当前位置： SCI文献检索 > JAPANESE JOURNAL OF OPHTHALMOLOGY期刊下所有文献 > Comparison of two different spectral domain optical coherence tomography devices in the detection of localized retinal nerve fiber layer defects.

Comparison of two different spectral domain optical coherence tomography devices in the detection of localized retinal nerve fiber layer defects.

Abstract：

PURPOSE:To compare the detection of localized retinal nerve fiber layer (RNFL) defects by two different spectral domain optical coherence tomography (SD-OCT) devices. METHODS:Eyes of 42 normal control subjects and 48 patients with a localized RNFL defect on red-free fundus photographs were imaged by the Cirrus (Carl Zeiss Meditec, Dublin, CA, USA) and 3D OCT (Topcon, Tokyo, Japan) devices. We compared sensitivities, specificities, and area under the receiver operating characteristic curves (AUCs) of circumpapillary RNFL (cpRNFL) thickness and ganglion cell complex (GCC) parameters between the two devices. RESULTS:The devices provided different cpRNFL thickness measurements. The highest sensitivities at fixed specificities of 80 % (Cirrus: 83.3 %; 3D OCT: 77.1 %) and 95 % (Cirrus: 69.8 %; 3D OCT: 68.8 %) and the largest AUCs (Cirrus: 0.90; 3D OCT: 0.88) obtained by the cpRNFL parameters of the two devices were similar. Based on the internal normative database, the deviation-from-normal map of the Cirrus OCT device and the 36-segment map of the 3D OCT device had the highest sensitivity (89.6 and 91.7 %, respectively). Among the macular GCC parameters of the 3D OCT device, inferior macular RNFL thickness had the highest sensitivity (81.2 % at a specificity of 80 %) and the largest AUC (0.89). CONCLUSIONS:Although the two SD-OCT devices have different measurement protocols, they showed similar abilities for the detection of a localized RNFL defect.

journal_name

Jpn J Ophthalmol

journal_title

Japanese journal of ophthalmology

authors

Kim KE,Ahn SJ,Kim DM

doi

10.1007/s10384-013-0239-7

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

347-58

issue

4

eissn

0021-5155

issn

1613-2246

journal_volume

57

pub_type

杂志文章

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