Efficacy, safety and potential clinical roles of the COX-2-specific inhibitors.

abstract：:Autoantibodies (rheumatoid factor, RF; anti-citrullinated-protein antibodies, ACPA) and complement system are involved in rheumatoid arthritis (RA). ACPA and anti-TNF agents are capable of in vitro modulating complement activity. We investigated the relationships between complement, autoantibodies, and anti-TNF treatm...

journal_title：International journal of immunopathology and pharmacology

authors： Di Muzio G,Perricone C,Ballanti E,Kroegler B,Greco E,Novelli L,Conigliaro P,Cipriani P,Giacomelli R,Perricone R

更新日期：2011-04-01 00:00:00

abstract：:Relapses are frequently observed in subjects with chronic tendinopathies. Corticosteroid injections are usually performed with positive results, but are uncomfortable for the patient and not free from side effects. The aim of this pilot study is to evaluate the short-term efficacy and tolerability of an occlusive Beta...

journal_title：International journal of immunopathology and pharmacology

authors： Salini V,Abate M

更新日期：2011-01-01 00:00:00

abstract：:Antimuscarinic drugs are the first line pharmacotherapy for overactive bladder, but they are not always effective to achieve complete continence. Nevertheless in some patients urodynamic investigations reveal insufficient effects with continuing incontinence events even with dose optimization. The aim of this study is...

journal_title：International journal of immunopathology and pharmacology

authors： Nardulli R,Losavio E,Ranieri M,Fiore P,Megna G,Bellomo RG,Cristella G,Megna M

更新日期：2012-01-01 00:00:00

abstract：:Progressive ageing is associated with an increment of biomolecules modified through oxidation as a result of the action of free radicals deriving from reactive oxygen species that attack biomolecules. During ageing many alterations of renal functions have been reported. Renal ageing is associated with a progressive de...

journal_title：International journal of immunopathology and pharmacology

authors： De Lutiis MA,Felaco M,Gizzi F,Patruno A,Speranza L,Di Giulio C,Conti P,Castellani ML,Petrarca C,Grilli A

更新日期：2004-09-01 00:00:00

abstract：:The aim of this study was to investigate the possible protective effects of diallyl trisulfide (DATS) against naphthalene-induced oxidative and inflammatory damage in the livers and lungs of mice. Elevated serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels showed significant hepatic damag...

journal_title：International journal of immunopathology and pharmacology

authors： Zhang F,Zhang Y,Wang K,Liu G,Yang M,Zhao Z,Li S,Cai J,Cao J

更新日期：2016-06-01 00:00:00

abstract：:The narrow therapeutic index and large inter-individual variability in sirolimus pharmacokinetics (PK) make therapeutic drug monitoring (TDM) necessary. Factors responsible for PK variability are not well understood, and published PK studies do not include pediatric patients with immune cytopenia. The objective of thi...

journal_title：International journal of immunopathology and pharmacology

authors： Cheng X,Zhao Y,Gu H,Zhao L,Zang Y,Wang X,Wu R

更新日期：2020-01-01 00:00:00

abstract：:The present study investigated the sources of discomfort and the symptoms reported by earthquake victims residing in temporary emergency prefabricated accommodation (prefab). The investigation was carried out by means of a questionnaire. 203 prefab occupants and 13 inhabitants of houses, who were chosen as reference p...

journal_title：International journal of immunopathology and pharmacology

authors： Muzi G,Accattoli MP,dell'Omo M,Frillici C,Sapia IE,Abbritti G

更新日期：2004-05-01 00:00:00

abstract：:Mast cells are vital mediators of drug allergy and, therefore, studying the relationship between drug allergy and mast cells is essential. Sinomenine is the principal active component of Sinomenium acutum, which has anti-inflammatory and anti-immune effects, and is used to treat various rheumatoid diseases. However, al...

journal_title：International journal of immunopathology and pharmacology

authors： Wang N,Liu R,Liu Y,Zhang R,He L

更新日期：2016-12-01 00:00:00

abstract：:Paracrine mediators released from endothelial progenitor cells (EPCs) have been implicated in neoangiogenesis following ischemia. Recently, we demonstrated that microvesicles (MVs) derived from EPCs are able to activate an angiogenic program in quiescent endothelial cells by a horizontal transfer of RNA. In this study...

journal_title：International journal of immunopathology and pharmacology

authors： Ranghino A,Cantaluppi V,Grange C,Vitillo L,Fop F,Biancone L,Deregibus MC,Tetta C,Segoloni GP,Camussi G

更新日期：2012-01-01 00:00:00

abstract：:Salmonellosis-induced diarrhea, is one of the commonest cause of childhood mortality in developing countries. Using of probiotics is viewed as a promising means for reducing the pathogenic loads of bacterial infection. The current study aimed to evaluate the potential antimicrobial and immunomodulatory efficacy of iso...

journal_title：International journal of immunopathology and pharmacology

authors： Mazaya B,Hamzawy MA,Khalil MA,Tawkol WM,Sabit H

更新日期：2015-12-01 00:00:00

abstract：:Sublingual immunotherapy with monomeric allergoid (allergoid SLIT), given according to the standard scheme, has proved effective and safe in many clinical trials. However, its build-up phase requires a long time ranging from 16 days to 14 weeks. This study therefore investigated whether, with a four-day up-dosing, the...

journal_title：International journal of immunopathology and pharmacology

authors： D'Anneo RW,Bruno ME,Falagiani P

更新日期：2010-04-01 00:00:00

abstract：:Some studies in animal models showed that several neurotrophins may be implicated in the regulation of light-dependent suprachiasmatic pacemaker and in other functions implicated in long-term memory acquisition during sleep. However, no data are known about the role played by NGF in ultradian regulation in humans. The...

journal_title：International journal of immunopathology and pharmacology

authors： Bersani G,Iannitelli A,Massoni E,Garavini A,Grilli A,Di Giannantonio M,Conti CM,Pancheri P

更新日期：2004-09-01 00:00:00

abstract：:Since the beginning of the 21st century, carbon-based nanomaterials (CNTs) have been introduced in pharmacy and medicine for drug delivery system in therapeutics. CNTs have proved able to transport a wide range of molecules across membranes and into living cells; therefore, they have attracted great interest in biomed...

journal_title：International journal of immunopathology and pharmacology

authors： Lamberti M,Pedata P,Sannolo N,Porto S,De Rosa A,Caraglia M

更新日期：2015-03-01 00:00:00

abstract：:Plague is still endemic in different regions of the world. Current vaccines raise concern for their side effects and limited protection, highlighting the need for an efficacious and rapidly producible vaccine. F1 and V antigens of Yersinia pestis, and F1-V fusion protein produced in Nicotiana benthamiana administered ...

journal_title：International journal of immunopathology and pharmacology

authors： Del Prete G,Santi L,Andrianaivoarimanana V,Amedei A,Domarle O,D' Elios MM,Arntzen CJ,Rahalison L,Mason HS

更新日期：2009-01-01 00:00:00

abstract：:Acrodermatitis enteropathic (AE) is a rare autosomal recessive disorder due to a zinc deficiency and characterized by a classical triad of symptoms: dermatitis, alopecia, and diarrhea. The defective gene is SLC39A4, which encodes a zinc transporter. Nevertheless many abnormalities in SLC39A4 have been relieved, only 5...

journal_title：International journal of immunopathology and pharmacology

authors： Ricci G,Ferrari S,Calamelli E,Ricci L,Neri I,Patrizi A

更新日期：2016-06-01 00:00:00

abstract：:We reported a case of an 11-year-old girl admitted to our hospital for goiter, tachycardia, sweating, and visible and palpable thyroid. Thyroid function tests revealed a low thyrotropin level (<0.004 mIU/L) and elevated free thyroxine level (3.4 ng/ dL) diagnosed with Graves' disease and treated with methimazole. This...

journal_title：International journal of immunopathology and pharmacology

authors： Arrigo T,Cutroneo PM,Vaccaro M,Impollonia D,Squadrito V,Mecchio A,Salpietro C,Altavilla D

更新日期：2016-12-01 00:00:00

abstract：:Silicosis patients suffer from pulmonary fibrosis caused by silica inhalation, as well as autoimmune diseases known as the adjuvant effects of silica. Caplan syndrome complicated with rheumatoid arthritis (RA) is well known epidemiologically, and the incidence of complicated systemic sclerosis (SSc), systemic lupus er...

journal_title：International journal of immunopathology and pharmacology

authors： Otsuki T,Hayashi H,Nishimura Y,Hyodo F,Maeda M,Kumagai N,Miura Y,Kusaka M,Uragami K

更新日期：2011-01-01 00:00:00

abstract：:Non-cystic fibrosis bronchiectasis (nCFb) is an acquired condition of variable etiology. Medical treatment basically involves antibiotics and chest physiotherapy. An impaired mucociliary clearance seems to be one of the mechanisms behind nCFb, and inhaled therapy with mucoactive agents has frequently been used to try ...

journal_title：International journal of immunopathology and pharmacology

authors： Snijders D,Calgaro S,Bertozzi I,Quartesan S,Kozuh I,Lunardi F,Barbato A

更新日期：2013-04-01 00:00:00

abstract：:In an effort to define the antigenic mechanism that contributes to beneficial therapeutic outcome in patients with polycythemia vera (PV), we screened a human testis cDNA library with serological cloning derived from sera of three PV patients who had undergone therapeutic-induced remission. As a result, we identified ...

journal_title：International journal of immunopathology and pharmacology

authors： Xiong Z,Liu E,Yan Y,Silver RT,Yang F,Chen IH,Hodge I,Verstovsek S,Segura FJ,Wang H,Prchal J,Yang XF

更新日期：2007-04-01 00:00:00

abstract：:Mast cells play important role in allergic inflammation by releasing histamine, tryptase and several inflammatory cytokines. Human leukemic mast cells (HMC-1) have been used to study mast cell mediator and their role in inflammatory mechanisms. HMC-1 contain and release several inflammatory mediators, of which the pro...

journal_title：International journal of immunopathology and pharmacology

authors： Alexandrakis MG,Kyriakou DS,Seretakis D,Boucher W,Letourneau R,Kempuraj D,Theoharides TC

更新日期：2003-01-01 00:00:00

abstract：:Interleukin (IL)-8 is a major factor in inflammatory response and the IL-8 levels in exhaled breath condensate (EBC) may be used as a marker of airway inflammation. Airway acidification is implicated in the pathophysiology of obstructive airway diseases and pH EBC values have been used as a marker of airway acidificat...

journal_title：International journal of immunopathology and pharmacology

authors： Bodini A,D'Orazio C,Peroni DG,Corradi M,Zerman L,Folesani G,Assael BM,Boner AL,Piacentini GL

更新日期：2007-07-01 00:00:00

abstract：:Asthma is a chronic airway inflammatory disease associated with airway hyperresponsiveness which affects subjects with genetic predisposition. An association has been reported between some polymorphisms in various cytokine genes and asthma. Most of them are single nucleotide polymorphisms (SNPs). These polymorphisms a...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardolo FL,Sorbello V,Silvestri M,Giacomelli M,Debenedetti VM,Malerba M,Ciprandi G,Rossi GA,Rossi A,Bontempelli M

更新日期：2013-01-01 00:00:00

abstract：:It is well known that in some conditions bacteria of physiological flora of gastrointestinal tract may become pathogenic. Each complaint which causes injury of gastrointestinal wall integrity permits bacteria to penetrate the tissues and affect the tissue cells. Since mast cells represent one of very important and num...

journal_title：International journal of immunopathology and pharmacology

authors： Brzezińska-Blaszczyk E,Olejnik AK

更新日期：1999-01-01 00:00:00

abstract：:The expression of Ikaros family transcription factors and consequently their signalling pathway is limiting for hematopoietic and lymphocyte development in mice and human. Due to their importance, these transcription factors are highly homologous between species. As an initial approach to examining the possible involv...

journal_title：International journal of immunopathology and pharmacology

authors： Paradzik M,Novak S,Mokrovic G,Bordukalo Niksic T,Heckel D,Stipic J,Pavicic Baldani D,Cicin-Sain L,Antica M

更新日期：2012-10-01 00:00:00

abstract：:The aim of this report is to present a new investigative approach to implant dentistry based on the correlation of qualitative and quantitative data reported on the same figure by overlapping different images collected on the specimen with different investigative systems. Six unloaded titanium dental implants retrieve...

journal_title：International journal of immunopathology and pharmacology

authors： Traini T,Degidi M,Murmura G,Piattelli A,Caputi S

更新日期：2007-01-01 00:00:00

abstract：:Since the introduction of the cytological screening programs, a significant reduction in the incidence of cervical cancer has been achieved. Almost all of these cancers are related to high-risk (HR) Human Papillomavirus (HPV) cervical infections. However, the natural history of HPV infection seems to be different in y...

journal_title：International journal of immunopathology and pharmacology

authors： Frega A,Lorenzon L,Giovagnoli MR,De Sanctis L,Fabiano V,Lukic A,Moscarini M,Torrisi MR,French D

更新日期：2011-04-01 00:00:00

abstract：:Varicocele is a common cause of sperm damage. Some studies showed higher concentration of seminal leukocytes in patients with varicocele. The aim of the study was to evaluate seminal leukocyte subpopulations in patients with varicocele. We enrolled 20 patients with varicocele and 20 age-matched healthy men. Sperm anal...

journal_title：International journal of immunopathology and pharmacology

authors： Mongioì LM,Alamo A,Calogero AE,Compagnone M,Giacone F,Cannarella R,La Vignera S,Condorelli RA

更新日期：2020-01-01 00:00:00

abstract：:Allergic drug reactions can be classified as immediate, accelerated or delayed. This classification usually correlates with the mechanism involved: immediate reactions are IgE mediated and delayed reactions are T cell dependent. We analyzed lymphocyte involvement in patients with these reactions by determining cell su...

journal_title：International journal of immunopathology and pharmacology

authors： Torres MJ,Mayorga C,Fernández TD,Cornejo-García JA,Antúnez C,Valenzuela M,Del Prado MF,Rodriguez-Pena R,Blanca M

更新日期：2006-01-01 00:00:00

abstract：:The development and growth of the rat heart implies hyperplasia, which stops at birth, and hypertrophy, allowing cardiac mass to grow in response to programmed genetic events along with to haemodynamic overload. Moreover, hypertrophy is accomplished to apoptosis which controls the final number of myocardial cells, del...

journal_title：International journal of immunopathology and pharmacology

authors： Centurione L,Di Giulio C,Santavenere E,Cacchio M,Sabatini N,Rapino C,Bianchi G,Rapino M,Bosco D,Antonucci A,Cataldi A

更新日期：2005-01-01 00:00:00

abstract：:To assess the rate of sexual distress, sexual dysfunction and relationship quality and their association with clinical variables in women with systemic sclerosis (SSc), 102 sexually active women with SSc were recruited. Sexual distress, sexual dysfunction and dissatisfaction with relationship quality were investigated...

journal_title：International journal of immunopathology and pharmacology

authors： Rosato E,Rossi C,Molinaro I,Di Giulio MA,Trombetta AC,Marra AM,Gigante A,Barbano B,Quarta S,Pisarri S,Afeltra A,Salsano F

更新日期：2014-04-01 00:00:00