Clinical characteristics of traumatic macular holes.

abstract：:We reported previously familial hypo-retinol-binding proteinemia in a child who developed keratomalacia during measles infection. In the present study, we characterized serum retinol-binding proteins (RBPs) in the affected family members and compared these RBPs with those in the unaffected family members. Immunoblotti...

journal_title：Japanese journal of ophthalmology

authors： Matsuo T,Matsuo N

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To investigate whether retinal glial cells (RGCs), which are believed to play an important role in the development and maintenance of microvessels, stimulate the proliferation of retinal bovine microvascular pericytes, an essential component of the vessels. METHODS:Conditioned medium (CM) was collected from a ...

journal_title：Japanese journal of ophthalmology

authors： Ikuno Y,Hibino S,Bando H,Kawasaki Y,Nakamura T,Tano Y

更新日期：2002-07-01 00:00:00

abstract：:The ocular penetration of two beta-adrenergic blockers, befunolol and timolol, was studied using albino and pigmented rabbits. A 1% ophthalmic solution of 14C-befunolol hydrochloride or 14C-timolol maleate was instilled in one eye of nonsedated rabbits, and the concentrations of radioactive material in the ocular tiss...

journal_title：Japanese journal of ophthalmology

authors： Araie M,Takase M,Sakai Y,Ishii Y,Yokoyama Y,Kitagawa M

更新日期：1982-01-01 00:00:00

abstract：:The enzyme 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNPase) is one of the important markers for myelin synthesis or demyelination. We measured the CNPase activities in the visual pathway tissues of Lewis strain rats with experimental allergic encephalomyelitis (EAE) induced by inoculation of myelin basic protein f...

journal_title：Japanese journal of ophthalmology

authors： Matsushima S,Machi N,Marumo M,Mizuno A

更新日期：1986-01-01 00:00:00

abstract：:Histochemical studies were carried out in the mouse on the changes and distribution patterns of glycosaminoglycan molecular species during the separation of the lens vesicle. To obtain embryos, pregnant mice of the Jcl:ICR strain were sacrificed on day 10.5 or 11 of pregnancy. Serial frontal sections were strained wit...

journal_title：Japanese journal of ophthalmology

authors： Mizuno S,Ikeda K,Hirabayashi Y

更新日期：1995-01-01 00:00:00

abstract：:The motoneurons innervating the musculus levator palpebrae superioris (LPS) of the monkey, the cat and the rabbit were studied using horseradish peroxidase (HRP). Furthermore, LPS motoneurons of the cat and rabbit were studied by the double-labeling method using two fluorescent dyes as retrograde neuronal tracers. Aft...

journal_title：Japanese journal of ophthalmology

authors： Hiramoto D,Sekiya H,Kojima Y,Mukuno K,Ishikawa S

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:To compare the visualization of microaneurysms (MAs) in patients with diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA) with that using fluorescein angiography (FA). STUDY DESIGN:Prospective, clinical, and experimental. METHODS:This study was a prospective evaluation of imaging t...

journal_title：Japanese journal of ophthalmology

authors： Hamada M,Ohkoshi K,Inagaki K,Ebihara N,Murakami A

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To evaluate the degree of ischemia in eyes with retinal vein occlusion (RVO) using swept-source optical coherence tomography angiography (SS-OCTA) with the extended field imaging (EFI) technique, which extends the area encompassed by SS-OCTA by scanning through trial frames fitted with a +20-diopter lens. STUD...

journal_title：Japanese journal of ophthalmology

authors： Kakihara S,Hirano T,Iesato Y,Imai A,Toriyama Y,Murata T

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To perform a retrospective study to evaluate the long-term outcome of systemic cyclosporine treatment as an adjunct to topical corticosteroid treatment after penetrating keratoplasty (PKP). METHODS:Twenty-six high-risk patients (27 eyes) who received systemic cyclosporine following PKP for an average of 5.4 mo...

journal_title：Japanese journal of ophthalmology

authors： Inoue K,Kimura C,Amano S,Sato T,Fujita N,Kagaya F,Kaji Y,Tsuru T,Araie M

更新日期：2001-07-01 00:00:00

abstract：PURPOSE:To compare the outcome of early treatment at the initial stage 3 moderate phase of retinopathy of prematurity (ROP) with that at prethreshold ROP. METHODS:The outcome of treatment of 117 very-low-birth-weight infants was reviewed. Sixty-eight infants underwent their first treatment at prethreshold ROP (group A...

journal_title：Japanese journal of ophthalmology

authors： Hatsukawa Y,Ueki N,Yamagishi T,Kitajima H

更新日期：2005-09-01 00:00:00

abstract：:It has been reported that keratocytes endocytose foreign particles both in vitro and in vivo, suggesting the active participation of keratocytes in corneal wound healing and host defense mechanism. To understand the cellular response and the fate of engulfed foreign particles, we investigated the changes in the lysoso...

journal_title：Japanese journal of ophthalmology

authors： Mishima H,Ueda A,Nishida T,Otori T

更新日期：1992-01-01 00:00:00

abstract：:A newly developed model of keratoepithelioplasty (KEP) in the rat was used to analyze the effect of anterior chamber-associated immune deviation on the suppression of corneal allograft rejection. The right eyes of Fisher rats received an anterior chamber (AC) injection of lymphocyte suspension from Dark Agouti (DA) ra...

journal_title：Japanese journal of ophthalmology

authors： Yao YF,Inoue Y,Hara Y,Kiritoshi A,Tano Y,Ohashi Y

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:To identify any possible determinants in the development of uveitis in leprosy patients. METHODS:Human leukocyte antigen (HLA) class I and II antigen, and HLA class II genotypings were analyzed among Japanese leprosy patients. Ninety-three unrelated Japanese leprosy patients (46 patients with a history of uvei...

journal_title：Japanese journal of ophthalmology

authors： Joko S,Numaga J,Maeda H

更新日期：1999-03-01 00:00:00

abstract：PURPOSE:To evaluate the functional surgical success, complications, and degree of satisfaction after endoscopy-guided transcaruncular Jones tube intubation without dacryocystorhinostomy (DCR). METHODS:A pair of Westcott scissors was passed into the nose from the side of the caruncle, and the lacrimal bone was penetrat...

journal_title：Japanese journal of ophthalmology

authors： Choi WC,Yang SW

更新日期：2006-03-01 00:00:00

abstract：PURPOSE:To evaluate the effects of topical latanoprost and timolol in combined therapy on retinal blood flow and tissue circulation in the optic nerve head (ONH) of the cynomolgus monkey. METHODS:Latanoprost (30 microL, 0.005%) was instilled once daily and timolol (30 microL, 0.5%) twice daily for 6 days into 1 eye, a...

journal_title：Japanese journal of ophthalmology

authors： Ishii K,Araie M

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:To assess intravitreal bevacizumab (IVB) for choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) in Japanese patients. METHODS:Forty-seven patients treated with IVB for newly diagnosed subfoveal or juxtafoveal CNV (predominantly classic CNV, 15 eyes; minimally classic CNV, 11...

journal_title：Japanese journal of ophthalmology

authors： Suzuki M,Gomi F,Sawa M,Tsujikawa M,Sakaguchi H

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Schwannoma arising from the ciliary body is a rare intraocular neoplasm, and most cases previously reported were diagnosed histopathologically after eyeball enucleation because of a diagnosis of ciliary body melanoma. CASE:A case of ciliary body schwannoma was dissected locally. OBSERVATIONS:A 19-year-old ...

journal_title：Japanese journal of ophthalmology

authors： Goto H,Mori H,Shirato S,Usui M

更新日期：2006-11-01 00:00:00

abstract：PURPOSE:To report on isolated central retinal artery occlusion (CRAO) as an initial presentation in two patients with undiagnosed paroxysmal nocturnal hemoglobinuria (PNH). METHODS:CRAO related to the aggravation of PNH was observed in 2 of 98 consecutive PNH patients for 10 years. Ocular and systemic manifestations w...

journal_title：Japanese journal of ophthalmology

authors： Yang HS,Park SH,Choi JR,Kim JG

更新日期：2013-09-01 00:00:00

abstract：:A surgically obtained lens from a 66-year-old man with the Weill-Marchesani syndrome was examined histopathologically by light microscopy, transmission electron microscopy and scanning electron microscopy. The lens was diffusely opaque and brown. It was microspherophakic in appearance, 6.0 mm in equatorial diameter an...

journal_title：Japanese journal of ophthalmology

authors： Nagata M,Takagi S,Yamasaki A,Tsunematsu S,Kumagami T,Itamochi C,Tamai A

更新日期：1995-01-01 00:00:00

abstract：:Severe, white sheathing of the retinal vessels and yellowish-white placoid lesions, suggesting frosted-branch angiitis, were found in both fundi of a 24-year-old woman. Fluorescein angiography showed hypofluorescence of the placoid lesions in the early phase and hyperfluorescence in the late phase. Indocyanine green a...

journal_title：Japanese journal of ophthalmology

authors： Masuda K,Ueno M,Watanabe I

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Interferon alpha-2b (IFN alpha 2b) was recently shown to be effective as an alternative therapy for conjunctival intraepithelial neoplasia (CIN). Herein, we report our successful management of CIN by the use of IFN alpha 2b. CASE:A 73-year-old woman presented with a complaint of irritation due to a tumorous...

journal_title：Japanese journal of ophthalmology

authors： Kobayashi A,Yoshita T,Uchiyama K,Shirao Y,Kitagawa K,Fujisawa A,Tseng SC

更新日期：2002-03-01 00:00:00

abstract：:A 25-year-old woman is described whose clinical features included infantile hypotonia, obesity after infancy, intellectual impairment, dysmorphic facial features, short stature, small hands and feet, and abnormal dentition, which are typical of the Prader-Willi syndrome. The patient had almond-shaped eyes, spot-like h...

journal_title：Japanese journal of ophthalmology

authors： Wang XC,Norose K,Kiyosawa K,Segawa K

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:Novel spectacle lenses (MyoVision, Carl Zeiss) designed to reduce relative peripheral hyperopia have been developed and reported to be effective for preventing myopia progression in a subgroup of Chinese children. In this study we examined the efficacy of MyoVision lenses in Japanese children. STUDY DESIGN:Thi...

journal_title：Japanese journal of ophthalmology

authors： Kanda H,Oshika T,Hiraoka T,Hasebe S,Ohno-Matsui K,Ishiko S,Hieda O,Torii H,Varnas SR,Fujikado T

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:Lysophosphatidic acid (LPA), which activates the small guanosine triphosphate (GTP)-binding protein Rho, was previously shown to promote migration of the rabbit corneal epithelium in culture. The signaling pathway responsible for this effect of LPA was examined in this study with a human corneal epithelial (HCE...

journal_title：Japanese journal of ophthalmology

authors： Saito J,Morishige N,Chikama T,Gu J,Sekiguchi K,Nishida T

更新日期：2004-05-01 00:00:00

abstract：PURPOSE:To estimate the melatonin suppression index (MSI), which may reflect the nonvisual photoreception function, through commercially available foldable, clear and yellow-tinted intraocular lenses (IOLs). METHODS:The MSIs for 13 IOL models (6 clear IOLs, 7 yellow-tinted IOLs) with three lens powers were calculated ...

journal_title：Japanese journal of ophthalmology

authors： Sano I,Tanito M,Okuno T,Ishiba Y,Ohira A

更新日期：2014-07-01 00:00:00

abstract：:Human lens epithelial cells (HLECs) with lens capsules were cultured to investigate the morphology and outgrowth potential of the cultured cells. Anterior lens capsules obtained during cataract surgery were placed cell side down in a medium in culture wells. Cultivation was successful with 24 of 36 specimens from seni...

journal_title：Japanese journal of ophthalmology

authors： Ibaraki N,Ohara K,Shimizu H

更新日期：1993-01-01 00:00:00

abstract：:Movement of fluorescein and fluorescein glucuronide, a fluorescent metabolite of fluorescein, across the isolated iris-ciliary body of the albino rabbit was determined under short-circuit conditions using a modified Ussing's chamber. The permeabilities of this tissue to these dyes were calculated. The outward permeabi...

journal_title：Japanese journal of ophthalmology

authors： Eguchi S,Araie M,Takase M

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:Changes in optic disc and peripapillary structures associated with optic nerve edema in idiopathic intracranial hypertension (IIH), can be evaluated with spectral domain optical coherence tomography (SD-OCT). We aimed to evaluate the association between increased cerebrospinal fluid (CSF) opening pressure and c...

journal_title：Japanese journal of ophthalmology

authors： Bingöl Kızıltunç P,Atilla H

更新日期：2021-01-09 00:00:00

abstract：PURPOSE:To compare the progression of posterior vitreous detachment (PVD) during aging among eyes of diabetics with diabetic retinopathy (DR), eyes of diabetics without DR, and eyes of nondiabetics. STUDY DESIGN:Prospective cross-sectional study. METHODS:One-hundred thirty-three diabetic eyes with DR (DR group), 254 ...

journal_title：Japanese journal of ophthalmology

authors： Hayashi K,Sato T,Manabe SI,Hirata A,Yoshimura K

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:To evaluate the repeatability of corneal deformation parameters measured using a dynamic Scheimpflug analyzer and the impact of baseline clinical factors on the repeatability of each parameter. STUDY DESIGN:Retrospective, cross-sectional study. METHODS:Forty-eight eyes (48 healthy subjects; mean age, 49.0 ± 1...

journal_title：Japanese journal of ophthalmology

authors： Miki A,Maeda N,Asai T,Ikuno Y,Nishida K

更新日期：2017-11-01 00:00:00