Knockdown of AXL receptor tyrosine kinase in osteosarcoma cells leads to decreased proliferation and increased apoptosis.

abstract：:Information about the impacts of disasters on health is useful for establishing hazard prediction maps and action plans of disaster management. This study aims at learning effective asthma management from the volcano disaster of Mount Asama eruption in Japan on September 1, 2004. We conducted a cross-sectional study t...

journal_title：International journal of immunopathology and pharmacology

authors： Shimizu Y,Dobashi K,Hisada T,Ono A,Todokoro M,Iijima H,Utsugi M,Kakegawa S,Iizuka K,Ishizuka T,Morikawa A,Mori M

更新日期：2007-04-01 00:00:00

abstract：:Paraneoplastic sensitive neuropathy is one of the most common presentations among a group of cancer-related disorders known as Paraneoplastic Neurological Syndromes (PNS). PNS likely have an autoimmune etiology since they have been associated with the presence of antibodies against neuronal antigens expressed by tumor...

journal_title：International journal of immunopathology and pharmacology

authors： Nappi L,Formisano L,Damiano V,Matano E,Bianco R,Tortora G

更新日期：2010-10-01 00:00:00

abstract：:Involvement of imbalance between pro- and anti-inflammatory events has been reported in the developed pathogenesis after scorpion envenomation. The immunosuppressive and anti-inflammatory properties of tacrolimus (FK-506) have been investigated: i) to better understand evolution of signaling pathways which are involve...

journal_title：International journal of immunopathology and pharmacology

authors： Kabrine M,Laraba-Djebari F

更新日期：2014-01-01 00:00:00

abstract：:Isoprostanes are prostaglandin isomers produced from the peroxidation of polyunsaturated fatty acids from the cellular membrane. They have been used as a specific index of cellular lipoperoxidation and as an indirect measure of oxidative stress. However, these molecules also present several biological activities. An o...

journal_title：International journal of immunopathology and pharmacology

authors： Belli R,Amerio P,Brunetti L,Orlando G,Toto P,Proietto G,Vacca M,Tulli A

更新日期：2005-07-01 00:00:00

abstract：:A decrease in cholesterol blood level, not due to a decrease synthesis by the liver, has been observed in patients suffering from tumors. In this work cholesterol blood was evaluated in patients affected by monoclonal gammopathy who were not subjected to any treatment. The blood of 25 patients were analyzed for protei...

journal_title：International journal of immunopathology and pharmacology

authors： Pugliese L,Bernardini I,Viola-Magni MP,Albi E

更新日期：2006-04-01 00:00:00

abstract：:It is well known that in some conditions bacteria of physiological flora of gastrointestinal tract may become pathogenic. Each complaint which causes injury of gastrointestinal wall integrity permits bacteria to penetrate the tissues and affect the tissue cells. Since mast cells represent one of very important and num...

journal_title：International journal of immunopathology and pharmacology

authors： Brzezińska-Blaszczyk E,Olejnik AK

更新日期：1999-01-01 00:00:00

abstract：:Human coronary artery endothelial cells (HCAEC 5156) were cultured as monolayers and exposed to concentrations of lead (as acetate, Pb) in the culture medium similar or lower than those commonly found in the blood of human beings occupationally or environmentally exposed to this element. Only at the concentration of 2...

journal_title：International journal of immunopathology and pharmacology

authors： Carmignani M,Felaco M,Boscolo P,Di Gioacchino M,Di Giampaolo L,Niu Q,Cesare P,Volpe AR

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Inflammation, which is a hallmark of asthma, is one of the main sources of oxidative stress in the human body. Thiols are powerful antioxidants that protect cells against the consequences of oxidative stress. We aimed to investigate whether asthma and montelukast monotherapy affect the total plasma thiol poo...

journal_title：International journal of immunopathology and pharmacology

authors： Dilek F,Ozkaya E,Kocyigit A,Yazici M,Guler EM,Dundaroz MR

更新日期：2016-03-01 00:00:00

abstract：:Arabinoxylan rice bran (MGN-3/Biobran) is a potent biological response modifier (BRM) that activates natural killer (NK) cells, T cells and monocytes. Currently, little is known regarding the effects of MGN-3 on dendritic cells (DCs), the cell type that bridges innate and adaptive immunity. Therefore, we examined the ...

journal_title：International journal of immunopathology and pharmacology

authors： Ghoneum M,Agrawal S

更新日期：2011-10-01 00:00:00

abstract：:Mast cells are vital mediators of drug allergy and, therefore, studying the relationship between drug allergy and mast cells is essential. Sinomenine is the principal active component of Sinomenium acutum, which has anti-inflammatory and anti-immune effects, and is used to treat various rheumatoid diseases. However, al...

journal_title：International journal of immunopathology and pharmacology

authors： Wang N,Liu R,Liu Y,Zhang R,He L

更新日期：2016-12-01 00:00:00

abstract：:Non-cystic fibrosis bronchiectasis (nCFb) is an acquired condition of variable etiology. An impaired mucociliary clearance seems to be one of the mechanisms behind nCFb, and treatment involves antibiotics, mucoactive agents, and airway clearance techniques (ACTs). Traditional ACTs have four components: postural draina...

journal_title：International journal of immunopathology and pharmacology

authors： Snijders D,Fernandez Dominguez B,Calgaro S,Bertozzi I,Escribano Montaner A,Perilongo G,Barbato A

更新日期：2015-06-01 00:00:00

abstract：:Cyclic AMP phosphodiesterase (cAMP PDE) seems to be important in pulp tissues. High levels of cAMP PDE have been demonstrated to be in dental pulp cells. In the present study cAMP PDE activity was analyzed in normal healthy human dental pulps, in reversible pulpitis and in irreversible pulpitis. Enzymatic cAMP PDE con...

journal_title：International journal of immunopathology and pharmacology

authors： Spoto G,Menna V,Serra E,Santoleri F,Perfetti G,Ciavarelli L,Trentini P

更新日期：2004-09-01 00:00:00

abstract：:We studied the significance of age as a factor affecting prognosis and anti-AChR antibody levels in myasthenia gravis, comparing patients with symptom onset before 50 (37 patients) and at or after 50 (33 patients). More of the older patients, compared to younger ones (69.9% versus 32.4%,p<0. 05) progress...

journal_title：International journal of immunopathology and pharmacology

authors： Kapinas K,Kimiskidis VK,Kazis AD,Kokkas B,Tsolaki M,Georgiadis G

更新日期：1999-09-01 00:00:00

abstract：:In an effort to define the antigenic mechanism that contributes to beneficial therapeutic outcome in patients with polycythemia vera (PV), we screened a human testis cDNA library with serological cloning derived from sera of three PV patients who had undergone therapeutic-induced remission. As a result, we identified ...

journal_title：International journal of immunopathology and pharmacology

authors： Xiong Z,Liu E,Yan Y,Silver RT,Yang F,Chen IH,Hodge I,Verstovsek S,Segura FJ,Wang H,Prchal J,Yang XF

更新日期：2007-04-01 00:00:00

abstract：:We examined the expression of human leukocyte antigen (HLA) and composition of differentiated T cells in the peripheral blood to understand the characteristics of the immune changes in patients with adult-onset Still's disease (AOSD). This study enrolled patients with AOSD (n = 14), patients with rheumatoid arthritis ...

journal_title：International journal of immunopathology and pharmacology

authors： Jung JY,Choi B,Sayeed HM,Suh CH,Kim YW,Kim HA,Sohn S

更新日期：2018-01-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of the Heat Shock Proteins GroES, GroEL and DnaK on the expression of the costimulatory molecules CD80/CD86 in B cells and macrophages. The interactions among these molecules are able to highly influence the immune response through the regulation of cytokine liberation ...

journal_title：International journal of immunopathology and pharmacology

authors： Galdiero M,Pisciotta MG,Gorga F,Petrillo G,Marinelli A,Galdiero E

更新日期：2005-10-01 00:00:00

abstract：:This study aimed to investigate the clinical significance of serum microRNA-219-5p (miR-219-5p) in patients with multiple organ dysfunction syndrome (MODS) caused by acute paraquat (PQ) poisoning, and its correlation with Toll-like Receptor 4 (TLR4). Luciferase reporter assay was used to investigate in vitro the corre...

journal_title：International journal of immunopathology and pharmacology

authors： Dai Y,Liu X,Gao Y

更新日期：2020-01-01 00:00:00

abstract：:About three decades ago, the primary mechanism of action of the non-steroidal anti-inflammatory drugs (NSAIDs) was elucidated when their inhibitory action on the production of prostaglandins was discovered. It was found that their action is centred on the inhibition of the cyclooxygenase (COX) enzyme responsible for c...

journal_title：International journal of immunopathology and pharmacology

authors： van der Bijl P,van der Bijl P Jr

更新日期：2003-05-01 00:00:00

abstract：:To assess the rate of sexual distress, sexual dysfunction and relationship quality and their association with clinical variables in women with systemic sclerosis (SSc), 102 sexually active women with SSc were recruited. Sexual distress, sexual dysfunction and dissatisfaction with relationship quality were investigated...

journal_title：International journal of immunopathology and pharmacology

authors： Rosato E,Rossi C,Molinaro I,Di Giulio MA,Trombetta AC,Marra AM,Gigante A,Barbano B,Quarta S,Pisarri S,Afeltra A,Salsano F

更新日期：2014-04-01 00:00:00

abstract：:In the present study we evaluated B-cell subsets and their functional development in 74 newborns from birth to 6 months of life. Moreover, we evaluated natural antibody production in vitro. The results documented a predominance of naive B-lymphocytes at all time-points evaluated, decreasing from birth to 6 months (p=0...

journal_title：International journal of immunopathology and pharmacology

authors： Avanzini MA,Maccario R,Belloni C,Carrera G,Bertaina A,Cagliuso M,La Rocca M,Valsecchi C,Mantelli M,Castellazzi AM,Quinti I,De Silvestri A,Marconi M

更新日期：2010-01-01 00:00:00

abstract：:The development and growth of the rat heart implies hyperplasia, which stops at birth, and hypertrophy, allowing cardiac mass to grow in response to programmed genetic events along with to haemodynamic overload. Moreover, hypertrophy is accomplished to apoptosis which controls the final number of myocardial cells, del...

journal_title：International journal of immunopathology and pharmacology

authors： Centurione L,Di Giulio C,Santavenere E,Cacchio M,Sabatini N,Rapino C,Bianchi G,Rapino M,Bosco D,Antonucci A,Cataldi A

更新日期：2005-01-01 00:00:00

abstract：:The treatment with infliximab is employed successfully in Crohn's disease (CD) but predictors of efficacy are lacking. Activation of the transcription factor NF-kB has been demonstrated in CD and its inhibition is one of the mechanisms by which anti-inflammatory agents exert their effects. We evaluated the production ...

journal_title：International journal of immunopathology and pharmacology

authors： Guidi L,Costanzo M,Ciarniello M,De Vitis I,Pioli C,Gatta L,Pace L,Tricerri A,Bartoloni C,Coppola L,Balistreri P,Doria G,Fedeli G,Gasbarrini GB

更新日期：2005-01-01 00:00:00

abstract：:Oxidative stress (OS) is well documented in asthma, but so far, little data has been reported in nonasthmatic patients with Seasonal Allergic Rhinitis (SAR). The aim of this study is to investigate the degree of OS and airway inflammation in patients with SAR, with and without concomitant asthma (SAR+A), using breath ...

journal_title：International journal of immunopathology and pharmacology

authors： Gratziou C,Rovina N,Makris M,Simoes DC,Papapetropoulos A,Roussos C

更新日期：2008-10-01 00:00:00

abstract：:Turner's syndrome (TS) is a genetic disorder caused by numeric and/or structural abnormalities of the X chromosome. In a previous study it was observed that acne is less frequent in TS than in the general population. Since the onset of acne in pre-pubertal or pubertal age is related to sebum production, this study eva...

journal_title：International journal of immunopathology and pharmacology

authors： Brazzelli V,Calcaterra V,Muzio F,Klersy C,Larizza D,Borroni G

更新日期：2011-07-01 00:00:00

abstract：:The role of profilin as an allergen has long been questioned. The capacity of profilin to induce respiratory symptoms has recently been demonstrated; moreover, over 50% of patients sensitized to profilin experienced symptoms after the ingestion of plant-derived foods, suggesting that profilin should be considered as a...

journal_title：International journal of immunopathology and pharmacology

authors： Nucera E,Aruanno A,Rizzi A,Pecora V,Patriarca G,Buonomo A,Mezzacappa S,Schiavino D

更新日期：2016-09-01 00:00:00

abstract：:IgG4 have been hypothesized to act as blocking antibodies capable of preventing IgE-mediated effector cell triggering. This study aims to evaluate the changes in IgG4 in children during a period of natural antigen avoidance. Serum IgE and IgG4 were evaluated in a group of asthmatic children, aged between 7 and 17 year...

journal_title：International journal of immunopathology and pharmacology

authors： Piacentini GL,Guerresi S,Kantar A,Lubrano L,Olivieri F,Boner AL,Peroni DG

更新日期：2011-10-01 00:00:00

abstract：:Some studies in animal models showed that several neurotrophins may be implicated in the regulation of light-dependent suprachiasmatic pacemaker and in other functions implicated in long-term memory acquisition during sleep. However, no data are known about the role played by NGF in ultradian regulation in humans. The...

journal_title：International journal of immunopathology and pharmacology

authors： Bersani G,Iannitelli A,Massoni E,Garavini A,Grilli A,Di Giannantonio M,Conti CM,Pancheri P

更新日期：2004-09-01 00:00:00

abstract：:Antibiotic abuse for treating rhinopharyngitis induces the occurrence of resistant bacteria. As topical drugs might reduce this phenomenon, the aims of our study are to evaluate inhaled thiamphenicol associated with acetylcysteine in children with acute bacterial rhinopharyngitis and to compare it with the use of sali...

journal_title：International journal of immunopathology and pharmacology

authors： Varricchio A,Capasso M,Di Gioacchino M,Ciprandi G

更新日期：2008-07-01 00:00:00

abstract：:Type 1 diabetes (T1D) is a heterogeneous disorder characterized by destruction of pancreatic beta cells, culminating in loss of insulin secretion. Data from large epidemiologic studies worldwide indicate that during the last decades the incidence of T1D has increased significantly, reaching percentages of 2-5% annuall...

journal_title：International journal of immunopathology and pharmacology

authors： Piccini B,Toni S,Lenzi L,Guasti M,Barni F,De Martino M

更新日期：2012-04-01 00:00:00

abstract：:The objective of the study is to verify effects of nebulized 3% saline hypertonic solution (HS) in comparison to normal saline (NS) in addition to epinephrine in hospitalized children with bronchiolitis. Infants were randomly assigned either to receive every 6 hours nebulized NS (group I) or 3% HS (group II) in additi...

journal_title：International journal of immunopathology and pharmacology

authors： Miraglia Del Giudice M,Saitta F,Leonardi S,Capasso M,Niglio B,Chinellato I,Decimo F,Maiello N,Capristo C,Perrone L,Peroni D

更新日期：2012-04-01 00:00:00