Abstract:
:We explored the involvement of CD44 isoforms in lymphoproliferative disorder (LPD) of the lacrimal gland of a Sjögren's syndrome patient with unilateral LPD. The CD44 variant with the v6 exon was selectively detected from infiltrating lymphocytes in the gland with LPD, but not from infiltrating lymphocytes in the normal lacrimal gland, suggesting that the CD44 v6 variant exon may be closely associated with the development of LPD in Sjögren's syndrome.
journal_name
Jpn J Ophthalmoljournal_title
Japanese journal of ophthalmologyauthors
Hiraoka M,Saito I,Tsubota K,Sugai S,Miyasaka Ndoi
10.1016/s0021-5155(97)00072-5subject
Has Abstractpub_date
1997-09-01 00:00:00pages
312-8issue
5eissn
0021-5155issn
1613-2246pii
S0021515597000725journal_volume
41pub_type
杂志文章abstract::Cell population and proportion of each component cell type in preretinal membranes formed after retinal detachment were studied by light microscopy (LM) and transmission electron microscopy (TEM). The preretinal membranes were surgically obtained from 20 proliferative vitreoretinopathy (PVR) and 7 macular pucker patie...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:PURPOSE:To report the reproducibility profile of optic nerve head parameters obtained by computer software-assisted fundus photoplanimetry. METHODS:Fundus photographs obtained during a population-based health survey (Sakurae Study) were planimetrically analyzed using newly developed computer software, CDSketch. The pa...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-013-0280-6
更新日期:2014-01-01 00:00:00
abstract::A 76-year-old Japanese woman had suffered from fatigue, weight loss, and cutaneous hyperpigmentation at the age of 38 years and was diagnosed as having tuberculous Addison's disease. Since then, corticosteroids had been administered effectively as hormonal replacement. At the age of 75 years, the patient presented wit...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0021-5155(98)00024-0
更新日期:1998-09-01 00:00:00
abstract:PURPOSE:To perform a retrospective study to evaluate the long-term outcome of systemic cyclosporine treatment as an adjunct to topical corticosteroid treatment after penetrating keratoplasty (PKP). METHODS:Twenty-six high-risk patients (27 eyes) who received systemic cyclosporine following PKP for an average of 5.4 mo...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0021-5155(01)00339-2
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:Although air bags have been shown to reduce the number of fatalities and serious injuries caused by motor vehicle accidents, there have been many reports of air bag-related ocular injuries. We recently treated air bag-related corneal laceration in a patient wearing eyeglasses at the time of a motor accident....
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0021-5155(99)00007-6
更新日期:1999-05-01 00:00:00
abstract::We assessed the function of Endothelin-1 (ET-1) in the development of anterior chamber inflammation in pigmented rabbit eyes. After the injection of ET-1 solution (10(-13), 10(-11), 10(-9), or 10(-7) M, diluted with 300 microL of artificial aqueous humor) into the anterior chamber, the aqueous protein concentration (A...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0021-5155(97)00032-4
更新日期:1997-05-01 00:00:00
abstract:PURPOSE:To investigate the process of repair in the epithelial cells and the reconstruction in lens fibers of a mouse lens that has developed opacity because of a large-scale perforating injury. METHODS:Lenses of 4-week-old mice were perforated with a needle through the cornea to induce the development of traumatic ca...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0021-5155(03)00075-3
更新日期:2003-07-01 00:00:00
abstract::Prostaglandin D2 (PGD2) and 64E, a derivative of PGs, were tested for their capacity to suppress the growth of retinoblastoma in the nude mouse. Ten million cells of an established cell line of human retinoblastoma, Y-79 cells, were transferred subcutaneously into the nude mouse, and after the transferred cells became...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract:PURPOSE:To investigate the utility values associated with visual loss due to age-related macular degeneration (AMD) in Japanese patients. METHODS:Utility values in 48 Japanese patients with bilateral exudative AMD were measured using the time trade-off and standard gamble methods. RESULTS:The time trade-off method ut...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-010-0893-y
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:To evaluate dry eye symptoms, tear film function and ocular surface changes in patients with psoriasis. METHODS:The Dry Eye Questionnaire and ophthalmic examination including the Schirmer test, tear break-up time, corneal fluorescein test, meibomian gland obstruction and conjunctival impression cytology were a...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-012-0226-4
更新日期:2013-07-01 00:00:00
abstract::S-antigen (S-Ag), a well characterized 45-kDa protein in the photoreceptor cells, induces predominantly T-cell-mediated autoimmune uveitis when injected into experimental animals. Recently, we have shown that native histone H3 protein derived from yeast (Saccharomyces cerevisiae), or a synthetic peptide that is homolo...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:: ...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10384-018-0627-0
更新日期:2018-11-01 00:00:00
abstract::Conventional vitreoretinal surgery for proliferative vitreoretinopathy is unsatisfactory despite numerous innovations over the past 20 years. Silicone oil injections in this series resulted in 70% reattachment of these end-stage cases, but within twelve months over 90% had no useful visual result. The development of a...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Distribution of microglia cells was studied in the normal retina of Wistar rats kept in a specific-pathogen-free condition, using a combined technique of light and electron microscopy with the weak silver carbonate staining method of del Rio-Hortega. Typical microglia cells were found mainly in the inner plexiform lay...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::Long-term incubation of the lens of rainbow trout, a cold water fish, can be carried out at 0 degrees C, without altering its transparency. This is not possible in mammalian lenses. Rainbow trout lenses maintained their transparency with normal cation levels for 2.5 months in H10 medium, which is a simple balanced sal...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:PURPOSE:To compare endothelial damage of the donor cornea in relation to the method of inserting the donor cornea into the recipient anterior chamber during Descemet-stripping automated endothelial keratoplasty (DSAEK). METHODS:Fifteen enucleated pig eyes were used. The donor corneoscleral buttons were mounted in an a...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-009-0713-4
更新日期:2009-09-01 00:00:00
abstract::For the past 30 years, I have worked as a physician-scientist in both the clinic and laboratory setting at a number of university medical schools. Encountering patients in the clinic for whom treatment was not available led me to the laboratory in an attempt to develop the appropriate treatment for future patients. Th...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10384-012-0165-0
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:To shorten the duration of prone positioning after macular hole surgery from 1 week to 1 day, and to evaluate preoperative factors and the initial hole closure rate. METHODS:The subjects were 33 patients (34 eyes) who underwent macular hole surgery between April 1998 and August 1999, and maintained the prone p...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0021-5155(01)00468-3
更新日期:2002-01-01 00:00:00
abstract::Purpose: We have developed a new method for quantification of metamorphopsia and applied it to study distorted vision resulting from epiretinal membrane (ERM).Patients and Methods: We prepared a modified Amsler chart, which was a square grid formed by black lines on a white background with 12 cm on a side and divided ...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0021-5155(00)00157-x
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:We present 6 cases of bacterial infection that developed after porous orbital implant surgery. CASES:Five patients with hydroxyapatite implants showed lid swelling, discharge, and suppurative granuloma 14 days to 3 years after surgery. The hydroxyapatite implants were removed 14 days to 41 months postoperat...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0021-5155(03)00137-0
更新日期:2003-09-01 00:00:00
abstract:PURPOSE:The involvement of cytokines and chemokines in vitreous fluid is important in the development and progression of diabetic retinopathy (DR) and central retinal vein occlusion (CRVO). In this study, the concentrations of cytokines and chemokines in the vitreous fluid of eyes with DR and CRVO were measured and com...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-011-0004-8
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:To determine the relationship between apoptotic photoreceptor cell death and the duration of light exposure. METHODS:Ten-week-old male albino rats (Wistar strain) were dark-adapted for 2 days and then exposed to intense light for 12 hours, and 1, 2, 3, 7, 14, 21, and 28 days. The presence of apoptosis was conf...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0021-5155(99)00011-8
更新日期:1999-05-01 00:00:00
abstract::Changes in the distribution pattern of chloride ions were studied in the embryonic chicken retinal pigment epithelium (RPE), chloride ions being deposited as silver chloride (AgCl) in the RPE and observed by electron microscope. Before the 7th day after fertilization, the chloride ions did not accumulate anywhere in t...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::The purpose of this study is to elucidate the extension of the corneal endothelium onto the iris surface, a condition which has been found in the eyes with rubeosis iridis in various ocular disorders. Histopathology of the anterior chamber angle was studied by electron microscopy in 6 eyes with neovascular glaucoma oc...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract:PURPOSE:To elucidate the characterization of intraocular pressure (IOP) spike after trabeculotomy, and after the combined procedure of phacoemulsification and aspiration (PEA) and intraocular lens (IOL) implantation. METHODS:Included in this study were 39 patients (53 eyes) with primary open-angle glaucoma with IOPs u...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0021-5155(01)00322-7
更新日期:2001-05-01 00:00:00
abstract::Single fiber electromyography (SFEMG) was carried out in the extraocular muscles (EOMs) of 40 adult cats, and the recordings were analyzed. The small fluctuations of the interpotential interval (IPI), so-called "jitter phenomenon", were represented quantitatively as a mean consecutive difference (MCD). The MCD and the...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::Ca movements in mechanical responses of the isolated sphincter and dilator muscles of the rabbit iris to some drugs were studied. D600, a Ca-blocker, was practically ineffective in doses which relax the vascular and intestinal smooth muscles, while other smooth muscle relaxants were effective on the iris muscles in th...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract:PURPOSE:To examine the effects of topical steroid instillation on central corneal thickness in eyes with bullous keratopathy (BK). STUDY DESIGN:Retrospective case series METHODS: Consecutive patients with BK who did not wish to receive corneal transplantation and were treated with 0.1% betamethasone eyedrops were incl...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-019-00658-7
更新日期:2019-05-01 00:00:00
abstract:PURPOSE:To determine the morphological characteristics of the cornea in eyes with posterior corneal vesicles (PCV) determined by in vivo confocal microscopy (IVCM). In addition, to compare the morphological characteristics of the corneas of eyes with PCV to those of eyes with posterior polymorphous corneal dystrophy (P...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-016-0473-x
更新日期:2016-11-01 00:00:00
abstract::A case of unilateral disc-shaped cataract with coloboma of the lens is reported. The patient, a 17-year-old girl, had best corrected visual acuity of 0.01 (+ 9 D) in the right eye and 1.2 in the left eye. Exotropia of 10 Hirschberg degrees was found in her right eye. The visual disturbance of that eye was thought to b...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00