Expression of beta defensins in ocular surface tissue of experimentally developed allergic conjunctivitis mouse model.

abstract：PURPOSE:To investigate gelatinase [matrix metalloproteinase (MMP)-2 and MMP-9] expression in the tear fluid of patients with recurrent corneal erosion (RCE). METHODS:Eleven patients with RCE, three patients with traumatic corneal erosion, and 10 control individuals were enrolled in this study. Tear samples from RCE ey...

journal_title：Japanese journal of ophthalmology

authors： Sakimoto T,Shoji J,Yamada A,Sawa M

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To investigate the prevalence of superior segmental optic nerve hypoplasia in Korea. METHODS:We reviewed the fundus photographs of 3905 individuals who were 40 years old or older and who participated in the comprehensive medical examination program at the Health Promotion Center of Seoul National University Bu...

journal_title：Japanese journal of ophthalmology

authors： Han SB,Park KH,Kim DM,Kim TW

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:To evaluate the effect of preservative-free (PF) tafluprost on diurnal variation of intraocular pressure (IOP) and ocular perfusion pressure (OPP), measured by use of home IOP and blood-pressure (BP) monitoring devices, for primary open angle glaucoma (POAG) patients. METHODS:Twenty-two eyes from 22 patients w...

journal_title：Japanese journal of ophthalmology

authors： Cho SY,Kim YY,Yoo C,Lee TE

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To determine the psychological state and personality traits of patients with retinitis pigmentosa (RP) or glaucoma so that a closer and better relationship can be developed with the patients. METHODS:The Yatabe-Guilford personality test was administered to 75 RP patients and 42 glaucoma patients. The latter gr...

journal_title：Japanese journal of ophthalmology

authors： Igarashi Y,Sato E,Ito A,Miyauchi O,Ikejiri M,Hanawa T,Tsuyama Y,Mizota A,Fujimoto N,Adachi-Usami E

更新日期：2003-01-01 00:00:00

abstract：:We evaluated the effectiveness of performing a core vitrectomy to prevent intraoperative posterior chamber pressure evaluation in eyes at high risk for development of this complication, prior to penetrating keratoplasty, extracapsular cataract extraction and posterior chamber lens (IOL) implantation. Results in 10 cas...

journal_title：Japanese journal of ophthalmology

authors： Shimomura Y,Hosotani H,Kiritoshi A,Watanabe H,Tano Y

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Interferon alpha-2b (IFN alpha 2b) was recently shown to be effective as an alternative therapy for conjunctival intraepithelial neoplasia (CIN). Herein, we report our successful management of CIN by the use of IFN alpha 2b. CASE:A 73-year-old woman presented with a complaint of irritation due to a tumorous...

journal_title：Japanese journal of ophthalmology

authors： Kobayashi A,Yoshita T,Uchiyama K,Shirao Y,Kitagawa K,Fujisawa A,Tseng SC

更新日期：2002-03-01 00:00:00

abstract：PURPOSE:We investigated the efficacy of the tear sampling method using a filter paper to evaluate eosinophil cationic protein (ECP) levels in patients with allergic disorders. METHODS:Subjects were an allergic group comprising patients with allergic conjunctivitis, vernal keratoconjunctivitis, or atopic keratoconjunct...

journal_title：Japanese journal of ophthalmology

authors： Shoji J,Kitazawa M,Inada N,Sawa M,Ono T,Kawamura M,Kato H

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:To report the reproducibility profile of optic nerve head parameters obtained by computer software-assisted fundus photoplanimetry. METHODS:Fundus photographs obtained during a population-based health survey (Sakurae Study) were planimetrically analyzed using newly developed computer software, CDSketch. The pa...

journal_title：Japanese journal of ophthalmology

authors： Tanito M,Sagara T,Takamatsu M,Kiuchi Y,Nakagawa T,Fujita Y,Ohira A

更新日期：2014-01-01 00:00:00

abstract：:The glycocalyx, present on the surface of the corneal epithelium, contains sialoglycoconjugates. The developmental change in the sialylated residues may be evaluated by examining the expression of the sialyltransferase mRNA. We examined the distribution of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase mRNA in rat cor...

journal_title：Japanese journal of ophthalmology

authors： Uehara F,Ozawa M,Iwakiri N,Ohba N

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:To elucidate clinical and angiographic features of retinal manifestations in cat scratch disease. METHODS:Clinical characteristics as well as fluorescein and indocyanine green (ICG) angiographic features were reviewed in 4 consecutive patients with retinal manifestations caused by serologically confirmed cat s...

journal_title：Japanese journal of ophthalmology

authors： Matsuo T,Yamaoka A,Shiraga F,Takasu I,Okanouchi T,Nagayama M,Baba T,Hayashi M,Sarada K

更新日期：2000-03-01 00:00:00

abstract：PURPOSE:We evaluated ocular symptoms and activity of retinal vasculitis of Behçet disease before and after infliximab therapy, using Behçet disease ocular attack score 24 (BOS24) and fluorescein angiography (FA) score. We also analyzed the efficacy of infliximab for ocular and extraocular symptoms. STUDY DESIGN:Retros...

journal_title：Japanese journal of ophthalmology

authors： Umazume A,Kezuka T,Usui Y,Suzuki J,Goto H

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To elucidate the current clinical practice patterns of branch retinal vein occlusion (BRVO) management by retina specialists in Japan in the era of anti-vascular endothelial growth factor (VEGF) therapy. STUDY DESIGN:A voting survey using an answer pad system. METHODS:On May 28, 2017, forty-one retina special...

journal_title：Japanese journal of ophthalmology

authors： Ogura Y,Kondo M,Kadonosono K,Shimura M,Kamei M,Tsujikawa A

更新日期：2019-09-01 00:00:00

abstract：:Spontaneous retinal degeneration of Celestial goldfish was studied histologically and electrophysiologically. Retinal degeneration was divided into three stages. Until the age of 75 days (Stage 0) the retina showed normal histological development and the electroretinograms (ERGs) exhibited dominant b-waves similar to ...

journal_title：Japanese journal of ophthalmology

authors： Sakaue H,Negi A,Matsumura M,Ohkuma M,Honda Y

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:To investigate the differences in thickness and depth of the lamina cribrosa (LC) between ocular hypertension (OH) patients and normal control subjects, using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (SD-OCT). METHODS:EDI-OCT data were obtained from the subjects in a cross-sect...

journal_title：Japanese journal of ophthalmology

authors： Han JC,Choi DY,Kwun YK,Suh W,Kee C

更新日期：2016-01-01 00:00:00

abstract：:In an attempt to compare surgical peripheral iridectomy and laser iridotomy with regards to the long-term control of the intraocular pressure (IOP), analyses were carried out of the clinical records of 195 eyes of 149 primary angle-closure glaucoma patients who had undergone either peripheral iridectomy or laser irido...

journal_title：Japanese journal of ophthalmology

authors： Go FJ,Akiba Y,Yamamoto T,Kitazawa Y

更新日期：1984-01-01 00:00:00

abstract：:A case of unilateral disc-shaped cataract with coloboma of the lens is reported. The patient, a 17-year-old girl, had best corrected visual acuity of 0.01 (+ 9 D) in the right eye and 1.2 in the left eye. Exotropia of 10 Hirschberg degrees was found in her right eye. The visual disturbance of that eye was thought to b...

journal_title：Japanese journal of ophthalmology

authors： Kihara Y,Shimomura Y,Omoto T,Fukuda M

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to experimentally investigate changes in visible light-induced photo-oxidation and to evaluate the inhibitory effect of various acrylic tinted intraocular lenses (IOLs) on photooxidation. METHODS:Three types of nontinted (VA-60BB, HOYA; SA60AT, Alcon; AU-6, Menicon) and tinted (YA-60B...

journal_title：Japanese journal of ophthalmology

authors： Mukai K,Matsushima H,Sawano M,Nobori H,Obara Y

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:To investigate cytokine mRNA expression during the inflammatory process induced in the contralateral eyes by uniocular inoculation of herpes simplex virus type 1 (HSV-1) via the anterior chamber. METHODS:BALB/c mice were inoculated in the anterior chamber with 5 x 10(4) plaque-forming units of HSV-1 (KOS). mRN...

journal_title：Japanese journal of ophthalmology

authors： Saitoh-Ishibashi K,Ishibashi K,Azumi A,Negi A

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:To evaluate the effect of tetramethylpyrazine on the elevation of aqueous flare and intraocular pressure (IOP) induced by prostaglandin (PG) E(2) and PGE(2) receptor (EP) agonists. METHODS:PGE(2) or EP agonists (11-deoxy PGE(1), EP(2) agonist; 17-phenyl trinor PGE(2), EP(1) and EP(3) agonist; or sulprostone, E...

journal_title：Japanese journal of ophthalmology

authors： Kitagawa K,Hayasaka S,Nagaki Y,Watanabe K

更新日期：2001-05-01 00:00:00

abstract：PURPOSE:To clarify the neuronal mechanism for the square-wave jerks (SWJs). METHODS:A 66-year-old man presented with oscillatory eye movements. He showed horizontal nystagmus in rightward gaze and SWJs during fixation at straight ahead. We recorded his eye movements with search coil methods and quantitatively analyzed...

journal_title：Japanese journal of ophthalmology

authors： Suzuki Y,Kase M,Hashimoto M,Ohtsuka K

更新日期：2003-11-01 00:00:00

abstract：:A 76-year-old Japanese woman had suffered from fatigue, weight loss, and cutaneous hyperpigmentation at the age of 38 years and was diagnosed as having tuberculous Addison's disease. Since then, corticosteroids had been administered effectively as hormonal replacement. At the age of 75 years, the patient presented wit...

journal_title：Japanese journal of ophthalmology

authors： Kakiuchi T,Uehara F,Ohba N

更新日期：1998-09-01 00:00:00

abstract：PURPOSE:To investigate the process of repair in the epithelial cells and the reconstruction in lens fibers of a mouse lens that has developed opacity because of a large-scale perforating injury. METHODS:Lenses of 4-week-old mice were perforated with a needle through the cornea to induce the development of traumatic ca...

journal_title：Japanese journal of ophthalmology

authors： Hirayama S,Wakasugi A,Morita T,Sakai Y,Mukuno K,Uga S,Shimizu K

更新日期：2003-07-01 00:00:00

abstract：:We studied the inhibitory effects of chicken egg white ovomacroglobulin, a broad-spectrum protease inhibitor, and a synthetic protease inhibitory peptide, Bz-GFR-O-mercaptoanilide, on the growth of two strains of Serratia marcescens in a synthetic medium. The growth of the virulent protease-producing strain, S. marces...

journal_title：Japanese journal of ophthalmology

authors： Miyagawa S,Matsumoto K,Kamata R,Okamura R,Maeda H

更新日期：1991-01-01 00:00:00

abstract：:Three cases of medullated nerve fibers of the retina were seen. They had medullated nerve fibers in both the upper and lower quadrants of the temporal retina, whereby the temporal raphe of the retinal nerve fiber layer could be visualized. Some nerve fibers from the upper and lower quadrants crossed each other on the ...

journal_title：Japanese journal of ophthalmology

authors： Sakai T,Sano K,Tsuzuki K,Ueno M,Kawamura Y

更新日期：1987-01-01 00:00:00

abstract：:Purpose: To confirm the intraocular dynamics of 1% deuterium (D) labeled alpha-tocopheral acetate (VEA) solution.Methods: The concentrations of D(3)-VEA and D(3)-alpha-tocopherol (VE) derived from D(3)-VEA in the aqueous humor and lens were measured after instilling 1% D(3)-VEA continuously into the cul-de-sac of rat ...

journal_title：Japanese journal of ophthalmology

authors： Nagata M,Kawazu K,Midori Y,Kojima M,Shirasawa E,Sasaki K

更新日期：2001-01-01 00:00:00

abstract：:A case of bilateral retinoblastoma affecting both of a pair of dizygotic twins was reported. To our knowledge, there has been only one previous report of dizygotic twins, both affected, with this disease. The present twins had no family history of retinoblastoma. They were born prematurely as extremely low birth weigh...

journal_title：Japanese journal of ophthalmology

authors： Amino K,Ichioka I,Ichioka H,Matsubara K,Lin YW,Ohta S

更新日期：1992-01-01 00:00:00

abstract：:The superior colliculus (SC) plays an important role in the transformation of visual and auditory signals into motor commands to generate saccadic eye movements toward the targets. This study investigated the synaptic input patterns from the SC, into vertical eye movement-related superior and inferior rectus motoneuro...

journal_title：Japanese journal of ophthalmology

authors： Sasaki Y,Matsui H,Tamai A

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:To evaluate the capability of optical coherence tomography (OCT), retinal nerve fiber layer (RNFL) thickness, and visual field (VF) measurements in glaucoma progression detection. METHODS:The study examined 62 eyes of 37 glaucoma patients observed over a 3-year period. All eyes underwent at least four serial R...

journal_title：Japanese journal of ophthalmology

authors： Tenkumo K,Hirooka K,Baba T,Nitta E,Sato S,Shiraga F

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:Vogt-Koyanagi-Harada (VKH) disease is known to have varied manifestations in different ethnic groups. In order to analyze the clinical profile of VKH cases in the Indian population, we studied 87 consecutive cases of VKH disease treated in an uveitis clinic in South India between 1985 and 1996. METHODS:Retrosp...

journal_title：Japanese journal of ophthalmology

authors： Mondkar SV,Biswas J,Ganesh SK

更新日期：2000-05-01 00:00:00

abstract：:Full-field electroretinograms (ERGs) provide a basis for establishing the diagnosis of widespread progressive forms of retinitis pigmentosa in early life even at a time when fundus abnormalities visible with the ophthalmoscope are minimal or absent. Patients characteristically show delays in rod or cone b-wave implici...

journal_title：Japanese journal of ophthalmology

authors： Berson EL

更新日期：1987-01-01 00:00:00