HLA-A2.1-restricted T cells react to SEREX-defined tumor antigen CML66L and are suppressed by CD4+CD25+ regulatory T cells.

abstract：:More and more studies have demonstrated the anti-inflammatory effects of heparin. However, in the aspect of allergic airway inflammation, data about its daily use in animal model is scarce. To evaluate the efficacy of 22-day intranasal heparin administration in mite-induced airway allergic inflammation in BALB/c mice,...

journal_title：International journal of immunopathology and pharmacology

authors： Fu LS,Tsai JJ,Chen YJ,Lin HK,Tsai MC,Chang MD

更新日期：2013-04-01 00:00:00

abstract：:Similar to many complex autoimmune diseases, genetic and environmental factors including diet, infection and xenobiotics play a critical role in the development of autism. In this study, we postulated that infectious agent antigens such as streptokinase, dietary peptides (gliadin and casein) and ethyl mercury (xenobio...

journal_title：International journal of immunopathology and pharmacology

authors： Vojdani A,Pangborn JB,Vojdani E,Cooper EL

更新日期：2003-09-01 00:00:00

abstract：:Involvement of imbalance between pro- and anti-inflammatory events has been reported in the developed pathogenesis after scorpion envenomation. The immunosuppressive and anti-inflammatory properties of tacrolimus (FK-506) have been investigated: i) to better understand evolution of signaling pathways which are involve...

journal_title：International journal of immunopathology and pharmacology

authors： Kabrine M,Laraba-Djebari F

更新日期：2014-01-01 00:00:00

abstract：:The aim of this experimental study was to evaluate the effects of nicotine on sperm motility and on non-conventional sperm parameters in vitro. Capacitated spermatozoa isolated from 10 normozoospermic, healthy, non-smoker men were evaluated. Spermatozoa were exposed to increasing concentrations of nicotine (0, 1, 10, ...

journal_title：International journal of immunopathology and pharmacology

authors： Condorelli RA,La Vignera S,Giacone F,Iacoviello L,Vicari E,Mongioi' L,Calogero AE

更新日期：2013-07-01 00:00:00

abstract：:Silicosis patients suffer from pulmonary fibrosis caused by silica inhalation, as well as autoimmune diseases known as the adjuvant effects of silica. Caplan syndrome complicated with rheumatoid arthritis (RA) is well known epidemiologically, and the incidence of complicated systemic sclerosis (SSc), systemic lupus er...

journal_title：International journal of immunopathology and pharmacology

authors： Otsuki T,Hayashi H,Nishimura Y,Hyodo F,Maeda M,Kumagai N,Miura Y,Kusaka M,Uragami K

更新日期：2011-01-01 00:00:00

abstract：:Nickel ingested with food can elicit either systemic cutaneous or gastrointestinal symptoms causing a systemic nickel allergy syndrome (SNAS) that can be treated with tolerance by oral ingestion of the metal. It has been suggested that interleukins 2 (IL-2) and 10 (IL-10) are involved in the mechanisms underlying oral...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardi L,Carni A,Loschiavo G,Gangemi S,Tigano V,Arena E,Mannucci C,Calapai G

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Inflammation, which is a hallmark of asthma, is one of the main sources of oxidative stress in the human body. Thiols are powerful antioxidants that protect cells against the consequences of oxidative stress. We aimed to investigate whether asthma and montelukast monotherapy affect the total plasma thiol poo...

journal_title：International journal of immunopathology and pharmacology

authors： Dilek F,Ozkaya E,Kocyigit A,Yazici M,Guler EM,Dundaroz MR

更新日期：2016-03-01 00:00:00

abstract：:The objective of the study is to verify effects of nebulized 3% saline hypertonic solution (HS) in comparison to normal saline (NS) in addition to epinephrine in hospitalized children with bronchiolitis. Infants were randomly assigned either to receive every 6 hours nebulized NS (group I) or 3% HS (group II) in additi...

journal_title：International journal of immunopathology and pharmacology

authors： Miraglia Del Giudice M,Saitta F,Leonardi S,Capasso M,Niglio B,Chinellato I,Decimo F,Maiello N,Capristo C,Perrone L,Peroni D

更新日期：2012-04-01 00:00:00

abstract：INTRODUCTION:Indoleamine 2,3-dioxygenase (IDO) was a potential tumor immunotherapy target. IDO inhibitors showed inconsistent results in clinical trials, but no preclinical comparative study was reported. The purpose of this study was to evaluate the differences of representative IDO inhibitors (PCC0208009, INCB024360,...

journal_title：International journal of immunopathology and pharmacology

authors： Jiang X,Li X,Zheng S,Du G,Ma J,Zhang L,Wang H,Tian J

更新日期：2020-01-01 00:00:00

abstract：:It is well known that in some conditions bacteria of physiological flora of gastrointestinal tract may become pathogenic. Each complaint which causes injury of gastrointestinal wall integrity permits bacteria to penetrate the tissues and affect the tissue cells. Since mast cells represent one of very important and num...

journal_title：International journal of immunopathology and pharmacology

authors： Brzezińska-Blaszczyk E,Olejnik AK

更新日期：1999-01-01 00:00:00

abstract：:In a preliminary study a reduction in natural killer (NK) cell activity in peripheral blood lymphocytes (PBL) was observed in a group of workers exposed to levels of extremely low frequency-magnetic fields (ELF-MF) exceeding 1 microT. This study was performed to confirm the results. In 121 workers engaged in various o...

journal_title：International journal of immunopathology and pharmacology

authors： Gobba F,Bargellini A,Bravo G,Scaringi M,Cauteruccio L,Borella P

更新日期：2009-10-01 00:00:00

abstract：:This study reports the immunomodulatory activity on human monocyte derived dendritic cells (MDDCs) of a vaccine preparation shown to be effective against an HPV16-related tumour in an animal model. The vaccine is composed of extract from Nicotiana benthamiana leaves containing HPV16 E7 protein expressed by a potato vi...

journal_title：International journal of immunopathology and pharmacology

authors： Di Bonito P,Grasso F,Mangino G,Massa S,Illiano E,Franconi R,Fanales-Belasio E,Falchi M,Affabris E,Giorgi C

更新日期：2009-10-01 00:00:00

abstract：:The role of profilin as an allergen has long been questioned. The capacity of profilin to induce respiratory symptoms has recently been demonstrated; moreover, over 50% of patients sensitized to profilin experienced symptoms after the ingestion of plant-derived foods, suggesting that profilin should be considered as a...

journal_title：International journal of immunopathology and pharmacology

authors： Nucera E,Aruanno A,Rizzi A,Pecora V,Patriarca G,Buonomo A,Mezzacappa S,Schiavino D

更新日期：2016-09-01 00:00:00

abstract：:Since the beginning of the 21st century, carbon-based nanomaterials (CNTs) have been introduced in pharmacy and medicine for drug delivery system in therapeutics. CNTs have proved able to transport a wide range of molecules across membranes and into living cells; therefore, they have attracted great interest in biomed...

journal_title：International journal of immunopathology and pharmacology

authors： Lamberti M,Pedata P,Sannolo N,Porto S,De Rosa A,Caraglia M

更新日期：2015-03-01 00:00:00

abstract：:Antimuscarinic drugs are the first line pharmacotherapy for overactive bladder, but they are not always effective to achieve complete continence. Nevertheless in some patients urodynamic investigations reveal insufficient effects with continuing incontinence events even with dose optimization. The aim of this study is...

journal_title：International journal of immunopathology and pharmacology

authors： Nardulli R,Losavio E,Ranieri M,Fiore P,Megna G,Bellomo RG,Cristella G,Megna M

更新日期：2012-01-01 00:00:00

abstract：:Human coronary artery endothelial cells (HCAEC 5156) were cultured as monolayers and exposed to concentrations of lead (as acetate, Pb) in the culture medium similar or lower than those commonly found in the blood of human beings occupationally or environmentally exposed to this element. Only at the concentration of 2...

journal_title：International journal of immunopathology and pharmacology

authors： Carmignani M,Felaco M,Boscolo P,Di Gioacchino M,Di Giampaolo L,Niu Q,Cesare P,Volpe AR

更新日期：2004-05-01 00:00:00

abstract：:We describe the case of a child affected by milk-protein induced enterocolitis, in which oral challenge with corn was performed without symptoms after a negative specific Atopy Patch Test. Food protein-induced enterocolitis syndrome (FPIES) is an uncommon nonIgE-mediated gastrointestinal food hypersensitivity of infan...

journal_title：International journal of immunopathology and pharmacology

authors： Scaparrotta A,Di Pillo S,Consilvio NP,Attanasi M,Cingolani A,Rapino D,Cerasa M,Pucci N,Di Gioacchino M,Chiarelli F

更新日期：2013-07-01 00:00:00

abstract：:In the present study we evaluated B-cell subsets and their functional development in 74 newborns from birth to 6 months of life. Moreover, we evaluated natural antibody production in vitro. The results documented a predominance of naive B-lymphocytes at all time-points evaluated, decreasing from birth to 6 months (p=0...

journal_title：International journal of immunopathology and pharmacology

authors： Avanzini MA,Maccario R,Belloni C,Carrera G,Bertaina A,Cagliuso M,La Rocca M,Valsecchi C,Mantelli M,Castellazzi AM,Quinti I,De Silvestri A,Marconi M

更新日期：2010-01-01 00:00:00

abstract：:Immunosuppressive treatment has changed the prognosis of Lupus nephritis over time, but improvement in prognosis is difficult to analyze in different historical periods, and should be better demonstrated in comparison with life expectancy of sex-and age-matched people. Long-term patient and renal survival of 90 patien...

journal_title：International journal of immunopathology and pharmacology

authors： Stratta P,Mesiano P,Campo A,Grill A,Ferrero S,Santi S,Besso L,Mazzucco G,Rosso S,Spitale A,Fop F,Ciccone G

更新日期：2009-10-01 00:00:00

abstract：:Plague is still endemic in different regions of the world. Current vaccines raise concern for their side effects and limited protection, highlighting the need for an efficacious and rapidly producible vaccine. F1 and V antigens of Yersinia pestis, and F1-V fusion protein produced in Nicotiana benthamiana administered ...

journal_title：International journal of immunopathology and pharmacology

authors： Del Prete G,Santi L,Andrianaivoarimanana V,Amedei A,Domarle O,D' Elios MM,Arntzen CJ,Rahalison L,Mason HS

更新日期：2009-01-01 00:00:00

abstract：:Regulatory T cells (Treg) play a critical role in immune homeostasis and expansion of Treg is controlled by chemokine receptors. The chemokine CXCL12 and its G-protein-coupled receptor (CXCR4) are involved in the development of idiopathic pulmonary fibrosis (IPF), but the association of Treg with the CXCL12/CXCR4 axis...

journal_title：International journal of immunopathology and pharmacology

authors： Shimizu Y,Dobashi K,Endou K,Ono A,Yanagitani N,Utsugi M,Sano T,Ishizuka T,Shimizu K,Tanaka S,Mori M

更新日期：2010-04-01 00:00:00

abstract：:We present a clinical case report regarding recurrent atrial fibrillation in a patient with ulcerative colitis treated with azathioprine. Atrial fibrillation represents the most common sustained cardiac arrhythmia, occurring in 1-2% of the general population and characterized by seemingly disorganized atrial depolariz...

journal_title：International journal of immunopathology and pharmacology

authors： Riccioni G,Bucciarelli V,Di Ilio E,Scotti L,Aceto A,D'Orazio N,Martini F,Bucciarelli T

更新日期：2011-01-01 00:00:00

abstract：:We describe the case of a 30-year-old female with no family history of psoriasis and suffering from Crohn's disease successfully treated with infliximab at the dosage of 5 mg/kg. On the 15th week from the start of therapy, the patient developed a palmoplantar pustular psoriasis, which spread to the arms, trunk and sca...

journal_title：International journal of immunopathology and pharmacology

authors： Manni E,Barachini P

更新日期：2009-07-01 00:00:00

abstract：:The aim of this study was to investigate the possible protective effects of diallyl trisulfide (DATS) against naphthalene-induced oxidative and inflammatory damage in the livers and lungs of mice. Elevated serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels showed significant hepatic damag...

journal_title：International journal of immunopathology and pharmacology

authors： Zhang F,Zhang Y,Wang K,Liu G,Yang M,Zhao Z,Li S,Cai J,Cao J

更新日期：2016-06-01 00:00:00

abstract：:We aimed to analyze the action of berberine on the neuropathic pain and neuroglia activation in experimental diabetes mellitus (DM) model. Diabetes in mice was induced by intraperitoneal injection of streptozotocin (STZ) followed by the administration of berberine. Mechanical allodynia and thermal hyperalgesia and act...

journal_title：International journal of immunopathology and pharmacology

authors： Liu M,Gao L,Zhang N

更新日期：2019-01-01 00:00:00

abstract：:HSP60 has been implicated in chronic inflammatory disease pathogenesis, including chronic obstructive pulmonary disease (COPD), but the mechanisms by which this chaperonin would act are poorly understood. A number of studies suggest a role for extracellular HSP60, since it can be secreted from cells and bind Toll-like...

journal_title：International journal of immunopathology and pharmacology

authors： Sangiorgi C,Vallese D,Gnemmi I,Bucchieri F,Balbi B,Brun P,Leone A,Giordano A,Conway de Macario E,Macario AJ,Cappello F,Di Stefano A

更新日期：2017-12-01 00:00:00

abstract：:Septic shock (SS) leads to a high mortality rate for sepsis patients. Norepinephrine (NE) is a preferred vasoactive agent in SS treatment. This study aimed to assess the effects of NE at different administration time and NE combined with SP treatment on the cardiac function and prognosis of SS.SS patients received NE ...

journal_title：International journal of immunopathology and pharmacology

authors： Kang D,Yu J,Xia J,Li X,Wang H,Zhao Y

更新日期：2020-01-01 00:00:00

abstract：:Ionizing irradiation causes damage and functional failure of irradiation-sensitive systems and tissues such as small intestine. The molecular mechanisms underlying inflammatory and adaptive responses to acute irradiation damage are poorly understood. Using a mouse model of total-body γ-irradiation, we assessed the irr...

journal_title：International journal of immunopathology and pharmacology

authors： Gorbunov NV,Garrison BR,Kiang JG

更新日期：2010-10-01 00:00:00

abstract：:Ink spot lentigo, also known as reticulated black solar lentigo, is a melanotic macula commonly described in fair-skinned individuals on sun-exposed areas of the body. Clinically it is a darkly pigmented type of solar lentigo; herein the term ink spot lentigo. In contrast to common solar lentigines, ink spot lentigo i...

journal_title：International journal of immunopathology and pharmacology

authors： Bottoni U,Nisticò S,Amoruso GF,Schipani G,Arcidiacono V,Scali E,Tassone P,Greco M,Amorosi A

更新日期：2013-10-01 00:00:00

abstract：:The aims of the present study were: (i) to assess whether H. pylori could be successfully detected by PCR from the same biopsy sample used for CPtest; and ii) to evaluate CPtest comparatively to both PCR and histology for detection of H. pylori infection in dyspeptic patients. Three antral gastric biopsies were collec...

journal_title：International journal of immunopathology and pharmacology

authors： Di Bonaventura G,Neri M,Angelucci D,Rosini S,Piccolomini M,Piccolomini R

更新日期：2004-01-01 00:00:00