Long-term outcome of systemic cyclosporine treatment following penetrating keratoplasty.

abstract：:Purpose: We investigated the relationship between the progression of visual field defect and clinical factors in patients with normal-tension glaucoma (NTG).Subjects and Methods: Forty-eight eyes of 48 NTG patients undergoing more than 5-year follow-up were enrolled in this study. Their visual field defects ranged bet...

journal_title：Japanese journal of ophthalmology

authors： Tanaka C,Yamazaki Y,Yokoyama H

更新日期：2001-01-01 00:00:00

abstract：:Human lens epithelial cells (HLECs) with lens capsules were cultured to investigate the morphology and outgrowth potential of the cultured cells. Anterior lens capsules obtained during cataract surgery were placed cell side down in a medium in culture wells. Cultivation was successful with 24 of 36 specimens from seni...

journal_title：Japanese journal of ophthalmology

authors： Ibaraki N,Ohara K,Shimizu H

更新日期：1993-01-01 00:00:00

abstract：:The usefulness of the Fluorotron Master fluorophotometer fitted with a small animal adapter was evaluated with tree shrews. We also determined that the optimal measurement parameters for these animals, which are regarded as promising for experimental use in ophthalmic research, are: fluorescein-Na concentration, 0.5 x...

journal_title：Japanese journal of ophthalmology

authors： Ishiko S,Yoshida A,Kitaya N,Abiko T,Mori F,Kado M,Takahashi M,Saito K

更新日期：1996-01-01 00:00:00

abstract：:Fluoroquinolones provide an important single antibiotic therapy for bacterial keratitis caused by Staphylococcus aureus and numerous gram-negative bacteria, including Pseudomonas aeruginosa. The pharmacokinetics of three ocular fluoroquinolones, norfloxacin (CHIBOXIN, Merck, Sharp & Dohme), ciprofloxacin (CILOXAN, Alc...

journal_title：Japanese journal of ophthalmology

authors： Green LC,Callegan MC,Engel LS,Shimomura Y,Jasheway DW,O'Callaghan RJ,Hill JM

更新日期：1996-01-01 00:00:00

abstract：:The effect of 3,3'-iminodipropionitrile (IDPN) on experimental intravitreal proliferation in albino rabbits was studied by light and electron microscopy. About 2.5 x 10(5) tissue cultured fibroblasts were injected into the vitreous cavity of albino rabbits. Immediately after the injection, phosphate-buffered solution ...

journal_title：Japanese journal of ophthalmology

authors： Akiyama K

更新日期：1990-01-01 00:00:00

abstract：:We explored the involvement of CD44 isoforms in lymphoproliferative disorder (LPD) of the lacrimal gland of a Sjögren's syndrome patient with unilateral LPD. The CD44 variant with the v6 exon was selectively detected from infiltrating lymphocytes in the gland with LPD, but not from infiltrating lymphocytes in the norm...

journal_title：Japanese journal of ophthalmology

authors： Hiraoka M,Saito I,Tsubota K,Sugai S,Miyasaka N

更新日期：1997-09-01 00:00:00

abstract：:Persistent bullous keratopathy was produced in one eye of a rabbit by anterior chamber irrigation with benzalkonium chloride solution (BAK). Corneal grafts were made from both eyes of another rabbit and they were transplanted to the eye with bullous keratopathy and the normal fellow eye, which served as the control. S...

journal_title：Japanese journal of ophthalmology

authors： Yang HJ,Sato T,Matsubara M,Tanishima T

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To verify the advantages of trabeculotomy combined with phacoemulsification, intraocular lens implantation and sinusotomy (PTOS) in eyes with exfoliation glaucoma (XFG) and a coexisting cataract. PATIENTS AND METHODS:Sixty-six eyes of 62 Japanese XFG patients that received either PTOS, phacotrabeculectomy (PTE...

journal_title：Japanese journal of ophthalmology

authors： Fukuchi T,Ueda J,Nakatsue T,Suda K,Hara H,Abe H

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To report three types of heterozygous mutations in the OPA1 gene in five patients from three families with autosomal dominant optic atrophy (ADOA, MIM#165500). METHODS:DNA was extracted from the leukocytes of the peripheral blood. For mtDNA, mutations were examined at positions 11778, 3460 and 14484. For the O...

journal_title：Japanese journal of ophthalmology

authors： Hamahata T,Fujimaki T,Fujiki K,Miyazaki A,Mizota A,Murakami A

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To evaluate axial length (AL) measurements and refractive outcomes in vitrectomy combined with cataract operation for rhegmatogenous retinal detachment (RRD) with wholly detached macula. STUDY DESIGN:Retrospective, consecutive, comparative, clinical study. METHODS:We reviewed the data of patients treated by v...

journal_title：Japanese journal of ophthalmology

authors： Pak KY,Park KH,Park SW,Byon IS,Lee JE

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To examine using the folds of the retinal pigment epithelium (RPE) to diagnose Vogt-Koyanagi-Harada (VKH) disease. METHODS:Retrospective clinical review of 57 Japanese patients between July 2005 and April 2009. Optical coherence tomography (OCT), fundus photographs and fluorescein angiography (FA) were studi...

journal_title：Japanese journal of ophthalmology

authors： Kato Y,Yamamoto Y,Tabuchi H,Fukushima A

更新日期：2013-01-01 00:00:00

abstract：:The authors experienced one case of malignant melanoma of the superior palpebral conjunctiva and the inferior palpebral skin, originating from benign acquired melanosis of the bulbar conjunctiva which developed in a 48-year-old man. Orbital exenteration including superior and inferior palpebrae was performed, and the ...

journal_title：Japanese journal of ophthalmology

authors： Ueno H,Tamai A,Noda K,Kishi S,Iyota K,Masaoka N,Wada H

更新日期：1983-01-01 00:00:00

abstract：:The exfoliation syndrome is thought to be a very rare disease in China. The clinical features of 11 patients with pseudoexfoliation (PE) and the histopathologic changes in specimens affected by PE were studied. The loss of pigment at the pupillary ruff and the dense pigmentation on the trabecular meshwork were the ear...

journal_title：Japanese journal of ophthalmology

authors： Ye TC,Mao WS,Zhang J

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:To determine whether the time course of average visual recovery (visual gain curve) after vitrectomy for different macular diseases can be described by a mathematical function. METHODS:The medical records of 1951 eyes that underwent vitrectomy for different macular diseases such as macular hole, epiretinal mem...

journal_title：Japanese journal of ophthalmology

authors： Kumagai K,Ogino N,Larson E

更新日期：2011-03-01 00:00:00

abstract：:The complexity of visual field result evaluation has increased with the advent of automated perimetry. This in turn makes software assistance such as provided by the new Octosmart program interesting and desirable. Its accuracy and reliability in visual field evaluation must be tested, though, and the testing methodol...

journal_title：Japanese journal of ophthalmology

authors： Hirsbrunner HP,Fankhauser F,Funkhouser AT,Jenni A

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To clarify the redox states of the aqueous humor and serum in senile cataract patients. METHODS:We analyzed the reduced and oxidized albumin fractions in 58 patients. The patients had no detectable evidence of other eye or systemic diseases and were divided into two age groups (53-75 and 76-96 years). Analysis...

journal_title：Japanese journal of ophthalmology

authors： Kawai K,Hayashi T,Matsuyama Y,Minami T,Era S

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:To assess the combined estimate of retinal ganglion cell (RGC) count developed by Medeiros et al. as a tool for diagnosis of glaucoma in Japanese patients. STUDY DESIGN:Cross-sectional study. METHODS:Thirty-one eyes of 19 healthy controls and 106 eyes of 70 glaucoma patients underwent standard automated perim...

journal_title：Japanese journal of ophthalmology

authors： Sakamoto M,Mori S,Ueda K,Akashi A,Inoue Y,Kurimoto T,Kanamori A,Yamada Y,Nakamura M

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To assess serial dynamic enhanced computed tomography (serial DE-CT) as a diagnostic tool for carotid-cavernous sinus fistula (CCF). METHODS:Serial DE-CT was performed in seven patients (ages 31-74) with CCF. Contrast material was injected intravenously at a dose of 60 mL with an injection speed of 4 mL per se...

journal_title：Japanese journal of ophthalmology

authors： Ohtsuka K,Hashimoto M

更新日期：1999-11-01 00:00:00

abstract：PURPOSE:To compare the cytotoxicity of povidone-iodine solution (PVP-I) with that of polyvinyl alcohol-iodine solution (PAI) for ophthalmic use. METHODS:Cells of the human corneal epithelial cell line HCE-T were exposed to various dilutions of PVP-I or PAI, and the cytotoxicity of these two antiseptics was evaluated. ...

journal_title：Japanese journal of ophthalmology

authors： Shibata Y,Tanaka Y,Tomita T,Taogoshi T,Kimura Y,Chikama T,Kihira K

更新日期：2014-11-01 00:00:00

abstract：:Glycine is an important inhibitory neurotransmitter in the vertebrate retina. Although many reports of glycine localization by the immunocytochemical method have been published, none has distinguished the neurotransmitter function of glycine from metabolic change. If glycine is the neurotransmitter, it seems that it m...

journal_title：Japanese journal of ophthalmology

authors： Nishikawa S,Ishiguro S,Tamai M

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:To prospectively compare the scotopic pupil size between emmetropes and myopes using a Colvard pupillometer. METHODS:The pupil diameters of 55 normal subjects and 55 healthy myopic subjects were measured with the Colvard pupillometer in a low-light situation that simulated the level of light encountered while ...

journal_title：Japanese journal of ophthalmology

authors： Chaidaroon W,Juwattanasomran W

更新日期：2002-11-01 00:00:00

abstract：:Purpose: A young patient of ophthalmoplegic migraine with recurrent oculomotor nerve palsy is reported.Case: A 4-year-old girl came to our hospital complaining of recurrent left ptosis and double vision which completely resolved within a few days. She had a history of drowsiness after vomiting every two months. Left o...

journal_title：Japanese journal of ophthalmology

authors： Ishikawa H,Yoshihara M,Mizuki K,Kashima Y

更新日期：2000-09-01 00:00:00

abstract：PURPOSE:We evaluated central retinal thickness (CRT) in diabetic macular edema (DME) using two different spectral-domain (SD) optical coherence tomography (OCT) instruments: the Cirrus and Spectralis OCTs. METHODS:CRT was measured in 63 eyes of 32 patients with DME using both instruments on the same day. RESULTS:CRT ...

journal_title：Japanese journal of ophthalmology

authors： Suzuma K,Yamada Y,Liu M,Tsuiki E,Fujikawa A,Kitaoka T

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:To investigate the differences in thickness and depth of the lamina cribrosa (LC) between ocular hypertension (OH) patients and normal control subjects, using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (SD-OCT). METHODS:EDI-OCT data were obtained from the subjects in a cross-sect...

journal_title：Japanese journal of ophthalmology

authors： Han JC,Choi DY,Kwun YK,Suh W,Kee C

更新日期：2016-01-01 00:00:00

abstract：:It is unknown whether aqueous flare is increased in eyes with prominent fundus lesions other than choroidal malignant melanoma. Therefore, we studied the aqueous flare in eyes with age-related macular degeneration (ARMD) using the laser flare-cell meter. Forty-three eyes of 27 patients with ARMD (age 67.0 +/- 14.0 yea...

journal_title：Japanese journal of ophthalmology

authors： Kubota T,Küchle M,Nguyen NX

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:To examine the effects of topical steroid instillation on central corneal thickness in eyes with bullous keratopathy (BK). STUDY DESIGN:Retrospective case series METHODS: Consecutive patients with BK who did not wish to receive corneal transplantation and were treated with 0.1% betamethasone eyedrops were incl...

journal_title：Japanese journal of ophthalmology

authors： Ono T,Iwasaki T,Yukawa C,Mori Y,Nejima R,Tokunaga T,Amano S,Miyata K

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:We investigated the efficacy of the tear sampling method using a filter paper to evaluate eosinophil cationic protein (ECP) levels in patients with allergic disorders. METHODS:Subjects were an allergic group comprising patients with allergic conjunctivitis, vernal keratoconjunctivitis, or atopic keratoconjunct...

journal_title：Japanese journal of ophthalmology

authors： Shoji J,Kitazawa M,Inada N,Sawa M,Ono T,Kawamura M,Kato H

更新日期：2003-01-01 00:00:00

abstract：:Histochemical studies were carried out in the mouse on the changes and distribution patterns of glycosaminoglycan molecular species during the separation of the lens vesicle. To obtain embryos, pregnant mice of the Jcl:ICR strain were sacrificed on day 10.5 or 11 of pregnancy. Serial frontal sections were strained wit...

journal_title：Japanese journal of ophthalmology

authors： Mizuno S,Ikeda K,Hirabayashi Y

更新日期：1995-01-01 00:00:00

abstract：:Fibronectin (FN) has been detected at the site of corneal wounds. To investigate whether FN is supplied by the cornea itself or by extracorneal sources, we cultured small blocks of rabbit cornea in vitro with and without autologous serum (5%). The sliding rate of epithelial cells was determined and localization of FN ...

journal_title：Japanese journal of ophthalmology

authors： Nishida T,Nakagawa S,Ohashi Y,Awata T,Manabe R

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:To assess intravitreal bevacizumab (IVB) for choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) in Japanese patients. METHODS:Forty-seven patients treated with IVB for newly diagnosed subfoveal or juxtafoveal CNV (predominantly classic CNV, 15 eyes; minimally classic CNV, 11...

journal_title：Japanese journal of ophthalmology

authors： Suzuki M,Gomi F,Sawa M,Tsujikawa M,Sakaguchi H

更新日期：2010-03-01 00:00:00