Nondetectable cone and rod electroretinographic responses in a patient with Cockayne syndrome.

abstract：BACKGROUND:In this report of two Okinawan patients with Beals syndrome and accompanying ocular complications, the symptoms of Beals syndrome and Marfan syndrome are compared. The etiology of these two syndromes is considered in relation to fibrillin. CASES:Case 1 was a 5-year-old boy who showed blue sclera and bilater...

journal_title：Japanese journal of ophthalmology

authors： Takaesu-Miyagi S,Sakai H,Shiroma T,Hayakawa K,Funakoshi Y,Sawaguchi S

更新日期：2004-09-01 00:00:00

abstract：:We have adapted intrinsic signal optical imaging of neural activity to the noninvasive functional imaging of the retina. Results to date demonstrate the feasibility and potential of this new method of functional assessment of the retina. In response to visual stimuli, we have imaged reflectance changes in the retina t...

journal_title：Japanese journal of ophthalmology

authors： Ts'o D,Schallek J,Kwon Y,Kardon R,Abramoff M,Soliz P

更新日期：2009-07-01 00:00:00

abstract：:For the past 30 years, I have worked as a physician-scientist in both the clinic and laboratory setting at a number of university medical schools. Encountering patients in the clinic for whom treatment was not available led me to the laboratory in an attempt to develop the appropriate treatment for future patients. Th...

journal_title：Japanese journal of ophthalmology

authors： Nishida T

更新日期：2012-09-01 00:00:00

abstract：:A surgically obtained lens from a 66-year-old man with the Weill-Marchesani syndrome was examined histopathologically by light microscopy, transmission electron microscopy and scanning electron microscopy. The lens was diffusely opaque and brown. It was microspherophakic in appearance, 6.0 mm in equatorial diameter an...

journal_title：Japanese journal of ophthalmology

authors： Nagata M,Takagi S,Yamasaki A,Tsunematsu S,Kumagami T,Itamochi C,Tamai A

更新日期：1995-01-01 00:00:00

abstract：:Three cases of medullated nerve fibers of the retina were seen. They had medullated nerve fibers in both the upper and lower quadrants of the temporal retina, whereby the temporal raphe of the retinal nerve fiber layer could be visualized. Some nerve fibers from the upper and lower quadrants crossed each other on the ...

journal_title：Japanese journal of ophthalmology

authors： Sakai T,Sano K,Tsuzuki K,Ueno M,Kawamura Y

更新日期：1987-01-01 00:00:00

abstract：:Latanoprost (PhXA41, Xalatan) and isopropyl unoprostone (UF-021, unoprostone, Rescula) two new prostanoid derivatives, have been shown to reduce intraocular pressure (IOP) significantly in patients with glaucoma or ocular hypertension. This study was designed to compare the ocular hypotensive effects of latanoprost an...

journal_title：Japanese journal of ophthalmology

authors： Serle JB,Podos SM,Kitazawa Y,Wang RF

更新日期：1998-03-01 00:00:00

abstract：PURPOSE:To assess serial dynamic enhanced computed tomography (serial DE-CT) as a diagnostic tool for carotid-cavernous sinus fistula (CCF). METHODS:Serial DE-CT was performed in seven patients (ages 31-74) with CCF. Contrast material was injected intravenously at a dose of 60 mL with an injection speed of 4 mL per se...

journal_title：Japanese journal of ophthalmology

authors： Ohtsuka K,Hashimoto M

更新日期：1999-11-01 00:00:00

abstract：PURPOSE:The involvement of cytokines and chemokines in vitreous fluid is important in the development and progression of diabetic retinopathy (DR) and central retinal vein occlusion (CRVO). In this study, the concentrations of cytokines and chemokines in the vitreous fluid of eyes with DR and CRVO were measured and com...

journal_title：Japanese journal of ophthalmology

authors： Suzuki Y,Nakazawa M,Suzuki K,Yamazaki H,Miyagawa Y

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To determine the psychological state and personality traits of patients with retinitis pigmentosa (RP) or glaucoma so that a closer and better relationship can be developed with the patients. METHODS:The Yatabe-Guilford personality test was administered to 75 RP patients and 42 glaucoma patients. The latter gr...

journal_title：Japanese journal of ophthalmology

authors： Igarashi Y,Sato E,Ito A,Miyauchi O,Ikejiri M,Hanawa T,Tsuyama Y,Mizota A,Fujimoto N,Adachi-Usami E

更新日期：2003-01-01 00:00:00

abstract：:A 76-year-old Japanese woman had suffered from fatigue, weight loss, and cutaneous hyperpigmentation at the age of 38 years and was diagnosed as having tuberculous Addison's disease. Since then, corticosteroids had been administered effectively as hormonal replacement. At the age of 75 years, the patient presented wit...

journal_title：Japanese journal of ophthalmology

authors： Kakiuchi T,Uehara F,Ohba N

更新日期：1998-09-01 00:00:00

abstract：:Background: We report three eyes of two patients with rubella retinopathy which were associated with choroidal neovascularization in the macula.Cases: A 7-year-old girl (case 1) and a 12-year-old girl (case 2) whose mothers had suffered rubella during their pregnancy revealed typical rubella retinopathy in both eyes a...

journal_title：Japanese journal of ophthalmology

authors： Hirano K,Tanikawa A,Miyake Y

更新日期：2000-11-01 00:00:00

abstract：:Purpose: We investigated the relationship between the progression of visual field defect and clinical factors in patients with normal-tension glaucoma (NTG).Subjects and Methods: Forty-eight eyes of 48 NTG patients undergoing more than 5-year follow-up were enrolled in this study. Their visual field defects ranged bet...

journal_title：Japanese journal of ophthalmology

authors： Tanaka C,Yamazaki Y,Yokoyama H

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:To evaluate the effectiveness of the isolated caruncular approach to orbital decompression of thyroid ophthalmopathy. METHODS:In a retrospective, noncomparative, interventional case series, we reviewed the records of 29 patients (48 orbits) who had thyroid ophthalmopathy and had undergone orbital decompression...

journal_title：Japanese journal of ophthalmology

authors： Woo KI,Kim YD

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:Defensins are antimicrobial peptides and are classified into three groups, alpha-, beta- and theta-defensins. We investigated the localization of human neutrophil peptides (HNP) 1-3, which are members of the alpha-defensin subfamily, and the expression of human beta-defensin 1 (hBD-1) and hBD-2 in the ocular su...

journal_title：Japanese journal of ophthalmology

authors： Ikeda A,Sakimoto T,Shoji J,Sawa M

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:To determine whether photoreceptor degeneration in transgenic (Tg) rabbits carrying the Pro347Leu rhodopsin mutation alters the neural activity of the middle and inner retinal neurons. METHODS:Multifocal electroretinograms (mfERGs) were recorded from eight 12-week-old Tg rabbits both before and after intravitr...

journal_title：Japanese journal of ophthalmology

authors： Yokoyama D,Machida S,Kondo M,Terasaki H,Nishimura T,Kurosaka D

更新日期：2010-09-01 00:00:00

abstract：:The complexity of visual field result evaluation has increased with the advent of automated perimetry. This in turn makes software assistance such as provided by the new Octosmart program interesting and desirable. Its accuracy and reliability in visual field evaluation must be tested, though, and the testing methodol...

journal_title：Japanese journal of ophthalmology

authors： Hirsbrunner HP,Fankhauser F,Funkhouser AT,Jenni A

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To evaluate the relation between higher order aberrations (HOAs) and contrast sensitivity function (CSF) in a population with myopia. METHODS:In this case series, HOAs were measured in 70 myopic eyes over a 6-mm pupil. Contrast sensitivity was also measured. From the contrast sensitivity data, the area under t...

journal_title：Japanese journal of ophthalmology

authors： Feizi S,Karimian F

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:To compare the detection of localized retinal nerve fiber layer (RNFL) defects by two different spectral domain optical coherence tomography (SD-OCT) devices. METHODS:Eyes of 42 normal control subjects and 48 patients with a localized RNFL defect on red-free fundus photographs were imaged by the Cirrus (Carl Z...

journal_title：Japanese journal of ophthalmology

authors： Kim KE,Ahn SJ,Kim DM

更新日期：2013-07-01 00:00:00

abstract：:The value of the polymerase chain reaction (PCR) in the diagnosis of stromal herpetic keratitis was examined using tear fluid specimens; the sensitivity of the nested PCR method in detecting the herpes simplex virus (HSV) genome was 1 plaque-forming unit/mL. PCR assay of 72 tear samples from the eyes of 15 patients wi...

journal_title：Japanese journal of ophthalmology

authors： Kudo E,Shiota H,Kinouchi Y,Mimura Y,Itakura M

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:To evaluate the functional surgical success, complications, and degree of satisfaction after endoscopy-guided transcaruncular Jones tube intubation without dacryocystorhinostomy (DCR). METHODS:A pair of Westcott scissors was passed into the nose from the side of the caruncle, and the lacrimal bone was penetrat...

journal_title：Japanese journal of ophthalmology

authors： Choi WC,Yang SW

更新日期：2006-03-01 00:00:00

abstract：:It is unknown whether aqueous flare is increased in eyes with prominent fundus lesions other than choroidal malignant melanoma. Therefore, we studied the aqueous flare in eyes with age-related macular degeneration (ARMD) using the laser flare-cell meter. Forty-three eyes of 27 patients with ARMD (age 67.0 +/- 14.0 yea...

journal_title：Japanese journal of ophthalmology

authors： Kubota T,Küchle M,Nguyen NX

更新日期：1994-01-01 00:00:00

abstract：:To investigate the true structural changes in retinal cotton wool spots, serial sections of several blocks of retinal corresponding to cotton wool spots obtained from two hypertensive cases were studied by light and electron microscopy. Occlusion of the feeder arteriole and capillaries, and numerous vacuoles of variou...

journal_title：Japanese journal of ophthalmology

authors： Murata M,Yoshimoto H

更新日期：1983-01-01 00:00:00

abstract：:We reported previously familial hypo-retinol-binding proteinemia in a child who developed keratomalacia during measles infection. In the present study, we characterized serum retinol-binding proteins (RBPs) in the affected family members and compared these RBPs with those in the unaffected family members. Immunoblotti...

journal_title：Japanese journal of ophthalmology

authors： Matsuo T,Matsuo N

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To shorten the duration of prone positioning after macular hole surgery from 1 week to 1 day, and to evaluate preoperative factors and the initial hole closure rate. METHODS:The subjects were 33 patients (34 eyes) who underwent macular hole surgery between April 1998 and August 1999, and maintained the prone p...

journal_title：Japanese journal of ophthalmology

authors： Isomae T,Sato Y,Shimada H

更新日期：2002-01-01 00:00:00

abstract：:Purpose: To evaluate the usefulness of a new fixation monitoring system called gaze tracking in the perimetry of glaucomatous eyes. Subjects and Method: We studied the visual field of 106 eyes in 106 persons, comprising 74 eyes with open-angle glaucoma and 32 eyes with ocular hypertension. Perimetry was performed usin...

journal_title：Japanese journal of ophthalmology

authors： Kunimatsu S,Suzuki Y,Shirato S,Araie M

更新日期：2000-03-01 00:00:00

abstract：PURPOSE:To analyze mutations of the arrestin/S-antigen (SAG) gene in nine newly identified Oguchi disease patients, and to examine whether the 926delA (formerly called 1147delA) mutation in the SAG gene is inherited from a single founder. METHODS:DNA samples were assayed for mutations around nucleotide 926 of the SAG ...

journal_title：Japanese journal of ophthalmology

authors： Saga M,Mashima Y,Kudoh J,Oguchi Y,Shimizu N

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:To establish with negative electroretinogram (ERG) the clinical entity of eight patients with unilateral severe photophobia, essentially normal fundus, good visual acuity, and severe cone and rod dysfunction. STUDY DESIGN:Multicenter retrospective observation case series. METHODS:Comprehensive ophthalmologic ...

journal_title：Japanese journal of ophthalmology

authors： Hirakata T,Fujinami K,Saito W,Kanda A,Hirakata A,Ishida S,Murakami A,Tsunoda K,Miyake Y

更新日期：2020-11-12 00:00:00

abstract：PURPOSE:We previously reported that human conjunctival epithelial cells expressed functioning interleukin-4 receptor α (IL-4Rα). In this study, we investigated whether human corneal epithelial cells also express functioning IL-4Rα. METHODS:The presence of IL-4Rα mRNA and protein in human corneal epithelium was examine...

journal_title：Japanese journal of ophthalmology

authors： Ueta M,Sotozono C,Kinoshita S

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:To compare the cytotoxicity of povidone-iodine solution (PVP-I) with that of polyvinyl alcohol-iodine solution (PAI) for ophthalmic use. METHODS:Cells of the human corneal epithelial cell line HCE-T were exposed to various dilutions of PVP-I or PAI, and the cytotoxicity of these two antiseptics was evaluated. ...

journal_title：Japanese journal of ophthalmology

authors： Shibata Y,Tanaka Y,Tomita T,Taogoshi T,Kimura Y,Chikama T,Kihira K

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:To describe the epidemiology and clinical outcomes of open globe injuries (OGIs) in Japan over 10 years, and examine preoperative factors influencing the visual prognosis after surgery. STUDY DESIGN:Retrospective, observational, multicenter case-series study. METHODS:Patients' data were entered into a compute...

journal_title：Japanese journal of ophthalmology

authors： Okamoto Y,Morikawa S,Okamoto F,Inomoto N,Ishikawa H,Ueda T,Sakamoto T,Sugitani K,Oshika T

更新日期：2019-01-01 00:00:00