidine autoradiographic method with the whole-mount preparations of total lens epithelial cells. Three-week-old Sprague-Dawley (SD) rats were given a diet which included galactose ...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：PURPOSE:To evaluate the capability of optical coherence tomography (OCT), retinal nerve fiber layer (RNFL) thickness, and visual field (VF) measurements in glaucoma progression detection. METHODS:The study examined 62 eyes of 37 glaucoma patients observed over a 3-year period. All eyes underwent at least four serial R...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-013-0254-8
更新日期：2013-09-01 00:00:00
abstract：:A newly developed model of keratoepithelioplasty (KEP) in the rat was used to analyze the effect of anterior chamber-associated immune deviation on the suppression of corneal allograft rejection. The right eyes of Fisher rats received an anterior chamber (AC) injection of lymphocyte suspension from Dark Agouti (DA) ra...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:Inflammation induced by systemic injection of endotoxin can be a good model for endogenous uveitis since ocular inflammation is induced without manipulating the eye. We carried out morphological and biochemical studies in Lewis rats to evaluate the breakdown of the blood-ocular barrier following injection of endotoxin...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:We have adapted intrinsic signal optical imaging of neural activity to the noninvasive functional imaging of the retina. Results to date demonstrate the feasibility and potential of this new method of functional assessment of the retina. In response to visual stimuli, we have imaged reflectance changes in the retina t...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10384-009-0687-2
更新日期：2009-07-01 00:00:00
abstract：PURPOSE:To study the effects of epigenetic events on corneal barrier functions, we examined tight junctions (TJs), the most important factor in the barrier function of the cornea, by using in vitro and in vivo corneal trauma models. METHODS:We examined alteration of TJ-associated gene expression and corneal barrier fu...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-008-0524-z
更新日期：2008-05-01 00:00:00
abstract：PURPOSE:To investigate the expression of beta-defensin in the ocular surface of a mouse experimental allergic conjunctivitis (EAC) model. METHODS:Mouse beta-defensin (mBD)-1 and -2 mRNA expressed in conjunctival tissue of both the EAC and the control group were analyzed by real-time reverse transcriptase-polymerase ch...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-005-0262-4
更新日期：2006-01-01 00:00:00
abstract：:Purpose: To confirm the intraocular dynamics of 1% deuterium (D) labeled alpha-tocopheral acetate (VEA) solution.Methods: The concentrations of D(3)-VEA and D(3)-alpha-tocopherol (VE) derived from D(3)-VEA in the aqueous humor and lens were measured after instilling 1% D(3)-VEA continuously into the cul-de-sac of rat ...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(00)00315-4
更新日期：2001-01-01 00:00:00
abstract：:Purpose: We have developed a new method for quantification of metamorphopsia and applied it to study distorted vision resulting from epiretinal membrane (ERM).Patients and Methods: We prepared a modified Amsler chart, which was a square grid formed by black lines on a white background with 12 cm on a side and divided ...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(00)00157-x
更新日期：2000-05-01 00:00:00
abstract：PURPOSE:To verify, by use of data collected by the Japan Glaucoma Society Survey of Bleb-related Infection (JGSSBI), that bleb morphology changes within 12 months of the development of bleb-related infection. METHODS:JGSSBI data from 57 eyes of 57 patients with primary open-angle glaucoma and normal tension glaucoma w...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10384-015-0398-9
更新日期：2015-09-01 00:00:00
abstract：:Retinol-binding protein (RBP) is a plasma protein with a molecular weight of 21,000 synthesized in the hepatocytes, binding with retinol (vitamin A), and transporting retinol to peripheral tissues. Keratomalacia is caused by a deficiency of vitamin A itself and/or protein-calorie malnutrition. In the latter condition,...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:It has been reported that keratocytes endocytose foreign particles both in vitro and in vivo, suggesting the active participation of keratocytes in corneal wound healing and host defense mechanism. To understand the cellular response and the fate of engulfed foreign particles, we investigated the changes in the lysoso...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Takayasu disease was first reported in 1908 by Mikito Takayasu as "a case of peculiar changes in the central retinal vessels." Because in these patients the pulse of the radial artery is impalpable, investigations focusing on the ischemic symptoms of the upper body were conducted. In 1948, Shimizu and Sano named this ...
journal_title：Japanese journal of ophthalmology
pub_type： 传,历史文章,杂志文章
doi：10.1007/s10384-009-0650-2
更新日期：2009-03-01 00:00:00
abstract：PURPOSE:To identify the cross-sectional characteristics of filtering blebs associated with intraocular pressure (IOP) control at 1 year after trabeculectomy with a square scleral flap and a fornix-based conjunctival flap. METHODS:A retrospective consecutive case series study was conducted. Eighty-four eyes of 79 patie...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-017-0504-2
更新日期：2017-05-01 00:00:00
abstract：:Glycine is an important inhibitory neurotransmitter in the vertebrate retina. Although many reports of glycine localization by the immunocytochemical method have been published, none has distinguished the neurotransmitter function of glycine from metabolic change. If glycine is the neurotransmitter, it seems that it m...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The effect of 3,3'-iminodipropionitrile (IDPN) on experimental intravitreal proliferation in albino rabbits was studied by light and electron microscopy. About 2.5 x 10(5) tissue cultured fibroblasts were injected into the vitreous cavity of albino rabbits. Immediately after the injection, phosphate-buffered solution ...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：PURPOSE:We have found that two aspartyl (Asp-151 and Asp-58) residues of alphaA-crystallin are inverted and isomerized to the biologically uncommon D-beta-Asp residues during aging. In order to elucidate the correlation between the formation of the D-beta-Asp isomer and the environment surrounding the Asp in the protei...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(00)00202-1
更新日期：2000-07-01 00:00:00
abstract：PURPOSE:To evaluate the clinical significance of 5-S-cysteinyldopa (5-S-CD), a major intermediate in melanin synthesis, as a potential diagnostic tumor marker for uveal malignant melanoma. METHODS:The levels of 5-S-CD in the serum were measured by high-performance liquid chromatography in 16 patients with primary uvea...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(01)00393-8
更新日期：2001-09-01 00:00:00
abstract：PURPOSE:To investigate the differences in thickness and depth of the lamina cribrosa (LC) between ocular hypertension (OH) patients and normal control subjects, using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (SD-OCT). METHODS:EDI-OCT data were obtained from the subjects in a cross-sect...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-015-0407-z
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:Diabetes mellitus aggravates carotid occlusive disease, that can manifest as ocular ischemic syndrome (OIS). Ocular manifestations and visual prognosis of OIS in diabetic patients were retrospectively analyzed. METHODS:Twenty-three consecutive diabetic patients with OIS were divided into two groups according t...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0021-5155(98)00057-4
更新日期：1999-01-01 00:00:00
abstract：PURPOSE:To describe baseline measures of refraction, accommodation, and heterophoria in Japanese schoolchildren enrolled in a randomized clinical trial that examines whether progressive addition lenses slow myopic progression compared with single-focus lenses. METHODS:Ninety-five children with myopia between -1.25 and...
journal_title：Japanese journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s10384-004-0131-6
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:To compare the cytotoxicity of povidone-iodine solution (PVP-I) with that of polyvinyl alcohol-iodine solution (PAI) for ophthalmic use. METHODS:Cells of the human corneal epithelial cell line HCE-T were exposed to various dilutions of PVP-I or PAI, and the cytotoxicity of these two antiseptics was evaluated. ...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-014-0348-y
更新日期：2014-11-01 00:00:00
abstract：:An 18-year-old Japanese boy with optic disk drusen associated with left central retinal artery occlusion was reported. Transient central blurred vision, possibly caused by central retinal artery spasm, was noticed as an initial symptom of optic disk drusen in the left eye. Prolonged and repeated spasm might have given...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:Clinical, pathological and follow-up data on the 1,147 cases of retinoblastoma registered in Japan from 1975 to 1982 were statistically analyzed. The cumulative survival rate of the total 1,147 cases was 93.0% at 5 years and 90.3% at 10 years, calculated by the Kaplan-Meier method. The survival rate for the 757 unilat...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：PURPOSE:To assess the proportion of glaucomatous eyes based on the association between optic disc (OD) size and its clinical determinants in the resident population of Namil-myon, Central South Korea. METHODS:Of the 1,532 participants in the Namil study, we included 1,410 Koreans (2,734 eyes) with legible fundus photo...
journal_title：Japanese journal of ophthalmology
pub_type： 杂志文章
doi：10.1007/s10384-014-0303-y
更新日期：2014-03-01 00:00:00
