Epidermal nevus syndrome associated with anterior scleral staphyloma and ectopic bone and cartilaginous intraocular tissue.

Abstract:

BACKGROUND:Epidermal nevus syndrome encompasses a group of congenital neurocutaneous anomalies characterized by epidermal nevi in association with cerebral, ocular, and skeletal abnormalities. We report herein the case of a Japanese girl with epidermal nevus syndrome associated with complex ocular choristoma and discuss the histopathological findings. CASE:A mass lesion was noted on the left eyeball of a newborn Japanese girl. The lesion appeared to be a scleral staphyloma. Linear and diffuse acanthoses were also apparent on the face. Skin biopsy revealed an epidermal nevus. Histopathological examination of the enucleated left eyeball demonstrated that extremely thin sclera adjacent to the corneal limbus resulted in anterior staphyloma, and ectopic osteocartilaginous tissues were present in the posterior sclera. CONCLUSION:Epidermal nevus syndrome associated with complex ocular choristoma was diagnosed. The anterior staphylomatous lesion observed in this case has not been reported previously.

journal_name

Jpn J Ophthalmol

authors

Miyagawa Y,Nakazawa M,Kudoh T

doi

10.1007/s10384-009-0760-x

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

15-8

issue

1

eissn

0021-5155

issn

1613-2246

journal_volume

54

pub_type

杂志文章
  • A nontraumatic macular hole in a 10-year-old girl.

    abstract:BACKGROUND:Full-thickness macular holes usually develop in the elderly population. To the best of our knowledge, there has been no written report of a nontraumatic macular hole in a pediatric patient. CASE:A 10-year-old girl noticed decreased central vision in her left eye without any history of trauma. OBSERVATIONS:...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-005-0231-y

    authors: Nakano T,Uemura A,Kanda S,Sakamoto T

    更新日期:2005-11-01 00:00:00

  • Effects of alertness on three-dimensional eye movements.

    abstract:PURPOSE:To investigate effects of alertness on three-dimensional (3D) eye movements. METHODS:During drowsy and alert periods, 3D eye movements were recorded with dual search coils in three normal rhesus monkeys, and in two of these monkeys after placement of bilateral kainic acid lesions of the rostral interstitial nu...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(00)00211-2

    authors: Suzuki Y,Straumann D,Henn V

    更新日期:2000-09-01 00:00:00

  • Eye wall resection in the management of uveal neoplasms.

    abstract::Management of intraocular tumors, specifically uveal melanoma, is a matter of controversy. The treatment of these ocular neoplasms varies from observation to enucleation, irradiation (cobalt plaque and proton-helium particle) and eye wall resection. Over the last 18 years, we have developed two techniques for surgical...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Peyman GA,Gremillion CM

    更新日期:1989-01-01 00:00:00

  • Effects of voxel size on detection of lateral geniculate nucleus activation in functional magnetic resonance imaging.

    abstract:PURPOSE:To study the effect of voxel size on the detection of lateral geniculate nucleus (LGN) activation during visual stimulation using functional magnetic resonance imaging (fMRI) at 1.5 T. METHODS:Ten normal subjects were scanned during visual stimulation with flashing goggles, four times, with four different voxe...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-004-0124-5

    authors: Miki A,Liu CS,Liu GT

    更新日期:2004-11-01 00:00:00

  • Glycosaminoglycans in pterygium tissues and normal conjunctiva.

    abstract::Glycosaminoglycans (GAG) in pterygium tissues were analyzed and the results were compared with those in the normal human conjunctiva. A marked difference in the GAG composition was found: 78% of the total hexosamines of GAG from pterygium was glucosamine, whereas 98% of those of the conjunctiva was galactosamine. Pter...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Kaneko M,Takaku I,Katsura N

    更新日期:1986-01-01 00:00:00

  • Study of effects of antiglaucoma eye drops on N-methyl-D-aspartate-induced retinal damage.

    abstract:PURPOSE:To study the effects of antiglaucoma eye drops on N-methyl-D-aspartate (NMDA)-induced retinal damage. METHODS:Several antiglaucoma eye drops, beta-blockers, alpha/beta-blockers, an alpha1-blocker, an alpha2-agonist, and a prostaglandin derivative, were topically administrated to NMDA-treated rat eyes daily for...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-005-0253-5

    authors: Metoki T,Ohguro H,Ohguro I,Mamiya K,Ito T,Nakazawa M

    更新日期:2005-11-01 00:00:00

  • Photopic negative response of full-field and focal macular electroretinograms in patients with optic nerve atrophy.

    abstract:PURPOSE:To determine alterations of the photopic negative response (PhNR) in the full-field and focal macular electroretinograms (ERGs) of patients with optic nerve atrophy (ONA). METHODS:Ten eyes of eight patients, five women and three men with a mean age of 55.1 years, with ONA were studied. Thirty-six age-matched c...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-009-0731-2

    authors: Tamada K,Machida S,Yokoyama D,Kurosaka D

    更新日期:2009-11-01 00:00:00

  • Single fiber electromyography in cat extraocular muscles.

    abstract::Single fiber electromyography (SFEMG) was carried out in the extraocular muscles (EOMs) of 40 adult cats, and the recordings were analyzed. The small fluctuations of the interpotential interval (IPI), so-called "jitter phenomenon", were represented quantitatively as a mean consecutive difference (MCD). The MCD and the...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Hattori M,Mimura O,Haruta R,Uyama J,Shimo-Oku M

    更新日期:1986-01-01 00:00:00

  • Intracameral and Lenticular Penetration of Locally Applied Deuterium-Labeled Vitamin E in Rats.

    abstract::Purpose: To confirm the intraocular dynamics of 1% deuterium (D) labeled alpha-tocopheral acetate (VEA) solution.Methods: The concentrations of D(3)-VEA and D(3)-alpha-tocopherol (VE) derived from D(3)-VEA in the aqueous humor and lens were measured after instilling 1% D(3)-VEA continuously into the cul-de-sac of rat ...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(00)00315-4

    authors: Nagata M,Kawazu K,Midori Y,Kojima M,Shirasawa E,Sasaki K

    更新日期:2001-01-01 00:00:00

  • Ultrastructural pleomorphism in medulloepithelioma of the ciliary body: a comparative study of tumour cells and fetal ciliary epithelium.

    abstract::A locally aggressive nonteratoid intraocular medulloepithelioma occurring in a two-year-old boy was studied by electron microscopy. For comparison the primitive pars plana region was examined in human fetal eyes obtained at 16, 18 and 22 weeks of gestation. The tumour was polymorphic with neural, intermediate and epit...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Wakakura M,Lee WR

    更新日期:1990-01-01 00:00:00

  • Seasonal variation in myopia progression and axial elongation: an evaluation of Japanese children participating in a myopia control trial.

    abstract:PURPOSE:To investigate the seasonal variations in myopia progression and axial elongation in Japanese children. METHODS:Ninety-two children who were enrolled in a myopia-control trial and wearing single vision or progressive addition lenses were included in the analyses (mean ± SD age 11.4 ± 1.7 years, mean spherical ...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10384-012-0148-1

    authors: Fujiwara M,Hasebe S,Nakanishi R,Tanigawa K,Ohtsuki H

    更新日期:2012-07-01 00:00:00

  • Expression of the Varicella Zoster Virus Thymidine Kinase and Cytokines in Patients with Acute Retinal Necrosis Syndrome.

    abstract::Purpose: Acute retinal necrosis (ARN) is caused by varicella zoster virus (VZV) infection. In this study, we investigated the activity of this virus and expressions of some cytokines.Patients and Methods: The expressionof VZV thymidine kinase and some cytokines were investigated by reverse transcriptase-polymerase cha...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(00)00254-9

    authors: Sato M,Abe T,Tamai M

    更新日期:2000-11-01 00:00:00

  • Argon laser iridotomy and surgical iridectomy in treatment of primary angle-closure glaucoma.

    abstract::In an attempt to compare surgical peripheral iridectomy and laser iridotomy with regards to the long-term control of the intraocular pressure (IOP), analyses were carried out of the clinical records of 195 eyes of 149 primary angle-closure glaucoma patients who had undergone either peripheral iridectomy or laser irido...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Go FJ,Akiba Y,Yamamoto T,Kitazawa Y

    更新日期:1984-01-01 00:00:00

  • Comparison of two different spectral domain optical coherence tomography devices in the detection of localized retinal nerve fiber layer defects.

    abstract:PURPOSE:To compare the detection of localized retinal nerve fiber layer (RNFL) defects by two different spectral domain optical coherence tomography (SD-OCT) devices. METHODS:Eyes of 42 normal control subjects and 48 patients with a localized RNFL defect on red-free fundus photographs were imaged by the Cirrus (Carl Z...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-013-0239-7

    authors: Kim KE,Ahn SJ,Kim DM

    更新日期:2013-07-01 00:00:00

  • A novel biomarker for increased intracranial pressure in idiopathic intracranial hypertension.

    abstract:PURPOSE:Changes in optic disc and peripapillary structures associated with optic nerve edema in idiopathic intracranial hypertension (IIH), can be evaluated with spectral domain optical coherence tomography (SD-OCT). We aimed to evaluate the association between increased cerebrospinal fluid (CSF) opening pressure and c...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-020-00807-3

    authors: Bingöl Kızıltunç P,Atilla H

    更新日期:2021-01-09 00:00:00

  • Scientific Reviewers.

    abstract:: ...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1007/s10384-018-0627-0

    authors:

    更新日期:2018-11-01 00:00:00

  • Association of an age-related maculopathy susceptibility 2 gene variant with the 12-month outcomes of intravitreal aflibercept combined with photodynamic therapy for polypoidal choroidal vasculopathy.

    abstract:PURPOSE:To determine the association of age-related maculopathy susceptibility 2 (ARMS2) gene polymorphisms with the 12-month outcomes of intravitreal aflibercept combined with photodynamic therapy (IVA+PDT) in polypoidal choroidal vasculopathy (PCV). STUDY DESIGN:Interventional cohort study. METHODS:This was a retro...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-019-00683-6

    authors: Nakai S,Matsumiya W,Miki A,Honda S,Nakamura M

    更新日期:2019-09-01 00:00:00

  • Ocular findings in a patient with Prader-Willi syndrome.

    abstract::A 25-year-old woman is described whose clinical features included infantile hypotonia, obesity after infancy, intellectual impairment, dysmorphic facial features, short stature, small hands and feet, and abnormal dentition, which are typical of the Prader-Willi syndrome. The patient had almond-shaped eyes, spot-like h...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Wang XC,Norose K,Kiyosawa K,Segawa K

    更新日期:1995-01-01 00:00:00

  • The quality of life in patients with pathologic myopia.

    abstract:PURPOSE:To evaluate the functional status in daily life and the quality of life (QOL) of pathologic myopia patients. METHODS:A cross-sectional study was conducted using data of consecutive pathologic myopia patients (n = 200) and control subjects (n = 144). The influence of the disease on the daily life and the QOL of...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(00)00305-1

    authors: Takashima T,Yokoyama T,Futagami S,Ohno-Matsui K,Tanaka H,Tokoro T,Mochizuki M

    更新日期:2001-01-01 00:00:00

  • Predictors of postoperative binocularity in adult strabismus.

    abstract::We evaluated postoperative binocularity in a retrospective study of 111 adult strabismus patients in order to identify the factors which influence the success of surgery for horizontal concomitant strabismus in adults. Selection criteria included minimum age of 15 years at time of surgery, and preoperative fusion impa...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(97)00076-2

    authors: Umazume F,Ohtsuki H,Hasebe S

    更新日期:1997-11-01 00:00:00

  • Studies of eye lens in poikilothermal animals. III. Long-term incubation of rainbow trout lenses.

    abstract::Long-term incubation of the lens of rainbow trout, a cold water fish, can be carried out at 0 degrees C, without altering its transparency. This is not possible in mammalian lenses. Rainbow trout lenses maintained their transparency with normal cation levels for 2.5 months in H10 medium, which is a simple balanced sal...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Hikida M,Iwata S

    更新日期:1986-01-01 00:00:00

  • Synaptic inputs from superior colliculus to vertical eye movement motoneurons in the cat.

    abstract::The superior colliculus (SC) plays an important role in the transformation of visual and auditory signals into motor commands to generate saccadic eye movements toward the targets. This study investigated the synaptic input patterns from the SC, into vertical eye movement-related superior and inferior rectus motoneuro...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Sasaki Y,Matsui H,Tamai A

    更新日期:1994-01-01 00:00:00

  • Presumed drusen of optic nerve head in siblings with Usher syndrome.

    abstract::Two siblings with Usher syndrome had optic disc mulberry tumors that were photographically documented over a 5-year period. During this period, growth of these tumors was demonstrated. These lesions were reported histologically to be drusen. The existence of presumed optic disc drusen in siblings with Usher syndrome m...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Shiono T,Noro M,Tamai M

    更新日期:1991-01-01 00:00:00

  • Prevalence of superior segmental optic nerve hypoplasia in Korea.

    abstract:PURPOSE:To investigate the prevalence of superior segmental optic nerve hypoplasia in Korea. METHODS:We reviewed the fundus photographs of 3905 individuals who were 40 years old or older and who participated in the comprehensive medical examination program at the Health Promotion Center of Seoul National University Bu...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-009-0663-x

    authors: Han SB,Park KH,Kim DM,Kim TW

    更新日期:2009-05-01 00:00:00

  • Effect of topical steroid instillation on central corneal thickness in eyes with bullous keratopathy.

    abstract:PURPOSE:To examine the effects of topical steroid instillation on central corneal thickness in eyes with bullous keratopathy (BK). STUDY DESIGN:Retrospective case series METHODS: Consecutive patients with BK who did not wish to receive corneal transplantation and were treated with 0.1% betamethasone eyedrops were incl...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-019-00658-7

    authors: Ono T,Iwasaki T,Yukawa C,Mori Y,Nejima R,Tokunaga T,Amano S,Miyata K

    更新日期:2019-05-01 00:00:00

  • Detection of HIV-RNA in aqueous humor and subretinal fluid in an HIV carrier with rhegmatogenous retinal detachment.

    abstract:BACKGROUND:Although human immunodeficiency virus (HIV)-related ocular complexes are commonly observed in acquired immune deficiency syndrome (AIDS) patients, it has not been previously reported that HIV had already invaded the ocular tissues of HIV carriers. CASE:A 56-year-old woman was diagnosed as having rhegmatogen...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(00)00278-1

    authors: Kashiwagi K,Gohdo T,Sato S,Iijima H,Tsukahara S

    更新日期:2000-11-01 00:00:00

  • Upregulation of matrix metalloproteinase in tear fluid of patients with recurrent corneal erosion.

    abstract:PURPOSE:To investigate gelatinase [matrix metalloproteinase (MMP)-2 and MMP-9] expression in the tear fluid of patients with recurrent corneal erosion (RCE). METHODS:Eleven patients with RCE, three patients with traumatic corneal erosion, and 10 control individuals were enrolled in this study. Tear samples from RCE ey...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-007-0455-0

    authors: Sakimoto T,Shoji J,Yamada A,Sawa M

    更新日期:2007-09-01 00:00:00

  • A multicenter study of typical retinitis pigmentosa in Japan.

    abstract::A nationwide, multicenter study of typical retinitis pigmentosa was carried out in collaboration with 13 university hospitals throughout Japan. A total of 253 patients, 122 males and 131 females, with a wide range of ages (mean 48 years), were registered during a two-month period in 1989. Determination of inheritance ...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Hayakawa M,Matsumura M,Ohba N,Matsui M,Fujiki K,Kanai A,Tamai M,Shiono T,Tokoro T,Akazawa Y

    更新日期:1993-01-01 00:00:00

  • Clinical characteristics and outcomes of open globe injuries in Japan.

    abstract:PURPOSE:To describe the epidemiology and clinical outcomes of open globe injuries (OGIs) in Japan over 10 years, and examine preoperative factors influencing the visual prognosis after surgery. STUDY DESIGN:Retrospective, observational, multicenter case-series study. METHODS:Patients' data were entered into a compute...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s10384-018-0638-x

    authors: Okamoto Y,Morikawa S,Okamoto F,Inomoto N,Ishikawa H,Ueda T,Sakamoto T,Sugitani K,Oshika T

    更新日期:2019-01-01 00:00:00

  • Comparison of Yatabe-Guilford personality test results in retinitis pigmentosa and glaucoma patients.

    abstract:PURPOSE:To determine the psychological state and personality traits of patients with retinitis pigmentosa (RP) or glaucoma so that a closer and better relationship can be developed with the patients. METHODS:The Yatabe-Guilford personality test was administered to 75 RP patients and 42 glaucoma patients. The latter gr...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(02)00621-4

    authors: Igarashi Y,Sato E,Ito A,Miyauchi O,Ikejiri M,Hanawa T,Tsuyama Y,Mizota A,Fujimoto N,Adachi-Usami E

    更新日期:2003-01-01 00:00:00