Abstract:
:We describe the case of a child affected by milk-protein induced enterocolitis, in which oral challenge with corn was performed without symptoms after a negative specific Atopy Patch Test. Food protein-induced enterocolitis syndrome (FPIES) is an uncommon nonIgE-mediated gastrointestinal food hypersensitivity of infancy, characterized by severe vomiting and diarrhea arising within 1 to 3 hours after ingestion of the causative food. Little is known about the pathophysiology of FPIES. The absence of food-specific IgE as demonstrated by negative skin prick tests suggests that the disease is not caused by an early onset IgE-mediated reaction. Atopy Patch Test has been described as sensitive and predictive in this syndrome. The hypothesis on the immunological pathogenesis has been discussed on the basis of literature data.
journal_name
Int J Immunopathol Pharmacolauthors
Scaparrotta A,Di Pillo S,Consilvio NP,Attanasi M,Cingolani A,Rapino D,Cerasa M,Pucci N,Di Gioacchino M,Chiarelli Fdoi
10.1177/039463201302600327subject
Has Abstractpub_date
2013-07-01 00:00:00pages
795-800issue
3eissn
0394-6320issn
2058-7384pii
27journal_volume
26pub_type
信件abstract::Occupational exposure to chromium may cause airway inflammation and bronchial asthma. In this study we investigated the effect of chromium on the respiratory tract of exposed and non-exposed electroplating workers using spirometry and analysis of induced sputum (IS), exhaled breath condensate (EBC) and nasal lavage fl...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:
更新日期:2006-10-01 00:00:00
abstract::When through the skin a foreign antigen enters it provokes an immune response and inflammatory reaction. Mast cells are located around small vessels that are involved in vasaldilation. They mature under the influence of local tissue to various cytokines. Human skin mast cells play an essential role in diverse physiolo...
journal_title:International journal of immunopathology and pharmacology
pub_type: 社论,评审
doi:10.1177/039463201302600403
更新日期:2013-10-01 00:00:00
abstract::Immunosuppressive treatment has changed the prognosis of Lupus nephritis over time, but improvement in prognosis is difficult to analyze in different historical periods, and should be better demonstrated in comparison with life expectancy of sex-and age-matched people. Long-term patient and renal survival of 90 patien...
journal_title:International journal of immunopathology and pharmacology
pub_type: 信件
doi:10.1177/039463200902200432
更新日期:2009-10-01 00:00:00
abstract::Myrcene (MC), an organic hydrocarbon, was found to exert anti-inflammatory, analgesic, antimutagenic and antioxidant properties. However, the protective role of MC has not been reported against neonatal asthma. Wistar rats induced with asthma were administered with MC; while asthma control and vehicle control were mai...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/2058738420954948
更新日期:2020-01-01 00:00:00
abstract::Involvement of imbalance between pro- and anti-inflammatory events has been reported in the developed pathogenesis after scorpion envenomation. The immunosuppressive and anti-inflammatory properties of tacrolimus (FK-506) have been investigated: i) to better understand evolution of signaling pathways which are involve...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463201402700109
更新日期:2014-01-01 00:00:00
abstract::Acrodermatitis enteropathic (AE) is a rare autosomal recessive disorder due to a zinc deficiency and characterized by a classical triad of symptoms: dermatitis, alopecia, and diarrhea. The defective gene is SLC39A4, which encodes a zinc transporter. Nevertheless many abnormalities in SLC39A4 have been relieved, only 5...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/0394632015606845
更新日期:2016-06-01 00:00:00
abstract::In an effort to define the antigenic mechanism that contributes to beneficial therapeutic outcome in patients with polycythemia vera (PV), we screened a human testis cDNA library with serological cloning derived from sera of three PV patients who had undergone therapeutic-induced remission. As a result, we identified ...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463200702000218
更新日期:2007-04-01 00:00:00
abstract::Mast cells play important role in allergic inflammation by releasing histamine, tryptase and several inflammatory cytokines. Human leukemic mast cells (HMC-1) have been used to study mast cell mediator and their role in inflammatory mechanisms. HMC-1 contain and release several inflammatory mediators, of which the pro...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463200301600106
更新日期:2003-01-01 00:00:00
abstract::Specific immunotherapy (SIT) is the only treatment able to not only act on the symptoms of allergy but also act on the causes. At present, SIT may be administered in two forms: subcutaneous (SCIT) and sublingual immunotherapy (SLIT). SCIT represents the standard modality of treatment while SLIT has recently been intro...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章,评审
doi:10.1177/03946320110240S413
更新日期:2011-10-01 00:00:00
abstract::Sublingual immunotherapy with monomeric allergoid (allergoid SLIT), given according to the standard scheme, has proved effective and safe in many clinical trials. However, its build-up phase requires a long time ranging from 16 days to 14 weeks. This study therefore investigated whether, with a four-day up-dosing, the...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1177/039463201002300217
更新日期:2010-04-01 00:00:00
abstract::This study aimed to explore the role and mechanism(s) of flunarizine hydrochloride in the intracerebral hemorrhage (ICH) rats. The 32 adult male Sprague Dawley (SD) rats were randomly assigned into four groups: control group, sham group, ICH group, and FLU + ICH group. The effects of flunarizine hydrochloride were ass...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/0394632017742224
更新日期:2017-12-01 00:00:00
abstract::Few studies have evaluated the occurrence of immediate adverse reactions in allergic patients after an ultra-rush regimen of different commercial allergen extracts for sublingual immunotherapy (SLIT) Methods: 679 patients took part in trials of specific ultra-rush SLIT for the treatment of IgE-mediated rhinitis and/or...
journal_title:International journal of immunopathology and pharmacology
pub_type: 临床试验,杂志文章
doi:10.1177/039463200501800210
更新日期:2005-04-01 00:00:00
abstract::In order to understand the immunogenicity of a tumor-associated antigen (TAA), Ras family small GTP binding protein (Ra1A) in hepatocellular carcinoma (HCC), autoantibody responses to RalA were evaluated by enzyme-linked immunosorbent assay (ELISA), Western blotting and indirect immunofluorescence assay in sera from p...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463200902200319
更新日期:2009-07-01 00:00:00
abstract::The incidence of asthma is increasing worldwide, but morbidity and mortality are decreasing, because of improvements in medical care. Although the incidence of severe perioperative bronchospasm is relatively low in asthmatics undergoing anaesthesia, when it does occur it may be life-threatening. Preoperative assessmen...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章,评审
doi:10.1177/03946320110240s312
更新日期:2011-07-01 00:00:00
abstract::This study aims to characterize phenotypic and genotypic virulence traits in Escherichia coli strains, isolated from outpatients with urinary tract infections, comparing with those obtained from inpatients. Information on the pathogenic behavior of the uropathogenic strains was obtained by monitoring different biologi...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463200802100326
更新日期:2008-07-01 00:00:00
abstract::Ticks are obligate hematophagous arthropods that are parasites in every class of vertebrates in most regions of the world. They are also considered to be important vectors for the transmission of human infectious diseases. In the present study we used polymer chain reaction (PCR) amplification analysis to determine th...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463200301600203
更新日期:2003-05-01 00:00:00
abstract::Many oncogenis and tumour suppressor genes found inside normal and pathological cells are fundamental for the processes of development, proliferation and tissue differentiation. The purpose of our study is to show the presence and a possible relationship of the VEGF protein during different phases of the development o...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463200501800319
更新日期:2005-07-01 00:00:00
abstract::The use of particles from micro to nanoscale provides benefits to diverse scientific fields, but because a large percentage of their atoms lie on the surface, nanomaterials could be highly reactive and pose potential risks to humans. Due to their wide range of application, Cobalt nano-particles are of great interest b...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:
更新日期:2006-10-01 00:00:00
abstract::The aims of the present study were: (i) to assess whether H. pylori could be successfully detected by PCR from the same biopsy sample used for CPtest; and ii) to evaluate CPtest comparatively to both PCR and histology for detection of H. pylori infection in dyspeptic patients. Three antral gastric biopsies were collec...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463200401700111
更新日期:2004-01-01 00:00:00
abstract::Classification of upper tract urothelial preneoplastic and neoplastic lesions mirrors that of the urinary bladder, with all lesions of the bladder urothelium being possible in the upper tract and vice versa. There are three major groups of non-invasive urothelial neoplasms: flat, papillary, and inverted. These three g...
journal_title:International journal of immunopathology and pharmacology
pub_type: 社论,评审
doi:10.1177/039463201402700406
更新日期:2014-10-01 00:00:00
abstract:INTRODUCTION:Indoleamine 2,3-dioxygenase (IDO) was a potential tumor immunotherapy target. IDO inhibitors showed inconsistent results in clinical trials, but no preclinical comparative study was reported. The purpose of this study was to evaluate the differences of representative IDO inhibitors (PCC0208009, INCB024360,...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/2058738420950584
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Inflammation, which is a hallmark of asthma, is one of the main sources of oxidative stress in the human body. Thiols are powerful antioxidants that protect cells against the consequences of oxidative stress. We aimed to investigate whether asthma and montelukast monotherapy affect the total plasma thiol poo...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/0394632015621563
更新日期:2016-03-01 00:00:00
abstract::The present study investigated the sources of discomfort and the symptoms reported by earthquake victims residing in temporary emergency prefabricated accommodation (prefab). The investigation was carried out by means of a questionnaire. 203 prefab occupants and 13 inhabitants of houses, who were chosen as reference p...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/03946320040170S217
更新日期:2004-05-01 00:00:00
abstract::The beneficial effects of hot springs have been known for centuries and treatments with sulphurous thermal waters are recommended in a number of chronic pathologies as well as acute recurrent infections. However, the positive effects of the therapy are often evaluated in terms of subjective sense of wellbeing and symp...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463201302600307
更新日期:2013-07-01 00:00:00
abstract::Pseudoxanthoma Elasticum-like Papillary Dermal Elastolysis (PXE-PDE) is a peculiar idiopathic elastolytic disorder that clinically resembles Psudoxanthoma elasticum(PXE). It is histologically characterized by a total or partial loss of elastic fibers in the papillary dermis. It more often affects elderly women and is ...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463201302600423
更新日期:2013-10-01 00:00:00
abstract::We wanted to determine whether a paradigm switch in Th1/Th2 phenotypes in splenic lymphocytes could be induced in BALB/c mice after ultraviolet-B (UVB) irradiation and exposure to pollen. Results showed that UVB irradiation increased IL-1 but decreased IL-12 in vivo, and caused significant cell destruction of macropha...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract::Autoantibodies (rheumatoid factor, RF; anti-citrullinated-protein antibodies, ACPA) and complement system are involved in rheumatoid arthritis (RA). ACPA and anti-TNF agents are capable of in vitro modulating complement activity. We investigated the relationships between complement, autoantibodies, and anti-TNF treatm...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463201102400209
更新日期:2011-04-01 00:00:00
abstract::It is well known that in some conditions bacteria of physiological flora of gastrointestinal tract may become pathogenic. Each complaint which causes injury of gastrointestinal wall integrity permits bacteria to penetrate the tissues and affect the tissue cells. Since mast cells represent one of very important and num...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Paracrine mediators released from endothelial progenitor cells (EPCs) have been implicated in neoangiogenesis following ischemia. Recently, we demonstrated that microvesicles (MVs) derived from EPCs are able to activate an angiogenic program in quiescent endothelial cells by a horizontal transfer of RNA. In this study...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463201202500110
更新日期:2012-01-01 00:00:00
abstract::The narrow therapeutic index and large inter-individual variability in sirolimus pharmacokinetics (PK) make therapeutic drug monitoring (TDM) necessary. Factors responsible for PK variability are not well understood, and published PK studies do not include pediatric patients with immune cytopenia. The objective of thi...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/2058738420934936
更新日期:2020-01-01 00:00:00