Abstract:
:Cyclic AMP phosphodiesterase (cAMP PDE) seems to be important in pulp tissues. High levels of cAMP PDE have been demonstrated to be in dental pulp cells. In the present study cAMP PDE activity was analyzed in normal healthy human dental pulps, in reversible pulpitis and in irreversible pulpitis. Enzymatic cAMP PDE control values for normal healthy pulps were 12.14 +/- 3.74 nmols/mg of proteins. In reversible pulpitis the cAMP PDE activity increased almost 2.5 times. In irreversible pulpitis specimens the values increased 4.5 times compared with normal healthy pulps activity. The differences between the groups (control vs. reversible pulpitis and vs. irreversible pulpitis) were statistically significant. These results could point to a role of cAMP PDE in the initial pulp response after injury.
journal_name
Int J Immunopathol Pharmacolauthors
Spoto G,Menna V,Serra E,Santoleri F,Perfetti G,Ciavarelli L,Trentini Psubject
Has Abstractpub_date
2004-09-01 00:00:00pages
11-5issue
3 Suppleissn
0394-6320issn
2058-7384pii
3journal_volume
17pub_type
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