Detection of varicella-zoster virus genome in the vitreous humor from two patients with acute retinal necrosis; lacking or having a PstI cleavage site.

Abstract:

:Using polymerase chain reaction, we detected the varicella-zoster virus genome in the vitreous humor of two patients with clinically diagnosed acute retinal necrosis. One of the two cases was thought to be caused by infection with a varicella-zoster virus lacking a PstI cleavage site. We could not find any clinical differences between the two substrains. The presence of a PstI cleavage site on the varicella-zoster virus genome might not be associated with the occurrence of acute retinal necrosis.

journal_name

Jpn J Ophthalmol

authors

Mochizuki K,Matsushita H,Hiramatsu Y,Yanagida K

doi

10.1016/s0021-5155(98)00005-7

subject

Has Abstract

pub_date

1998-05-01 00:00:00

pages

208-12

issue

3

eissn

0021-5155

issn

1613-2246

pii

S0021-5155(98)00005-7

journal_volume

42

pub_type

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