Tear film break-up time evaluated by real-time Hartmann-Shack wavefront sensing.

Abstract:

PURPOSE:To develop a novel method for measuring tear break-up time (BUT) by continuously measuring higher order wavefront aberrations using a Hartmann-Shack (H-S) aberrometer. METHODS:Wavefront aberrations up to the sixth order for a 4-mm pupil were measured in six eyes of six normal subjects using an H-S aberrometer. The aberrometry was performed once every second for up to 50 s under topical anesthesia. The sequence of the points was divided into two stages, and the BUT was defined as the wavefront border of the stages (WFBUT). The WFBUT was compared with the BUT by the conventional fluorescein method (FLBUT) or by the disruption of placid-ring images (PLBUT). RESULTS:In three eyes, the WFBUT (average, 10.9 +/- 1.1 s) was shorter than the PLBUT (average, 17.5 +/- 2.5 s), while in the other three eyes the WFBUT (average, 21.5 +/- 2.2 s) was longer than PLBUT (average, 8.1 +/- 2.2 s). The FLBUT was shorter than WFBUT or PLBUT in most cases. CONCLUSIONS:The tear break-up time measured by H-S aberrometer may be used as a practical measure of tear break-up.

journal_name

Jpn J Ophthalmol

authors

Mihashi T,Hirohara Y,Koh S,Ninomiya S,Maeda N,Fujikado T

doi

10.1007/s10384-005-0289-6

subject

Has Abstract

pub_date

2006-03-01 00:00:00

pages

85-9

issue

2

eissn

0021-5155

issn

1613-2246

journal_volume

50

pub_type

杂志文章
  • Histochemical studies of the separation of the lens vesicle in the mouse.

    abstract::Histochemical studies were carried out in the mouse on the changes and distribution patterns of glycosaminoglycan molecular species during the separation of the lens vesicle. To obtain embryos, pregnant mice of the Jcl:ICR strain were sacrificed on day 10.5 or 11 of pregnancy. Serial frontal sections were strained wit...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Mizuno S,Ikeda K,Hirabayashi Y

    更新日期:1995-01-01 00:00:00

  • A new method for quantification of metamorphopsia in patients with epiretinal membrane.

    abstract:PURPOSE:A new method for quantification of metamorphopsia was applied to study distorted vision in patients with epiretinal membrane. METHOD:Sixty-three patients with unilateral epiretinal membrane in the macula were examined. A modified Amsler chart (a grid of black lines on a white background measuring 12 x 12 cm wi...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(00)00173-8

    authors: Shinoda K,Ishida S,Kawashima S,Matsuzaki T,Yamada K,Katsura H

    更新日期:2000-07-01 00:00:00

  • Long-term retention of dye after indocyanine green-assisted internal limiting membrane peeling.

    abstract:PURPOSE:To evaluate dye retention in the fundus after indocyanine green (ICG)-assisted internal limiting membrane peeling. METHODS:Ten eyes with stage 3 or 4 nondiabetic idiopathic macular hole (MH group) and six eyes with diffuse diabetic macular edema (DM group) were studied. The fundus was examined with 780-nm infr...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-006-0325-1

    authors: Ashikari M,Ozeki H,Tomida K,Sakurai E,Tamai K,Ogura Y

    更新日期:2006-07-01 00:00:00

  • Myopia control trial with progressive addition lenses in Japanese schoolchildren: baseline measures of refraction, accommodation, and heterophoria.

    abstract:PURPOSE:To describe baseline measures of refraction, accommodation, and heterophoria in Japanese schoolchildren enrolled in a randomized clinical trial that examines whether progressive addition lenses slow myopic progression compared with single-focus lenses. METHODS:Ninety-five children with myopia between -1.25 and...

    journal_title:Japanese journal of ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s10384-004-0131-6

    authors: Hasebe S,Nonaka F,Nakatsuka C,Ohtsuki H

    更新日期:2005-01-01 00:00:00

  • Takayasu disease on the centenary of its discovery.

    abstract::Takayasu disease was first reported in 1908 by Mikito Takayasu as "a case of peculiar changes in the central retinal vessels." Because in these patients the pulse of the radial artery is impalpable, investigations focusing on the ischemic symptoms of the upper body were conducted. In 1948, Shimizu and Sano named this ...

    journal_title:Japanese journal of ophthalmology

    pub_type: 传,历史文章,杂志文章

    doi:10.1007/s10384-009-0650-2

    authors: Sugiyama K,Ijiri S,Tagawa S,Shimizu K

    更新日期:2009-03-01 00:00:00

  • Clinical and angiographic characteristics of retinal manifestations in cat scratch disease.

    abstract:PURPOSE:To elucidate clinical and angiographic features of retinal manifestations in cat scratch disease. METHODS:Clinical characteristics as well as fluorescein and indocyanine green (ICG) angiographic features were reviewed in 4 consecutive patients with retinal manifestations caused by serologically confirmed cat s...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(99)00195-1

    authors: Matsuo T,Yamaoka A,Shiraga F,Takasu I,Okanouchi T,Nagayama M,Baba T,Hayashi M,Sarada K

    更新日期:2000-03-01 00:00:00

  • Imaging of a retinal pigment epithelium aperture using polarization-sensitive optical coherence tomography.

    abstract:PURPOSE:To evaluate cases with a retinal pigment epithelium (RPE) aperture using polarization-sensitive optical coherence tomography (PS-OCT). STUDY DESIGN:Retrospective consecutive case series. METHODS:A retrospective study that included three eyes (three patients) with RPE aperture and age-related macular degenerat...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-020-00787-4

    authors: Obata R,Yoshinaga A,Yamamoto M,Komatsu K,Aoki N,Yamanari M,Sugiyama S,Minami T,Azuma K,Inoue T,Aihara M,Kato S

    更新日期:2020-11-10 00:00:00

  • Association between clinical diagnostic tests and health-related quality of life surveys in patients with dry eye syndrome.

    abstract:PURPOSE:This study was performed to assess the impact of dry eye on patients' quality of life (QOL) and to analyze the association between subjective symptoms and ocular surface findings of dry eye. METHODS:The study population consisted of 158 patients with dry eye aged 20 years or older who visited any of the 15 med...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s10384-010-0812-2

    authors: Mizuno Y,Yamada M,Miyake Y,Dry Eye Survey Group of the National Hospital Organization of Japan.

    更新日期:2010-07-01 00:00:00

  • Pharmacokinetics of topically applied ciprofloxacin in rabbit tears.

    abstract::Fluoroquinolones provide an important single antibiotic therapy for bacterial keratitis caused by Staphylococcus aureus and numerous gram-negative bacteria, including Pseudomonas aeruginosa. The pharmacokinetics of three ocular fluoroquinolones, norfloxacin (CHIBOXIN, Merck, Sharp & Dohme), ciprofloxacin (CILOXAN, Alc...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Green LC,Callegan MC,Engel LS,Shimomura Y,Jasheway DW,O'Callaghan RJ,Hill JM

    更新日期:1996-01-01 00:00:00

  • Mutation c. 1142 del G in the PRPF31 gene in a family with autosomal dominant retinitis pigmentosa (RP11) and its implications.

    abstract:PURPOSE:To identify a mutation in the PRPF31 gene in a family (Family K) with autosomal dominant retinitis pigmentosa (adRP) linked to 19q13.4 (RP11) and to find the frequency of mutations in the PRPF31 gene among Japanese families with adRP. METHODS:Genomic DNA specimens were prepared from five symptomatic and two as...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-006-0394-1

    authors: Taira K,Nakazawa M,Sato M

    更新日期:2007-01-01 00:00:00

  • A 10-year review of penetrating keratoplasty.

    abstract:PURPOSE:To survey the changes in indications for penetrating keratoplasty (PKP) and re-evaluate the risk factors for allograft rejection and graft failure. METHODS:We evaluated the records of 396 eyes of 335 patients who had undergone PKP at the Tokyo University Hospital between 1987 and 1997. Clinical results were an...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(99)00190-2

    authors: Inoue K,Amano S,Oshika T,Sawa M,Tsuru T

    更新日期:2000-03-01 00:00:00

  • Retinal pigment epithelium folds as a diagnostic finding of Vogt-Koyanagi-Harada disease.

    abstract:OBJECTIVE:To examine using the folds of the retinal pigment epithelium (RPE) to diagnose Vogt-Koyanagi-Harada (VKH) disease. METHODS:Retrospective clinical review of 57 Japanese patients between July 2005 and April 2009. Optical coherence tomography (OCT), fundus photographs and fluorescein angiography (FA) were studi...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-012-0212-x

    authors: Kato Y,Yamamoto Y,Tabuchi H,Fukushima A

    更新日期:2013-01-01 00:00:00

  • A case of frosted branch angiitis with yellowish-white placoid lesions: fluorescein and indocyanine green angiography findings.

    abstract::Severe, white sheathing of the retinal vessels and yellowish-white placoid lesions, suggesting frosted-branch angiitis, were found in both fundi of a 24-year-old woman. Fluorescein angiography showed hypofluorescence of the placoid lesions in the early phase and hyperfluorescence in the late phase. Indocyanine green a...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(98)00045-8

    authors: Masuda K,Ueno M,Watanabe I

    更新日期:1998-11-01 00:00:00

  • A Case of Reversed Ophthalmic Artery Flow without Occlusion of the Internal Carotid Artery.

    abstract::Background: We report a case of reversed ophthalmic artery (OA) flow showing neither occlusion of the internal carotid artery (ICA) nor ophthalmic symptoms.Case: An 82-year-old man had transient blindness in both eyes. After left carotid endarterectomy, ophthalmic symptoms improved in the right and left eyes. Afterwar...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(00)00244-6

    authors: Souma N,Tasaka Y,Nakauchi K,Kubota Y,Amano Y,Sogabe T

    更新日期:2000-09-01 00:00:00

  • Argon laser iridotomy and surgical iridectomy in treatment of primary angle-closure glaucoma.

    abstract::In an attempt to compare surgical peripheral iridectomy and laser iridotomy with regards to the long-term control of the intraocular pressure (IOP), analyses were carried out of the clinical records of 195 eyes of 149 primary angle-closure glaucoma patients who had undergone either peripheral iridectomy or laser irido...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Go FJ,Akiba Y,Yamamoto T,Kitazawa Y

    更新日期:1984-01-01 00:00:00

  • Serous macular detachment associated with retinal arterial macroaneurysm.

    abstract:PURPOSE:To report optical coherence tomography (OCT) findings of macular edema secondary to retinal arterial macroaneurysms. METHODS:Six eyes with retinal arterial macroaneurysms were retrospectively examined by OCT. All eyes had macular edema without massive macular hemorrhage. Fluorescein angiography was performed i...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-006-0347-0

    authors: Takahashi K,Kishi S

    更新日期:2006-09-01 00:00:00

  • Epidermal nevus syndrome associated with anterior scleral staphyloma and ectopic bone and cartilaginous intraocular tissue.

    abstract:BACKGROUND:Epidermal nevus syndrome encompasses a group of congenital neurocutaneous anomalies characterized by epidermal nevi in association with cerebral, ocular, and skeletal abnormalities. We report herein the case of a Japanese girl with epidermal nevus syndrome associated with complex ocular choristoma and discus...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-009-0760-x

    authors: Miyagawa Y,Nakazawa M,Kudoh T

    更新日期:2010-01-01 00:00:00

  • Study of effects of antiglaucoma eye drops on N-methyl-D-aspartate-induced retinal damage.

    abstract:PURPOSE:To study the effects of antiglaucoma eye drops on N-methyl-D-aspartate (NMDA)-induced retinal damage. METHODS:Several antiglaucoma eye drops, beta-blockers, alpha/beta-blockers, an alpha1-blocker, an alpha2-agonist, and a prostaglandin derivative, were topically administrated to NMDA-treated rat eyes daily for...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-005-0253-5

    authors: Metoki T,Ohguro H,Ohguro I,Mamiya K,Ito T,Nakazawa M

    更新日期:2005-11-01 00:00:00

  • Evaluation of factors affecting visual acuity after Descemet stripping automated endothelial keratoplasty.

    abstract:PURPOSE:To elucidate the factors affecting visual acuity after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS:We reviewed consecutive patients who underwent primary DSAEK for corneal endothelial dysfunction at Inouye Eye Hospital from January 2010 through January 2015 and who had a follow-up of...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-016-0491-8

    authors: Amano S,Setogawa A,Inoue K

    更新日期:2017-03-01 00:00:00

  • Comparison of Yatabe-Guilford personality test results in retinitis pigmentosa and glaucoma patients.

    abstract:PURPOSE:To determine the psychological state and personality traits of patients with retinitis pigmentosa (RP) or glaucoma so that a closer and better relationship can be developed with the patients. METHODS:The Yatabe-Guilford personality test was administered to 75 RP patients and 42 glaucoma patients. The latter gr...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(02)00621-4

    authors: Igarashi Y,Sato E,Ito A,Miyauchi O,Ikejiri M,Hanawa T,Tsuyama Y,Mizota A,Fujimoto N,Adachi-Usami E

    更新日期:2003-01-01 00:00:00

  • The relationship between visual disability and visual scores in patients with retinitis pigmentosa.

    abstract:PURPOSE:To evaluate the relationship between visual disability and visual scores in patients with retinitis pigmentosa. METHODS:The relationship between visual disability and visual scores (visual acuity and visual field) was investigated in 93 patients with retinitis pigmentosa. The visual disability of each patient ...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(99)00171-9

    authors: Sumi I,Matsumoto S,Okajima O,Shirato S

    更新日期:2000-01-01 00:00:00

  • A nontraumatic macular hole in a 10-year-old girl.

    abstract:BACKGROUND:Full-thickness macular holes usually develop in the elderly population. To the best of our knowledge, there has been no written report of a nontraumatic macular hole in a pediatric patient. CASE:A 10-year-old girl noticed decreased central vision in her left eye without any history of trauma. OBSERVATIONS:...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-005-0231-y

    authors: Nakano T,Uemura A,Kanda S,Sakamoto T

    更新日期:2005-11-01 00:00:00

  • Long-term outcome of systemic cyclosporine treatment following penetrating keratoplasty.

    abstract:PURPOSE:To perform a retrospective study to evaluate the long-term outcome of systemic cyclosporine treatment as an adjunct to topical corticosteroid treatment after penetrating keratoplasty (PKP). METHODS:Twenty-six high-risk patients (27 eyes) who received systemic cyclosporine following PKP for an average of 5.4 mo...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(01)00339-2

    authors: Inoue K,Kimura C,Amano S,Sato T,Fujita N,Kagaya F,Kaji Y,Tsuru T,Araie M

    更新日期:2001-07-01 00:00:00

  • Proteomic analysis of rat retina in a steroid-induced ocular hypertension model: potential vulnerability to oxidative stress.

    abstract:PURPOSE:To investigate global protein expression profiles in the retinas of normal and glucocorticoid-induced ocular hypertensive rats by proteomic analysis. METHODS:Ocular hypertension was induced by topical application of dexamethasone (DEX) for 4 weeks. Age-matched untreated rats served as controls. Intraocular pre...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-007-0507-5

    authors: Miyara N,Shinzato M,Yamashiro Y,Iwamatsu A,Kariya KI,Sawaguchi S

    更新日期:2008-03-01 00:00:00

  • Tenon advancement and duplication technique to prevent postoperative Ahmed valve tube exposure in patients with refractory glaucoma.

    abstract:PURPOSE:To present and compare the long-term results of Dr. Tamcelik's previously described technique of Tenon advancement and duplication with the conventional Ahmed glaucoma valve (AGV) implantation technique in patients with refractory glaucoma. METHODS:This study was a multicenter, retrospective case series that i...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s10384-013-0249-5

    authors: Tamcelik N,Ozkok A,Sarıcı AM,Atalay E,Yetik H,Gungor K

    更新日期:2013-07-01 00:00:00

  • Effects of N-demethylated carbachol on intraocular pressure and pupil in ocular hypertensive patients.

    abstract::The effects of N-demethylated carbachol on intraocular pressure and pupil size were studied in 18 ocular hypertensive patients. Topical administration of N-demethylated carbachol in 9%, 15% and 30% solutions has been demonstrated to bring about miosis which was found to be dose-dependent. No significant change of intr...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Kitazawa Y,Shirato S

    更新日期:1982-01-01 00:00:00

  • Comparison of two procedures: photorefractive keratectomy versus laser in situ keratomileusis for low to moderate myopia.

    abstract:PURPOSE:A prospective study was conducted to compare the effectiveness, safety, and stability of photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) for correction of low to moderate myopia. METHODS:Forty-five patients with a manifest refraction (PRK, -4.54 +/- 0.80; LASIK, -4.82 +/- 1.10) from ...

    journal_title:Japanese journal of ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0021-5155(01)00406-3

    authors: Lee JB,Kim JS,Choe C,Seong GJ,Kim EK

    更新日期:2001-09-01 00:00:00

  • Comparison between refractive outcomes between macula-on and macula-off retinal detachments after phaco-vitrectomy.

    abstract:PURPOSE:To evaluate axial length (AL) measurements and refractive outcomes in vitrectomy combined with cataract operation for rhegmatogenous retinal detachment (RRD) with wholly detached macula. STUDY DESIGN:Retrospective, consecutive, comparative, clinical study. METHODS:We reviewed the data of patients treated by v...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-019-00667-6

    authors: Pak KY,Park KH,Park SW,Byon IS,Lee JE

    更新日期:2019-07-01 00:00:00

  • Transient intraocular pressure elevation after trabeculotomy and its occurrence with phacoemulsification and intraocular lens implantation.

    abstract:PURPOSE:To elucidate the characterization of intraocular pressure (IOP) spike after trabeculotomy, and after the combined procedure of phacoemulsification and aspiration (PEA) and intraocular lens (IOL) implantation. METHODS:Included in this study were 39 patients (53 eyes) with primary open-angle glaucoma with IOPs u...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(01)00322-7

    authors: Inatani M,Tanihara H,Muto T,Honjo M,Okazaki K,Kido N,Honda Y

    更新日期:2001-05-01 00:00:00

  • The quality of life in patients with pathologic myopia.

    abstract:PURPOSE:To evaluate the functional status in daily life and the quality of life (QOL) of pathologic myopia patients. METHODS:A cross-sectional study was conducted using data of consecutive pathologic myopia patients (n = 200) and control subjects (n = 144). The influence of the disease on the daily life and the QOL of...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(00)00305-1

    authors: Takashima T,Yokoyama T,Futagami S,Ohno-Matsui K,Tanaka H,Tokoro T,Mochizuki M

    更新日期:2001-01-01 00:00:00