Morphological observations of rat corneal endothelial cells after exposure to ozonated solution.

abstract：PURPOSE:To determine the morphological characteristics of the cornea in eyes with posterior corneal vesicles (PCV) determined by in vivo confocal microscopy (IVCM). In addition, to compare the morphological characteristics of the corneas of eyes with PCV to those of eyes with posterior polymorphous corneal dystrophy (P...

journal_title：Japanese journal of ophthalmology

authors： Shiraishi A,Zheng X,Sakane Y,Hara Y,Hayashi Y

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:To compare endothelial damage of the donor cornea in relation to the method of inserting the donor cornea into the recipient anterior chamber during Descemet-stripping automated endothelial keratoplasty (DSAEK). METHODS:Fifteen enucleated pig eyes were used. The donor corneoscleral buttons were mounted in an a...

journal_title：Japanese journal of ophthalmology

authors： Hwang H,Kim M

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:To investigate the differences in thickness and depth of the lamina cribrosa (LC) between ocular hypertension (OH) patients and normal control subjects, using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (SD-OCT). METHODS:EDI-OCT data were obtained from the subjects in a cross-sect...

journal_title：Japanese journal of ophthalmology

authors： Han JC,Choi DY,Kwun YK,Suh W,Kee C

更新日期：2016-01-01 00:00:00

abstract：:The ocular penetration of two beta-adrenergic blockers, befunolol and timolol, was studied using albino and pigmented rabbits. A 1% ophthalmic solution of 14C-befunolol hydrochloride or 14C-timolol maleate was instilled in one eye of nonsedated rabbits, and the concentrations of radioactive material in the ocular tiss...

journal_title：Japanese journal of ophthalmology

authors： Araie M,Takase M,Sakai Y,Ishii Y,Yokoyama Y,Kitagawa M

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:We have found that two aspartyl (Asp-151 and Asp-58) residues of alphaA-crystallin are inverted and isomerized to the biologically uncommon D-beta-Asp residues during aging. In order to elucidate the correlation between the formation of the D-beta-Asp isomer and the environment surrounding the Asp in the protei...

journal_title：Japanese journal of ophthalmology

authors： Mizuno A,Fujii N,Akaboshi M,Momose Y,Shimo-oka T

更新日期：2000-07-01 00:00:00

abstract：PURPOSE:To determine whether the single-flash electroretinogram (ERG) can predict the postoperative outcome in diabetic cases where massive vitreous hemorrhage precludes fundus observation. METHODS:Eighty-five diabetic patients (105 eyes) who underwent vitrectomy due to dense vitreous hemorrhage were studied retrospec...

journal_title：Japanese journal of ophthalmology

authors： Hiraiwa T,Horio N,Terasaki H,Suzuki T,Yamamoto E,Horiguchi M,Miyake Y

更新日期：2003-05-01 00:00:00

abstract：PURPOSE:The purpose of this study was to estimate the optimal size of visual field test for detecting longitudinal changes in retinitis pigmentosa (RP) by dividing the visual field. METHODS:We reviewed the results of 10° static visual field tests in 19 eyes of 19 RP patients. Sixty-eight numeric value points were divi...

journal_title：Japanese journal of ophthalmology

authors： Ogino K,Otani A,Oishi A,Kurimoto M,Sekiya T,Yoshimura N

更新日期：2013-05-01 00:00:00

abstract：:Clinical, pathological and follow-up data on the 1,147 cases of retinoblastoma registered in Japan from 1975 to 1982 were statistically analyzed. The cumulative survival rate of the total 1,147 cases was 93.0% at 5 years and 90.3% at 10 years, calculated by the Kaplan-Meier method. The survival rate for the 757 unilat...

journal_title：Japanese journal of ophthalmology

authors：

更新日期：1992-01-01 00:00:00

abstract：:The authors experienced one case of malignant melanoma of the superior palpebral conjunctiva and the inferior palpebral skin, originating from benign acquired melanosis of the bulbar conjunctiva which developed in a 48-year-old man. Orbital exenteration including superior and inferior palpebrae was performed, and the ...

journal_title：Japanese journal of ophthalmology

authors： Ueno H,Tamai A,Noda K,Kishi S,Iyota K,Masaoka N,Wada H

更新日期：1983-01-01 00:00:00

abstract：:The glycocalyx, present on the surface of the corneal epithelium, contains sialoglycoconjugates. The developmental change in the sialylated residues may be evaluated by examining the expression of the sialyltransferase mRNA. We examined the distribution of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase mRNA in rat cor...

journal_title：Japanese journal of ophthalmology

authors： Uehara F,Ozawa M,Iwakiri N,Ohba N

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:To investigate the role of mechanical stretch in the regulation of matrix metalloproteinase-2 (MMP-2) in scleral fibroblasts of chick embryos. METHODS:Scleral fibroblasts derived from chick embryos were seeded onto flexible bottom culture plates, and subjected to a pulsatile stretch when the cells became subco...

journal_title：Japanese journal of ophthalmology

authors： Fujikura H,Seko Y,Tokoro T,Mochizuki M,Shimokawa H

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:Comparison of anterior chamber angle measurements using ultrasound biomicroscopy (UBM) and gonioscopy. METHODS:Five hundred subjects were evaluated for grading of angle width by the Shaffer method. UBM was done in the same group to document angle width, angle opening distance (AOD 500), and anterior chamber de...

journal_title：Japanese journal of ophthalmology

authors： Narayanaswamy A,Vijaya L,Shantha B,Baskaran M,Sathidevi AV,Baluswamy S

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:The involvement of cytokines and chemokines in vitreous fluid is important in the development and progression of diabetic retinopathy (DR) and central retinal vein occlusion (CRVO). In this study, the concentrations of cytokines and chemokines in the vitreous fluid of eyes with DR and CRVO were measured and com...

journal_title：Japanese journal of ophthalmology

authors： Suzuki Y,Nakazawa M,Suzuki K,Yamazaki H,Miyagawa Y

更新日期：2011-05-01 00:00:00

abstract：:We assessed the function of Endothelin-1 (ET-1) in the development of anterior chamber inflammation in pigmented rabbit eyes. After the injection of ET-1 solution (10(-13), 10(-11), 10(-9), or 10(-7) M, diluted with 300 microL of artificial aqueous humor) into the anterior chamber, the aqueous protein concentration (A...

journal_title：Japanese journal of ophthalmology

authors： Shoji N,Oshika T,Masuda K

更新日期：1997-05-01 00:00:00

abstract：PURPOSE:It is well-known that patients with psychogenic visual disturbances (PVD) exhibit characteristic kinetic visual fields. Even when the kinetic fields are normalized, the static fields of PVD children frequently remain abnormal. To verify this finding, we performed static perimetry on those children whose kinetic...

journal_title：Japanese journal of ophthalmology

authors： Osako M,Harasawa K,Suzuki H,Usui M,Hoshika A

更新日期：2000-09-01 00:00:00

abstract：:The superior colliculus (SC) plays an important role in the transformation of visual and auditory signals into motor commands to generate saccadic eye movements toward the targets. This study investigated the synaptic input patterns from the SC, into vertical eye movement-related superior and inferior rectus motoneuro...

journal_title：Japanese journal of ophthalmology

authors： Sasaki Y,Matsui H,Tamai A

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:To determine whether photoreceptor degeneration in transgenic (Tg) rabbits carrying the Pro347Leu rhodopsin mutation alters the neural activity of the middle and inner retinal neurons. METHODS:Multifocal electroretinograms (mfERGs) were recorded from eight 12-week-old Tg rabbits both before and after intravitr...

journal_title：Japanese journal of ophthalmology

authors： Yokoyama D,Machida S,Kondo M,Terasaki H,Nishimura T,Kurosaka D

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:The aqueous humor (AH) contains numerous immunosuppressive molecules that contribute to the ocular immune privilege. Here, we mimic an inflammatory environment to analyze the inhibitory effects of the AH on lipopolysaccharide (LPS)-induced maturation of dendritic cells (DC). METHODS:Different concentrations of...

journal_title：Japanese journal of ophthalmology

authors： Wang HF,Liu JL,Jiang XL,Lu JM,Li XL,Song XJ

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Vogt-Koyanagi-Harada (VKH) disease patients with the complication of subretinal pigmented proliferative tissue tend to have a poor visual prognosis. CASE:We herein report a case of VKH with good visual acuity despite a prominent subretinal fold. OBSERVATIONS:A 24-year-old woman, who experienced several rec...

journal_title：Japanese journal of ophthalmology

authors： Noda Y,Sonoda KH,Nakamura T,Kawano YI,Ishibashi T,Inomata H

更新日期：2003-11-01 00:00:00

abstract：:Human lens epithelial cells (HLECs) with lens capsules were cultured to investigate the morphology and outgrowth potential of the cultured cells. Anterior lens capsules obtained during cataract surgery were placed cell side down in a medium in culture wells. Cultivation was successful with 24 of 36 specimens from seni...

journal_title：Japanese journal of ophthalmology

authors： Ibaraki N,Ohara K,Shimizu H

更新日期：1993-01-01 00:00:00

abstract：:We investigated the ocular fundus of (NZWXBXSB) F1 mice, which are considered to be a good model for systemic lupus erythematosus (SLE) with antiphospholipid syndrome. The abnormal fundus findings were documented by fundus photography, and the chorioretinal lesions were studied histopathologically. The incidence of oc...

journal_title：Japanese journal of ophthalmology

authors： Nakamura A,Yokoyama T,Kodera S,Zhang D,Hirose S,Shirai T,Kanai A

更新日期：1998-09-01 00:00:00

abstract：PURPOSE:To clarify the redox states of the aqueous humor and serum in senile cataract patients. METHODS:We analyzed the reduced and oxidized albumin fractions in 58 patients. The patients had no detectable evidence of other eye or systemic diseases and were divided into two age groups (53-75 and 76-96 years). Analysis...

journal_title：Japanese journal of ophthalmology

authors： Kawai K,Hayashi T,Matsuyama Y,Minami T,Era S

更新日期：2010-11-01 00:00:00

abstract：:The clinical characteristics of 20 eyes of 20 consecutive patients with traumatic macular hole were studied retrospectively. The macular holes were elliptical with irregular edges in 19 eyes (95%) and ranged in size from 0.2 to 0.5 DD (disc diameter). Posterior vitreous detachment (PVD) was found in only 3 eyes (15%);...

journal_title：Japanese journal of ophthalmology

authors： Yanagiya N,Akiba J,Takahashi M,Shimizu A,Kakehashi A,Kado M,Hikichi T,Yoshida A

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:To assess intravitreal bevacizumab (IVB) for choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) in Japanese patients. METHODS:Forty-seven patients treated with IVB for newly diagnosed subfoveal or juxtafoveal CNV (predominantly classic CNV, 15 eyes; minimally classic CNV, 11...

journal_title：Japanese journal of ophthalmology

authors： Suzuki M,Gomi F,Sawa M,Tsujikawa M,Sakaguchi H

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:To study the effect of cyclosporin (CsA) on steroid-induced cataracts in patients following renal transplantation. METHODS:The subjects comprise 140 patients who had undergone renal transplantation at Kanazawa Medical Hospital. These subjects had received ophthalmologic examinations prior to their surgery and ...

journal_title：Japanese journal of ophthalmology

authors： Nakamura T,Sasaki H,Nagai K,Fujisawa K,Sasaki K,Suzuki K,Tsugawa R

更新日期：2003-05-01 00:00:00

abstract：:We evaluated postoperative binocularity in a retrospective study of 111 adult strabismus patients in order to identify the factors which influence the success of surgery for horizontal concomitant strabismus in adults. Selection criteria included minimum age of 15 years at time of surgery, and preoperative fusion impa...

journal_title：Japanese journal of ophthalmology

authors： Umazume F,Ohtsuki H,Hasebe S

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:Full-thickness macular holes usually develop in the elderly population. To the best of our knowledge, there has been no written report of a nontraumatic macular hole in a pediatric patient. CASE:A 10-year-old girl noticed decreased central vision in her left eye without any history of trauma. OBSERVATIONS:...

journal_title：Japanese journal of ophthalmology

authors： Nakano T,Uemura A,Kanda S,Sakamoto T

更新日期：2005-11-01 00:00:00

abstract：:We examined ophthalmologically five affected members of a family with type IIa hyperlipoproteinemia. All of them had increased levels of cholesterol and low-density lipoprotein. Corneal arcus was found in three of the five members; a 50-year-old man, a 43-year-old woman and a 13-year-old boy. We believe that the corne...

journal_title：Japanese journal of ophthalmology

authors： Hayasaka S,Honda M,Kitaoka M,Chiba R

更新日期：1984-01-01 00:00:00

abstract：PURPOSE:To report optical coherence tomography (OCT) findings of macular edema secondary to retinal arterial macroaneurysms. METHODS:Six eyes with retinal arterial macroaneurysms were retrospectively examined by OCT. All eyes had macular edema without massive macular hemorrhage. Fluorescein angiography was performed i...

journal_title：Japanese journal of ophthalmology

authors： Takahashi K,Kishi S

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:To investigate the predictive factors of polyp regression after intravitreal ranibizumab injections for polypoidal choroidal vasculopathy (PCV). METHODS:Sixty-nine eyes (69 patients) with treatment-naïve PCV received an initial series of 3-monthly intravitreal ranibizumab injections, followed by as-needed inje...

journal_title：Japanese journal of ophthalmology

authors： Cho HJ,Han SY,Kim HS,Lee TG,Kim JW

更新日期：2015-01-01 00:00:00