Acute polyradiculoneuropathy occurring after hymenoptera stings: a clinical case study.

Abstract:

:Hymenoptera stings may be responsible for both local and systemic reactions; these can be immediate or delayed, depending on the time between the sting and the development of signs or symptoms. Delayed clinical reactions have been reported, although unusual, due to serum sickness and/or affecting organs or systems generally not involved in the immediate reaction, such as heart, kidneys, central and peripheral nervous systems. This paper describes the clinical and immunological findings in a 51-year-old subject, who, after two stings of paper wasps, the second one after the third venom immunotherapy (VIT) injection, presented immediate large local and systemic allergic reactions which quickly improved after e.v. methylprednisolone administration. About 40 hours later, he developed acute polyradiculoneuropathy with muscle weakness, paresthesia, difficulties in standing up and walking. Skin tests and specific IgE determination showed allergy to paper wasp. The activation, by wasp venom, of peripheral blood mononuclear cells in primary culture, evaluated by tritiated thymidine incorporation proliferation assay, showed an important hypersensitivity to wasp venom. Therefore our results suggest the hypothesis that the polyradiculoneuritis causative etiopathogenetic mechanism might be a delayed immunological response to wasp antigens followed by an allergy-triggered autoimmune reaction, as previously suggested by other authors; they found lymphocytic infiltrates in demyelinization areas and at perivascular levels, by histologic examination of autoptical and bioptical material of patients with nervous system lesions after hymenoptera stings.

authors

Ridolo E,Albertini R,Borghi L,Meschi T,Montanari E,Dall'Aglio PP

doi

10.1177/039463200501800220

keywords:

subject

Has Abstract

pub_date

2005-04-01 00:00:00

pages

385-90

issue

2

eissn

0394-6320

issn

2058-7384

pii

20

journal_volume

18

pub_type

杂志文章
  • Usefulness of Atopy Patch Test on a child with milk protein-induced enterocolitis syndrome: a case report.

    abstract::We describe the case of a child affected by milk-protein induced enterocolitis, in which oral challenge with corn was performed without symptoms after a negative specific Atopy Patch Test. Food protein-induced enterocolitis syndrome (FPIES) is an uncommon nonIgE-mediated gastrointestinal food hypersensitivity of infan...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 信件

    doi:10.1177/039463201302600327

    authors: Scaparrotta A,Di Pillo S,Consilvio NP,Attanasi M,Cingolani A,Rapino D,Cerasa M,Pucci N,Di Gioacchino M,Chiarelli F

    更新日期:2013-07-01 00:00:00

  • Peripheral blood neutrophil granulocytes from patients with head and neck squamous cell carcinoma functionally differ from their counterparts in healthy donors.

    abstract::Solid tumors such as head and neck squamous cell carcinoma (HNSCC) display an intense interaction between tumoral factors and the immune system. Functional modulation of tumor-infiltrating and peripheral blood immune cells plays an important role during tumor progression. In this pilot study we compared biological fun...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201102400314

    authors: Trellakis S,Farjah H,Bruderek K,Dumitru CA,Hoffmann TK,Lang S,Brandau S

    更新日期:2011-07-01 00:00:00

  • Dual effect of methylprednsolone pulses on apoptosis of peripheral leukocytes in patients with renal diseases.

    abstract::It is well known that change in apoptosis may modulate the natural story of illness, and that many drugs may act through modulation of apoptosis, but the role of steroids in acting through apoptosis in different settings, including renal diseases, has still to be elucidated. We studied the in vivo effects of steroids ...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200601900321

    authors: Stratta P,Canavese C,Fenoglio R,Priolo G,Grillo A,Aimo G,Quaglia M,Pagni R

    更新日期:2006-07-01 00:00:00

  • Safety and efficacy of etanercept in children with juvenile-onset Behcets disease.

    abstract::Behcets disease (BD) is a chronic, relapsing, multi-system inflammatory disorder, clinically characterized by recurrent oral and genital ulcers, skin lesions, and uveitis. Other manifestations include arthritis, a positive pathergy test, thrombophlebitis, central nervous system disease and gastrointestinal ulcerations...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 信件

    doi:10.1177/039463200902200235

    authors: Cantarini L,Tinazzi I,Caramaschi P,Bellisai F,Brogna A,Galeazzi M

    更新日期:2009-04-01 00:00:00

  • Prognostic implication of high risk human papillomavirus E6 and E7 mRNA in patients with intraepithelial lesions of the cervix in relationship to age.

    abstract::Since the introduction of the cytological screening programs, a significant reduction in the incidence of cervical cancer has been achieved. Almost all of these cancers are related to high-risk (HR) Human Papillomavirus (HPV) cervical infections. However, the natural history of HPV infection seems to be different in y...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201102400219

    authors: Frega A,Lorenzon L,Giovagnoli MR,De Sanctis L,Fabiano V,Lukic A,Moscarini M,Torrisi MR,French D

    更新日期:2011-04-01 00:00:00

  • Elevated 8-isoprostane levels in basal cell carcinoma and in UVA irradiated skin.

    abstract::Isoprostanes are prostaglandin isomers produced from the peroxidation of polyunsaturated fatty acids from the cellular membrane. They have been used as a specific index of cellular lipoperoxidation and as an indirect measure of oxidative stress. However, these molecules also present several biological activities. An o...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200501800309

    authors: Belli R,Amerio P,Brunetti L,Orlando G,Toto P,Proietto G,Vacca M,Tulli A

    更新日期:2005-07-01 00:00:00

  • Effects of zafirlukast on capsular contracture: controlled study measuring the mammary compliance.

    abstract::Capsular contracture is a highly distressing, difficult complication after breast augmentation for both the patient and the surgeon. Although capsular contracture is a multifactorial process, one common denominator in the successful treatment of this complication is believed to be the abatement of inflammation. Leukot...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/039463200702000315

    authors: Scuderi N,Mazzocchi M,Rubino C

    更新日期:2007-07-01 00:00:00

  • Aberrant miR-219-5p is correlated with TLR4 and serves as a novel biomarker in patients with multiple organ dysfunction syndrome caused by acute paraquat poisoning.

    abstract::This study aimed to investigate the clinical significance of serum microRNA-219-5p (miR-219-5p) in patients with multiple organ dysfunction syndrome (MODS) caused by acute paraquat (PQ) poisoning, and its correlation with Toll-like Receptor 4 (TLR4). Luciferase reporter assay was used to investigate in vitro the corre...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/2058738420974888

    authors: Dai Y,Liu X,Gao Y

    更新日期:2020-01-01 00:00:00

  • High serum levels of CXC (CXCL10) and CC (CCL2) chemokines in untreated essential hypertension.

    abstract::Hypertension has been suggested to exert pro-inflammatory actions through increased expression of several mediators, including chemokines. Chemokines are involved in inflammatory and autoimmune disorders, and in the formation of atherosclerotic lesions through promotion of inflammatory cell migration. The aim of this ...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201202500208

    authors: Antonelli A,Fallahi P,Ferrari SM,Ghiadoni L,Virdis A,Mancusi C,Centanni M,Taddei S,Ferrannini E

    更新日期:2012-04-01 00:00:00

  • Cyclic Amp phosphodiesterase activity in normal and inflamed human dental pulp.

    abstract::Cyclic AMP phosphodiesterase (cAMP PDE) seems to be important in pulp tissues. High levels of cAMP PDE have been demonstrated to be in dental pulp cells. In the present study cAMP PDE activity was analyzed in normal healthy human dental pulps, in reversible pulpitis and in irreversible pulpitis. Enzymatic cAMP PDE con...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:

    authors: Spoto G,Menna V,Serra E,Santoleri F,Perfetti G,Ciavarelli L,Trentini P

    更新日期:2004-09-01 00:00:00

  • Impact of mast cells on the skin.

    abstract::When through the skin a foreign antigen enters it provokes an immune response and inflammatory reaction. Mast cells are located around small vessels that are involved in vasaldilation. They mature under the influence of local tissue to various cytokines. Human skin mast cells play an essential role in diverse physiolo...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 社论,评审

    doi:10.1177/039463201302600403

    authors: Kritas SK,Saggini A,Varvara G,Murmura G,Caraffa A,Antinolfi P,Toniato E,Pantalone A,Neri G,Frydas S,Rosati M,Tei M,Speziali A,Saggini R,Pandolfi F,Cerulli G,Theoharides TC,Conti P

    更新日期:2013-10-01 00:00:00

  • The immunosuppressor st1959, a 3,5-diaryl-s-triazole derivative, inhibits T cell activation by reducing NFAT nuclear residency.

    abstract::3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole (ST1959) has shown therapeutic effects in several animal models of autoimmune diseases. In this study the effects of ST1959 were further investigated in a murine model of colitis. The evidence obtained indicates that the beneficial effects exerted by ST1959 rely ...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200902200105

    authors: Lindstedt R,Ruggiero V,D' Alessio V,Manganello S,Petronzelli F,Stasi MA,Vendetti S,Assandri A,Carminati P,De Santis R

    更新日期:2009-01-01 00:00:00

  • Immunomodulatory and antimicrobial efficacy of Lactobacilli against enteropathogenic infection of Salmonella typhi: In-vitro and in-vivo study.

    abstract::Salmonellosis-induced diarrhea, is one of the commonest cause of childhood mortality in developing countries. Using of probiotics is viewed as a promising means for reducing the pathogenic loads of bacterial infection. The current study aimed to evaluate the potential antimicrobial and immunomodulatory efficacy of iso...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/0394632015592099

    authors: Mazaya B,Hamzawy MA,Khalil MA,Tawkol WM,Sabit H

    更新日期:2015-12-01 00:00:00

  • Functional anatomy of the Eustachian tube.

    abstract::The Eustachian tube (ET) is divided in 3 portions: a bony portion, a cartilaginous portion, and a junctional portion. From an anatomical-functional point of view, the bony portion of ET is the region of ventilation and clearance of secretions, and is lined by pseudostratified, ciliated, columnar epithelium, with an an...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章,评审

    doi:

    authors: Cunsolo E,Marchioni D,Leo G,Incorvaia C,Presutti L

    更新日期:2010-01-01 00:00:00

  • Topical cyclosporin in the treatment of dermatologic diseases.

    abstract::Cyclosporine A (CsA) has been in clinical use for some decades, primarily for the prevention and treatment of organ transplant rejection and graft-versus-host disease. In more recent years, Cyclosporine has been recognized as beneficial in the treatment of dermatologic diseases, such as: psoriasis, lichen planus, Behc...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200201500203

    authors: Feliciani C,Tulli A

    更新日期:2002-05-01 00:00:00

  • Sulphurous thermal water increases the release of the anti-inflammatory cytokine IL-10 and modulates antioxidant enzyme activity.

    abstract::The beneficial effects of hot springs have been known for centuries and treatments with sulphurous thermal waters are recommended in a number of chronic pathologies as well as acute recurrent infections. However, the positive effects of the therapy are often evaluated in terms of subjective sense of wellbeing and symp...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201302600307

    authors: Prandelli C,Parola C,Buizza L,Delbarba A,Marziano M,Salvi V,Zacchi V,Memo M,Sozzani S,Calza S,Uberti D,Bosisio D

    更新日期:2013-07-01 00:00:00

  • Perioperative period: immunological modifications.

    abstract::Surgical stress induces complex modifications in the hemodynamic, metabolic, neuro-hormonal and immune response of the individual. The magnitude of these alterations depends on preoperative events leading to surgery, the severity of surgical trauma, and also on post-operative/post-traumatic complications (multiple hit...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章,评审

    doi:10.1177/03946320110240s302

    authors: Cardinale F,Chinellato I,Caimmi S,Peroni DG,Franceschini F,Miraglia Del Giudice M,Bernardini R

    更新日期:2011-07-01 00:00:00

  • Surgical debridement plus topical cyclosporine A in the treatment of vernal shield ulcers.

    abstract::Vernal keratoconjunctivitis (VKC) is a severe chronic bilateral inflammation of the ocular surface characterized by seasonal exacerbations. Long-term prognosis is generally good; however, 6% develop sequelae responsible for permanent visual impairment. Corneal involvement is almost always present, consisting of puncta...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201202500326

    authors: Caputo R,Pucci N,Mori F,De Libero C,Di Grande L,Bacci GM

    更新日期:2012-07-01 00:00:00

  • Plasma total thiol pool in children with asthma: Modulation during montelukast monotherapy.

    abstract:BACKGROUND:Inflammation, which is a hallmark of asthma, is one of the main sources of oxidative stress in the human body. Thiols are powerful antioxidants that protect cells against the consequences of oxidative stress. We aimed to investigate whether asthma and montelukast monotherapy affect the total plasma thiol poo...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/0394632015621563

    authors: Dilek F,Ozkaya E,Kocyigit A,Yazici M,Guler EM,Dundaroz MR

    更新日期:2016-03-01 00:00:00

  • Role of nasal cytology.

    abstract::Nasal cytology represents a valid method in the differential diagnosis of allergic and non-allergic nasal diseases, as it is simple, safe, non-invasive, cost-effective, and easy to perform both in the medical and paediatric office. In particular, through cytological investigation it is possible to diagnose a group of ...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章,评审

    doi:

    authors: Gelardi M,Fiorella ML,Russo C,Fiorella R,Ciprandi G

    更新日期:2010-01-01 00:00:00

  • Evaluation of seminal fluid leukocyte subpopulations in patients with varicocele.

    abstract::Varicocele is a common cause of sperm damage. Some studies showed higher concentration of seminal leukocytes in patients with varicocele. The aim of the study was to evaluate seminal leukocyte subpopulations in patients with varicocele. We enrolled 20 patients with varicocele and 20 age-matched healthy men. Sperm anal...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 信件

    doi:10.1177/2058738420925719

    authors: Mongioì LM,Alamo A,Calogero AE,Compagnone M,Giacone F,Cannarella R,La Vignera S,Condorelli RA

    更新日期:2020-01-01 00:00:00

  • Phloretin alleviates dinitrochlorobenzene-induced dermatitis in BALB/c mice.

    abstract::Atopic dermatitis (AD) is a chronic inflammatory disease of the skin that substantially affects a patient's quality of life. While steroids are the most common therapy used to temporally alleviate the symptoms of AD, effective and nontoxic alternatives are urgently needed. In this study, we utilized a natural, plant-d...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/2058738420929442

    authors: Wu CS,Lin SC,Li S,Chiang YC,Bracci N,Lehman CW,Tang KT,Lin CC

    更新日期:2020-01-01 00:00:00

  • Myasthenia gravis: correlation of age with clinical course and anti-AChr antibody levels.

    abstract::We studied the significance of age as a factor affecting prognosis and anti-AChR antibody levels in myasthenia gravis, comparing patients with symptom onset before 50 (37 patients) and at or after 50 (33 patients). More of the older patients, compared to younger ones (69.9% versus 32.4%,p<0. 05) progress...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:

    authors: Kapinas K,Kimiskidis VK,Kazis AD,Kokkas B,Tsolaki M,Georgiadis G

    更新日期:1999-09-01 00:00:00

  • Paraneoplastic sensitive neuropathy associated with anti-hu antibodies in a neuroendocrine tumor of duodenum: a case report.

    abstract::Paraneoplastic sensitive neuropathy is one of the most common presentations among a group of cancer-related disorders known as Paraneoplastic Neurological Syndromes (PNS). PNS likely have an autoimmune etiology since they have been associated with the presence of antibodies against neuronal antigens expressed by tumor...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 信件

    doi:10.1177/039463201002300435

    authors: Nappi L,Formisano L,Damiano V,Matano E,Bianco R,Tortora G

    更新日期:2010-10-01 00:00:00

  • Blockade of CXCR6 reduces invasive potential of gastric cancer cells through inhibition of AKT signaling.

    abstract::Chemokines and their receptors have been implicated in cell migration and metastasis of multiple malignant tumors. But the function of CXCR6 signaling in gastric cancer is not comprehensively understood. In the present study, we hypothesized that CXCR6 signaling might play an essential role in the progression of gastr...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/0394632015584502

    authors: Li Y,Fu LX,Zhu WL,Shi H,Chen LJ,Ye B

    更新日期:2015-06-01 00:00:00

  • Increased expression of CCL4/MIP-1β in CD8+ cells and CD4+ cells in sarcoidosis.

    abstract::Sarcoidosis is a granulomatous disease with an increased accumulation of T cells in lungs as a result of on-site proliferation and chemotaxis induced by chemokines. It has already been demonstrated that CCL3-5 levels were increased in BAL fluid of sarcoidosis patients. To analyze the expression of CCL3-5 chemokines by...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201402700205

    authors: Barczyk A,Pierzchała E,Caramori G,Sozańska E

    更新日期:2014-04-01 00:00:00

  • Carbon nanotubes: Properties, biomedical applications, advantages and risks in patients and occupationally-exposed workers.

    abstract::Since the beginning of the 21st century, carbon-based nanomaterials (CNTs) have been introduced in pharmacy and medicine for drug delivery system in therapeutics. CNTs have proved able to transport a wide range of molecules across membranes and into living cells; therefore, they have attracted great interest in biomed...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 社论,评审

    doi:10.1177/0394632015572559

    authors: Lamberti M,Pedata P,Sannolo N,Porto S,De Rosa A,Caraglia M

    更新日期:2015-03-01 00:00:00

  • Complement system and rheumatoid arthritis: relationships with autoantibodies, serological, clinical features, and anti-TNF treatment.

    abstract::Autoantibodies (rheumatoid factor, RF; anti-citrullinated-protein antibodies, ACPA) and complement system are involved in rheumatoid arthritis (RA). ACPA and anti-TNF agents are capable of in vitro modulating complement activity. We investigated the relationships between complement, autoantibodies, and anti-TNF treatm...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201102400209

    authors: Di Muzio G,Perricone C,Ballanti E,Kroegler B,Greco E,Novelli L,Conigliaro P,Cipriani P,Giacomelli R,Perricone R

    更新日期:2011-04-01 00:00:00

  • Electrochemical behaviour of titanium in ammine and stannous fluoride and chlorhexidine 0.2 percent mouthwashes.

    abstract::Titanium (Ti) is widely used in dentistry. Fluorides at acid pH could destabilize Ti oxide and make it susceptible to corrosion. The behaviour of IV grade machined Ti disks in 5 electrolytic solutions: Fusayama artificial saliva (Fas), ammine fluoride-stannous fluoride (Am-SnF2), 0.2 percent Chlorexidine (CHX) 0.20 pe...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201002300132

    authors: Quaranta A,Ronconi LF,Di Carlo F,Vozza I,Quaranta M

    更新日期:2010-01-01 00:00:00

  • Psoriasis induced by infliximab in a patient suffering from Crohn's disease.

    abstract::We describe the case of a 30-year-old female with no family history of psoriasis and suffering from Crohn's disease successfully treated with infliximab at the dosage of 5 mg/kg. On the 15th week from the start of therapy, the patient developed a palmoplantar pustular psoriasis, which spread to the arms, trunk and sca...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 信件

    doi:10.1177/039463200902200331

    authors: Manni E,Barachini P

    更新日期:2009-07-01 00:00:00