Factors associated with increased aqueous flare in psoriasis.

Abstract:

PURPOSE:To evaluate the changes in aqueous flare in psoriasis patients and to identify the factors that influence the level of aqueous flare. METHODS:We examined the 68 eyes of 34 psoriasis patients and the 68 eyes of 34 healthy subjects with a laser flare-cell meter. Complete dermatologic and ophthalmic examinations were performed on the psoriasis patients. RESULTS:Flare was significantly higher in psoriasis patients than in normal controls (P <.000l). The factors that increased flare significantly were age and Psoriasis Area and Severity Index. Flare was not significantly associated with sex, psoriasis type, duration of disease, and cyclosporin therapy. A flare increase was significantly correlated with serum total protein and immunoglobulin (Ig) A, but not with albumin, IgG, and IgM. CONCLUSIONS:Psoriasis patients, even without ocular symptoms, had slight damage to the blood-aqueous barrier. Multiple linear regression analysis showed that flare had the strongest correlation with the severity of psoriasis.

journal_name

Jpn J Ophthalmol

authors

Okamoto F,Umebayasi Y,Ohtsuka F,Hommura S

doi

10.1016/s0021-5155(00)00359-2

keywords:

subject

Has Abstract

pub_date

2001-03-01 00:00:00

pages

172-6

issue

2

eissn

0021-5155

issn

1613-2246

pii

S0021-5155(00)00359-2

journal_volume

45

pub_type

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