Lens epithelial cells in postoperative aqueous humor.

abstract：PURPOSE:To perform a retrospective study to evaluate the long-term outcome of systemic cyclosporine treatment as an adjunct to topical corticosteroid treatment after penetrating keratoplasty (PKP). METHODS:Twenty-six high-risk patients (27 eyes) who received systemic cyclosporine following PKP for an average of 5.4 mo...

journal_title：Japanese journal of ophthalmology

authors： Inoue K,Kimura C,Amano S,Sato T,Fujita N,Kagaya F,Kaji Y,Tsuru T,Araie M

更新日期：2001-07-01 00:00:00

abstract：:We assessed the function of Endothelin-1 (ET-1) in the development of anterior chamber inflammation in pigmented rabbit eyes. After the injection of ET-1 solution (10(-13), 10(-11), 10(-9), or 10(-7) M, diluted with 300 microL of artificial aqueous humor) into the anterior chamber, the aqueous protein concentration (A...

journal_title：Japanese journal of ophthalmology

authors： Shoji N,Oshika T,Masuda K

更新日期：1997-05-01 00:00:00

abstract：PURPOSE:To compare the outcome of early treatment at the initial stage 3 moderate phase of retinopathy of prematurity (ROP) with that at prethreshold ROP. METHODS:The outcome of treatment of 117 very-low-birth-weight infants was reviewed. Sixty-eight infants underwent their first treatment at prethreshold ROP (group A...

journal_title：Japanese journal of ophthalmology

authors： Hatsukawa Y,Ueki N,Yamagishi T,Kitajima H

更新日期：2005-09-01 00:00:00

abstract：PURPOSE:To examine the effectiveness, safety, and stability of laser subepithelial keratomileusis (LASEK), a modified photorefractive keratectomy for low to moderate myopia. METHODS:This study evaluated the results of LASEK in 48 myopic patients (84 eyes) with a consecutive 6-month follow-up period. Preoperative myopi...

journal_title：Japanese journal of ophthalmology

authors： Lee JB,Choe CM,Seong GJ,Gong HY,Kim EK

更新日期：2002-05-01 00:00:00

abstract：PURPOSE:To evaluate the clinical significance of 5-S-cysteinyldopa (5-S-CD), a major intermediate in melanin synthesis, as a potential diagnostic tumor marker for uveal malignant melanoma. METHODS:The levels of 5-S-CD in the serum were measured by high-performance liquid chromatography in 16 patients with primary uvea...

journal_title：Japanese journal of ophthalmology

authors： Goto H,Usui M,Wakamatsu K,Ito S

更新日期：2001-09-01 00:00:00

abstract：:Movement of fluorescein and fluorescein glucuronide, a fluorescent metabolite of fluorescein, across the isolated iris-ciliary body of the albino rabbit was determined under short-circuit conditions using a modified Ussing's chamber. The permeabilities of this tissue to these dyes were calculated. The outward permeabi...

journal_title：Japanese journal of ophthalmology

authors： Eguchi S,Araie M,Takase M

更新日期：1987-01-01 00:00:00

abstract：:Long-term incubation of the lens of rainbow trout, a cold water fish, can be carried out at 0 degrees C, without altering its transparency. This is not possible in mammalian lenses. Rainbow trout lenses maintained their transparency with normal cation levels for 2.5 months in H10 medium, which is a simple balanced sal...

journal_title：Japanese journal of ophthalmology

authors： Hikida M,Iwata S

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Vogt-Koyanagi-Harada (VKH) disease patients with the complication of subretinal pigmented proliferative tissue tend to have a poor visual prognosis. CASE:We herein report a case of VKH with good visual acuity despite a prominent subretinal fold. OBSERVATIONS:A 24-year-old woman, who experienced several rec...

journal_title：Japanese journal of ophthalmology

authors： Noda Y,Sonoda KH,Nakamura T,Kawano YI,Ishibashi T,Inomata H

更新日期：2003-11-01 00:00:00

abstract：PURPOSE:To evaluate the effects of topical latanoprost and timolol in combined therapy on retinal blood flow and tissue circulation in the optic nerve head (ONH) of the cynomolgus monkey. METHODS:Latanoprost (30 microL, 0.005%) was instilled once daily and timolol (30 microL, 0.5%) twice daily for 6 days into 1 eye, a...

journal_title：Japanese journal of ophthalmology

authors： Ishii K,Araie M

更新日期：2000-05-01 00:00:00

abstract：:It has been reported that keratocytes endocytose foreign particles both in vitro and in vivo, suggesting the active participation of keratocytes in corneal wound healing and host defense mechanism. To understand the cellular response and the fate of engulfed foreign particles, we investigated the changes in the lysoso...

journal_title：Japanese journal of ophthalmology

authors： Mishima H,Ueda A,Nishida T,Otori T

更新日期：1992-01-01 00:00:00

abstract：:Diabetic retinopathy is a frequent cause of visual impairment in working-age adults (≥ 30 years) and in Japan is most commonly observed in those aged 50-69 years. Diabetic macular edema (DME) is one of the main causes of vision disturbance in diabetic retinopathy, which is a clinically significant microvascular compli...

journal_title：Japanese journal of ophthalmology

authors： Terasaki H,Ogura Y,Kitano S,Sakamoto T,Murata T,Hirakata A,Ishibashi T

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:A new method for quantification of metamorphopsia was applied to study distorted vision in patients with epiretinal membrane. METHOD:Sixty-three patients with unilateral epiretinal membrane in the macula were examined. A modified Amsler chart (a grid of black lines on a white background measuring 12 x 12 cm wi...

journal_title：Japanese journal of ophthalmology

authors： Shinoda K,Ishida S,Kawashima S,Matsuzaki T,Yamada K,Katsura H

更新日期：2000-07-01 00:00:00

abstract：PURPOSE:To investigate whether retinal glial cells (RGCs), which are believed to play an important role in the development and maintenance of microvessels, stimulate the proliferation of retinal bovine microvascular pericytes, an essential component of the vessels. METHODS:Conditioned medium (CM) was collected from a ...

journal_title：Japanese journal of ophthalmology

authors： Ikuno Y,Hibino S,Bando H,Kawasaki Y,Nakamura T,Tano Y

更新日期：2002-07-01 00:00:00

abstract：PURPOSE:We retrospectively investigated the efficacy of corneal crosslinking (CXL) on progressive keratoconus in a Japanese population and compared the outcomes of conventional and accelerated CXL. STUDY DESIGN:A retrospective cohort study METHODS: A total of 108 consecutive eyes in 95 patients (75 men; 21.9 ± 6.2 yea...

journal_title：Japanese journal of ophthalmology

authors： Kato N,Konomi K,Shinzawa M,Kasai K,Ide T,Toda I,Sakai C,Negishi K,Tsubota K,Shimazaki J

更新日期：2018-09-01 00:00:00

abstract：:Glycine is an important inhibitory neurotransmitter in the vertebrate retina. Although many reports of glycine localization by the immunocytochemical method have been published, none has distinguished the neurotransmitter function of glycine from metabolic change. If glycine is the neurotransmitter, it seems that it m...

journal_title：Japanese journal of ophthalmology

authors： Nishikawa S,Ishiguro S,Tamai M

更新日期：1996-01-01 00:00:00

abstract：:Single fiber electromyography (SFEMG) was carried out in the extraocular muscles (EOMs) of 40 adult cats, and the recordings were analyzed. The small fluctuations of the interpotential interval (IPI), so-called "jitter phenomenon", were represented quantitatively as a mean consecutive difference (MCD). The MCD and the...

journal_title：Japanese journal of ophthalmology

authors： Hattori M,Mimura O,Haruta R,Uyama J,Shimo-Oku M

更新日期：1986-01-01 00:00:00

abstract：:We evaluated the clinical statistics of a total of 186 patients (101 men and 85 women) with Vogt-Koyanagi-Harada's disease seen in the Uveitis Survey Clinic of the Hokkaido University Hospital during the 18-year period from 1966 to 1983. The annual number of new cases showed some change. More new patients were seen in...

journal_title：Japanese journal of ophthalmology

authors： Ohno S,Minakawa R,Matsuda H

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To determine whether photoreceptor degeneration in transgenic (Tg) rabbits carrying the Pro347Leu rhodopsin mutation alters the neural activity of the middle and inner retinal neurons. METHODS:Multifocal electroretinograms (mfERGs) were recorded from eight 12-week-old Tg rabbits both before and after intravitr...

journal_title：Japanese journal of ophthalmology

authors： Yokoyama D,Machida S,Kondo M,Terasaki H,Nishimura T,Kurosaka D

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To determine whether P7C3-A20, a proneurogenic neuroprotective agent, can protect the retinal ganglion cells (RGCs) of rats from optic nerve crushing. METHODS:The left optic nerve of 67 rats was crushed, and 5.0 mg/kg/day of P7C3-A20 (crush-P7C3) or its vehicle (crush-placebo) was injected intraperitoneally fo...

journal_title：Japanese journal of ophthalmology

authors： Oku H,Morishita S,Horie T,Nishikawa Y,Kida T,Mimura M,Kojima S,Ikeda T

更新日期：2017-03-01 00:00:00

abstract：:The morphological appearance and the quantitative analysis of the structure of the macular microvasculature were investigated in 33 normal subjects by fluorescein angiography and stereoscopic mapping techniques. The foveal capillary network was formed by the anastomosis of 4 to 6 groups of terminal arteriolar and veno...

journal_title：Japanese journal of ophthalmology

authors： Wu LZ,Huang ZS,Wu DZ,Chan E

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To evaluate the cycloplegic effect of mixed eye drops containing 0.5% tropicamide and 0.5% phenylephrine in myopic children, and to determine whether their efficacy was associated with their clinical characteristics. METHODS:Eighty-one myopic children (age, mean +/- SD, 11.0 +/- 1.5 years; mean spherical equiv...

journal_title：Japanese journal of ophthalmology

authors： Hamasaki I,Hasebe S,Kimura S,Miyata M,Ohtsuki H

更新日期：2007-03-01 00:00:00

abstract：:Using polymerase chain reaction, we detected the varicella-zoster virus genome in the vitreous humor of two patients with clinically diagnosed acute retinal necrosis. One of the two cases was thought to be caused by infection with a varicella-zoster virus lacking a PstI cleavage site. We could not find any clinical di...

journal_title：Japanese journal of ophthalmology

authors： Mochizuki K,Matsushita H,Hiramatsu Y,Yanagida K

更新日期：1998-05-01 00:00:00

abstract：PURPOSE:To identify any possible determinants in the development of uveitis in leprosy patients. METHODS:Human leukocyte antigen (HLA) class I and II antigen, and HLA class II genotypings were analyzed among Japanese leprosy patients. Ninety-three unrelated Japanese leprosy patients (46 patients with a history of uvei...

journal_title：Japanese journal of ophthalmology

authors： Joko S,Numaga J,Maeda H

更新日期：1999-03-01 00:00:00

abstract：PURPOSE:We evaluated the use of immunological biomarkers in transconjunctival immunotherapy by using cholera toxin B for treating experimental allergic conjunctivitis in a mouse model. METHODS:Balb/c mice were sensitized using intraperitoneal injections of ovalbumin (OVA) and were then divided into two groups. The fir...

journal_title：Japanese journal of ophthalmology

authors： Oikawa A,Shoji J,Inada N,Sawa M

更新日期：2011-09-01 00:00:00

abstract：:Distribution of microglia cells was studied in the normal retina of Wistar rats kept in a specific-pathogen-free condition, using a combined technique of light and electron microscopy with the weak silver carbonate staining method of del Rio-Hortega. Typical microglia cells were found mainly in the inner plexiform lay...

journal_title：Japanese journal of ophthalmology

authors： Kohno T,Inomata H,Taniguchi Y

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:To examine using the folds of the retinal pigment epithelium (RPE) to diagnose Vogt-Koyanagi-Harada (VKH) disease. METHODS:Retrospective clinical review of 57 Japanese patients between July 2005 and April 2009. Optical coherence tomography (OCT), fundus photographs and fluorescein angiography (FA) were studi...

journal_title：Japanese journal of ophthalmology

authors： Kato Y,Yamamoto Y,Tabuchi H,Fukushima A

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:We investigated the efficacy of the tear sampling method using a filter paper to evaluate eosinophil cationic protein (ECP) levels in patients with allergic disorders. METHODS:Subjects were an allergic group comprising patients with allergic conjunctivitis, vernal keratoconjunctivitis, or atopic keratoconjunct...

journal_title：Japanese journal of ophthalmology

authors： Shoji J,Kitazawa M,Inada N,Sawa M,Ono T,Kawamura M,Kato H

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of intravitreal drug injections using a short 34-gauge needle. STUDY DESIGN:Retrospective study. METHODS:This study included patients with age-related macular degeneration, diabetic macular edema, or macular edema associated with retinal vein occlusion. We reviewed the medi...

journal_title：Japanese journal of ophthalmology

authors： Sasajima H,Tsuboi K,Murotani K,Kamei M

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:To investigate the expression of beta-defensin in the ocular surface of a mouse experimental allergic conjunctivitis (EAC) model. METHODS:Mouse beta-defensin (mBD)-1 and -2 mRNA expressed in conjunctival tissue of both the EAC and the control group were analyzed by real-time reverse transcriptase-polymerase ch...

journal_title：Japanese journal of ophthalmology

authors： Ikeda A,Nakanishi Y,Sakimoto T,Shoji J,Sawa M,Nemoto N

更新日期：2006-01-01 00:00:00

abstract：:We evaluated the effectiveness of performing a core vitrectomy to prevent intraoperative posterior chamber pressure evaluation in eyes at high risk for development of this complication, prior to penetrating keratoplasty, extracapsular cataract extraction and posterior chamber lens (IOL) implantation. Results in 10 cas...

journal_title：Japanese journal of ophthalmology

authors： Shimomura Y,Hosotani H,Kiritoshi A,Watanabe H,Tano Y

更新日期：1997-07-01 00:00:00