Anatomical and physiological studies on the aqueous sinus artery of the pigeon eye.

Abstract:

PURPOSE:To test the hypothesis that ischemia of the Schlemm's canal endothelium is involved in the control of intraocular pressure (IOP). METHODS:Experiments were conducted on pigeons. The course of the aqueous sinus and the aqueous sinus artery was determined by examining serial sections and the distribution of polymerized resin in the limbal region of the pigeon eye. Ischemia was produced by blocking two major arteries to the aqueous sinus artery and then determining the effect on the IOP. RESULTS:The anatomy and course of the pigeon aqueous sinus and aqueous sinus artery indicated that they are homologous to the human Schlemm's canal and Schlemm's canal artery, respectively. When the arterial inflow to the aqueous sinus artery was blocked by laser treatment, injected resin was absent in the artery but a small amount invaded the aqueous sinus. Blockage of the two major arteries to the aqueous sinus artery did not alter the IOP. CONCLUSIONS:The similarity of the pigeon aqueous sinus and aqueous sinus artery to the human Schlemm's canal and Schlemm's canal artery indicates that the pigeon eye can be used to study the relationship between ischemia of the endothelial meshwork cells and IOP. The lack of a change in IOP in pigeons after ischemia induction was probably the result of anastomotic arterial blood inflow to the aqueous sinus directly, and thus ischemia was not produced by blocking the two major arteries to the aqueous sinus artery.

journal_name

Jpn J Ophthalmol

authors

Nakabayashi M

doi

10.1016/s0021-5155(99)00017-9

keywords:

subject

Has Abstract

pub_date

1999-07-01 00:00:00

pages

262-71

issue

4

eissn

0021-5155

issn

1613-2246

pii

S0021-5155(99)00017-9

journal_volume

43

pub_type

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