Effects and distribution of intravitreally or subretinally injected silicone oil identified in rabbit retina using osmium tetroxide method.

abstract：PURPOSE:To establish a rat glaucoma model with chronic intraocular pressure (IOP) elevation induced by microbeads suspended in sodium sulfate-sodium hyaluronate. METHODS:Chronic elevation of IOP was induced unilaterally by injecting polystyrene microbeads, suspended in 4 % sodium sulfate and 3 % sodium hyaluronate, in...

journal_title：Japanese journal of ophthalmology

authors： Matsumoto Y,Kanamori A,Nakamura M,Negi A

更新日期：2014-05-01 00:00:00

abstract：:Purpose: We investigated the relationship between the progression of visual field defect and clinical factors in patients with normal-tension glaucoma (NTG).Subjects and Methods: Forty-eight eyes of 48 NTG patients undergoing more than 5-year follow-up were enrolled in this study. Their visual field defects ranged bet...

journal_title：Japanese journal of ophthalmology

authors： Tanaka C,Yamazaki Y,Yokoyama H

更新日期：2001-01-01 00:00:00

abstract：:Purpose: We have developed a new method for quantification of metamorphopsia and applied it to study distorted vision resulting from epiretinal membrane (ERM).Patients and Methods: We prepared a modified Amsler chart, which was a square grid formed by black lines on a white background with 12 cm on a side and divided ...

journal_title：Japanese journal of ophthalmology

authors： Shinoda K,Ishida S,Kawashima S,Matsuzaki T,Yamada K,Katsura H

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:To determine alterations of the photopic negative response (PhNR) in the full-field and focal macular electroretinograms (ERGs) of patients with optic nerve atrophy (ONA). METHODS:Ten eyes of eight patients, five women and three men with a mean age of 55.1 years, with ONA were studied. Thirty-six age-matched c...

journal_title：Japanese journal of ophthalmology

authors： Tamada K,Machida S,Yokoyama D,Kurosaka D

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:To determine whether photoreceptor degeneration in transgenic (Tg) rabbits carrying the Pro347Leu rhodopsin mutation alters the neural activity of the middle and inner retinal neurons. METHODS:Multifocal electroretinograms (mfERGs) were recorded from eight 12-week-old Tg rabbits both before and after intravitr...

journal_title：Japanese journal of ophthalmology

authors： Yokoyama D,Machida S,Kondo M,Terasaki H,Nishimura T,Kurosaka D

更新日期：2010-09-01 00:00:00

abstract：:The exfoliation syndrome is thought to be a very rare disease in China. The clinical features of 11 patients with pseudoexfoliation (PE) and the histopathologic changes in specimens affected by PE were studied. The loss of pigment at the pupillary ruff and the dense pigmentation on the trabecular meshwork were the ear...

journal_title：Japanese journal of ophthalmology

authors： Ye TC,Mao WS,Zhang J

更新日期：1989-01-01 00:00:00

abstract：:The effects of three sulfhydryl agents on the cytoskeletal systems of cultured human trabecular cells were examined by the immunofluorescence method. Incubation with iodoacetamide or N-ethyl maleimide (10(-6) M, 10(-5) M, and 10(-4) M) caused a marked alteration on the actin and microtubule organization, but had littl...

journal_title：Japanese journal of ophthalmology

authors： Iwamoto Y,Tamura M,Nakatsuka K,Yamanouchi U

更新日期：1989-01-01 00:00:00

abstract：:We explored the involvement of CD44 isoforms in lymphoproliferative disorder (LPD) of the lacrimal gland of a Sjögren's syndrome patient with unilateral LPD. The CD44 variant with the v6 exon was selectively detected from infiltrating lymphocytes in the gland with LPD, but not from infiltrating lymphocytes in the norm...

journal_title：Japanese journal of ophthalmology

authors： Hiraoka M,Saito I,Tsubota K,Sugai S,Miyasaka N

更新日期：1997-09-01 00:00:00

abstract：:The enzyme 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNPase) is one of the important markers for myelin synthesis or demyelination. We measured the CNPase activities in the visual pathway tissues of Lewis strain rats with experimental allergic encephalomyelitis (EAE) induced by inoculation of myelin basic protein f...

journal_title：Japanese journal of ophthalmology

authors： Matsushima S,Machi N,Marumo M,Mizuno A

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:To compare the cytotoxicity of povidone-iodine solution (PVP-I) with that of polyvinyl alcohol-iodine solution (PAI) for ophthalmic use. METHODS:Cells of the human corneal epithelial cell line HCE-T were exposed to various dilutions of PVP-I or PAI, and the cytotoxicity of these two antiseptics was evaluated. ...

journal_title：Japanese journal of ophthalmology

authors： Shibata Y,Tanaka Y,Tomita T,Taogoshi T,Kimura Y,Chikama T,Kihira K

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Full-thickness macular holes usually develop in the elderly population. To the best of our knowledge, there has been no written report of a nontraumatic macular hole in a pediatric patient. CASE:A 10-year-old girl noticed decreased central vision in her left eye without any history of trauma. OBSERVATIONS:...

journal_title：Japanese journal of ophthalmology

authors： Nakano T,Uemura A,Kanda S,Sakamoto T

更新日期：2005-11-01 00:00:00

abstract：: ...

journal_title：Japanese journal of ophthalmology

authors：

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:To investigate the prevalence of superior segmental optic nerve hypoplasia in Korea. METHODS:We reviewed the fundus photographs of 3905 individuals who were 40 years old or older and who participated in the comprehensive medical examination program at the Health Promotion Center of Seoul National University Bu...

journal_title：Japanese journal of ophthalmology

authors： Han SB,Park KH,Kim DM,Kim TW

更新日期：2009-05-01 00:00:00

abstract：:Using polymerase chain reaction, we detected the varicella-zoster virus genome in the vitreous humor of two patients with clinically diagnosed acute retinal necrosis. One of the two cases was thought to be caused by infection with a varicella-zoster virus lacking a PstI cleavage site. We could not find any clinical di...

journal_title：Japanese journal of ophthalmology

authors： Mochizuki K,Matsushita H,Hiramatsu Y,Yanagida K

更新日期：1998-05-01 00:00:00

abstract：:The effect of 3,3'-iminodipropionitrile (IDPN) on experimental intravitreal proliferation in albino rabbits was studied by light and electron microscopy. About 2.5 x 10(5) tissue cultured fibroblasts were injected into the vitreous cavity of albino rabbits. Immediately after the injection, phosphate-buffered solution ...

journal_title：Japanese journal of ophthalmology

authors： Akiyama K

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Although air bags have been shown to reduce the number of fatalities and serious injuries caused by motor vehicle accidents, there have been many reports of air bag-related ocular injuries. We recently treated air bag-related corneal laceration in a patient wearing eyeglasses at the time of a motor accident....

journal_title：Japanese journal of ophthalmology

authors： Tsuda Y,Wakiyama H,Amemiya T

更新日期：1999-05-01 00:00:00

abstract：PURPOSE:To verify, by use of data collected by the Japan Glaucoma Society Survey of Bleb-related Infection (JGSSBI), that bleb morphology changes within 12 months of the development of bleb-related infection. METHODS:JGSSBI data from 57 eyes of 57 patients with primary open-angle glaucoma and normal tension glaucoma w...

journal_title：Japanese journal of ophthalmology

authors： Sawada A,Kuwayama Y,Yamamoto T

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:Topical mitomycin C (MMC) administration is reportedly effective in treating ocular surface neoplasms such as squamous cell carcinoma. We treated a case of ocular epithelial dysplasia that had spread too diffusely to be completely removed. We examined the ultrastructure of and c-met (hepatocyte growth factor re...

journal_title：Japanese journal of ophthalmology

authors： Saika S,Miyamoto T,Kawashima Y,Jinza K,Okada Y,Yamanaka O,Ohnishi Y,Ooshima A

更新日期：2000-11-01 00:00:00

abstract：PURPOSE:The purpose of this study was to estimate the optimal size of visual field test for detecting longitudinal changes in retinitis pigmentosa (RP) by dividing the visual field. METHODS:We reviewed the results of 10° static visual field tests in 19 eyes of 19 RP patients. Sixty-eight numeric value points were divi...

journal_title：Japanese journal of ophthalmology

authors： Ogino K,Otani A,Oishi A,Kurimoto M,Sekiya T,Yoshimura N

更新日期：2013-05-01 00:00:00

abstract：:Three cases of medullated nerve fibers of the retina were seen. They had medullated nerve fibers in both the upper and lower quadrants of the temporal retina, whereby the temporal raphe of the retinal nerve fiber layer could be visualized. Some nerve fibers from the upper and lower quadrants crossed each other on the ...

journal_title：Japanese journal of ophthalmology

authors： Sakai T,Sano K,Tsuzuki K,Ueno M,Kawamura Y

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:We report here a patient with bilateral papillomacular retinoschisis with an enlarged glaucomatous optic nerve head cup and a focal lamina cribrosa defect, the findings of our clinical investigations of this case, and the chosen treatment and outcome. DESIGN:This is an observational case report. METHODS:Clini...

journal_title：Japanese journal of ophthalmology

authors： Yoshitake T,Nakanishi H,Setoguchi Y,Kuroda K,Amemiya K,Taniguchi M,Otani A

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:To assess whether the outcomes of toric intraocular lens (IOL) implantation in eyes with oblique astigmatism can be improved by direct measurements of posterior corneal astigmatism using anterior segment optical coherence tomography (AS-OCT) instead of by using anterior corneal measurements alone. STUDY DESIGN...

journal_title：Japanese journal of ophthalmology

authors： Nakano S,Iida M,Hasegawa Y,Hiraoka T,Oshika T

更新日期：2021-01-28 00:00:00

abstract：PURPOSE:To evaluate the cycloplegic effect of mixed eye drops containing 0.5% tropicamide and 0.5% phenylephrine in myopic children, and to determine whether their efficacy was associated with their clinical characteristics. METHODS:Eighty-one myopic children (age, mean +/- SD, 11.0 +/- 1.5 years; mean spherical equiv...

journal_title：Japanese journal of ophthalmology

authors： Hamasaki I,Hasebe S,Kimura S,Miyata M,Ohtsuki H

更新日期：2007-03-01 00:00:00

abstract：:The protective effect of geraniin (tannin from Geranium thunbergii) against oxidative damage was examined in the mouse ocular lens. Oxidative damage in the lens was induced by diamide, diazene dicarboxylic acid bis (N,N-dimethylamide); diamide oxidized the sulfhydryl groups in both the membrane and cytoplasm but did n...

journal_title：Japanese journal of ophthalmology

authors： Fukaya Y,Nakazawa K,Okuda T,Iwata S

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To examine the correlation between the van Herick system and the Shaffer system in a large-scale epidemiological survey conducted on healthy Japanese subjects. METHODS:The van Herick technique was performed on 14,779 subjects aged 40 years and over who participated in an ophthalmic epidemiological survey condu...

journal_title：Japanese journal of ophthalmology

authors： Kashiwagi K,Tokunaga T,Iwase A,Yamamoto T,Tsukahara S

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:To identify any possible determinants in the development of uveitis in leprosy patients. METHODS:Human leukocyte antigen (HLA) class I and II antigen, and HLA class II genotypings were analyzed among Japanese leprosy patients. Ninety-three unrelated Japanese leprosy patients (46 patients with a history of uvei...

journal_title：Japanese journal of ophthalmology

authors： Joko S,Numaga J,Maeda H

更新日期：1999-03-01 00:00:00

abstract：:Distribution of microglia cells was studied in the normal retina of Wistar rats kept in a specific-pathogen-free condition, using a combined technique of light and electron microscopy with the weak silver carbonate staining method of del Rio-Hortega. Typical microglia cells were found mainly in the inner plexiform lay...

journal_title：Japanese journal of ophthalmology

authors： Kohno T,Inomata H,Taniguchi Y

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:To compare the clinical significance of the photopic negative response (PhNRs) elicited by different stimuli from glaucomatous eyes. STUDY DESIGN:Single-center observational study METHOD: Eighty-four eyes of 84 patients with open angle glaucoma (OAG) and 40 eyes of 40 normal subjects were studied. Cone electro...

journal_title：Japanese journal of ophthalmology

authors： Hara Y,Machida S,Ebihara S,Ishizuka M,Tada A,Nishimura T

更新日期：2020-03-01 00:00:00

abstract：:A nationwide, multicenter study of typical retinitis pigmentosa was carried out in collaboration with 13 university hospitals throughout Japan. A total of 253 patients, 122 males and 131 females, with a wide range of ages (mean 48 years), were registered during a two-month period in 1989. Determination of inheritance ...

journal_title：Japanese journal of ophthalmology

authors： Hayakawa M,Matsumura M,Ohba N,Matsui M,Fujiki K,Kanai A,Tamai M,Shiono T,Tokoro T,Akazawa Y

更新日期：1993-01-01 00:00:00

abstract：:The superior colliculus (SC) plays an important role in the transformation of visual and auditory signals into motor commands to generate saccadic eye movements toward the targets. This study investigated the synaptic input patterns from the SC, into vertical eye movement-related superior and inferior rectus motoneuro...

journal_title：Japanese journal of ophthalmology

authors： Sasaki Y,Matsui H,Tamai A

更新日期：1994-01-01 00:00:00