Effects of tetramethylpyrazine on prostaglandin E(2)- and prostaglandin E(2) receptor agonist-induced disruption of blood-aqueous barrier in pigmented rabbits.

abstract：PURPOSE:To elucidate the current clinical practice patterns of branch retinal vein occlusion (BRVO) management by retina specialists in Japan in the era of anti-vascular endothelial growth factor (VEGF) therapy. STUDY DESIGN:A voting survey using an answer pad system. METHODS:On May 28, 2017, forty-one retina special...

journal_title：Japanese journal of ophthalmology

authors： Ogura Y,Kondo M,Kadonosono K,Shimura M,Kamei M,Tsujikawa A

更新日期：2019-09-01 00:00:00

abstract：:Localization of carbonic anhydrase (CA) was investigated in the rat eye by light and electron microscopy, and the inhibitory effects on CA distribution in the rat eye were compared between dorzolamide and acetazolamide. The cobalt sulfide histochemical method was used to study the CA localization. Acidic osmification ...

journal_title：Japanese journal of ophthalmology

authors： Terashima H,Suzuki K,Kato K,Sugai N

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:To evaluate the changes in aqueous flare in psoriasis patients and to identify the factors that influence the level of aqueous flare. METHODS:We examined the 68 eyes of 34 psoriasis patients and the 68 eyes of 34 healthy subjects with a laser flare-cell meter. Complete dermatologic and ophthalmic examinations ...

journal_title：Japanese journal of ophthalmology

authors： Okamoto F,Umebayasi Y,Ohtsuka F,Hommura S

更新日期：2001-03-01 00:00:00

abstract：PURPOSE:To determine whether the single-flash electroretinogram (ERG) can predict the postoperative outcome in diabetic cases where massive vitreous hemorrhage precludes fundus observation. METHODS:Eighty-five diabetic patients (105 eyes) who underwent vitrectomy due to dense vitreous hemorrhage were studied retrospec...

journal_title：Japanese journal of ophthalmology

authors： Hiraiwa T,Horio N,Terasaki H,Suzuki T,Yamamoto E,Horiguchi M,Miyake Y

更新日期：2003-05-01 00:00:00

abstract：PURPOSE:To study the effects of antiglaucoma eye drops on N-methyl-D-aspartate (NMDA)-induced retinal damage. METHODS:Several antiglaucoma eye drops, beta-blockers, alpha/beta-blockers, an alpha1-blocker, an alpha2-agonist, and a prostaglandin derivative, were topically administrated to NMDA-treated rat eyes daily for...

journal_title：Japanese journal of ophthalmology

authors： Metoki T,Ohguro H,Ohguro I,Mamiya K,Ito T,Nakazawa M

更新日期：2005-11-01 00:00:00

abstract：PURPOSE:We investigated the keratocyte response and stromal remodeling after corneal incision and photorefractive keratectomy to understand the histophysiological and immunohistochemical differences between these two types of surgery. METHODS:Corneal incision or photorefractive keratectomy was performed in rabbits or ...

journal_title：Japanese journal of ophthalmology

authors： Tanaka T

更新日期：2000-11-01 00:00:00

abstract：:A nationwide, multicenter study of typical retinitis pigmentosa (RP) was carried out in collaboration with 18 hospitals throughout Japan to obtain current information for genetic counseling. We analyzed the genetic heterogeneity of RP based on the parental consanguinity of 434 probands registered during a 6-month peri...

journal_title：Japanese journal of ophthalmology

authors： Hayakawa M,Fujiki K,Kanai A,Matsumura M,Honda Y,Sakaue H,Tamai M,Sakuma T,Tokoro T,Yura T,Kubota N,Kawano S,Matsui M,Yuzawa M,Oguchi Y,Akeo K,Adachi E,Kimura T,Miyake Y,Horiguchi M,Wakabayashi K,Ishizaka N,Koi

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:To establish a rat glaucoma model with chronic intraocular pressure (IOP) elevation induced by microbeads suspended in sodium sulfate-sodium hyaluronate. METHODS:Chronic elevation of IOP was induced unilaterally by injecting polystyrene microbeads, suspended in 4 % sodium sulfate and 3 % sodium hyaluronate, in...

journal_title：Japanese journal of ophthalmology

authors： Matsumoto Y,Kanamori A,Nakamura M,Negi A

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:The head-mounted display (HMD) has produced conflict between visual and vestibular stimuli because the HMD image does not move with the head motion of the wearer. The HMD can show binocular parallax three-dimensional (3D) images, in which vergence and accommodation conflict. Thus, the HMD may affect the normal ...

journal_title：Japanese journal of ophthalmology

authors： Ukai K,Saida S,Ishikawa N

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Although human immunodeficiency virus (HIV)-related ocular complexes are commonly observed in acquired immune deficiency syndrome (AIDS) patients, it has not been previously reported that HIV had already invaded the ocular tissues of HIV carriers. CASE:A 56-year-old woman was diagnosed as having rhegmatogen...

journal_title：Japanese journal of ophthalmology

authors： Kashiwagi K,Gohdo T,Sato S,Iijima H,Tsukahara S

更新日期：2000-11-01 00:00:00

abstract：:A 10-year-old girl complained or poor vision in both eyes. The patient showed progeria, physical and mental retardation, sensorineural hearing loss, cutaneous photosensitivity, hyperopia, poor pupillary dilation, exotropia, salt-and-pepper fundi, nondetectable cone and rod electroretinographic (ERG) responses, cerebra...

journal_title：Japanese journal of ophthalmology

authors： Ikeda N,Yamamoto S,Hayasaka S,Fukuo Y,Koike T

更新日期：1995-01-01 00:00:00

abstract：:The complexity of visual field result evaluation has increased with the advent of automated perimetry. This in turn makes software assistance such as provided by the new Octosmart program interesting and desirable. Its accuracy and reliability in visual field evaluation must be tested, though, and the testing methodol...

journal_title：Japanese journal of ophthalmology

authors： Hirsbrunner HP,Fankhauser F,Funkhouser AT,Jenni A

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:The mortality rate of patients with retinoblastoma still varies in developing countries, and data for Asia and Taiwan are relatively scarce. In this retrospective study, we aimed to describe the survival characteristics and prognostic factors of 54 retinoblastoma cases diagnosed at the Taipei Veterans General H...

journal_title：Japanese journal of ophthalmology

authors： Chang CY,Chiou TJ,Hwang B,Bai LY,Hsu WM,Hsieh YL

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:We present the pathological findings at orbital exenteration in a patient with Wyburn-Mason syndrome who underwent transarterial embolization. CASE:A 31-year-old man with a 10-year history of gradual exacerbation of left exophthalmos and left cheek swelling was found to have facial and orbital arteriovenous...

journal_title：Japanese journal of ophthalmology

authors： Matsuo T,Yanai H,Sugiu K,Tominaga S,Kimata Y

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:To examine the effectiveness, safety, and stability of laser subepithelial keratomileusis (LASEK), a modified photorefractive keratectomy for low to moderate myopia. METHODS:This study evaluated the results of LASEK in 48 myopic patients (84 eyes) with a consecutive 6-month follow-up period. Preoperative myopi...

journal_title：Japanese journal of ophthalmology

authors： Lee JB,Choe CM,Seong GJ,Gong HY,Kim EK

更新日期：2002-05-01 00:00:00

abstract：PURPOSE:To identify a mutation in the PRPF31 gene in a family (Family K) with autosomal dominant retinitis pigmentosa (adRP) linked to 19q13.4 (RP11) and to find the frequency of mutations in the PRPF31 gene among Japanese families with adRP. METHODS:Genomic DNA specimens were prepared from five symptomatic and two as...

journal_title：Japanese journal of ophthalmology

authors： Taira K,Nakazawa M,Sato M

更新日期：2007-01-01 00:00:00

abstract：:Distribution of microglia cells was studied in the normal retina of Wistar rats kept in a specific-pathogen-free condition, using a combined technique of light and electron microscopy with the weak silver carbonate staining method of del Rio-Hortega. Typical microglia cells were found mainly in the inner plexiform lay...

journal_title：Japanese journal of ophthalmology

authors： Kohno T,Inomata H,Taniguchi Y

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:To measure choroidal thickness in healthy pregnant women using enhanced depth imaging optical coherence tomography (EDI-OCT) and compare the measurements with those of healthy non-pregnant women. METHODS:Choroidal thickness was measured at the fovea and at 3 mm superior, inferior, temporal, and nasal to the fo...

journal_title：Japanese journal of ophthalmology

authors： Takahashi J,Kado M,Mizumoto K,Igarashi S,Kojo T

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To clarify the redox states of the aqueous humor and serum in senile cataract patients. METHODS:We analyzed the reduced and oxidized albumin fractions in 58 patients. The patients had no detectable evidence of other eye or systemic diseases and were divided into two age groups (53-75 and 76-96 years). Analysis...

journal_title：Japanese journal of ophthalmology

authors： Kawai K,Hayashi T,Matsuyama Y,Minami T,Era S

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:To investigate gelatinase [matrix metalloproteinase (MMP)-2 and MMP-9] expression in the tear fluid of patients with recurrent corneal erosion (RCE). METHODS:Eleven patients with RCE, three patients with traumatic corneal erosion, and 10 control individuals were enrolled in this study. Tear samples from RCE ey...

journal_title：Japanese journal of ophthalmology

authors： Sakimoto T,Shoji J,Yamada A,Sawa M

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To compare the visualization of microaneurysms (MAs) in patients with diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA) with that using fluorescein angiography (FA). STUDY DESIGN:Prospective, clinical, and experimental. METHODS:This study was a prospective evaluation of imaging t...

journal_title：Japanese journal of ophthalmology

authors： Hamada M,Ohkoshi K,Inagaki K,Ebihara N,Murakami A

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To evaluate the degree of ischemia in eyes with retinal vein occlusion (RVO) using swept-source optical coherence tomography angiography (SS-OCTA) with the extended field imaging (EFI) technique, which extends the area encompassed by SS-OCTA by scanning through trial frames fitted with a +20-diopter lens. STUD...

journal_title：Japanese journal of ophthalmology

authors： Kakihara S,Hirano T,Iesato Y,Imai A,Toriyama Y,Murata T

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To verify, by use of data collected by the Japan Glaucoma Society Survey of Bleb-related Infection (JGSSBI), that bleb morphology changes within 12 months of the development of bleb-related infection. METHODS:JGSSBI data from 57 eyes of 57 patients with primary open-angle glaucoma and normal tension glaucoma w...

journal_title：Japanese journal of ophthalmology

authors： Sawada A,Kuwayama Y,Yamamoto T

更新日期：2015-09-01 00:00:00

abstract：:The exfoliation syndrome is thought to be a very rare disease in China. The clinical features of 11 patients with pseudoexfoliation (PE) and the histopathologic changes in specimens affected by PE were studied. The loss of pigment at the pupillary ruff and the dense pigmentation on the trabecular meshwork were the ear...

journal_title：Japanese journal of ophthalmology

authors： Ye TC,Mao WS,Zhang J

更新日期：1989-01-01 00:00:00

abstract：:Conventional vitreoretinal surgery for proliferative vitreoretinopathy is unsatisfactory despite numerous innovations over the past 20 years. Silicone oil injections in this series resulted in 70% reattachment of these end-stage cases, but within twelve months over 90% had no useful visual result. The development of a...

journal_title：Japanese journal of ophthalmology

authors： Constable I

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:To investigate various XLRS1 (RS1) gene mutations in Chinese families with X-linked juvenile retinoschisis (XLRS or RS). METHODS:Genomic DNA was isolated from leukocytes of 29 male patients with X-linked juvenile retinoschisis, 38 female carriers, and 100 normal controls. All 6 exons of the RS1 gene were ampli...

journal_title：Japanese journal of ophthalmology

authors： Ma X,Li X,Wang L

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:To evaluate the safety of retrocorneal plaque aspiration in patients with fungal keratitis. STUDY DESIGN:Retrospective study. METHODS:A retrospective case series of fungal keratitis seen at Kyoto Prefectural University of Medicine between November 2013 and September 2018. Patients with retrocorneal plaque who...

journal_title：Japanese journal of ophthalmology

authors： Kitazawa K,Fukuoka H,Inatomi T,Aziza Y,Kinoshita S,Sotozono C

更新日期：2020-03-01 00:00:00

abstract：:A unilateral intravitreal inoculation of herpes simplex virus type 1 (HSV-1) induced bilateral retinitis and encephalitis in the rat. Immunohistochemistry was employed to clarify the pathway of transmission of HSV-1 from the inoculated eye to the contralateral eye, and to identify localization of the viral antigen in ...

journal_title：Japanese journal of ophthalmology

authors： Matsushima M,Uyama M,Ohyama A,Ueyama T,Sugimoto T

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:This study was performed to assess the impact of dry eye on patients' quality of life (QOL) and to analyze the association between subjective symptoms and ocular surface findings of dry eye. METHODS:The study population consisted of 158 patients with dry eye aged 20 years or older who visited any of the 15 med...

journal_title：Japanese journal of ophthalmology

authors： Mizuno Y,Yamada M,Miyake Y,Dry Eye Survey Group of the National Hospital Organization of Japan.

更新日期：2010-07-01 00:00:00

abstract：:We examined ophthalmologically five affected members of a family with type IIa hyperlipoproteinemia. All of them had increased levels of cholesterol and low-density lipoprotein. Corneal arcus was found in three of the five members; a 50-year-old man, a 43-year-old woman and a 13-year-old boy. We believe that the corne...

journal_title：Japanese journal of ophthalmology

authors： Hayasaka S,Honda M,Kitaoka M,Chiba R

更新日期：1984-01-01 00:00:00