当前位置： SCI文献检索 > JAPANESE JOURNAL OF OPHTHALMOLOGY期刊下所有文献 > Methotrexate-associated orbital lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report.

Methotrexate-associated orbital lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report.

Abstract：

PURPOSE:Lymphoproliferative disorders (LPDs) can develop in patients treated with methotrexate (MTX) and usually respond well to MTX withdrawal. Mucosa-associated lymphoid tissue (MALT) lymphoma is a relatively rare type of MTX-LPD. The development of MTX-LPD in the orbit has not been previously described. We here report a case of orbital MALT lymphoma that disappeared after MTX withdrawal in a patient treated with MTX for rheumatoid arthritis. CASE:A 78-year-old woman who complained of swelling of the left upper eyelid had been treated with MTX for >8 years for rheumatoid arthritis. Slit-lamp examination revealed a temporal subconjunctival mass, salmon pink in color, in the left eye. Fundus photographs also suggested the presence of a temporal tumor in the left orbit. [(18)F]Fluorodeoxyglucose positron emission tomography-computed tomography revealed highly integrated lesions in the left inferotemporal orbit and a left external iliac lymph node, a left obturator lymph node, and an inguinal lymph node. Pathologic analysis of a tumor biopsy specimen showed small- and medium-sized lymphocytes positive for CD20, MIB-1, and bcl-2 and negative for CD10, CD3, bcl-1, IgG4, and EBV-ISH. On the basis of these findings, we diagnosed the tumor as MTX-induced MALT lymphoma. The subconjunctival and orbital masses disappeared gradually over 10 months after MTX withdrawal and did not recur within 2 years. CONCLUSION:This case of orbital MTX-LPD suggests that the possibility of MTX-LPD should be considered even for ocular tumors in patients treated with MTX.

journal_name

Jpn J Ophthalmol

journal_title

Japanese journal of ophthalmology

authors

Kobayashi Y,Kimura K,Fujitsu Y,Shinkawa K,Muta H,Sonoda KH

doi

10.1007/s10384-016-0439-z

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

212-8

issue

3

eissn

0021-5155

issn

1613-2246

pii

10.1007/s10384-016-0439-z

journal_volume

60

pub_type

杂志文章

相关文献

JAPANESE JOURNAL OF OPHTHALMOLOGY文献大全
  • Effect of topical latanoprost-timolol combined therapy on retinal blood flow and circulation of optic nerve head tissue in cynomolgus monkeys.

    abstract：PURPOSE:To evaluate the effects of topical latanoprost and timolol in combined therapy on retinal blood flow and tissue circulation in the optic nerve head (ONH) of the cynomolgus monkey. METHODS:Latanoprost (30 microL, 0.005%) was instilled once daily and timolol (30 microL, 0.5%) twice daily for 6 days into 1 eye, a...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0021-5155(99)00217-8

    authors： Ishii K,Araie M

    更新日期：2000-05-01 00:00:00

  • Comparing central retinal thickness in diabetic macular edema measured by two different spectral-domain optical coherence tomography devices.

    abstract：PURPOSE:We evaluated central retinal thickness (CRT) in diabetic macular edema (DME) using two different spectral-domain (SD) optical coherence tomography (OCT) instruments: the Cirrus and Spectralis OCTs. METHODS:CRT was measured in 63 eyes of 32 patients with DME using both instruments on the same day. RESULTS:CRT ...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-011-0085-4

    authors： Suzuma K,Yamada Y,Liu M,Tsuiki E,Fujikawa A,Kitaoka T

    更新日期：2011-11-01 00:00:00

  • 5-S-cysteinyldopa as diagnostic tumor marker for uveal malignant melanoma.

    abstract：PURPOSE:To evaluate the clinical significance of 5-S-cysteinyldopa (5-S-CD), a major intermediate in melanin synthesis, as a potential diagnostic tumor marker for uveal malignant melanoma. METHODS:The levels of 5-S-CD in the serum were measured by high-performance liquid chromatography in 16 patients with primary uvea...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0021-5155(01)00393-8

    authors： Goto H,Usui M,Wakamatsu K,Ito S

    更新日期：2001-09-01 00:00:00

  • Clinical course of macular edema in two cases of interferon-associated retinopathy observed by optical coherence tomography.

    abstract：BACKGROUND:Interferon (IFN)-associated retinopathy is typically characterized by retinal hemorrhages and cotton wool spots at the posterior fundus, but visual function is usually maintained. With the use of optical coherence tomography (OCT), two patients with IFN-associated retinopathy who had developed macular edema ...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-004-0176-6

    authors： Shimura M,Saito T,Yasuda K,Tamai M

    更新日期：2005-05-01 00:00:00

  • Expression of beta defensins in ocular surface tissue of experimentally developed allergic conjunctivitis mouse model.

    abstract：PURPOSE:To investigate the expression of beta-defensin in the ocular surface of a mouse experimental allergic conjunctivitis (EAC) model. METHODS:Mouse beta-defensin (mBD)-1 and -2 mRNA expressed in conjunctival tissue of both the EAC and the control group were analyzed by real-time reverse transcriptase-polymerase ch...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-005-0262-4

    authors： Ikeda A,Nakanishi Y,Sakimoto T,Shoji J,Sawa M,Nemoto N

    更新日期：2006-01-01 00:00:00

  • The effect of early treatment at the initial stage 3 moderate phase of retinopathy of prematurity on severe retinal changes.

    abstract：PURPOSE:To compare the outcome of early treatment at the initial stage 3 moderate phase of retinopathy of prematurity (ROP) with that at prethreshold ROP. METHODS:The outcome of treatment of 117 very-low-birth-weight infants was reviewed. Sixty-eight infants underwent their first treatment at prethreshold ROP (group A...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-004-0216-2

    authors： Hatsukawa Y,Ueki N,Yamagishi T,Kitajima H

    更新日期：2005-09-01 00:00:00

  • Epidermal nevus syndrome associated with anterior scleral staphyloma and ectopic bone and cartilaginous intraocular tissue.

    abstract：BACKGROUND:Epidermal nevus syndrome encompasses a group of congenital neurocutaneous anomalies characterized by epidermal nevi in association with cerebral, ocular, and skeletal abnormalities. We report herein the case of a Japanese girl with epidermal nevus syndrome associated with complex ocular choristoma and discus...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-009-0760-x

    authors： Miyagawa Y,Nakazawa M,Kudoh T

    更新日期：2010-01-01 00:00:00

  • Single fiber electromyography in cat extraocular muscles.

    abstract：:Single fiber electromyography (SFEMG) was carried out in the extraocular muscles (EOMs) of 40 adult cats, and the recordings were analyzed. The small fluctuations of the interpotential interval (IPI), so-called "jitter phenomenon", were represented quantitatively as a mean consecutive difference (MCD). The MCD and the...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Hattori M,Mimura O,Haruta R,Uyama J,Shimo-Oku M

    更新日期：1986-01-01 00:00:00

  • Usefulness of anterior chamber depth measurement for efficacy assessment of steroid pulse therapy in patients with Vogt-Koyanagi-Harada disease.

    abstract：PURPOSE:To clarify the usefulness of measuring anterior chamber depth by the IOLMaster for early-stage assessment of the therapeutic effect of steroid pulse therapy in patients with Vogt-Koyanagi-Harada (VKH) syndrome with active uveitis. METHODS:Seven patients with VKH syndrome (three men and four women) participated...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-010-0843-8

    authors： Otsuki T,Shimizu K,Igarashi A,Kamiya K

    更新日期：2010-09-01 00:00:00

  • Morphological observations of rat corneal endothelial cells after exposure to ozonated solution.

    abstract：PURPOSE:To determine whether exposure to ozonated solution alters the morphology of corneal endothelial cells in rats and to examine the protective effect of ascorbic acid. METHODS:The anterior chambers of rat eyes were filled with 4 ppm of ozonated solution. Some were left in that state, while others were flushed out...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-008-0629-4

    authors： Suzuki H,Sato S,Murano N,Matsui H,Oharazawa H,Takahashi H

    更新日期：2009-03-01 00:00:00

  • Reconsideration of the most appropriate criterion in the lowest classification of vision disability in Japan.

    abstract：PURPOSE:To verify the current Japanese classification of vision disability in regard to visual acuity. METHODS:A questionnaire was sent to 100 ophthalmology services in Japan. Each service was asked to extract 300 of their outpatient records. From these records, patients who had a sum of corrected visual acuity in bot...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s10384-011-0081-8

    authors： Nishida T,Ando N,Sado K,Nakadomari S

    更新日期：2011-11-01 00:00:00

  • Indocyanine green angiographic findings of lacquer cracks in pathologic myopia.

    abstract：:Lacquer cracks are thought to represent healed mechanical breaks in the retinal pigment epithelium, Bruch's membrane, and choriocapillaris complex. In this study, we analyzed the indocyanine green (ICG) angiographic features of lacquer cracks and compared them with findings using fluorescein angiography. Complete opht...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0021-5155(98)00008-2

    authors： Ohno-Matsui K,Morishima N,Ito M,Tokoro T

    更新日期：1998-07-01 00:00:00

  • A new method for quantification of metamorphopsia in patients with epiretinal membrane

    abstract：:Purpose: We have developed a new method for quantification of metamorphopsia and applied it to study distorted vision resulting from epiretinal membrane (ERM).Patients and Methods: We prepared a modified Amsler chart, which was a square grid formed by black lines on a white background with 12 cm on a side and divided ...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0021-5155(00)00157-x

    authors： Shinoda K,Ishida S,Kawashima S,Matsuzaki T,Yamada K,Katsura H

    更新日期：2000-05-01 00:00:00

  • Evaluation of factors affecting visual acuity after Descemet stripping automated endothelial keratoplasty.

    abstract：PURPOSE:To elucidate the factors affecting visual acuity after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS:We reviewed consecutive patients who underwent primary DSAEK for corneal endothelial dysfunction at Inouye Eye Hospital from January 2010 through January 2015 and who had a follow-up of...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-016-0491-8

    authors： Amano S,Setogawa A,Inoue K

    更新日期：2017-03-01 00:00:00

  • Visualization of microaneurysms using optical coherence tomography angiography: comparison of OCTA en face, OCT B-scan, OCT en face, FA, and IA images.

    abstract：PURPOSE:To compare the visualization of microaneurysms (MAs) in patients with diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA) with that using fluorescein angiography (FA). STUDY DESIGN:Prospective, clinical, and experimental. METHODS:This study was a prospective evaluation of imaging t...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-018-0570-0

    authors： Hamada M,Ohkoshi K,Inagaki K,Ebihara N,Murakami A

    更新日期：2018-03-01 00:00:00

  • Cancer in relatives of retinoblastoma patients.

    abstract：:Medical histories with emphasis on malignant disease were obtained on 1,269 first and second degree relatives of 93 probands with retinoblastoma and on 671 first and second degree relatives of 50 age-matched control children. The number of nonocular malignancies expected to occur in first and second degree relatives o...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Cohen MS,Augsburger JJ,Shields JA,Amsel J,Felberg NT

    更新日期：1989-01-01 00:00:00

  • Arteriovenous crossing associated with branch retinal vein occlusion.

    abstract：:Branch retinal vein occlusion (BRVO) is defined as the focal occlusion of a first or second-order branch of retinal vein, which occurs most frequently at an arteriovenous (AV) crossing. Direct ophthalmoscopy, color fundus photography, and fluorescein angiography facilitate observation of AV crossings parallel to the r...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章,评审

    doi：10.1007/s10384-019-00676-5

    authors： Muraoka Y,Tsujikawa A

    更新日期：2019-09-01 00:00:00

  • Pseudoexfoliation syndrome in Chinese.

    abstract：:The exfoliation syndrome is thought to be a very rare disease in China. The clinical features of 11 patients with pseudoexfoliation (PE) and the histopathologic changes in specimens affected by PE were studied. The loss of pigment at the pupillary ruff and the dense pigmentation on the trabecular meshwork were the ear...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Ye TC,Mao WS,Zhang J

    更新日期：1989-01-01 00:00:00

  • Early laser photocoagulation for extensive retinal avascularity in infants with incontinentia pigmenti.

    abstract：PURPOSE:To describe the clinical features and treatment outcomes of severe retinopathy in eyes with incontinentia pigmenti (IP) of infants within a few months of birth. STUDY DESIGN:Retrospective clinical study. METHODS:Six eyes of three patients (6-day-old girl, 5-month-old girl, and 14-day-old boy) with IP were exa...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-020-00768-7

    authors： Nakao S,Nishina S,Tanaka S,Yoshida T,Yokoi T,Azuma N

    更新日期：2020-11-01 00:00:00

  • A novel exon 17 deletion mutation of RPGRIP1 gene in two siblings with Leber congenital amaurosis.

    abstract：PURPOSE:To investigate mutations of causal genes in two affected male siblings of a Japanese family with suspected Leber congenital amaurosis (LCA) and to characterize the related clinical features. METHODS:After obtaining informed consent, genomic DNA was extracted from peripheral blood of the proband and his family ...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-014-0339-z

    authors： Suzuki T,Fujimaki T,Yanagawa A,Arai E,Fujiki K,Wada Y,Murakami A

    更新日期：2014-11-01 00:00:00

  • Annual incidences of visual impairment during 10-year period in Mie prefecture, Japan.

    abstract：PURPOSE:To determine the annual incidence of visual impairment in a Japanese population during a 10-year period. METHODS:We examined the physical disability certificates issued yearly between 2004 and 2013 in Mie prefecture, Japan. During this period 2468 visually impaired people were registered under the newly define...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s10384-017-0517-x

    authors： Ikesugi K,Ichio T,Tsukitome H,Kondo M

    更新日期：2017-07-01 00:00:00

  • Light-evoked changes of glycine-like immunoreactivity in the rat retina.

    abstract：:Glycine is an important inhibitory neurotransmitter in the vertebrate retina. Although many reports of glycine localization by the immunocytochemical method have been published, none has distinguished the neurotransmitter function of glycine from metabolic change. If glycine is the neurotransmitter, it seems that it m...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Nishikawa S,Ishiguro S,Tamai M

    更新日期：1996-01-01 00:00:00

  • Effect of topical dorzolamide on tissue circulation in the rabbit optic nerve head.

    abstract：PURPOSE:To examine the effect of 1% topical dorzolamide on tissue circulation in the optic nerve head (ONH) of Dutch rabbits. METHODS:A laser speckle tissue circulation analyzer was used. One eye of each rabbit received 1% topical dorzolamide twice daily for 20 days, and the fellow eye received the vehicle in a masked...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0021-5155(99)00093-3

    authors： Tamaki Y,Araie M,Muta K

    更新日期：1999-09-01 00:00:00

  • The role of fibronectin in corneal wound healing explored by a physician-scientist.

    abstract：:For the past 30 years, I have worked as a physician-scientist in both the clinic and laboratory setting at a number of university medical schools. Encountering patients in the clinic for whom treatment was not available led me to the laboratory in an attempt to develop the appropriate treatment for future patients. Th...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章,评审

    doi：10.1007/s10384-012-0165-0

    authors： Nishida T

    更新日期：2012-09-01 00:00:00

  • Effect of 3,3'-iminodipropionitrile on experimental intravitreal proliferation in albino rabbits.

    abstract：:The effect of 3,3'-iminodipropionitrile (IDPN) on experimental intravitreal proliferation in albino rabbits was studied by light and electron microscopy. About 2.5 x 10(5) tissue cultured fibroblasts were injected into the vitreous cavity of albino rabbits. Immediately after the injection, phosphate-buffered solution ...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Akiyama K

    更新日期：1990-01-01 00:00:00

  • Falciform retinal fold as sign of familial exudative vitreoretinopathy.

    abstract：:We studied family members of 9 patients with falciform retinal fold, and found a number of cases showing features of familial exudative vitreoretinopathy (FEVR) in the fundi. Retinal fold was also seen in the eye of a cousin of the propositus. Three cases with falciform retinal fold were bilateral and 7 cases were uni...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Nishimura M,Yamana T,Sugino M,Kohno T,Yamana Y,Minei M,Sanui H

    更新日期：1983-01-01 00:00:00

  • Augmented expression of CD44 splice variants in lymphoproliferative disorder of the lacrimal gland in Sjögren's syndrome.

    abstract：:We explored the involvement of CD44 isoforms in lymphoproliferative disorder (LPD) of the lacrimal gland of a Sjögren's syndrome patient with unilateral LPD. The CD44 variant with the v6 exon was selectively detected from infiltrating lymphocytes in the gland with LPD, but not from infiltrating lymphocytes in the norm...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0021-5155(97)00072-5

    authors： Hiraoka M,Saito I,Tsubota K,Sugai S,Miyasaka N

    更新日期：1997-09-01 00:00:00

  • Trabeculotomy combined with phacoemulsification, intraocular lens implantation and sinusotomy for exfoliation glaucoma.

    abstract：PURPOSE:To verify the advantages of trabeculotomy combined with phacoemulsification, intraocular lens implantation and sinusotomy (PTOS) in eyes with exfoliation glaucoma (XFG) and a coexisting cataract. PATIENTS AND METHODS:Sixty-six eyes of 62 Japanese XFG patients that received either PTOS, phacotrabeculectomy (PTE...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1007/s10384-011-0024-4

    authors： Fukuchi T,Ueda J,Nakatsue T,Suda K,Hara H,Abe H

    更新日期：2011-05-01 00:00:00

  • Soluble ascorbate free radical reductase in the human lens.

    abstract：:A major and a minor ascorbate free radical (AFR) reductase were separated from the soluble fraction in the human lens cortex by DEAE-cellulose ion-exchange column chromatography. These AFR reductases also exhibited diaphorase activity using dichlorophenolindophenol and ferricyanide as electron acceptors. The major AFR...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Bando M,Obazawa H

    更新日期：1994-01-01 00:00:00

  • Electrophysiological studies of spontaneous retinal degeneration in celestial goldfish (chotengan).

    abstract：:Spontaneous retinal degeneration of Celestial goldfish was studied histologically and electrophysiologically. Retinal degeneration was divided into three stages. Until the age of 75 days (Stage 0) the retina showed normal histological development and the electroretinograms (ERGs) exhibited dominant b-waves similar to ...

    journal_title：Japanese journal of ophthalmology

    pub_type： 杂志文章

    doi：

    authors： Sakaue H,Negi A,Matsumura M,Ohkuma M,Honda Y

    更新日期：1987-01-01 00:00:00