Low levels of serum cholesterol/phospholipids are associated with the antiphospholipid antibodies in monoclonal gammopathy.

abstract：:The aim of this study was to evaluate the effect of the Heat Shock Proteins GroES, GroEL and DnaK on the expression of the costimulatory molecules CD80/CD86 in B cells and macrophages. The interactions among these molecules are able to highly influence the immune response through the regulation of cytokine liberation ...

journal_title：International journal of immunopathology and pharmacology

authors： Galdiero M,Pisciotta MG,Gorga F,Petrillo G,Marinelli A,Galdiero E

更新日期：2005-10-01 00:00:00

abstract：:The aims of the present study were: (i) to assess whether H. pylori could be successfully detected by PCR from the same biopsy sample used for CPtest; and ii) to evaluate CPtest comparatively to both PCR and histology for detection of H. pylori infection in dyspeptic patients. Three antral gastric biopsies were collec...

journal_title：International journal of immunopathology and pharmacology

authors： Di Bonaventura G,Neri M,Angelucci D,Rosini S,Piccolomini M,Piccolomini R

更新日期：2004-01-01 00:00:00

abstract：:Cryopyrin-associated periodic syndromes are categorized as a spectrum of three autoinflammatory diseases, namely familial cold auto-inflammatory syndrome, Muckle-Wells syndrome and chronic infantile neurological cutaneous articular syndrome. All are caused by mutations in the NLRP3 gene coding for cryopyrin and result...

journal_title：International journal of immunopathology and pharmacology

authors： Cantarini L,Lucherini OM,Frediani B,Brizi MG,Bartolomei B,Cimaz R,Galeazzi M,Rigante D

更新日期：2011-10-01 00:00:00

abstract：:The expression of Ikaros family transcription factors and consequently their signalling pathway is limiting for hematopoietic and lymphocyte development in mice and human. Due to their importance, these transcription factors are highly homologous between species. As an initial approach to examining the possible involv...

journal_title：International journal of immunopathology and pharmacology

authors： Paradzik M,Novak S,Mokrovic G,Bordukalo Niksic T,Heckel D,Stipic J,Pavicic Baldani D,Cicin-Sain L,Antica M

更新日期：2012-10-01 00:00:00

abstract：:There is still no "gold standard" for the diagnosis and prognosis of post-operative periprosthetic joint infection (PJI). Among serum biomarkers, an emerging molecule is presepsin, the soluble fraction of CD14, recently described in other settings as a powerful diagnostic tool to detect sepsis at different degrees of ...

journal_title：International journal of immunopathology and pharmacology

authors： Marazzi MG,Randelli F,Brioschi M,Drago L,Romanò CL,Banfi G,Massaccesi L,Crapanzano C,Morelli F,Corsi Romanelli MM,Galliera E

更新日期：2018-01-01 00:00:00

abstract：:In order to understand the immunogenicity of a tumor-associated antigen (TAA), Ras family small GTP binding protein (Ra1A) in hepatocellular carcinoma (HCC), autoantibody responses to RalA were evaluated by enzyme-linked immunosorbent assay (ELISA), Western blotting and indirect immunofluorescence assay in sera from p...

journal_title：International journal of immunopathology and pharmacology

authors： Wang K,Chen Y,Liu S,Qiu S,Gao S,Huang X,Zhang J,Peng X,Qiani W,Zhang JY

更新日期：2009-07-01 00:00:00

abstract：:IgG4 have been hypothesized to act as blocking antibodies capable of preventing IgE-mediated effector cell triggering. This study aims to evaluate the changes in IgG4 in children during a period of natural antigen avoidance. Serum IgE and IgG4 were evaluated in a group of asthmatic children, aged between 7 and 17 year...

journal_title：International journal of immunopathology and pharmacology

authors： Piacentini GL,Guerresi S,Kantar A,Lubrano L,Olivieri F,Boner AL,Peroni DG

更新日期：2011-10-01 00:00:00

abstract：:Both allergic disorders and obesity keep increasing in industrialized countries. Even though a strong association between obesity and allergy- related diseases has been reported in several studies, no published data show a scientific and firm link in-between the two conditions. In general, obesity and weight gain have...

journal_title：International journal of immunopathology and pharmacology

authors： Ciprandi G,Caimmi D,Raschetti R,Miraglia Del Giudice M,Salpietro C,Caimmi S,Castellazzi AM

更新日期：2011-10-01 00:00:00

abstract：:The narrow therapeutic index and large inter-individual variability in sirolimus pharmacokinetics (PK) make therapeutic drug monitoring (TDM) necessary. Factors responsible for PK variability are not well understood, and published PK studies do not include pediatric patients with immune cytopenia. The objective of thi...

journal_title：International journal of immunopathology and pharmacology

authors： Cheng X,Zhao Y,Gu H,Zhao L,Zang Y,Wang X,Wu R

更新日期：2020-01-01 00:00:00

abstract：:Malacoplakia is a rare inflammatory condition characterized by the accumulation of benign macrophages associated with pathognomonic Michaelis-Gutmann bodies (MGBs). It is usually found in the genito-urinary tract, and has been associated with immunocompromised states. In this short report, we present 5 patients with p...

journal_title：International journal of immunopathology and pharmacology

authors： Mulè A,Petrone G,Santoro A,Sanguinetti M,Meacci E,Coli A,Margaritora S

更新日期：2012-07-01 00:00:00

abstract：:Calligonum polygonoides is locally called as Phog which belongs to the Polygonaceae family. It is traditionally used as an antifungal. The methanolic extract, hexane extract, ethyl acetate extract and aqueous extract were screened against Candida albicans and Aspergillus niger in seven concentrations, that is, 1.8, 2....

journal_title：International journal of immunopathology and pharmacology

authors： Ahmad S,Akram M

更新日期：2019-01-01 00:00:00

abstract：:An association between human immunodeficiency virus type I (HIV-1) protease inhibitors (PIs) and galactorrhoea/hyperprolactinemia adverse effect has recently been reported in four HIV-1-infected women treated with PIs (indinavir, nelfinavir, ritonavir or saquinavir). This could be explained by a direct effect of riton...

journal_title：International journal of immunopathology and pharmacology

authors： Orlando G,Brunetti L,Vacca M

更新日期：2002-01-01 00:00:00

abstract：:The beneficial effects of hot springs have been known for centuries and treatments with sulphurous thermal waters are recommended in a number of chronic pathologies as well as acute recurrent infections. However, the positive effects of the therapy are often evaluated in terms of subjective sense of wellbeing and symp...

journal_title：International journal of immunopathology and pharmacology

authors： Prandelli C,Parola C,Buizza L,Delbarba A,Marziano M,Salvi V,Zacchi V,Memo M,Sozzani S,Calza S,Uberti D,Bosisio D

更新日期：2013-07-01 00:00:00

abstract：:Nasal cytology represents a valid method in the differential diagnosis of allergic and non-allergic nasal diseases, as it is simple, safe, non-invasive, cost-effective, and easy to perform both in the medical and paediatric office. In particular, through cytological investigation it is possible to diagnose a group of ...

journal_title：International journal of immunopathology and pharmacology

authors： Gelardi M,Fiorella ML,Russo C,Fiorella R,Ciprandi G

更新日期：2010-01-01 00:00:00

abstract：:Chemokines and their receptors have been implicated in cell migration and metastasis of multiple malignant tumors. But the function of CXCR6 signaling in gastric cancer is not comprehensively understood. In the present study, we hypothesized that CXCR6 signaling might play an essential role in the progression of gastr...

journal_title：International journal of immunopathology and pharmacology

authors： Li Y,Fu LX,Zhu WL,Shi H,Chen LJ,Ye B

更新日期：2015-06-01 00:00:00

abstract：:Mast cells are vital mediators of drug allergy and, therefore, studying the relationship between drug allergy and mast cells is essential. Sinomenine is the principal active component of Sinomenium acutum, which has anti-inflammatory and anti-immune effects, and is used to treat various rheumatoid diseases. However, al...

journal_title：International journal of immunopathology and pharmacology

authors： Wang N,Liu R,Liu Y,Zhang R,He L

更新日期：2016-12-01 00:00:00

abstract：:Many oncogenis and tumour suppressor genes found inside normal and pathological cells are fundamental for the processes of development, proliferation and tissue differentiation. The purpose of our study is to show the presence and a possible relationship of the VEGF protein during different phases of the development o...

journal_title：International journal of immunopathology and pharmacology

authors： Mastrangelo F,Piccirilli M,Dolci M,Teté S,Speranza L,Patruno A,Gizzi F,Felaco M,Artese L,De Lutiis MA

更新日期：2005-07-01 00:00:00

abstract：:Atopic dermatitis (AD) is a chronic inflammatory disease of the skin that substantially affects a patient's quality of life. While steroids are the most common therapy used to temporally alleviate the symptoms of AD, effective and nontoxic alternatives are urgently needed. In this study, we utilized a natural, plant-d...

journal_title：International journal of immunopathology and pharmacology

authors： Wu CS,Lin SC,Li S,Chiang YC,Bracci N,Lehman CW,Tang KT,Lin CC

更新日期：2020-01-01 00:00:00

abstract：:Regulatory T cells (Treg) play a critical role in immune homeostasis and expansion of Treg is controlled by chemokine receptors. The chemokine CXCL12 and its G-protein-coupled receptor (CXCR4) are involved in the development of idiopathic pulmonary fibrosis (IPF), but the association of Treg with the CXCL12/CXCR4 axis...

journal_title：International journal of immunopathology and pharmacology

authors： Shimizu Y,Dobashi K,Endou K,Ono A,Yanagitani N,Utsugi M,Sano T,Ishizuka T,Shimizu K,Tanaka S,Mori M

更新日期：2010-04-01 00:00:00

abstract：:We describe the case of a child affected by milk-protein induced enterocolitis, in which oral challenge with corn was performed without symptoms after a negative specific Atopy Patch Test. Food protein-induced enterocolitis syndrome (FPIES) is an uncommon nonIgE-mediated gastrointestinal food hypersensitivity of infan...

journal_title：International journal of immunopathology and pharmacology

authors： Scaparrotta A,Di Pillo S,Consilvio NP,Attanasi M,Cingolani A,Rapino D,Cerasa M,Pucci N,Di Gioacchino M,Chiarelli F

更新日期：2013-07-01 00:00:00

abstract：:The treatment with infliximab is employed successfully in Crohn's disease (CD) but predictors of efficacy are lacking. Activation of the transcription factor NF-kB has been demonstrated in CD and its inhibition is one of the mechanisms by which anti-inflammatory agents exert their effects. We evaluated the production ...

journal_title：International journal of immunopathology and pharmacology

authors： Guidi L,Costanzo M,Ciarniello M,De Vitis I,Pioli C,Gatta L,Pace L,Tricerri A,Bartoloni C,Coppola L,Balistreri P,Doria G,Fedeli G,Gasbarrini GB

更新日期：2005-01-01 00:00:00

abstract：:Extranodal non-Hodgkin lymphomas limited to the larynx are rare, accounting for less than 1% of all laryngeal neoplasms. The most common site of development of primary laryngeal lymphomas is the supraglottic region. In most cases, the presenting symptoms are hoarseness, dysphagia, dyspnea, and cervical lymphadenopathy...

journal_title：International journal of immunopathology and pharmacology

authors： Zapparoli M,Trolese AR,Remo A,Sina S,Bonetti A,Micheletto C

更新日期：2014-07-01 00:00:00

abstract：:We reported a case of an 11-year-old girl admitted to our hospital for goiter, tachycardia, sweating, and visible and palpable thyroid. Thyroid function tests revealed a low thyrotropin level (<0.004 mIU/L) and elevated free thyroxine level (3.4 ng/ dL) diagnosed with Graves' disease and treated with methimazole. This...

journal_title：International journal of immunopathology and pharmacology

authors： Arrigo T,Cutroneo PM,Vaccaro M,Impollonia D,Squadrito V,Mecchio A,Salpietro C,Altavilla D

更新日期：2016-12-01 00:00:00

abstract：:Serum samples from Bulgarian patients with physician-diagnosed erythema migrans (EM) (n=105) were examined using Borrelia burgdorferi ELISA (Boehring, Germany) after previous absorption with Treponema phagedenis. For IgM antibody detection sera were additionally pretreated with anti-IgG serum (RF absorbent). Serum sam...

journal_title：International journal of immunopathology and pharmacology

authors： Christova I

更新日期：2003-09-01 00:00:00

abstract：:Since the beginning of the 21st century, carbon-based nanomaterials (CNTs) have been introduced in pharmacy and medicine for drug delivery system in therapeutics. CNTs have proved able to transport a wide range of molecules across membranes and into living cells; therefore, they have attracted great interest in biomed...

journal_title：International journal of immunopathology and pharmacology

authors： Lamberti M,Pedata P,Sannolo N,Porto S,De Rosa A,Caraglia M

更新日期：2015-03-01 00:00:00

abstract：:Blockade of the interactions between CD28/CTLA-4 and their ligands, CD80 (B7, B7.1)/CD86 (B70, B7.2), is an attractive means to induce antigen-specific peripheral tolerance in autoimmune disease and organ transplantation. In this study, we generated and characterized a monoclonal antibody (Clone 4E5) against human CD8...

journal_title：International journal of immunopathology and pharmacology

authors： Shi Q,Gao ZY,Xie F,Wang LF,Gu YP,Yang TJ,Huang L,Qian QH,Qiu YH

更新日期：2011-07-01 00:00:00

abstract：:Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its s...

journal_title：International journal of immunopathology and pharmacology

authors： Castellani ML,Felaco P,Galzio RJ,Tripodi D,Toniato E,De Lutiis MA,Fulcheri M,Caraffa A,Antinolfi P,Tetè S,Felaco M,Conti F,Pandolfi F,Theoharides TC,Shaik-Dasthagirisaheb YB

更新日期：2010-07-01 00:00:00

abstract：:Human coronary artery endothelial cells (HCAEC 5156) were cultured as monolayers and exposed to concentrations of lead (as acetate, Pb) in the culture medium similar or lower than those commonly found in the blood of human beings occupationally or environmentally exposed to this element. Only at the concentration of 2...

journal_title：International journal of immunopathology and pharmacology

authors： Carmignani M,Felaco M,Boscolo P,Di Gioacchino M,Di Giampaolo L,Niu Q,Cesare P,Volpe AR

更新日期：2004-05-01 00:00:00

abstract：:Epithelial mesenchymal transformation is considered a cardinal process in orofacial development. Several molecular players appear to be involved in this delicate mechanism; the activation of LEF1 transcription factor by transforming growth factor beta 3 seems to be a key step for the correct flow of events. The failur...

journal_title：International journal of immunopathology and pharmacology

authors： Martinelli M,Carinci F,Morselli PG,Caramelli E,Palmieri A,Girardi A,Riberti C,Scapoli L

更新日期：2011-04-01 00:00:00

abstract：:Mast cells play important role in allergic inflammation by releasing histamine, tryptase and several inflammatory cytokines. Human leukemic mast cells (HMC-1) have been used to study mast cell mediator and their role in inflammatory mechanisms. HMC-1 contain and release several inflammatory mediators, of which the pro...

journal_title：International journal of immunopathology and pharmacology

authors： Alexandrakis MG,Kyriakou DS,Seretakis D,Boucher W,Letourneau R,Kempuraj D,Theoharides TC

更新日期：2003-01-01 00:00:00