Intestinal mucosa-associated bacteria modulate rat mast cell reactivity.

abstract：:It has been shown that lysosomes are involved in B cell apoptosis but lysosomal glycohydrolases have never been investigated during this event. In this study we determined the enzymatic activities of some lysosomal glycohydrolases in human tonsil B lymphocytes (TBL) undergoing in vitro spontaneous apoptosis. Fluorimet...

journal_title：International journal of immunopathology and pharmacology

authors： Rosati E,Mencarelli S,Magini A,Sabatini R,Tassi C,Orlacchio A,Coaccioli S,Frenguelli A,Marconi P,Emiliani C

更新日期：2007-04-01 00:00:00

abstract：:Icatibant, an antagonist of the bradykinin B2 receptor, was approved for the treatment of acute attacks of hereditary angioedema in the EU in 2008. This paper presents the case of a 65-year-old woman affected by frequent acute attacks of hereditary angioedema who benefitted from a change of therapy to icatibant, follo...

journal_title：International journal of immunopathology and pharmacology

authors： Firinu D,Barca MP,Serusi L,Lorrai MM,Peralta MM,Manconi PE,Del Giacco SR

更新日期：2012-01-01 00:00:00

abstract：:There is much evidence to show the efficacy of adalimumab, a human monoclonal antibody targeting tumour necrosis factor-alpha, in the treatment of plaque psoriasis. In this open-label experience, 147 high-need patients suffering from plaque psoriasis, with a mean Psoriasis Area and Severity Index (PASI) of 18.8, and c...

journal_title：International journal of immunopathology and pharmacology

authors： Vena GA,Galluccio A,De Simone C,Mastrandrea V,Buquicchio R,La Greca S,Dattola S,Puglisi Guerra A,Donato L,Cantoresi F,De Pità O,Pezza M,D Agostino M,Vernaci R,Miracapillo A,Valenti G,Cassano N

更新日期：2009-01-01 00:00:00

abstract：:United airway disease (UAD) concept proposed that asthma and rhinitis are both different clinical manifestation of a single inflammatory process. The aim of this study is to assess in upper and lower airways the level of inflammation and oxidative stress and to investigate the relationship between biomarkers in persis...

journal_title：International journal of immunopathology and pharmacology

authors： Profita M,Montuschi P,Bonanno A,Riccobono L,Montalbano AM,Ciabattoni G,Albano GD,Liotta G,Bousquet J,Gjomarkaj M,La Grutta S

更新日期：2010-10-01 00:00:00

abstract：:Multiple sclerosis (MS) is thought to be an autoimmune T-cell-mediated disease directed at myelin antigens of the central nervous system. Besides myelin proteins, lipid components of CNS are supposed to play a role as antigens for T cells in MS. CD1 is a family of MHC-like glycoproteins specialized in capturing and pr...

journal_title：International journal of immunopathology and pharmacology

authors： Caporale CM,Notturno F,Pace M,Aureli A,Di Tommaso V,De Luca G,Farina D,Giovannini A,Uncini A

更新日期：2011-01-01 00:00:00

abstract：:Few studies have evaluated the occurrence of immediate adverse reactions in allergic patients after an ultra-rush regimen of different commercial allergen extracts for sublingual immunotherapy (SLIT) Methods: 679 patients took part in trials of specific ultra-rush SLIT for the treatment of IgE-mediated rhinitis and/or...

journal_title：International journal of immunopathology and pharmacology

authors： Rossi RE,Monasterolo G

更新日期：2005-04-01 00:00:00

abstract：:Exhaled nitric oxide (FeNO) has been associated with bronchial eosinophilia and with airway hyperresponsiveness (AHR) in mild stable asthma. We previously demonstrated in a large project that allergen exposure is able to raise FeNO and to worsen AHR to bradykinin. We postulated that allergen-induced increase in FeN...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardolo FL,Di Stefano A,Silvestri M,Van Schadewijk AM,Malerba M,Hiemstra PS,Sterk PJ

更新日期：2012-01-01 00:00:00

abstract：:Paracrine mediators released from endothelial progenitor cells (EPCs) have been implicated in neoangiogenesis following ischemia. Recently, we demonstrated that microvesicles (MVs) derived from EPCs are able to activate an angiogenic program in quiescent endothelial cells by a horizontal transfer of RNA. In this study...

journal_title：International journal of immunopathology and pharmacology

authors： Ranghino A,Cantaluppi V,Grange C,Vitillo L,Fop F,Biancone L,Deregibus MC,Tetta C,Segoloni GP,Camussi G

更新日期：2012-01-01 00:00:00

abstract：:The narrow therapeutic index and large inter-individual variability in sirolimus pharmacokinetics (PK) make therapeutic drug monitoring (TDM) necessary. Factors responsible for PK variability are not well understood, and published PK studies do not include pediatric patients with immune cytopenia. The objective of thi...

journal_title：International journal of immunopathology and pharmacology

authors： Cheng X,Zhao Y,Gu H,Zhao L,Zang Y,Wang X,Wu R

更新日期：2020-01-01 00:00:00

abstract：:Oxymatrine (OMT) as a type of alkaloids collected from Sophora flavescens Ait exerts some biological functions including anticancer properties. Here, we investigated the therapeutic effects of OMT in gastric cancer cells (HGC 27 and AGS). As a result, the exposure of gastric cancer (GC) cells to OMT contributed to the...

journal_title：International journal of immunopathology and pharmacology

authors： Huang Y,Zhang J,Wang G,Chen X,Zhang R,Liu H,Zhu J

更新日期：2018-01-01 00:00:00

abstract：:Extranodal non-Hodgkin lymphomas limited to the larynx are rare, accounting for less than 1% of all laryngeal neoplasms. The most common site of development of primary laryngeal lymphomas is the supraglottic region. In most cases, the presenting symptoms are hoarseness, dysphagia, dyspnea, and cervical lymphadenopathy...

journal_title：International journal of immunopathology and pharmacology

authors： Zapparoli M,Trolese AR,Remo A,Sina S,Bonetti A,Micheletto C

更新日期：2014-07-01 00:00:00

abstract：:The art of tattooing has increasing in recent decades. Allergic sensitivity to one of the pigments is the most frequent cause of dermatological reactions at the site of the tattoo. Gold is a new pigment used in tattooing, because of its bright yellow color and luster. Allergy to this metal is uncommon. To our knowledg...

journal_title：International journal of immunopathology and pharmacology

authors： Tammaro A,Tuchinda P,Persechino S,Gaspari A

更新日期：2011-10-01 00:00:00

abstract：:To investigate the in vivo role of caspase-3 in Terminal Transferase metabolism DMSO-treated RPMI-8402, a human pre-T cell line was used. In DMSO treated samples (3)H-dGTP incorporation and TdT phosphorylation occurs after 4 hours of treatment. After 8 hours cells undergo TdT proteolysis in addition to its inactivatio...

journal_title：International journal of immunopathology and pharmacology

authors： Trubiani O,Guarnieri S,Paganelli R,Di Primio R

更新日期：2002-09-01 00:00:00

abstract：:Mast cells are vital mediators of drug allergy and, therefore, studying the relationship between drug allergy and mast cells is essential. Sinomenine is the principal active component of Sinomenium acutum, which has anti-inflammatory and anti-immune effects, and is used to treat various rheumatoid diseases. However, al...

journal_title：International journal of immunopathology and pharmacology

authors： Wang N,Liu R,Liu Y,Zhang R,He L

更新日期：2016-12-01 00:00:00

abstract：:Biological and technical failures of implants have already been reported. Mechanical factors are certainly of importance in implant failures, even if their exact nature has not yet been established. The abutment screw fracture or loosening represents a rare, but quite unpleasant failure. The aim of the present researc...

journal_title：International journal of immunopathology and pharmacology

authors： Scarano A,Murmura G,Sinjiari B,Sollazzo V,Spinelli G,Carinci F

更新日期：2011-04-01 00:00:00

abstract：:IgG4 have been hypothesized to act as blocking antibodies capable of preventing IgE-mediated effector cell triggering. This study aims to evaluate the changes in IgG4 in children during a period of natural antigen avoidance. Serum IgE and IgG4 were evaluated in a group of asthmatic children, aged between 7 and 17 year...

journal_title：International journal of immunopathology and pharmacology

authors： Piacentini GL,Guerresi S,Kantar A,Lubrano L,Olivieri F,Boner AL,Peroni DG

更新日期：2011-10-01 00:00:00

abstract：:Asthma is a chronic airway inflammatory disease associated with airway hyperresponsiveness which affects subjects with genetic predisposition. An association has been reported between some polymorphisms in various cytokine genes and asthma. Most of them are single nucleotide polymorphisms (SNPs). These polymorphisms a...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardolo FL,Sorbello V,Silvestri M,Giacomelli M,Debenedetti VM,Malerba M,Ciprandi G,Rossi GA,Rossi A,Bontempelli M

更新日期：2013-01-01 00:00:00

abstract：:Chemokines and their receptors have been implicated in cell migration and metastasis of multiple malignant tumors. But the function of CXCR6 signaling in gastric cancer is not comprehensively understood. In the present study, we hypothesized that CXCR6 signaling might play an essential role in the progression of gastr...

journal_title：International journal of immunopathology and pharmacology

authors： Li Y,Fu LX,Zhu WL,Shi H,Chen LJ,Ye B

更新日期：2015-06-01 00:00:00

abstract：:Solid tumors such as head and neck squamous cell carcinoma (HNSCC) display an intense interaction between tumoral factors and the immune system. Functional modulation of tumor-infiltrating and peripheral blood immune cells plays an important role during tumor progression. In this pilot study we compared biological fun...

journal_title：International journal of immunopathology and pharmacology

authors： Trellakis S,Farjah H,Bruderek K,Dumitru CA,Hoffmann TK,Lang S,Brandau S

更新日期：2011-07-01 00:00:00

abstract：:Hymenoptera stings may be responsible for both local and systemic reactions; these can be immediate or delayed, depending on the time between the sting and the development of signs or symptoms. Delayed clinical reactions have been reported, although unusual, due to serum sickness and/or affecting organs or systems gen...

journal_title：International journal of immunopathology and pharmacology

authors： Ridolo E,Albertini R,Borghi L,Meschi T,Montanari E,Dall'Aglio PP

更新日期：2005-04-01 00:00:00

abstract：:Myrcene (MC), an organic hydrocarbon, was found to exert anti-inflammatory, analgesic, antimutagenic and antioxidant properties. However, the protective role of MC has not been reported against neonatal asthma. Wistar rats induced with asthma were administered with MC; while asthma control and vehicle control were mai...

journal_title：International journal of immunopathology and pharmacology

authors： Du Y,Luan J,Jiang RP,Liu J,Ma Y

更新日期：2020-01-01 00:00:00

abstract：:We report the case of a child with Smith-Lemli-Opitz Syndrome. The pregnancy was complicated by prenatal growth retardation. The baby was admitted to the Neonatal Intensive Care Unit of Chieti when she was five months old. She showed postnatal growth retardation, trouble sucking and swallowing, microcephaly and multip...

journal_title：International journal of immunopathology and pharmacology

authors： Domizio S,Pallotta R,Romanelli A,Puglielli C,Pollice R,Casacchia M,Conte E,Domizio R,Sabatino G

更新日期：2006-04-01 00:00:00

abstract：:The aim of this study is to investigate the expression of the chromosomal passenger protein Aurora B and its activated (phosphorylated) form in a large series of human oral squamous cell cancers (OSCC) and to evaluate its clinical and prognostic significance. Western blotting analysis revealed overexpression of both A...

journal_title：International journal of immunopathology and pharmacology

authors： Pannone G,Hindi SA,Santoro A,Sanguedolce F,Rubini C,Cincione RI,De Maria S,Tortorella S,Rocchetti R,Cagiano S,Pedicillo C,Serpico R,Lo Muzio L,Bufo P

更新日期：2011-01-01 00:00:00

abstract：:Involvement of imbalance between pro- and anti-inflammatory events has been reported in the developed pathogenesis after scorpion envenomation. The immunosuppressive and anti-inflammatory properties of tacrolimus (FK-506) have been investigated: i) to better understand evolution of signaling pathways which are involve...

journal_title：International journal of immunopathology and pharmacology

authors： Kabrine M,Laraba-Djebari F

更新日期：2014-01-01 00:00:00

abstract：:In the present study we evaluated B-cell subsets and their functional development in 74 newborns from birth to 6 months of life. Moreover, we evaluated natural antibody production in vitro. The results documented a predominance of naive B-lymphocytes at all time-points evaluated, decreasing from birth to 6 months (p=0...

journal_title：International journal of immunopathology and pharmacology

authors： Avanzini MA,Maccario R,Belloni C,Carrera G,Bertaina A,Cagliuso M,La Rocca M,Valsecchi C,Mantelli M,Castellazzi AM,Quinti I,De Silvestri A,Marconi M

更新日期：2010-01-01 00:00:00

abstract：:About three decades ago, the primary mechanism of action of the non-steroidal anti-inflammatory drugs (NSAIDs) was elucidated when their inhibitory action on the production of prostaglandins was discovered. It was found that their action is centred on the inhibition of the cyclooxygenase (COX) enzyme responsible for c...

journal_title：International journal of immunopathology and pharmacology

authors： van der Bijl P,van der Bijl P Jr

更新日期：2003-05-01 00:00:00

abstract：:We describe the case of a 30-year-old female with no family history of psoriasis and suffering from Crohn's disease successfully treated with infliximab at the dosage of 5 mg/kg. On the 15th week from the start of therapy, the patient developed a palmoplantar pustular psoriasis, which spread to the arms, trunk and sca...

journal_title：International journal of immunopathology and pharmacology

authors： Manni E,Barachini P

更新日期：2009-07-01 00:00:00

abstract：:Acosta YY, Montes-Casado M, Aragoneses L et al. (2014) Suppression of CD4(+) T lymphocyte activation "in vitro" and experimental encephalomyelitis "in vivo" by the phosphatidyl inositol 3-kinase inhibitor PIK-75. International Journal of Immunopathology and Pharmacology 27(1): 53-67. In the Acknowledgements section of...

journal_title：International journal of immunopathology and pharmacology

authors：

更新日期：2015-03-01 00:00:00

abstract：:HSP60 has been implicated in chronic inflammatory disease pathogenesis, including chronic obstructive pulmonary disease (COPD), but the mechanisms by which this chaperonin would act are poorly understood. A number of studies suggest a role for extracellular HSP60, since it can be secreted from cells and bind Toll-like...

journal_title：International journal of immunopathology and pharmacology

authors： Sangiorgi C,Vallese D,Gnemmi I,Bucchieri F,Balbi B,Brun P,Leone A,Giordano A,Conway de Macario E,Macario AJ,Cappello F,Di Stefano A

更新日期：2017-12-01 00:00:00

abstract：:This study aimed to investigate the effects of a novel patented Mg-3Nd-0.2Zn-0.4Zr (weight %, JDBM) alloy on osteoblastic cell function, as these cells play an important role in bone repair and remodeling. The associated effects of the JDBM alloy on osteoblastic cell function involving cell adhesion, cell proliferatio...

journal_title：International journal of immunopathology and pharmacology

authors： Wang Y,Ouyang Y,Pang X,Mao L,Yuan G,Jiang Y,He Y

更新日期：2012-07-01 00:00:00