Abstract：
PURPOSE:To investigate the differences in thickness and depth of the lamina cribrosa (LC) between ocular hypertension (OH) patients and normal control subjects, using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (SD-OCT). METHODS:EDI-OCT data were obtained from the subjects in a cross-sectional analysis of data from a retrospective study. After IOP correction according to central corneal thickness (CCT), we divided the OH patients into two groups based on the corrected IOP (cIOP)--OH with lower IOP (OH-L; cIOP < 23 mmHg) and OH with higher IOP (OH-H; cIOP ≥ 23 mmHg). Comparisons of LC thickness and depth among three groups were performed. RESULTS:Seventy-four OH patients and 45 normal control subjects were included in the analysis. Among the 74 OH patients, 41 were included in the OH-L group and 33 were included in the OH-H group. LC thickness was thicker in the OH-H group compared to normal controls both in superior (P = 0.02) and inferior (P = 0.01) portions. However, no difference was found in LC depth among the three groups in any portion (P = 0.36; P = 0.44; P = 0.31, respectively). CONCLUSION:OH patients may have a thicker LC than normal control subjects, especially in OH with definite high IOP.
journal_name
Jpn J Ophthalmoljournal_title
Japanese journal of ophthalmologyauthors
Han JC,Choi DY,Kwun YK,Suh W,Kee Cdoi
10.1007/s10384-015-0407-zsubject
Has Abstractpub_date
2016-01-01 00:00:00pages
14-9issue
1eissn
0021-5155issn
1613-2246pii
10.1007/s10384-015-0407-zjournal_volume
60pub_type
杂志文章abstract：PURPOSE:To determine the morphological characteristics of the cornea in eyes with posterior corneal vesicles (PCV) determined by in vivo confocal microscopy (IVCM). In addition, to compare the morphological characteristics of the corneas of eyes with PCV to those of eyes with posterior polymorphous corneal dystrophy (P...
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pub_type： 杂志文章
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