Ocular changes in a limited form of Wegener's granulomatosis: patient with cutaneous ulcer of upper eyelid.

Abstract:

BACKGROUND:We report a patient with a limited form of Wegener's granulomatosis (WG) who presented with ocular changes and an eyelid ulcer in her left eye. CASE:A 56-year-old woman complained of ocular pain and discharge. Upon examination, we found evidence of ulcerative keratitis, a mass in the orbit, and an eyelid skin ulcer in her left eye. OBSERVATIONS:The antineutrophil cytoplasmic antibody test was negative, and systemic evaluations showed no specific changes. A biopsy specimen of the left orbit demonstrated necrosis, granulomatous inflammation, and vasculitis. A diagnosis was made of a limited form of WG, whilethe biopsy specimen of the left upper lid demonstrated granulomatous inflammation without vasculitis. CONCLUSION:Although the eyelid ulcer was contiguous with the orbital mass, histopathology showed they had distinctive pathological features.

journal_name

Jpn J Ophthalmol

authors

Kubota T,Hirose H

doi

10.1016/s0021-5155(03)00078-9

keywords:

subject

Has Abstract

pub_date

2003-07-01 00:00:00

pages

398-400

issue

4

eissn

0021-5155

issn

1613-2246

pii

S0021515503000789

journal_volume

47

pub_type

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