IL-31 a Th2 cytokine involved in immunity and inflammation.

Abstract:

:Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its surface receptor. This cytokine is also produced by mast cells and mast cell line, suggesting a role in allergic diseases. In this editorial we revisit the biological role of IL-31 in immunity and inflammation.

authors

Castellani ML,Felaco P,Galzio RJ,Tripodi D,Toniato E,De Lutiis MA,Fulcheri M,Caraffa A,Antinolfi P,Tetè S,Felaco M,Conti F,Pandolfi F,Theoharides TC,Shaik-Dasthagirisaheb YB

doi

10.1177/039463201002300304

subject

Has Abstract

pub_date

2010-07-01 00:00:00

pages

709-13

issue

3

eissn

0394-6320

issn

2058-7384

pii

4

journal_volume

23

pub_type

社论
  • Characteristic patterns of HLA presentation and T cell differentiation in adult-onset Still's disease.

    abstract::We examined the expression of human leukocyte antigen (HLA) and composition of differentiated T cells in the peripheral blood to understand the characteristics of the immune changes in patients with adult-onset Still's disease (AOSD). This study enrolled patients with AOSD (n = 14), patients with rheumatoid arthritis ...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/2058738418791284

    authors: Jung JY,Choi B,Sayeed HM,Suh CH,Kim YW,Kim HA,Sohn S

    更新日期:2018-01-01 00:00:00

  • Aberrant miR-219-5p is correlated with TLR4 and serves as a novel biomarker in patients with multiple organ dysfunction syndrome caused by acute paraquat poisoning.

    abstract::This study aimed to investigate the clinical significance of serum microRNA-219-5p (miR-219-5p) in patients with multiple organ dysfunction syndrome (MODS) caused by acute paraquat (PQ) poisoning, and its correlation with Toll-like Receptor 4 (TLR4). Luciferase reporter assay was used to investigate in vitro the corre...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/2058738420974888

    authors: Dai Y,Liu X,Gao Y

    更新日期:2020-01-01 00:00:00

  • Increased levels of IGF-1 and beta2-microglobulin in epithelial lining fluid of preterm newborns developing chronic lung disease. effects of rhG-CSF.

    abstract:UNLABELLED:Insulin-like growth factor-1 (IGF-1) is involved in regulating the Th-1/Th-2 balance, favoring the development of the Th-2 compartment which enhances fibrosis, one of the main characteristics of Chronic Lung Disease (CLD) in premature newborns. Limited data is available concerning a possible association betw...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:

    authors: Capoluongo E,Vento G,Ameglio F,Lulli P,Matassa PG,Carrozza C,Santini SA,Antenucci M,Castagnola M,Giardina B,Romagnoli C,Zuppi C

    更新日期:2006-01-01 00:00:00

  • A pilot study of feasibility of ultra-rush (20-25 minutes) sublingual-swallow immunotherapy in 679 patients (699 sessions) with allergic rhinitis and/or asthma.

    abstract::Few studies have evaluated the occurrence of immediate adverse reactions in allergic patients after an ultra-rush regimen of different commercial allergen extracts for sublingual immunotherapy (SLIT) Methods: 679 patients took part in trials of specific ultra-rush SLIT for the treatment of IgE-mediated rhinitis and/or...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 临床试验,杂志文章

    doi:10.1177/039463200501800210

    authors: Rossi RE,Monasterolo G

    更新日期:2005-04-01 00:00:00

  • Interstitial cystitis and infectious agents.

    abstract::Interstitial cystitis (IC) is a syndrome consisting of severe refractory bladder symptoms of unknown etiology. The disease tends to affect Caucasian women with a mean age of 40 years, with 25% of patients under the age of 30. Few population based epidemiological studies of IC have been performed. We analyzed a case of...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200501800424

    authors: Fioriti D,Penta M,Mischitelli M,Degener AM,Pierangeli A,Gentile V,Nicosia R,Gallinelli C,Chiarini F,Pietropaolo V

    更新日期:2005-10-01 00:00:00

  • Strategies for successful vaccination against hepatocellular carcinoma.

    abstract::Current therapies against hepatocellular carcinoma (HCC) are not curative in the majority of patients. In the past, immunotherapy approaches aimed to non-specifically stimulate immune response were quite ineffective. New treatments based on stimulation of specific anti-tumor immune response are currently proposed and ...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 社论

    doi:10.1177/039463200902200203

    authors: Rinaldi M,Iurescia S,Fioretti D,Ponzetto A,Carloni G

    更新日期:2009-04-01 00:00:00

  • Natural killer cell activity decreases in workers occupationally exposed to extremely low frequency magnetic fields exceeding 1 microT.

    abstract::In a preliminary study a reduction in natural killer (NK) cell activity in peripheral blood lymphocytes (PBL) was observed in a group of workers exposed to levels of extremely low frequency-magnetic fields (ELF-MF) exceeding 1 microT. This study was performed to confirm the results. In 121 workers engaged in various o...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200902200422

    authors: Gobba F,Bargellini A,Bravo G,Scaringi M,Cauteruccio L,Borella P

    更新日期:2009-10-01 00:00:00

  • Detection of Helicobacter pylori by PCR on gastric biopsy specimens taken for CP test: comparison with histopathological analysis.

    abstract::The aims of the present study were: (i) to assess whether H. pylori could be successfully detected by PCR from the same biopsy sample used for CPtest; and ii) to evaluate CPtest comparatively to both PCR and histology for detection of H. pylori infection in dyspeptic patients. Three antral gastric biopsies were collec...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200401700111

    authors: Di Bonaventura G,Neri M,Angelucci D,Rosini S,Piccolomini M,Piccolomini R

    更新日期:2004-01-01 00:00:00

  • Enhancement of lysosomal glycohydrolase activity in human primary B lymphocytes during spontaneous apoptosis.

    abstract::It has been shown that lysosomes are involved in B cell apoptosis but lysosomal glycohydrolases have never been investigated during this event. In this study we determined the enzymatic activities of some lysosomal glycohydrolases in human tonsil B lymphocytes (TBL) undergoing in vitro spontaneous apoptosis. Fluorimet...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200702000208

    authors: Rosati E,Mencarelli S,Magini A,Sabatini R,Tassi C,Orlacchio A,Coaccioli S,Frenguelli A,Marconi P,Emiliani C

    更新日期:2007-04-01 00:00:00

  • Determinants of bronchial hyperresponsiveness in subjects with rhinitis.

    abstract::Subjects with rhinitis but without asthma may have coexisting bronchial hyperresponsiveness, although the reasons for this are uncertain. To evaluate the factors that determine BHR in rhinitis we examined 410 patients with symptomatic rhinitis with forced expiratory volume in 1 second (FEV1) and forced vital capacity ...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200501800414

    authors: Di Lorenzo G,Pacor ML,Mansueto P,Esposito Pellitteri M,Lo Bianco C,Ditta V,Leto-Barone MS,Napoli N,Di Fede G,Rini GB

    更新日期:2005-10-01 00:00:00

  • Blockade of CXCR6 reduces invasive potential of gastric cancer cells through inhibition of AKT signaling.

    abstract::Chemokines and their receptors have been implicated in cell migration and metastasis of multiple malignant tumors. But the function of CXCR6 signaling in gastric cancer is not comprehensively understood. In the present study, we hypothesized that CXCR6 signaling might play an essential role in the progression of gastr...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/0394632015584502

    authors: Li Y,Fu LX,Zhu WL,Shi H,Chen LJ,Ye B

    更新日期:2015-06-01 00:00:00

  • Infections, toxic chemicals and dietary peptides binding to lymphocyte receptors and tissue enzymes are major instigators of autoimmunity in autism.

    abstract::Similar to many complex autoimmune diseases, genetic and environmental factors including diet, infection and xenobiotics play a critical role in the development of autism. In this study, we postulated that infectious agent antigens such as streptokinase, dietary peptides (gliadin and casein) and ethyl mercury (xenobio...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200301600302

    authors: Vojdani A,Pangborn JB,Vojdani E,Cooper EL

    更新日期:2003-09-01 00:00:00

  • Endothelial progenitor cell-derived microvesicles improve neovascularization in a murine model of hindlimb ischemia.

    abstract::Paracrine mediators released from endothelial progenitor cells (EPCs) have been implicated in neoangiogenesis following ischemia. Recently, we demonstrated that microvesicles (MVs) derived from EPCs are able to activate an angiogenic program in quiescent endothelial cells by a horizontal transfer of RNA. In this study...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201202500110

    authors: Ranghino A,Cantaluppi V,Grange C,Vitillo L,Fop F,Biancone L,Deregibus MC,Tetta C,Segoloni GP,Camussi G

    更新日期:2012-01-01 00:00:00

  • Acute impact of volcanic ash on asthma symptoms and treatment.

    abstract::Information about the impacts of disasters on health is useful for establishing hazard prediction maps and action plans of disaster management. This study aims at learning effective asthma management from the volcano disaster of Mount Asama eruption in Japan on September 1, 2004. We conducted a cross-sectional study t...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/03946320070200S203

    authors: Shimizu Y,Dobashi K,Hisada T,Ono A,Todokoro M,Iijima H,Utsugi M,Kakegawa S,Iizuka K,Ishizuka T,Morikawa A,Mori M

    更新日期:2007-04-01 00:00:00

  • A comparison between IgE and IgG4 as markers of allergy in children: an experimental trial in a model of natural antigen avoidance.

    abstract::IgG4 have been hypothesized to act as blocking antibodies capable of preventing IgE-mediated effector cell triggering. This study aims to evaluate the changes in IgG4 in children during a period of natural antigen avoidance. Serum IgE and IgG4 were evaluated in a group of asthmatic children, aged between 7 and 17 year...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201102400422

    authors: Piacentini GL,Guerresi S,Kantar A,Lubrano L,Olivieri F,Boner AL,Peroni DG

    更新日期:2011-10-01 00:00:00

  • Infection following bone tumor resection and reconstruction with tumoral prostheses: a literature review.

    abstract::Bone resection is the choice treatment of malignant bone tumors. Tumor prosthesis is one of the most common solutions of reconstruction following resection of bone tumor located to the metaphysis of long bones. Periprosthetic infections are a frequent complication of limb-salvage surgery which is largely due to prolon...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 社论,评审

    doi:10.1177/039463201002300405

    authors: Graci C,Maccauro G,Muratori F,Spinelli MS,Rosa MA,Fabbriciani C

    更新日期:2010-10-01 00:00:00

  • Effectiveness of nebulized hypertonic saline and epinephrine in hospitalized infants with bronchiolitis.

    abstract::The objective of the study is to verify effects of nebulized 3% saline hypertonic solution (HS) in comparison to normal saline (NS) in addition to epinephrine in hospitalized children with bronchiolitis. Infants were randomly assigned either to receive every 6 hours nebulized NS (group I) or 3% HS (group II) in additi...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 信件,随机对照试验

    doi:10.1177/039463201202500218

    authors: Miraglia Del Giudice M,Saitta F,Leonardi S,Capasso M,Niglio B,Chinellato I,Decimo F,Maiello N,Capristo C,Perrone L,Peroni D

    更新日期:2012-04-01 00:00:00

  • Modulation of costimulatory molecules CD80/CD86 on B cells and macrophages by stress proteins GroEL, GroES and DnaK.

    abstract::The aim of this study was to evaluate the effect of the Heat Shock Proteins GroES, GroEL and DnaK on the expression of the costimulatory molecules CD80/CD86 in B cells and macrophages. The interactions among these molecules are able to highly influence the immune response through the regulation of cytokine liberation ...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200501800404

    authors: Galdiero M,Pisciotta MG,Gorga F,Petrillo G,Marinelli A,Galdiero E

    更新日期:2005-10-01 00:00:00

  • The first study in pediatric: Population pharmacokinetics of sirolimus and its application in Chinese children with immune cytopenia.

    abstract::The narrow therapeutic index and large inter-individual variability in sirolimus pharmacokinetics (PK) make therapeutic drug monitoring (TDM) necessary. Factors responsible for PK variability are not well understood, and published PK studies do not include pediatric patients with immune cytopenia. The objective of thi...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/2058738420934936

    authors: Cheng X,Zhao Y,Gu H,Zhao L,Zang Y,Wang X,Wu R

    更新日期:2020-01-01 00:00:00

  • Plasma total thiol pool in children with asthma: Modulation during montelukast monotherapy.

    abstract:BACKGROUND:Inflammation, which is a hallmark of asthma, is one of the main sources of oxidative stress in the human body. Thiols are powerful antioxidants that protect cells against the consequences of oxidative stress. We aimed to investigate whether asthma and montelukast monotherapy affect the total plasma thiol poo...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/0394632015621563

    authors: Dilek F,Ozkaya E,Kocyigit A,Yazici M,Guler EM,Dundaroz MR

    更新日期:2016-03-01 00:00:00

  • Type 1 diabetes onset and pandemic influenza A (H1N1).

    abstract::Type 1 diabetes (T1D) is a heterogeneous disorder characterized by destruction of pancreatic beta cells, culminating in loss of insulin secretion. Data from large epidemiologic studies worldwide indicate that during the last decades the incidence of T1D has increased significantly, reaching percentages of 2-5% annuall...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 评论,信件

    doi:10.1177/039463201202500228

    authors: Piccini B,Toni S,Lenzi L,Guasti M,Barni F,De Martino M

    更新日期:2012-04-01 00:00:00

  • Role of nasal cytology.

    abstract::Nasal cytology represents a valid method in the differential diagnosis of allergic and non-allergic nasal diseases, as it is simple, safe, non-invasive, cost-effective, and easy to perform both in the medical and paediatric office. In particular, through cytological investigation it is possible to diagnose a group of ...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章,评审

    doi:

    authors: Gelardi M,Fiorella ML,Russo C,Fiorella R,Ciprandi G

    更新日期:2010-01-01 00:00:00

  • Phloretin alleviates dinitrochlorobenzene-induced dermatitis in BALB/c mice.

    abstract::Atopic dermatitis (AD) is a chronic inflammatory disease of the skin that substantially affects a patient's quality of life. While steroids are the most common therapy used to temporally alleviate the symptoms of AD, effective and nontoxic alternatives are urgently needed. In this study, we utilized a natural, plant-d...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/2058738420929442

    authors: Wu CS,Lin SC,Li S,Chiang YC,Bracci N,Lehman CW,Tang KT,Lin CC

    更新日期:2020-01-01 00:00:00

  • Evidence of LEF1 fetal-maternal interaction in cleft lip with or without cleft palate in a consistent Italian sample study.

    abstract::Epithelial mesenchymal transformation is considered a cardinal process in orofacial development. Several molecular players appear to be involved in this delicate mechanism; the activation of LEF1 transcription factor by transforming growth factor beta 3 seems to be a key step for the correct flow of events. The failur...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/03946320110240S204

    authors: Martinelli M,Carinci F,Morselli PG,Caramelli E,Palmieri A,Girardi A,Riberti C,Scapoli L

    更新日期:2011-04-01 00:00:00

  • Pulmonary malacoplakia at early stage: use of polymerase chain reaction for detection of Rhodococcus equi.

    abstract::Malacoplakia is a rare inflammatory condition characterized by the accumulation of benign macrophages associated with pathognomonic Michaelis-Gutmann bodies (MGBs). It is usually found in the genito-urinary tract, and has been associated with immunocompromised states. In this short report, we present 5 patients with p...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201202500316

    authors: Mulè A,Petrone G,Santoro A,Sanguinetti M,Meacci E,Coli A,Margaritora S

    更新日期:2012-07-01 00:00:00

  • Reduced sebum production in Turner syndrome: a study of twenty-two patients.

    abstract::Turner's syndrome (TS) is a genetic disorder caused by numeric and/or structural abnormalities of the X chromosome. In a previous study it was observed that acne is less frequent in TS than in the general population. Since the onset of acne in pre-pubertal or pubertal age is related to sebum production, this study eva...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 信件

    doi:10.1177/039463201102400325

    authors: Brazzelli V,Calcaterra V,Muzio F,Klersy C,Larizza D,Borroni G

    更新日期:2011-07-01 00:00:00

  • Safety and efficacy of etanercept in children with juvenile-onset Behcets disease.

    abstract::Behcets disease (BD) is a chronic, relapsing, multi-system inflammatory disorder, clinically characterized by recurrent oral and genital ulcers, skin lesions, and uveitis. Other manifestations include arthritis, a positive pathergy test, thrombophlebitis, central nervous system disease and gastrointestinal ulcerations...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 信件

    doi:10.1177/039463200902200235

    authors: Cantarini L,Tinazzi I,Caramaschi P,Bellisai F,Brogna A,Galeazzi M

    更新日期:2009-04-01 00:00:00

  • Sulphurous thermal water increases the release of the anti-inflammatory cytokine IL-10 and modulates antioxidant enzyme activity.

    abstract::The beneficial effects of hot springs have been known for centuries and treatments with sulphurous thermal waters are recommended in a number of chronic pathologies as well as acute recurrent infections. However, the positive effects of the therapy are often evaluated in terms of subjective sense of wellbeing and symp...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201302600307

    authors: Prandelli C,Parola C,Buizza L,Delbarba A,Marziano M,Salvi V,Zacchi V,Memo M,Sozzani S,Calza S,Uberti D,Bosisio D

    更新日期:2013-07-01 00:00:00

  • Immunomodulatory and protective properties of tacrolimus in experimental scorpion envenomation.

    abstract::Involvement of imbalance between pro- and anti-inflammatory events has been reported in the developed pathogenesis after scorpion envenomation. The immunosuppressive and anti-inflammatory properties of tacrolimus (FK-506) have been investigated: i) to better understand evolution of signaling pathways which are involve...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201402700109

    authors: Kabrine M,Laraba-Djebari F

    更新日期:2014-01-01 00:00:00

  • Systemic nickel allergy: oral desensitization and possible role of cytokines interleukins 2 and 10.

    abstract::Nickel ingested with food can elicit either systemic cutaneous or gastrointestinal symptoms causing a systemic nickel allergy syndrome (SNAS) that can be treated with tolerance by oral ingestion of the metal. It has been suggested that interleukins 2 (IL-2) and 10 (IL-10) are involved in the mechanisms underlying oral...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 临床试验,信件

    doi:10.1177/039463201302600127

    authors: Ricciardi L,Carni A,Loschiavo G,Gangemi S,Tigano V,Arena E,Mannucci C,Calapai G

    更新日期:2013-01-01 00:00:00