Suppression of experimental autoimmune uveoretinitis by anti-alphabeta TCR monoclonal antibody.

abstract：PURPOSE:To evaluate changes in conjunctival-scleral thickness following strabismus surgery with anterior segment optical coherence tomography (AS-OCT). STUDY DESIGN:Prospective, observational, consecutive case series. METHODS:Distances between the conjunctival epithelium and inner scleral wall were measured with AS-O...

journal_title：Japanese journal of ophthalmology

authors： Suzuki H,Hikoya A,Komori M,Inagaki R,Haseoka T,Arai S,Takagi Y,Hotta Y,Sato M

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:To investigate whether retinal glial cells (RGCs), which are believed to play an important role in the development and maintenance of microvessels, stimulate the proliferation of retinal bovine microvascular pericytes, an essential component of the vessels. METHODS:Conditioned medium (CM) was collected from a ...

journal_title：Japanese journal of ophthalmology

authors： Ikuno Y,Hibino S,Bando H,Kawasaki Y,Nakamura T,Tano Y

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:In this report of two Okinawan patients with Beals syndrome and accompanying ocular complications, the symptoms of Beals syndrome and Marfan syndrome are compared. The etiology of these two syndromes is considered in relation to fibrillin. CASES:Case 1 was a 5-year-old boy who showed blue sclera and bilater...

journal_title：Japanese journal of ophthalmology

authors： Takaesu-Miyagi S,Sakai H,Shiroma T,Hayakawa K,Funakoshi Y,Sawaguchi S

更新日期：2004-09-01 00:00:00

abstract：PURPOSE:To assess whether the outcomes of toric intraocular lens (IOL) implantation in eyes with oblique astigmatism can be improved by direct measurements of posterior corneal astigmatism using anterior segment optical coherence tomography (AS-OCT) instead of by using anterior corneal measurements alone. STUDY DESIGN...

journal_title：Japanese journal of ophthalmology

authors： Nakano S,Iida M,Hasegawa Y,Hiraoka T,Oshika T

更新日期：2021-01-28 00:00:00

abstract：PURPOSE:To identify a mutation in the PRPF31 gene in a family (Family K) with autosomal dominant retinitis pigmentosa (adRP) linked to 19q13.4 (RP11) and to find the frequency of mutations in the PRPF31 gene among Japanese families with adRP. METHODS:Genomic DNA specimens were prepared from five symptomatic and two as...

journal_title：Japanese journal of ophthalmology

authors： Taira K,Nakazawa M,Sato M

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:To analyze the characteristics and clinical manifestations of clinically diagnosed and serologically confirmed ocular toxocariasis in patients. METHODS:Thirty-three eyes of 33 patients diagnosed as having ocular toxocariasis at the Hallym University Medical Center between January 1999 and December 2008 were in...

journal_title：Japanese journal of ophthalmology

authors： Kwon SI,Lee JP,Park SP,Lee EK,Huh S,Park IW

更新日期：2011-03-01 00:00:00

abstract：:A 25-year-old woman is described whose clinical features included infantile hypotonia, obesity after infancy, intellectual impairment, dysmorphic facial features, short stature, small hands and feet, and abnormal dentition, which are typical of the Prader-Willi syndrome. The patient had almond-shaped eyes, spot-like h...

journal_title：Japanese journal of ophthalmology

authors： Wang XC,Norose K,Kiyosawa K,Segawa K

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:We investigated the efficacy of the tear sampling method using a filter paper to evaluate eosinophil cationic protein (ECP) levels in patients with allergic disorders. METHODS:Subjects were an allergic group comprising patients with allergic conjunctivitis, vernal keratoconjunctivitis, or atopic keratoconjunct...

journal_title：Japanese journal of ophthalmology

authors： Shoji J,Kitazawa M,Inada N,Sawa M,Ono T,Kawamura M,Kato H

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of intravitreal drug injections using a short 34-gauge needle. STUDY DESIGN:Retrospective study. METHODS:This study included patients with age-related macular degeneration, diabetic macular edema, or macular edema associated with retinal vein occlusion. We reviewed the medi...

journal_title：Japanese journal of ophthalmology

authors： Sasajima H,Tsuboi K,Murotani K,Kamei M

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:To investigate the process of repair in the epithelial cells and the reconstruction in lens fibers of a mouse lens that has developed opacity because of a large-scale perforating injury. METHODS:Lenses of 4-week-old mice were perforated with a needle through the cornea to induce the development of traumatic ca...

journal_title：Japanese journal of ophthalmology

authors： Hirayama S,Wakasugi A,Morita T,Sakai Y,Mukuno K,Uga S,Shimizu K

更新日期：2003-07-01 00:00:00

abstract：PURPOSE:To verify the possibility that preoperative topical antibiotics are not essential as long as iodine disinfection is performed during surgery. STUDY DESIGN:Crossover equivalence trial. PATIENTS AND METHODS:In 204 eyes of 102 patients who underwent routine bilateral cataract surgery, 1 eye was treated with intr...

journal_title：Japanese journal of ophthalmology

authors： Matsuura K,Miyazaki D,Sasaki SI,Inoue Y,Sasaki Y,Shimizu Y

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:To evaluate axial length (AL) measurements and refractive outcomes in vitrectomy combined with cataract operation for rhegmatogenous retinal detachment (RRD) with wholly detached macula. STUDY DESIGN:Retrospective, consecutive, comparative, clinical study. METHODS:We reviewed the data of patients treated by v...

journal_title：Japanese journal of ophthalmology

authors： Pak KY,Park KH,Park SW,Byon IS,Lee JE

更新日期：2019-07-01 00:00:00

abstract：:For the past 30 years, I have worked as a physician-scientist in both the clinic and laboratory setting at a number of university medical schools. Encountering patients in the clinic for whom treatment was not available led me to the laboratory in an attempt to develop the appropriate treatment for future patients. Th...

journal_title：Japanese journal of ophthalmology

authors： Nishida T

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:To determine whether the single-flash electroretinogram (ERG) can predict the postoperative outcome in diabetic cases where massive vitreous hemorrhage precludes fundus observation. METHODS:Eighty-five diabetic patients (105 eyes) who underwent vitrectomy due to dense vitreous hemorrhage were studied retrospec...

journal_title：Japanese journal of ophthalmology

authors： Hiraiwa T,Horio N,Terasaki H,Suzuki T,Yamamoto E,Horiguchi M,Miyake Y

更新日期：2003-05-01 00:00:00

abstract：:A case of bilateral retinoblastoma affecting both of a pair of dizygotic twins was reported. To our knowledge, there has been only one previous report of dizygotic twins, both affected, with this disease. The present twins had no family history of retinoblastoma. They were born prematurely as extremely low birth weigh...

journal_title：Japanese journal of ophthalmology

authors： Amino K,Ichioka I,Ichioka H,Matsubara K,Lin YW,Ohta S

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:We previously reported that human conjunctival epithelial cells expressed functioning interleukin-4 receptor α (IL-4Rα). In this study, we investigated whether human corneal epithelial cells also express functioning IL-4Rα. METHODS:The presence of IL-4Rα mRNA and protein in human corneal epithelium was examine...

journal_title：Japanese journal of ophthalmology

authors： Ueta M,Sotozono C,Kinoshita S

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:To investigate effects of alertness on three-dimensional (3D) eye movements. METHODS:During drowsy and alert periods, 3D eye movements were recorded with dual search coils in three normal rhesus monkeys, and in two of these monkeys after placement of bilateral kainic acid lesions of the rostral interstitial nu...

journal_title：Japanese journal of ophthalmology

authors： Suzuki Y,Straumann D,Henn V

更新日期：2000-09-01 00:00:00

abstract：:The clinical and etiological findings in 727 patients with viral conjunctivitis treated from January 1982 through December 1984 at Aoki Eye Clinic in Sapporo, Japan, were presented. The age of the patients ranged from 11 days to 88 years, and the monthly incidences of the disease from 18 to 131 cases, with a clusterin...

journal_title：Japanese journal of ophthalmology

authors： Aoki K,Kawana R,Matsumoto I,Wadell G,de Jong JC

更新日期：1986-01-01 00:00:00

abstract：:Conventional vitreoretinal surgery for proliferative vitreoretinopathy is unsatisfactory despite numerous innovations over the past 20 years. Silicone oil injections in this series resulted in 70% reattachment of these end-stage cases, but within twelve months over 90% had no useful visual result. The development of a...

journal_title：Japanese journal of ophthalmology

authors： Constable I

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:To examine the effect of 1% topical dorzolamide on tissue circulation in the optic nerve head (ONH) of Dutch rabbits. METHODS:A laser speckle tissue circulation analyzer was used. One eye of each rabbit received 1% topical dorzolamide twice daily for 20 days, and the fellow eye received the vehicle in a masked...

journal_title：Japanese journal of ophthalmology

authors： Tamaki Y,Araie M,Muta K

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Full-thickness macular holes usually develop in the elderly population. To the best of our knowledge, there has been no written report of a nontraumatic macular hole in a pediatric patient. CASE:A 10-year-old girl noticed decreased central vision in her left eye without any history of trauma. OBSERVATIONS:...

journal_title：Japanese journal of ophthalmology

authors： Nakano T,Uemura A,Kanda S,Sakamoto T

更新日期：2005-11-01 00:00:00

abstract：:Cell population and proportion of each component cell type in preretinal membranes formed after retinal detachment were studied by light microscopy (LM) and transmission electron microscopy (TEM). The preretinal membranes were surgically obtained from 20 proliferative vitreoretinopathy (PVR) and 7 macular pucker patie...

journal_title：Japanese journal of ophthalmology

authors： Yamashita H,Hori S,Masuda K

更新日期：1986-01-01 00:00:00

abstract：:Purpose: To evaluate the usefulness of a new fixation monitoring system called gaze tracking in the perimetry of glaucomatous eyes. Subjects and Method: We studied the visual field of 106 eyes in 106 persons, comprising 74 eyes with open-angle glaucoma and 32 eyes with ocular hypertension. Perimetry was performed usin...

journal_title：Japanese journal of ophthalmology

authors： Kunimatsu S,Suzuki Y,Shirato S,Araie M

更新日期：2000-03-01 00:00:00

abstract：:We explored the involvement of CD44 isoforms in lymphoproliferative disorder (LPD) of the lacrimal gland of a Sjögren's syndrome patient with unilateral LPD. The CD44 variant with the v6 exon was selectively detected from infiltrating lymphocytes in the gland with LPD, but not from infiltrating lymphocytes in the norm...

journal_title：Japanese journal of ophthalmology

authors： Hiraoka M,Saito I,Tsubota K,Sugai S,Miyasaka N

更新日期：1997-09-01 00:00:00

abstract：:We have adapted intrinsic signal optical imaging of neural activity to the noninvasive functional imaging of the retina. Results to date demonstrate the feasibility and potential of this new method of functional assessment of the retina. In response to visual stimuli, we have imaged reflectance changes in the retina t...

journal_title：Japanese journal of ophthalmology

authors： Ts'o D,Schallek J,Kwon Y,Kardon R,Abramoff M,Soliz P

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:To assess the changes in the size of muscle fibers and the composition of myosin heavy chain (MyHC) isoforms in the global layer (GL) and the orbital layer (OL) of rabbit rectus extraocular muscle (EOM) after recession. METHODS:The right superior rectus muscles of two rabbits were harvested at 3 days or 1, 2, ...

journal_title：Japanese journal of ophthalmology

authors： Park SC,Kim YT,Kim SA,Oh SY

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:To evaluate the changes in aqueous flare in psoriasis patients and to identify the factors that influence the level of aqueous flare. METHODS:We examined the 68 eyes of 34 psoriasis patients and the 68 eyes of 34 healthy subjects with a laser flare-cell meter. Complete dermatologic and ophthalmic examinations ...

journal_title：Japanese journal of ophthalmology

authors： Okamoto F,Umebayasi Y,Ohtsuka F,Hommura S

更新日期：2001-03-01 00:00:00

abstract：PURPOSE:To determine the pharmacological response when dysiherbaine acts on cultured Müller cells, considering the glutamate receptor functions. Dysiherbaine is a new excitotoxic amino acid, which was recently isolated from the liquid extract of a certain sponge. METHODS:Retinas of adult rabbits were used to culture t...

journal_title：Japanese journal of ophthalmology

authors： Minei R

更新日期：2002-03-01 00:00:00

abstract：PURPOSE:To investigate the efficacy of intravitreal bevacizumab for the treatment of idiopathic macular telangiectasia (IMT). METHODS:Ten eyes of eight consecutive patients with IMT were studied. Four eyes had type 1, and six had type 2 IMT according to Yannuzzi's classification. All patients were treated with intravi...

journal_title：Japanese journal of ophthalmology

authors： Matsumoto Y,Yuzawa M

更新日期：2010-07-01 00:00:00

abstract：:Localization of carbonic anhydrase (CA) was investigated in the rat eye by light and electron microscopy, and the inhibitory effects on CA distribution in the rat eye were compared between dorzolamide and acetazolamide. The cobalt sulfide histochemical method was used to study the CA localization. Acidic osmification ...

journal_title：Japanese journal of ophthalmology

authors： Terashima H,Suzuki K,Kato K,Sugai N

更新日期：1996-01-01 00:00:00