Adipokines and their role in allergies.

abstract：:Acrodermatitis enteropathic (AE) is a rare autosomal recessive disorder due to a zinc deficiency and characterized by a classical triad of symptoms: dermatitis, alopecia, and diarrhea. The defective gene is SLC39A4, which encodes a zinc transporter. Nevertheless many abnormalities in SLC39A4 have been relieved, only 5...

journal_title：International journal of immunopathology and pharmacology

authors： Ricci G,Ferrari S,Calamelli E,Ricci L,Neri I,Patrizi A

更新日期：2016-06-01 00:00:00

abstract：:We wanted to determine whether a paradigm switch in Th1/Th2 phenotypes in splenic lymphocytes could be induced in BALB/c mice after ultraviolet-B (UVB) irradiation and exposure to pollen. Results showed that UVB irradiation increased IL-1 but decreased IL-12 in vivo, and caused significant cell destruction of macropha...

journal_title：International journal of immunopathology and pharmacology

authors： Kasahara S,Fugo H,Cooper EL,Wago H

更新日期：2001-05-01 00:00:00

abstract：:Infections caused by the nematode Trichinella spiralis (T. spiralis) are characterized by an inflammatory response in the host. The aim of this study was to identify and evaluate markers for monitoring mice infected with T. spiralis and treated with or without mimosine. The markers that have been used were total and d...

journal_title：International journal of immunopathology and pharmacology

authors： Hitoglou S,Frydas S,Hatzistilianou M,Pappa S,Gougoustamou D,Kotsis A

更新日期：2004-05-01 00:00:00

abstract：:Fibroblasts play a key role in tissue healing by producing the majority of extracellular matrix components, favouring granulation tissue formation, and stimulating re-epithelialization. Hyaluronan is a component of ECM and its anti-inflammatory effects and properties in enhancing wound closure are well known. In this ...

journal_title：International journal of immunopathology and pharmacology

authors： Mariggiò MA,Cassano A,Vinella A,Vincenti A,Fumarulo R,Lo Muzio L,Maiorano E,Ribatti D,Favia G

更新日期：2009-04-01 00:00:00

abstract：:This study reports the immunomodulatory activity on human monocyte derived dendritic cells (MDDCs) of a vaccine preparation shown to be effective against an HPV16-related tumour in an animal model. The vaccine is composed of extract from Nicotiana benthamiana leaves containing HPV16 E7 protein expressed by a potato vi...

journal_title：International journal of immunopathology and pharmacology

authors： Di Bonito P,Grasso F,Mangino G,Massa S,Illiano E,Franconi R,Fanales-Belasio E,Falchi M,Affabris E,Giorgi C

更新日期：2009-10-01 00:00:00

abstract：:Sarcoidosis is a granulomatous disease with an increased accumulation of T cells in lungs as a result of on-site proliferation and chemotaxis induced by chemokines. It has already been demonstrated that CCL3-5 levels were increased in BAL fluid of sarcoidosis patients. To analyze the expression of CCL3-5 chemokines by...

journal_title：International journal of immunopathology and pharmacology

authors： Barczyk A,Pierzchała E,Caramori G,Sozańska E

更新日期：2014-04-01 00:00:00

abstract：:Myrcene (MC), an organic hydrocarbon, was found to exert anti-inflammatory, analgesic, antimutagenic and antioxidant properties. However, the protective role of MC has not been reported against neonatal asthma. Wistar rats induced with asthma were administered with MC; while asthma control and vehicle control were mai...

journal_title：International journal of immunopathology and pharmacology

authors： Du Y,Luan J,Jiang RP,Liu J,Ma Y

更新日期：2020-01-01 00:00:00

abstract：:The aim of this study was to evaluate the concentrations of CD45pos leukocytes in the semen samples of infertile patients with low testicular volume (TV) compared to subjects with normal TV. The testis was considered normal in size when it had a volume between 15 and 25 cm(3), low-normal with a volume between 10 and 1...

journal_title：International journal of immunopathology and pharmacology

authors： La Vignera S,Condorelli RA,Morgia G,Favilla V,Russo GI,Cimino S,Vicari E,Calogero AE

更新日期：2015-03-01 00:00:00

abstract：:Hypertension has been suggested to exert pro-inflammatory actions through increased expression of several mediators, including chemokines. Chemokines are involved in inflammatory and autoimmune disorders, and in the formation of atherosclerotic lesions through promotion of inflammatory cell migration. The aim of this ...

journal_title：International journal of immunopathology and pharmacology

authors： Antonelli A,Fallahi P,Ferrari SM,Ghiadoni L,Virdis A,Mancusi C,Centanni M,Taddei S,Ferrannini E

更新日期：2012-04-01 00:00:00

abstract：:Solid tumors such as head and neck squamous cell carcinoma (HNSCC) display an intense interaction between tumoral factors and the immune system. Functional modulation of tumor-infiltrating and peripheral blood immune cells plays an important role during tumor progression. In this pilot study we compared biological fun...

journal_title：International journal of immunopathology and pharmacology

authors： Trellakis S,Farjah H,Bruderek K,Dumitru CA,Hoffmann TK,Lang S,Brandau S

更新日期：2011-07-01 00:00:00

abstract：:Type 1 diabetes (T1D) is a heterogeneous disorder characterized by destruction of pancreatic beta cells, culminating in loss of insulin secretion. Data from large epidemiologic studies worldwide indicate that during the last decades the incidence of T1D has increased significantly, reaching percentages of 2-5% annuall...

journal_title：International journal of immunopathology and pharmacology

authors： Piccini B,Toni S,Lenzi L,Guasti M,Barni F,De Martino M

更新日期：2012-04-01 00:00:00

abstract：:The question of whether T cell responses to SEREX-defined tumor antigens are under regulation of naturally occurring CD4+CD25+ regulatory T cells (nTreg cells) has not been answered. To address this issue, we first identified an HLA-A2.1-restricted T cell antigen epitope of SEREX-identified tumor antigen CML66L, 66Pa....

journal_title：International journal of immunopathology and pharmacology

authors： Yan Y,Chen Y,Yang F,Chen IH,Xiong Z,Wang J,Lachman LB,Wang H,Yang XF

更新日期：2007-01-01 00:00:00

abstract：:There is still no "gold standard" for the diagnosis and prognosis of post-operative periprosthetic joint infection (PJI). Among serum biomarkers, an emerging molecule is presepsin, the soluble fraction of CD14, recently described in other settings as a powerful diagnostic tool to detect sepsis at different degrees of ...

journal_title：International journal of immunopathology and pharmacology

authors： Marazzi MG,Randelli F,Brioschi M,Drago L,Romanò CL,Banfi G,Massaccesi L,Crapanzano C,Morelli F,Corsi Romanelli MM,Galliera E

更新日期：2018-01-01 00:00:00

abstract：:Allergic drug reactions can be classified as immediate, accelerated or delayed. This classification usually correlates with the mechanism involved: immediate reactions are IgE mediated and delayed reactions are T cell dependent. We analyzed lymphocyte involvement in patients with these reactions by determining cell su...

journal_title：International journal of immunopathology and pharmacology

authors： Torres MJ,Mayorga C,Fernández TD,Cornejo-García JA,Antúnez C,Valenzuela M,Del Prado MF,Rodriguez-Pena R,Blanca M

更新日期：2006-01-01 00:00:00

abstract：:The possibility of the non-parenteral Hepatitis C Virus (HCV) transmission is supported by the demonstration that the actual virus is present in several body fluids, including saliva. From a review of the literature many investigators have found the presence of HCV-RNA in saliva, however, widely contrasting results em...

journal_title：International journal of immunopathology and pharmacology

authors： Pastore L,Fiore JR,Tateo M,De Benedittis M,Petruzzi M,Casalino C,Genchi C,Lo Muzio L,Angarano G,Serpico R

更新日期：2006-01-01 00:00:00

abstract：:Human coronary artery endothelial cells (HCAEC 5156) were cultured as monolayers and exposed to concentrations of lead (as acetate, Pb) in the culture medium similar or lower than those commonly found in the blood of human beings occupationally or environmentally exposed to this element. Only at the concentration of 2...

journal_title：International journal of immunopathology and pharmacology

authors： Carmignani M,Felaco M,Boscolo P,Di Gioacchino M,Di Giampaolo L,Niu Q,Cesare P,Volpe AR

更新日期：2004-05-01 00:00:00

abstract：:Regulatory T cells (Treg) play a critical role in immune homeostasis and expansion of Treg is controlled by chemokine receptors. The chemokine CXCL12 and its G-protein-coupled receptor (CXCR4) are involved in the development of idiopathic pulmonary fibrosis (IPF), but the association of Treg with the CXCL12/CXCR4 axis...

journal_title：International journal of immunopathology and pharmacology

authors： Shimizu Y,Dobashi K,Endou K,Ono A,Yanagitani N,Utsugi M,Sano T,Ishizuka T,Shimizu K,Tanaka S,Mori M

更新日期：2010-04-01 00:00:00

abstract：:Icatibant, an antagonist of the bradykinin B2 receptor, was approved for the treatment of acute attacks of hereditary angioedema in the EU in 2008. This paper presents the case of a 65-year-old woman affected by frequent acute attacks of hereditary angioedema who benefitted from a change of therapy to icatibant, follo...

journal_title：International journal of immunopathology and pharmacology

authors： Firinu D,Barca MP,Serusi L,Lorrai MM,Peralta MM,Manconi PE,Del Giacco SR

更新日期：2012-01-01 00:00:00

abstract：:Isoprostanes are prostaglandin isomers produced from the peroxidation of polyunsaturated fatty acids from the cellular membrane. They have been used as a specific index of cellular lipoperoxidation and as an indirect measure of oxidative stress. However, these molecules also present several biological activities. An o...

journal_title：International journal of immunopathology and pharmacology

authors： Belli R,Amerio P,Brunetti L,Orlando G,Toto P,Proietto G,Vacca M,Tulli A

更新日期：2005-07-01 00:00:00

abstract：:To investigate the in vivo role of caspase-3 in Terminal Transferase metabolism DMSO-treated RPMI-8402, a human pre-T cell line was used. In DMSO treated samples (3)H-dGTP incorporation and TdT phosphorylation occurs after 4 hours of treatment. After 8 hours cells undergo TdT proteolysis in addition to its inactivatio...

journal_title：International journal of immunopathology and pharmacology

authors： Trubiani O,Guarnieri S,Paganelli R,Di Primio R

更新日期：2002-09-01 00:00:00

abstract：:Optimal management of deep infections in orthopedic and trauma surgery is often challenging. Traditional prophylactic and treatment approaches are based on the systemic administration of relatively high doses of antibiotics, which may result in a number of side effects. Furthermore, systemically administered antimicro...

journal_title：International journal of immunopathology and pharmacology

authors： Nizegorodcew T,Palmieri G,Marzetti E

更新日期：2011-01-01 00:00:00

abstract：:Subjects with rhinitis but without asthma may have coexisting bronchial hyperresponsiveness, although the reasons for this are uncertain. To evaluate the factors that determine BHR in rhinitis we examined 410 patients with symptomatic rhinitis with forced expiratory volume in 1 second (FEV1) and forced vital capacity ...

journal_title：International journal of immunopathology and pharmacology

authors： Di Lorenzo G,Pacor ML,Mansueto P,Esposito Pellitteri M,Lo Bianco C,Ditta V,Leto-Barone MS,Napoli N,Di Fede G,Rini GB

更新日期：2005-10-01 00:00:00

abstract：:Betamethasone is an anti-inflammatory steroid drug used in cases of anaphylactic and allergic reactions, of Alzheimer and Addison diseases and in soft tissue injuries. It modulates gene expression for anti-inflammatory activity suppressing the immune system response. This latter effect might decrease the effectiveness...

journal_title：International journal of immunopathology and pharmacology

authors： Artini M,Papa R,Cellini A,Tilotta M,Barbato G,Koverech A,Selan L

更新日期：2014-10-01 00:00:00

abstract：:Asthma is a chronic airway inflammatory disease associated with airway hyperresponsiveness which affects subjects with genetic predisposition. An association has been reported between some polymorphisms in various cytokine genes and asthma. Most of them are single nucleotide polymorphisms (SNPs). These polymorphisms a...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardolo FL,Sorbello V,Silvestri M,Giacomelli M,Debenedetti VM,Malerba M,Ciprandi G,Rossi GA,Rossi A,Bontempelli M

更新日期：2013-01-01 00:00:00

abstract：:Interleukin (IL)-8 is a major factor in inflammatory response and the IL-8 levels in exhaled breath condensate (EBC) may be used as a marker of airway inflammation. Airway acidification is implicated in the pathophysiology of obstructive airway diseases and pH EBC values have been used as a marker of airway acidificat...

journal_title：International journal of immunopathology and pharmacology

authors： Bodini A,D'Orazio C,Peroni DG,Corradi M,Zerman L,Folesani G,Assael BM,Boner AL,Piacentini GL

更新日期：2007-07-01 00:00:00

abstract：:Involvement of imbalance between pro- and anti-inflammatory events has been reported in the developed pathogenesis after scorpion envenomation. The immunosuppressive and anti-inflammatory properties of tacrolimus (FK-506) have been investigated: i) to better understand evolution of signaling pathways which are involve...

journal_title：International journal of immunopathology and pharmacology

authors： Kabrine M,Laraba-Djebari F

更新日期：2014-01-01 00:00:00

abstract：:Salivary levels of alpha-defensins 1-4 and histatins 1, 3 and 5 were determined in 11 totally edentulous patients, 11 younger healthy adults with normal gingival mucosa (Control group I) and 8 subjects, age-matched with edentulous patients, having a minimum of 25 teeth (Control group II). Whole saliva was treated with...

journal_title：International journal of immunopathology and pharmacology

authors： Fanali C,Inzitari R,Cabras T,Pisano E,Castagnola M,Celletti R,Manni A,Messana I

更新日期：2008-10-01 00:00:00

abstract：:This study aims to characterize phenotypic and genotypic virulence traits in Escherichia coli strains, isolated from outpatients with urinary tract infections, comparing with those obtained from inpatients. Information on the pathogenic behavior of the uropathogenic strains was obtained by monitoring different biologi...

journal_title：International journal of immunopathology and pharmacology

authors： Longhi C,Cossu A,Iebba V,Massaro MR,Cipriani D,Chiarini F,Conte MP,Seganti L,Osborn J,Schippa S

更新日期：2008-07-01 00:00:00

abstract：:A decrease in cholesterol blood level, not due to a decrease synthesis by the liver, has been observed in patients suffering from tumors. In this work cholesterol blood was evaluated in patients affected by monoclonal gammopathy who were not subjected to any treatment. The blood of 25 patients were analyzed for protei...

journal_title：International journal of immunopathology and pharmacology

authors： Pugliese L,Bernardini I,Viola-Magni MP,Albi E

更新日期：2006-04-01 00:00:00

abstract：:About three decades ago, the primary mechanism of action of the non-steroidal anti-inflammatory drugs (NSAIDs) was elucidated when their inhibitory action on the production of prostaglandins was discovered. It was found that their action is centred on the inhibition of the cyclooxygenase (COX) enzyme responsible for c...

journal_title：International journal of immunopathology and pharmacology

authors： van der Bijl P,van der Bijl P Jr

更新日期：2003-05-01 00:00:00