Early laser photocoagulation for extensive retinal avascularity in infants with incontinentia pigmenti.

abstract：PURPOSE:To clarify the usefulness of measuring anterior chamber depth by the IOLMaster for early-stage assessment of the therapeutic effect of steroid pulse therapy in patients with Vogt-Koyanagi-Harada (VKH) syndrome with active uveitis. METHODS:Seven patients with VKH syndrome (three men and four women) participated...

journal_title：Japanese journal of ophthalmology

authors： Otsuki T,Shimizu K,Igarashi A,Kamiya K

更新日期：2010-09-01 00:00:00

abstract：:Purpose: To confirm the intraocular dynamics of 1% deuterium (D) labeled alpha-tocopheral acetate (VEA) solution.Methods: The concentrations of D(3)-VEA and D(3)-alpha-tocopherol (VE) derived from D(3)-VEA in the aqueous humor and lens were measured after instilling 1% D(3)-VEA continuously into the cul-de-sac of rat ...

journal_title：Japanese journal of ophthalmology

authors： Nagata M,Kawazu K,Midori Y,Kojima M,Shirasawa E,Sasaki K

更新日期：2001-01-01 00:00:00

abstract：:A case of bilateral retinoblastoma affecting both of a pair of dizygotic twins was reported. To our knowledge, there has been only one previous report of dizygotic twins, both affected, with this disease. The present twins had no family history of retinoblastoma. They were born prematurely as extremely low birth weigh...

journal_title：Japanese journal of ophthalmology

authors： Amino K,Ichioka I,Ichioka H,Matsubara K,Lin YW,Ohta S

更新日期：1992-01-01 00:00:00

abstract：:We studied the inhibitory effects of chicken egg white ovomacroglobulin, a broad-spectrum protease inhibitor, and a synthetic protease inhibitory peptide, Bz-GFR-O-mercaptoanilide, on the growth of two strains of Serratia marcescens in a synthetic medium. The growth of the virulent protease-producing strain, S. marces...

journal_title：Japanese journal of ophthalmology

authors： Miyagawa S,Matsumoto K,Kamata R,Okamura R,Maeda H

更新日期：1991-01-01 00:00:00

abstract：:S-antigen (S-Ag), a well characterized 45-kDa protein in the photoreceptor cells, induces predominantly T-cell-mediated autoimmune uveitis when injected into experimental animals. Recently, we have shown that native histone H3 protein derived from yeast (Saccharomyces cerevisiae), or a synthetic peptide that is homolo...

journal_title：Japanese journal of ophthalmology

authors： Singh VK,Usukura J,Shinohara T

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:Remodeling of the extracellular matrix occurs in the lamina cribrosa in progressed glaucomatous optic nerve damage including disc cupping. We examined immunohistochemical changes in the transforming growth factor (TGF)-beta and platelet-derived growth factor (PDGF) in the optic nerve head in an experimentally i...

journal_title：Japanese journal of ophthalmology

authors： Fukuchi T,Ueda J,Hanyu T,Abe H,Sawaguchi S

更新日期：2001-11-01 00:00:00

abstract：PURPOSE:To investigate cytokine mRNA expression during the inflammatory process induced in the contralateral eyes by uniocular inoculation of herpes simplex virus type 1 (HSV-1) via the anterior chamber. METHODS:BALB/c mice were inoculated in the anterior chamber with 5 x 10(4) plaque-forming units of HSV-1 (KOS). mRN...

journal_title：Japanese journal of ophthalmology

authors： Saitoh-Ishibashi K,Ishibashi K,Azumi A,Negi A

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:To determine the association of age-related maculopathy susceptibility 2 (ARMS2) gene polymorphisms with the 12-month outcomes of intravitreal aflibercept combined with photodynamic therapy (IVA+PDT) in polypoidal choroidal vasculopathy (PCV). STUDY DESIGN:Interventional cohort study. METHODS:This was a retro...

journal_title：Japanese journal of ophthalmology

authors： Nakai S,Matsumiya W,Miki A,Honda S,Nakamura M

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To study the effects of antiglaucoma eye drops on N-methyl-D-aspartate (NMDA)-induced retinal damage. METHODS:Several antiglaucoma eye drops, beta-blockers, alpha/beta-blockers, an alpha1-blocker, an alpha2-agonist, and a prostaglandin derivative, were topically administrated to NMDA-treated rat eyes daily for...

journal_title：Japanese journal of ophthalmology

authors： Metoki T,Ohguro H,Ohguro I,Mamiya K,Ito T,Nakazawa M

更新日期：2005-11-01 00:00:00

abstract：:Three cases of medullated nerve fibers of the retina were seen. They had medullated nerve fibers in both the upper and lower quadrants of the temporal retina, whereby the temporal raphe of the retinal nerve fiber layer could be visualized. Some nerve fibers from the upper and lower quadrants crossed each other on the ...

journal_title：Japanese journal of ophthalmology

authors： Sakai T,Sano K,Tsuzuki K,Ueno M,Kawamura Y

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:To survey the changes in indications for penetrating keratoplasty (PKP) and re-evaluate the risk factors for allograft rejection and graft failure. METHODS:We evaluated the records of 396 eyes of 335 patients who had undergone PKP at the Tokyo University Hospital between 1987 and 1997. Clinical results were an...

journal_title：Japanese journal of ophthalmology

authors： Inoue K,Amano S,Oshika T,Sawa M,Tsuru T

更新日期：2000-03-01 00:00:00

abstract：PURPOSE:Diabetes mellitus aggravates carotid occlusive disease, that can manifest as ocular ischemic syndrome (OIS). Ocular manifestations and visual prognosis of OIS in diabetic patients were retrospectively analyzed. METHODS:Twenty-three consecutive diabetic patients with OIS were divided into two groups according t...

journal_title：Japanese journal of ophthalmology

authors： Ino-ue M,Azumi A,Kajiura-Tsukahara Y,Yamamoto M

更新日期：1999-01-01 00:00:00

abstract：PURPOSE:To determine the efficacy of real-time PCR for the diagnosis and prognosis of varicella-zoster virus (VZV) keratitis. STUDY DESIGN:Retrospective case series. METHODS:Patients: 545 consecutive patients with keratitis were examined to quantify copy numbers of VZV DNA by real-time PCR. Association of copy number...

journal_title：Japanese journal of ophthalmology

authors： Inata K,Miyazaki D,Uotani R,Shimizu D,Miyake A,Shimizu Y,Inoue Y

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:To evaluate the effect of tetramethylpyrazine on the elevation of aqueous flare and intraocular pressure (IOP) induced by prostaglandin (PG) E(2) and PGE(2) receptor (EP) agonists. METHODS:PGE(2) or EP agonists (11-deoxy PGE(1), EP(2) agonist; 17-phenyl trinor PGE(2), EP(1) and EP(3) agonist; or sulprostone, E...

journal_title：Japanese journal of ophthalmology

authors： Kitagawa K,Hayasaka S,Nagaki Y,Watanabe K

更新日期：2001-05-01 00:00:00

abstract：PURPOSE:Defensins are antimicrobial peptides and are classified into three groups, alpha-, beta- and theta-defensins. We investigated the localization of human neutrophil peptides (HNP) 1-3, which are members of the alpha-defensin subfamily, and the expression of human beta-defensin 1 (hBD-1) and hBD-2 in the ocular su...

journal_title：Japanese journal of ophthalmology

authors： Ikeda A,Sakimoto T,Shoji J,Sawa M

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:To evaluate cases with a retinal pigment epithelium (RPE) aperture using polarization-sensitive optical coherence tomography (PS-OCT). STUDY DESIGN:Retrospective consecutive case series. METHODS:A retrospective study that included three eyes (three patients) with RPE aperture and age-related macular degenerat...

journal_title：Japanese journal of ophthalmology

authors： Obata R,Yoshinaga A,Yamamoto M,Komatsu K,Aoki N,Yamanari M,Sugiyama S,Minami T,Azuma K,Inoue T,Aihara M,Kato S

更新日期：2020-11-10 00:00:00

abstract：PURPOSE:To determine the spatial distribution types of macular pigment (MP) in elderly Japanese individuals and to consider their origin. STUDY DESIGN:Observational case series. METHODS:Local MP optical density (MPOD) at some eccentricities and MP volume were measured using the MPOD module of a MultiColor Spectralis ...

journal_title：Japanese journal of ophthalmology

authors： Obana A,Gohto Y,Sasano H,Gellermann W,Sharifzadeh M,Seto T,Bernstein PS

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:To investigate the process of repair in the epithelial cells and the reconstruction in lens fibers of a mouse lens that has developed opacity because of a large-scale perforating injury. METHODS:Lenses of 4-week-old mice were perforated with a needle through the cornea to induce the development of traumatic ca...

journal_title：Japanese journal of ophthalmology

authors： Hirayama S,Wakasugi A,Morita T,Sakai Y,Mukuno K,Uga S,Shimizu K

更新日期：2003-07-01 00:00:00

abstract：PURPOSE:To evaluate the effects of anti-alphabeta T cell receptor monoclonal antibody (R73) on the induction of experimental autoimmune uveoretinitis (EAU) in rats. METHODS:Lewis rats in which EAU was induced were treated with R73. All rats were examined for the clinical course of EAU, pathological findings of the glo...

journal_title：Japanese journal of ophthalmology

authors： Inoki T,Yamagami S,Sakai R,Isobe M,Tsuru T,Kawashima H

更新日期：2002-09-01 00:00:00

abstract：PURPOSE:Sweet's syndrome (SS) is a skin disorder clinically characterized by fever, neutrophilia, and painful edematous plaques that occasionally causes posterior uveitis. We present two cases of SS with panuveitis resembling Behçet's disease (BD). SUBJECTS:Two patients with panuveitis associated with SS. OBSERVATION...

journal_title：Japanese journal of ophthalmology

authors： Matsumiya W,Kusuhara S,Yamada Y,Azumi A,Negi A

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:Lymphoproliferative disorders (LPDs) can develop in patients treated with methotrexate (MTX) and usually respond well to MTX withdrawal. Mucosa-associated lymphoid tissue (MALT) lymphoma is a relatively rare type of MTX-LPD. The development of MTX-LPD in the orbit has not been previously described. We here repo...

journal_title：Japanese journal of ophthalmology

authors： Kobayashi Y,Kimura K,Fujitsu Y,Shinkawa K,Muta H,Sonoda KH

更新日期：2016-05-01 00:00:00

abstract：:We have adapted intrinsic signal optical imaging of neural activity to the noninvasive functional imaging of the retina. Results to date demonstrate the feasibility and potential of this new method of functional assessment of the retina. In response to visual stimuli, we have imaged reflectance changes in the retina t...

journal_title：Japanese journal of ophthalmology

authors： Ts'o D,Schallek J,Kwon Y,Kardon R,Abramoff M,Soliz P

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:To compare the outcome of early treatment at the initial stage 3 moderate phase of retinopathy of prematurity (ROP) with that at prethreshold ROP. METHODS:The outcome of treatment of 117 very-low-birth-weight infants was reviewed. Sixty-eight infants underwent their first treatment at prethreshold ROP (group A...

journal_title：Japanese journal of ophthalmology

authors： Hatsukawa Y,Ueki N,Yamagishi T,Kitajima H

更新日期：2005-09-01 00:00:00

abstract：:Medical histories with emphasis on malignant disease were obtained on 1,269 first and second degree relatives of 93 probands with retinoblastoma and on 671 first and second degree relatives of 50 age-matched control children. The number of nonocular malignancies expected to occur in first and second degree relatives o...

journal_title：Japanese journal of ophthalmology

authors： Cohen MS,Augsburger JJ,Shields JA,Amsel J,Felberg NT

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:To evaluate the safety of retrocorneal plaque aspiration in patients with fungal keratitis. STUDY DESIGN:Retrospective study. METHODS:A retrospective case series of fungal keratitis seen at Kyoto Prefectural University of Medicine between November 2013 and September 2018. Patients with retrocorneal plaque who...

journal_title：Japanese journal of ophthalmology

authors： Kitazawa K,Fukuoka H,Inatomi T,Aziza Y,Kinoshita S,Sotozono C

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:We retrospectively investigated the efficacy of corneal crosslinking (CXL) on progressive keratoconus in a Japanese population and compared the outcomes of conventional and accelerated CXL. STUDY DESIGN:A retrospective cohort study METHODS: A total of 108 consecutive eyes in 95 patients (75 men; 21.9 ± 6.2 yea...

journal_title：Japanese journal of ophthalmology

authors： Kato N,Konomi K,Shinzawa M,Kasai K,Ide T,Toda I,Sakai C,Negishi K,Tsubota K,Shimazaki J

更新日期：2018-09-01 00:00:00

abstract：:A 76-year-old Japanese woman had suffered from fatigue, weight loss, and cutaneous hyperpigmentation at the age of 38 years and was diagnosed as having tuberculous Addison's disease. Since then, corticosteroids had been administered effectively as hormonal replacement. At the age of 75 years, the patient presented wit...

journal_title：Japanese journal of ophthalmology

authors： Kakiuchi T,Uehara F,Ohba N

更新日期：1998-09-01 00:00:00

abstract：PURPOSE:The purpose of this study was to estimate the optimal size of visual field test for detecting longitudinal changes in retinitis pigmentosa (RP) by dividing the visual field. METHODS:We reviewed the results of 10° static visual field tests in 19 eyes of 19 RP patients. Sixty-eight numeric value points were divi...

journal_title：Japanese journal of ophthalmology

authors： Ogino K,Otani A,Oishi A,Kurimoto M,Sekiya T,Yoshimura N

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To compare the progression of posterior vitreous detachment (PVD) during aging among eyes of diabetics with diabetic retinopathy (DR), eyes of diabetics without DR, and eyes of nondiabetics. STUDY DESIGN:Prospective cross-sectional study. METHODS:One-hundred thirty-three diabetic eyes with DR (DR group), 254 ...

journal_title：Japanese journal of ophthalmology

authors： Hayashi K,Sato T,Manabe SI,Hirata A,Yoshimura K

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:Vogt-Koyanagi-Harada (VKH) disease is known to have varied manifestations in different ethnic groups. In order to analyze the clinical profile of VKH cases in the Indian population, we studied 87 consecutive cases of VKH disease treated in an uveitis clinic in South India between 1985 and 1996. METHODS:Retrosp...

journal_title：Japanese journal of ophthalmology

authors： Mondkar SV,Biswas J,Ganesh SK

更新日期：2000-05-01 00:00:00