Experimental autoimmune uveoretinitis (EAU) in rats: abrogation of resistance to the induction and augmentation of the inflammation by pertussis toxin.

abstract：PURPOSE:In a previous study we demonstrated that the progression of the disease retinitis pigmentosa (RP) can be readily monitored by the mean deviation (MD) measured by Humphrey central 10-2 perimetry, which assesses the sensitivity distribution in the macular area in eyes affected by RP. In the present study, we inve...

journal_title：Japanese journal of ophthalmology

authors： Abe K,Iijima H,Hirakawa H,Tsukahara Y,Toda Y

更新日期：2002-09-01 00:00:00

abstract：:The superior colliculus (SC) plays an important role in the transformation of visual and auditory signals into motor commands to generate saccadic eye movements toward the targets. This study investigated the synaptic input patterns from the SC, into vertical eye movement-related superior and inferior rectus motoneuro...

journal_title：Japanese journal of ophthalmology

authors： Sasaki Y,Matsui H,Tamai A

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:The aims of the study were to detect early changes in the optic nerve function of patients with Graves' orbitopathy (GrO) who do not have any signs and symptoms of optic neuropathy, using pattern visual evoked potentials (P-VEP), and investigate any possible relation between the disease activity and P-VEP P100 ...

journal_title：Japanese journal of ophthalmology

authors： Acaroğlu G,Simşek T,Ozalp S,Mutluay A

更新日期：2003-09-01 00:00:00

abstract：:Conventional vitreoretinal surgery for proliferative vitreoretinopathy is unsatisfactory despite numerous innovations over the past 20 years. Silicone oil injections in this series resulted in 70% reattachment of these end-stage cases, but within twelve months over 90% had no useful visual result. The development of a...

journal_title：Japanese journal of ophthalmology

authors： Constable I

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:To describe the epidemiology and clinical outcomes of open globe injuries (OGIs) in Japan over 10 years, and examine preoperative factors influencing the visual prognosis after surgery. STUDY DESIGN:Retrospective, observational, multicenter case-series study. METHODS:Patients' data were entered into a compute...

journal_title：Japanese journal of ophthalmology

authors： Okamoto Y,Morikawa S,Okamoto F,Inomoto N,Ishikawa H,Ueda T,Sakamoto T,Sugitani K,Oshika T

更新日期：2019-01-01 00:00:00

abstract：:We evaluated postoperative binocularity in a retrospective study of 111 adult strabismus patients in order to identify the factors which influence the success of surgery for horizontal concomitant strabismus in adults. Selection criteria included minimum age of 15 years at time of surgery, and preoperative fusion impa...

journal_title：Japanese journal of ophthalmology

authors： Umazume F,Ohtsuki H,Hasebe S

更新日期：1997-11-01 00:00:00

abstract：PURPOSE:To study the effects of epigenetic events on corneal barrier functions, we examined tight junctions (TJs), the most important factor in the barrier function of the cornea, by using in vitro and in vivo corneal trauma models. METHODS:We examined alteration of TJ-associated gene expression and corneal barrier fu...

journal_title：Japanese journal of ophthalmology

authors： Nishikiori N,Sawada N,Ohguro H

更新日期：2008-05-01 00:00:00

abstract：:Histochemical studies were carried out in the mouse on the changes and distribution patterns of glycosaminoglycan molecular species during the separation of the lens vesicle. To obtain embryos, pregnant mice of the Jcl:ICR strain were sacrificed on day 10.5 or 11 of pregnancy. Serial frontal sections were strained wit...

journal_title：Japanese journal of ophthalmology

authors： Mizuno S,Ikeda K,Hirabayashi Y

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:To measure choroidal thickness in healthy pregnant women using enhanced depth imaging optical coherence tomography (EDI-OCT) and compare the measurements with those of healthy non-pregnant women. METHODS:Choroidal thickness was measured at the fovea and at 3 mm superior, inferior, temporal, and nasal to the fo...

journal_title：Japanese journal of ophthalmology

authors： Takahashi J,Kado M,Mizumoto K,Igarashi S,Kojo T

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To investigate the frequency of infraorbital nerve enlargement (IONE) in orbital lymphoproliferative disorders, and to show that IONE can contribute to the clinical diagnosis of IgG4-related orbital diseases (IgG4-ROD). SUBJECTS AND METHODS:71 cases in which orbital lymphoproliferative disorders were diagnosed...

journal_title：Japanese journal of ophthalmology

authors： Ohshima K,Sogabe Y,Sato Y

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:We investigated by in vivo confocal microscopy alterations in the subepithelial nerve plexus in different types of herpes simplex keratitis (HSK). METHODS:Seventeen patients (seven women and ten men, mean age 63.9 years) with a history of HSK were classified into three groups according to the classification of...

journal_title：Japanese journal of ophthalmology

authors： Nagasato D,Araki-Sasaki K,Kojima T,Ideta R,Dogru M

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:To establish a rat glaucoma model with chronic intraocular pressure (IOP) elevation induced by microbeads suspended in sodium sulfate-sodium hyaluronate. METHODS:Chronic elevation of IOP was induced unilaterally by injecting polystyrene microbeads, suspended in 4 % sodium sulfate and 3 % sodium hyaluronate, in...

journal_title：Japanese journal of ophthalmology

authors： Matsumoto Y,Kanamori A,Nakamura M,Negi A

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:To determine the relationship between apoptotic photoreceptor cell death and the duration of light exposure. METHODS:Ten-week-old male albino rats (Wistar strain) were dark-adapted for 2 days and then exposed to intense light for 12 hours, and 1, 2, 3, 7, 14, 21, and 28 days. The presence of apoptosis was conf...

journal_title：Japanese journal of ophthalmology

authors： Aonuma H,Yamazaki R,Watanabe I

更新日期：1999-05-01 00:00:00

abstract：:We reported previously familial hypo-retinol-binding proteinemia in a child who developed keratomalacia during measles infection. In the present study, we characterized serum retinol-binding proteins (RBPs) in the affected family members and compared these RBPs with those in the unaffected family members. Immunoblotti...

journal_title：Japanese journal of ophthalmology

authors： Matsuo T,Matsuo N

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To investigate the changes in the electrolyte and protein concentrations in the vitreous of 3-week-old chicks with form-deprivation myopia (FDM). METHODS:FDM was induced in 2-day-old male white leghorn chicks by covering the left eye with a translucent plastic goggle and leaving the right eye uncovered to serv...

journal_title：Japanese journal of ophthalmology

authors： Seko Y,Shimokawa H,Pang J,Tokoro T

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:To establish with negative electroretinogram (ERG) the clinical entity of eight patients with unilateral severe photophobia, essentially normal fundus, good visual acuity, and severe cone and rod dysfunction. STUDY DESIGN:Multicenter retrospective observation case series. METHODS:Comprehensive ophthalmologic ...

journal_title：Japanese journal of ophthalmology

authors： Hirakata T,Fujinami K,Saito W,Kanda A,Hirakata A,Ishida S,Murakami A,Tsunoda K,Miyake Y

更新日期：2020-11-12 00:00:00

abstract：PURPOSE:To compare the visualization of microaneurysms (MAs) in patients with diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA) with that using fluorescein angiography (FA). STUDY DESIGN:Prospective, clinical, and experimental. METHODS:This study was a prospective evaluation of imaging t...

journal_title：Japanese journal of ophthalmology

authors： Hamada M,Ohkoshi K,Inagaki K,Ebihara N,Murakami A

更新日期：2018-03-01 00:00:00

abstract：:Medical histories with emphasis on malignant disease were obtained on 1,269 first and second degree relatives of 93 probands with retinoblastoma and on 671 first and second degree relatives of 50 age-matched control children. The number of nonocular malignancies expected to occur in first and second degree relatives o...

journal_title：Japanese journal of ophthalmology

authors： Cohen MS,Augsburger JJ,Shields JA,Amsel J,Felberg NT

更新日期：1989-01-01 00:00:00

abstract：:Ca movements in mechanical responses of the isolated sphincter and dilator muscles of the rabbit iris to some drugs were studied. D600, a Ca-blocker, was practically ineffective in doses which relax the vascular and intestinal smooth muscles, while other smooth muscle relaxants were effective on the iris muscles in th...

journal_title：Japanese journal of ophthalmology

authors： Takayanagi I,Kaneko M,Hisayama T

更新日期：1983-01-01 00:00:00

abstract：PURPOSE:To determine alterations of the photopic negative response (PhNR) in the full-field and focal macular electroretinograms (ERGs) of patients with optic nerve atrophy (ONA). METHODS:Ten eyes of eight patients, five women and three men with a mean age of 55.1 years, with ONA were studied. Thirty-six age-matched c...

journal_title：Japanese journal of ophthalmology

authors： Tamada K,Machida S,Yokoyama D,Kurosaka D

更新日期：2009-11-01 00:00:00

abstract：:The exfoliation syndrome is thought to be a very rare disease in China. The clinical features of 11 patients with pseudoexfoliation (PE) and the histopathologic changes in specimens affected by PE were studied. The loss of pigment at the pupillary ruff and the dense pigmentation on the trabecular meshwork were the ear...

journal_title：Japanese journal of ophthalmology

authors： Ye TC,Mao WS,Zhang J

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:To compare endothelial damage of the donor cornea in relation to the method of inserting the donor cornea into the recipient anterior chamber during Descemet-stripping automated endothelial keratoplasty (DSAEK). METHODS:Fifteen enucleated pig eyes were used. The donor corneoscleral buttons were mounted in an a...

journal_title：Japanese journal of ophthalmology

authors： Hwang H,Kim M

更新日期：2009-09-01 00:00:00

abstract：:The effect of stimulus contrast changes on the binocular visual evoked response (VER) was investigated using pattern reversal VER, dichoptic stimulation, and Fast Fourier Transform. When the stimulus contrast was changed binocularly, the monocular components increased as the contrast increased. The binocular component...

journal_title：Japanese journal of ophthalmology

authors： Katsumi O,Oguchi Y,Kawara T,Peli E

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Epidermal nevus syndrome encompasses a group of congenital neurocutaneous anomalies characterized by epidermal nevi in association with cerebral, ocular, and skeletal abnormalities. We report herein the case of a Japanese girl with epidermal nevus syndrome associated with complex ocular choristoma and discus...

journal_title：Japanese journal of ophthalmology

authors： Miyagawa Y,Nakazawa M,Kudoh T

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:To assess the changes in the size of muscle fibers and the composition of myosin heavy chain (MyHC) isoforms in the global layer (GL) and the orbital layer (OL) of rabbit rectus extraocular muscle (EOM) after recession. METHODS:The right superior rectus muscles of two rabbits were harvested at 3 days or 1, 2, ...

journal_title：Japanese journal of ophthalmology

authors： Park SC,Kim YT,Kim SA,Oh SY

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:This study examines the impact of cataracts on health-related quality of life (HR-QOL) and health events in the older population. METHODS:The study population consisted of 439 unoperated cataract patients aged 60 years or older who visited any of the facilities affiliated with the Cataract Survey Group of the ...

journal_title：Japanese journal of ophthalmology

authors： Yamada M,Mizuno Y,Miyake Y,Cataract Survey Group of the National Hospital Organization of Japan.

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:To determine whether the time course of average visual recovery (visual gain curve) after vitrectomy for different macular diseases can be described by a mathematical function. METHODS:The medical records of 1951 eyes that underwent vitrectomy for different macular diseases such as macular hole, epiretinal mem...

journal_title：Japanese journal of ophthalmology

authors： Kumagai K,Ogino N,Larson E

更新日期：2011-03-01 00:00:00

abstract：:Fibronectin (FN) has been detected at the site of corneal wounds. To investigate whether FN is supplied by the cornea itself or by extracorneal sources, we cultured small blocks of rabbit cornea in vitro with and without autologous serum (5%). The sliding rate of epithelial cells was determined and localization of FN ...

journal_title：Japanese journal of ophthalmology

authors： Nishida T,Nakagawa S,Ohashi Y,Awata T,Manabe R

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:To evaluate changes in conjunctival-scleral thickness following strabismus surgery with anterior segment optical coherence tomography (AS-OCT). STUDY DESIGN:Prospective, observational, consecutive case series. METHODS:Distances between the conjunctival epithelium and inner scleral wall were measured with AS-O...

journal_title：Japanese journal of ophthalmology

authors： Suzuki H,Hikoya A,Komori M,Inagaki R,Haseoka T,Arai S,Takagi Y,Hotta Y,Sato M

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:To evaluate the effect of tetramethylpyrazine on the elevation of aqueous flare and intraocular pressure (IOP) induced by prostaglandin (PG) E(2) and PGE(2) receptor (EP) agonists. METHODS:PGE(2) or EP agonists (11-deoxy PGE(1), EP(2) agonist; 17-phenyl trinor PGE(2), EP(1) and EP(3) agonist; or sulprostone, E...

journal_title：Japanese journal of ophthalmology

authors： Kitagawa K,Hayasaka S,Nagaki Y,Watanabe K

更新日期：2001-05-01 00:00:00