Aqueous flare in eyes with age-related macular degeneration.

abstract：:A nationwide, multicenter study of typical retinitis pigmentosa (RP) was carried out in collaboration with 18 hospitals throughout Japan to obtain current information for genetic counseling. We analyzed the genetic heterogeneity of RP based on the parental consanguinity of 434 probands registered during a 6-month peri...

journal_title：Japanese journal of ophthalmology

authors： Hayakawa M,Fujiki K,Kanai A,Matsumura M,Honda Y,Sakaue H,Tamai M,Sakuma T,Tokoro T,Yura T,Kubota N,Kawano S,Matsui M,Yuzawa M,Oguchi Y,Akeo K,Adachi E,Kimura T,Miyake Y,Horiguchi M,Wakabayashi K,Ishizaka N,Koi

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Although human immunodeficiency virus (HIV)-related ocular complexes are commonly observed in acquired immune deficiency syndrome (AIDS) patients, it has not been previously reported that HIV had already invaded the ocular tissues of HIV carriers. CASE:A 56-year-old woman was diagnosed as having rhegmatogen...

journal_title：Japanese journal of ophthalmology

authors： Kashiwagi K,Gohdo T,Sato S,Iijima H,Tsukahara S

更新日期：2000-11-01 00:00:00

abstract：PURPOSE:To evaluate the functional surgical success, complications, and degree of satisfaction after endoscopy-guided transcaruncular Jones tube intubation without dacryocystorhinostomy (DCR). METHODS:A pair of Westcott scissors was passed into the nose from the side of the caruncle, and the lacrimal bone was penetrat...

journal_title：Japanese journal of ophthalmology

authors： Choi WC,Yang SW

更新日期：2006-03-01 00:00:00

abstract：PURPOSE:To investigate global protein expression profiles in the retinas of normal and glucocorticoid-induced ocular hypertensive rats by proteomic analysis. METHODS:Ocular hypertension was induced by topical application of dexamethasone (DEX) for 4 weeks. Age-matched untreated rats served as controls. Intraocular pre...

journal_title：Japanese journal of ophthalmology

authors： Miyara N,Shinzato M,Yamashiro Y,Iwamatsu A,Kariya KI,Sawaguchi S

更新日期：2008-03-01 00:00:00

abstract：:The ocular penetration of two beta-adrenergic blockers, befunolol and timolol, was studied using albino and pigmented rabbits. A 1% ophthalmic solution of 14C-befunolol hydrochloride or 14C-timolol maleate was instilled in one eye of nonsedated rabbits, and the concentrations of radioactive material in the ocular tiss...

journal_title：Japanese journal of ophthalmology

authors： Araie M,Takase M,Sakai Y,Ishii Y,Yokoyama Y,Kitagawa M

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:We report a patient with a limited form of Wegener's granulomatosis (WG) who presented with ocular changes and an eyelid ulcer in her left eye. CASE:A 56-year-old woman complained of ocular pain and discharge. Upon examination, we found evidence of ulcerative keratitis, a mass in the orbit, and an eyelid sk...

journal_title：Japanese journal of ophthalmology

authors： Kubota T,Hirose H

更新日期：2003-07-01 00:00:00

abstract：PURPOSE:To investigate the clinical characteristics of eyes with cuticular drusen in Japanese individuals, while paying special attention to large colloid drusen (LCD). STUDY DESIGN:Retrospective case series. METHODS:Eyes with cuticular drusen, from patients of 4 medical institutes in Japan, were investigated. Multim...

journal_title：Japanese journal of ophthalmology

authors： Sakurada Y,Tanaka K,Miki A,Matsumoto H,Kawamura A,Mukai R,Akiyama H,Honda S,Mori R,Iijima H

更新日期：2019-11-01 00:00:00

abstract：PURPOSE:The aim of this study was to experimentally investigate changes in visible light-induced photo-oxidation and to evaluate the inhibitory effect of various acrylic tinted intraocular lenses (IOLs) on photooxidation. METHODS:Three types of nontinted (VA-60BB, HOYA; SA60AT, Alcon; AU-6, Menicon) and tinted (YA-60B...

journal_title：Japanese journal of ophthalmology

authors： Mukai K,Matsushima H,Sawano M,Nobori H,Obara Y

更新日期：2009-01-01 00:00:00

abstract：:The glycocalyx, present on the surface of the corneal epithelium, contains sialoglycoconjugates. The developmental change in the sialylated residues may be evaluated by examining the expression of the sialyltransferase mRNA. We examined the distribution of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase mRNA in rat cor...

journal_title：Japanese journal of ophthalmology

authors： Uehara F,Ozawa M,Iwakiri N,Ohba N

更新日期：1995-01-01 00:00:00

abstract：:For the past 30 years, I have worked as a physician-scientist in both the clinic and laboratory setting at a number of university medical schools. Encountering patients in the clinic for whom treatment was not available led me to the laboratory in an attempt to develop the appropriate treatment for future patients. Th...

journal_title：Japanese journal of ophthalmology

authors： Nishida T

更新日期：2012-09-01 00:00:00

abstract：:A computerized digital image analysis system was developed to evaluate the retinal nerve fiber layer (RNFL) by red-free fundus photography. The image intensity of the RNFL was computed for 30 degrees between the disc and macula. Thirty early open-angle glaucoma patients and 30 normal age-matched subjects were examined...

journal_title：Japanese journal of ophthalmology

authors： Yamazaki Y,Miyazawa T,Yamada H

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Epidermal nevus syndrome encompasses a group of congenital neurocutaneous anomalies characterized by epidermal nevi in association with cerebral, ocular, and skeletal abnormalities. We report herein the case of a Japanese girl with epidermal nevus syndrome associated with complex ocular choristoma and discus...

journal_title：Japanese journal of ophthalmology

authors： Miyagawa Y,Nakazawa M,Kudoh T

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of intravitreal drug injections using a short 34-gauge needle. STUDY DESIGN:Retrospective study. METHODS:This study included patients with age-related macular degeneration, diabetic macular edema, or macular edema associated with retinal vein occlusion. We reviewed the medi...

journal_title：Japanese journal of ophthalmology

authors： Sasajima H,Tsuboi K,Murotani K,Kamei M

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:To measure choroidal thickness in healthy pregnant women using enhanced depth imaging optical coherence tomography (EDI-OCT) and compare the measurements with those of healthy non-pregnant women. METHODS:Choroidal thickness was measured at the fovea and at 3 mm superior, inferior, temporal, and nasal to the fo...

journal_title：Japanese journal of ophthalmology

authors： Takahashi J,Kado M,Mizumoto K,Igarashi S,Kojo T

更新日期：2013-09-01 00:00:00

abstract：:Using polymerase chain reaction, we detected the varicella-zoster virus genome in the vitreous humor of two patients with clinically diagnosed acute retinal necrosis. One of the two cases was thought to be caused by infection with a varicella-zoster virus lacking a PstI cleavage site. We could not find any clinical di...

journal_title：Japanese journal of ophthalmology

authors： Mochizuki K,Matsushita H,Hiramatsu Y,Yanagida K

更新日期：1998-05-01 00:00:00

abstract：:To investigate the true structural changes in retinal cotton wool spots, serial sections of several blocks of retinal corresponding to cotton wool spots obtained from two hypertensive cases were studied by light and electron microscopy. Occlusion of the feeder arteriole and capillaries, and numerous vacuoles of variou...

journal_title：Japanese journal of ophthalmology

authors： Murata M,Yoshimoto H

更新日期：1983-01-01 00:00:00

abstract：:Experimental melanin-protein induced uveitis (EMIU) is a CD4 T cell-mediated disease involving the choroid and iris, but sparing the retina. The present study was designed to solubilize uveitogenic antigen from melanin granules without enzymatic digestion, and to investigate some of its elements by comparison with dif...

journal_title：Japanese journal of ophthalmology

authors： Broekhuyse RM,Kuhlmann ED,Winkens HJ

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:Remodeling of the extracellular matrix occurs in the lamina cribrosa in progressed glaucomatous optic nerve damage including disc cupping. We examined immunohistochemical changes in the transforming growth factor (TGF)-beta and platelet-derived growth factor (PDGF) in the optic nerve head in an experimentally i...

journal_title：Japanese journal of ophthalmology

authors： Fukuchi T,Ueda J,Hanyu T,Abe H,Sawaguchi S

更新日期：2001-11-01 00:00:00

abstract：:Purpose: We have developed a new method for quantification of metamorphopsia and applied it to study distorted vision resulting from epiretinal membrane (ERM).Patients and Methods: We prepared a modified Amsler chart, which was a square grid formed by black lines on a white background with 12 cm on a side and divided ...

journal_title：Japanese journal of ophthalmology

authors： Shinoda K,Ishida S,Kawashima S,Matsuzaki T,Yamada K,Katsura H

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:To verify the possibility that preoperative topical antibiotics are not essential as long as iodine disinfection is performed during surgery. STUDY DESIGN:Crossover equivalence trial. PATIENTS AND METHODS:In 204 eyes of 102 patients who underwent routine bilateral cataract surgery, 1 eye was treated with intr...

journal_title：Japanese journal of ophthalmology

authors： Matsuura K,Miyazaki D,Sasaki SI,Inoue Y,Sasaki Y,Shimizu Y

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:To describe the epidemiology and clinical outcomes of open globe injuries (OGIs) in Japan over 10 years, and examine preoperative factors influencing the visual prognosis after surgery. STUDY DESIGN:Retrospective, observational, multicenter case-series study. METHODS:Patients' data were entered into a compute...

journal_title：Japanese journal of ophthalmology

authors： Okamoto Y,Morikawa S,Okamoto F,Inomoto N,Ishikawa H,Ueda T,Sakamoto T,Sugitani K,Oshika T

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To evaluate the cycloplegic effect of mixed eye drops containing 0.5% tropicamide and 0.5% phenylephrine in myopic children, and to determine whether their efficacy was associated with their clinical characteristics. METHODS:Eighty-one myopic children (age, mean +/- SD, 11.0 +/- 1.5 years; mean spherical equiv...

journal_title：Japanese journal of ophthalmology

authors： Hamasaki I,Hasebe S,Kimura S,Miyata M,Ohtsuki H

更新日期：2007-03-01 00:00:00

abstract：:Photopic electroretinograms (ERGs) elicited with red or white flashes of various intensities under a bright background light were recorded in 119 eyes of 77 diabetic patients and 19 normal control eyes. The implicit time and amplitude of photopic ERGs were analyzed in relation to the stage of diabetic retinopathy, ie,...

journal_title：Japanese journal of ophthalmology

authors： Satoh S,Iijima H,Imai M,Abe K,Shibuya T

更新日期：1994-01-01 00:00:00

abstract：:A case of unilateral disc-shaped cataract with coloboma of the lens is reported. The patient, a 17-year-old girl, had best corrected visual acuity of 0.01 (+ 9 D) in the right eye and 1.2 in the left eye. Exotropia of 10 Hirschberg degrees was found in her right eye. The visual disturbance of that eye was thought to b...

journal_title：Japanese journal of ophthalmology

authors： Kihara Y,Shimomura Y,Omoto T,Fukuda M

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To elucidate the current clinical practice patterns of branch retinal vein occlusion (BRVO) management by retina specialists in Japan in the era of anti-vascular endothelial growth factor (VEGF) therapy. STUDY DESIGN:A voting survey using an answer pad system. METHODS:On May 28, 2017, forty-one retina special...

journal_title：Japanese journal of ophthalmology

authors： Ogura Y,Kondo M,Kadonosono K,Shimura M,Kamei M,Tsujikawa A

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To evaluate the effectiveness of the isolated caruncular approach to orbital decompression of thyroid ophthalmopathy. METHODS:In a retrospective, noncomparative, interventional case series, we reviewed the records of 29 patients (48 orbits) who had thyroid ophthalmopathy and had undergone orbital decompression...

journal_title：Japanese journal of ophthalmology

authors： Woo KI,Kim YD

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:To identify any possible determinants in the development of uveitis in leprosy patients. METHODS:Human leukocyte antigen (HLA) class I and II antigen, and HLA class II genotypings were analyzed among Japanese leprosy patients. Ninety-three unrelated Japanese leprosy patients (46 patients with a history of uvei...

journal_title：Japanese journal of ophthalmology

authors： Joko S,Numaga J,Maeda H

更新日期：1999-03-01 00:00:00

abstract：PURPOSE:Changes in optic disc and peripapillary structures associated with optic nerve edema in idiopathic intracranial hypertension (IIH), can be evaluated with spectral domain optical coherence tomography (SD-OCT). We aimed to evaluate the association between increased cerebrospinal fluid (CSF) opening pressure and c...

journal_title：Japanese journal of ophthalmology

authors： Bingöl Kızıltunç P,Atilla H

更新日期：2021-01-09 00:00:00

abstract：PURPOSE:To investigate the process of repair in the epithelial cells and the reconstruction in lens fibers of a mouse lens that has developed opacity because of a large-scale perforating injury. METHODS:Lenses of 4-week-old mice were perforated with a needle through the cornea to induce the development of traumatic ca...

journal_title：Japanese journal of ophthalmology

authors： Hirayama S,Wakasugi A,Morita T,Sakai Y,Mukuno K,Uga S,Shimizu K

更新日期：2003-07-01 00:00:00

abstract：:A surgically obtained lens from a 66-year-old man with the Weill-Marchesani syndrome was examined histopathologically by light microscopy, transmission electron microscopy and scanning electron microscopy. The lens was diffusely opaque and brown. It was microspherophakic in appearance, 6.0 mm in equatorial diameter an...

journal_title：Japanese journal of ophthalmology

authors： Nagata M,Takagi S,Yamasaki A,Tsunematsu S,Kumagami T,Itamochi C,Tamai A

更新日期：1995-01-01 00:00:00