A novel monoclonal antibody against human CD80 and its immune protection in a mouse lupus-like disease.

abstract：:Paracrine mediators released from endothelial progenitor cells (EPCs) have been implicated in neoangiogenesis following ischemia. Recently, we demonstrated that microvesicles (MVs) derived from EPCs are able to activate an angiogenic program in quiescent endothelial cells by a horizontal transfer of RNA. In this study...

journal_title：International journal of immunopathology and pharmacology

authors： Ranghino A,Cantaluppi V,Grange C,Vitillo L,Fop F,Biancone L,Deregibus MC,Tetta C,Segoloni GP,Camussi G

更新日期：2012-01-01 00:00:00

abstract：:The aims of the present study were: (i) to assess whether H. pylori could be successfully detected by PCR from the same biopsy sample used for CPtest; and ii) to evaluate CPtest comparatively to both PCR and histology for detection of H. pylori infection in dyspeptic patients. Three antral gastric biopsies were collec...

journal_title：International journal of immunopathology and pharmacology

authors： Di Bonaventura G,Neri M,Angelucci D,Rosini S,Piccolomini M,Piccolomini R

更新日期：2004-01-01 00:00:00

abstract：:We present a clinical case report regarding recurrent atrial fibrillation in a patient with ulcerative colitis treated with azathioprine. Atrial fibrillation represents the most common sustained cardiac arrhythmia, occurring in 1-2% of the general population and characterized by seemingly disorganized atrial depolariz...

journal_title：International journal of immunopathology and pharmacology

authors： Riccioni G,Bucciarelli V,Di Ilio E,Scotti L,Aceto A,D'Orazio N,Martini F,Bucciarelli T

更新日期：2011-01-01 00:00:00

abstract：:Oxidative stress (OS) is well documented in asthma, but so far, little data has been reported in nonasthmatic patients with Seasonal Allergic Rhinitis (SAR). The aim of this study is to investigate the degree of OS and airway inflammation in patients with SAR, with and without concomitant asthma (SAR+A), using breath ...

journal_title：International journal of immunopathology and pharmacology

authors： Gratziou C,Rovina N,Makris M,Simoes DC,Papapetropoulos A,Roussos C

更新日期：2008-10-01 00:00:00

abstract：:In recent decades, the role played by the immune response to bacteria in the pathogenesis of chronic periodontal disease (PD) has long been studied. Although from the clinical point of view, adequate oral hygiene is essential to ensure a satisfactory response of the host to infections, modulation of the reaction of im...

journal_title：International journal of immunopathology and pharmacology

authors： Luca S,Francesco C,Damiano M,Alessandro N,Silvia C,Diego R,Michele R,Marco S

更新日期：2019-01-01 00:00:00

abstract：:We describe the case of a 30-year-old female with no family history of psoriasis and suffering from Crohn's disease successfully treated with infliximab at the dosage of 5 mg/kg. On the 15th week from the start of therapy, the patient developed a palmoplantar pustular psoriasis, which spread to the arms, trunk and sca...

journal_title：International journal of immunopathology and pharmacology

authors： Manni E,Barachini P

更新日期：2009-07-01 00:00:00

abstract：:We present the case of a 45-year-old man with psoriasis and psoriatic arthritis and concomitant impaired fasting glucose (IFG) and impaired glucose tolerance (IGT). In this patient, refractory to DMARD's, infliximab was started to control the arthritis. After achieving clinical remission of the disease, infliximab was...

journal_title：International journal of immunopathology and pharmacology

authors： Ursini F,Succurro E,Grembiale A,Rudi S,Grembiale RD,Arturi F

更新日期：2010-07-01 00:00:00

abstract：:Capsular contracture is a highly distressing, difficult complication after breast augmentation for both the patient and the surgeon. Although capsular contracture is a multifactorial process, one common denominator in the successful treatment of this complication is believed to be the abatement of inflammation. Leukot...

journal_title：International journal of immunopathology and pharmacology

authors： Scuderi N,Mazzocchi M,Rubino C

更新日期：2007-07-01 00:00:00

abstract：:The role of inhaled corticosteroids in asthma exacerbation is debated. We compared high doses of nebulized budesonide versus high doses of nebulized flunisolide, in association with a short-acting beta-2-agonist, in the treatment of moderate asthma exacerbation in preschool children. In this randomized, parallel group...

journal_title：International journal of immunopathology and pharmacology

authors： Decimo F,Maiello N,Miraglia Del Giudice M,Amelio R,Capristo C,Capristo AF

更新日期：2009-04-01 00:00:00

abstract：:An association between human immunodeficiency virus type I (HIV-1) protease inhibitors (PIs) and galactorrhoea/hyperprolactinemia adverse effect has recently been reported in four HIV-1-infected women treated with PIs (indinavir, nelfinavir, ritonavir or saquinavir). This could be explained by a direct effect of riton...

journal_title：International journal of immunopathology and pharmacology

authors： Orlando G,Brunetti L,Vacca M

更新日期：2002-01-01 00:00:00

abstract：:Orofacial clefts are common congenital defects whose prevalence differs between geographical regions and ethnic groups. The inheritance is complex, involving the contribution of both genetic and environmental factors. The involvement of genes belonging to the folate pathway is still matter of debate, with strong evide...

journal_title：International journal of immunopathology and pharmacology

authors： Carinci F,Palmieri A,Scapoli L,Cura F,Abenavoli F,Giannì AB,Russillo A,Docimo R,Martinelli M

更新日期：2019-01-01 00:00:00

abstract：:Current therapies against hepatocellular carcinoma (HCC) are not curative in the majority of patients. In the past, immunotherapy approaches aimed to non-specifically stimulate immune response were quite ineffective. New treatments based on stimulation of specific anti-tumor immune response are currently proposed and ...

journal_title：International journal of immunopathology and pharmacology

authors： Rinaldi M,Iurescia S,Fioretti D,Ponzetto A,Carloni G

更新日期：2009-04-01 00:00:00

abstract：:The treatment with infliximab is employed successfully in Crohn's disease (CD) but predictors of efficacy are lacking. Activation of the transcription factor NF-kB has been demonstrated in CD and its inhibition is one of the mechanisms by which anti-inflammatory agents exert their effects. We evaluated the production ...

journal_title：International journal of immunopathology and pharmacology

authors： Guidi L,Costanzo M,Ciarniello M,De Vitis I,Pioli C,Gatta L,Pace L,Tricerri A,Bartoloni C,Coppola L,Balistreri P,Doria G,Fedeli G,Gasbarrini GB

更新日期：2005-01-01 00:00:00

abstract：:Infections caused by the nematode Trichinella spiralis (T. spiralis) are characterized by an inflammatory response in the host. The aim of this study was to identify and evaluate markers for monitoring mice infected with T. spiralis and treated with or without mimosine. The markers that have been used were total and d...

journal_title：International journal of immunopathology and pharmacology

authors： Hitoglou S,Frydas S,Hatzistilianou M,Pappa S,Gougoustamou D,Kotsis A

更新日期：2004-05-01 00:00:00

abstract：:Isoprostanes are prostaglandin isomers produced from the peroxidation of polyunsaturated fatty acids from the cellular membrane. They have been used as a specific index of cellular lipoperoxidation and as an indirect measure of oxidative stress. However, these molecules also present several biological activities. An o...

journal_title：International journal of immunopathology and pharmacology

authors： Belli R,Amerio P,Brunetti L,Orlando G,Toto P,Proietto G,Vacca M,Tulli A

更新日期：2005-07-01 00:00:00

abstract：:Salivary levels of alpha-defensins 1-4 and histatins 1, 3 and 5 were determined in 11 totally edentulous patients, 11 younger healthy adults with normal gingival mucosa (Control group I) and 8 subjects, age-matched with edentulous patients, having a minimum of 25 teeth (Control group II). Whole saliva was treated with...

journal_title：International journal of immunopathology and pharmacology

authors： Fanali C,Inzitari R,Cabras T,Pisano E,Castagnola M,Celletti R,Manni A,Messana I

更新日期：2008-10-01 00:00:00

abstract：:Nasal cytology represents a valid method in the differential diagnosis of allergic and non-allergic nasal diseases, as it is simple, safe, non-invasive, cost-effective, and easy to perform both in the medical and paediatric office. In particular, through cytological investigation it is possible to diagnose a group of ...

journal_title：International journal of immunopathology and pharmacology

authors： Gelardi M,Fiorella ML,Russo C,Fiorella R,Ciprandi G

更新日期：2010-01-01 00:00:00

abstract：:The question of whether T cell responses to SEREX-defined tumor antigens are under regulation of naturally occurring CD4+CD25+ regulatory T cells (nTreg cells) has not been answered. To address this issue, we first identified an HLA-A2.1-restricted T cell antigen epitope of SEREX-identified tumor antigen CML66L, 66Pa....

journal_title：International journal of immunopathology and pharmacology

authors： Yan Y,Chen Y,Yang F,Chen IH,Xiong Z,Wang J,Lachman LB,Wang H,Yang XF

更新日期：2007-01-01 00:00:00

abstract：:It is of significance to alleviate oxidative damages for the treatment of spinal cord injury (SCI). Studies have ascertained that green tea polyphenols (GTPs) exert protective activities against oxidative damages. In this study, we aimed to investigate the protective effects of GTP against H2O2-caused injuries in PC12...

journal_title：International journal of immunopathology and pharmacology

authors： Liu S,Yu G,Song G,Zhang Q

更新日期：2019-01-01 00:00:00

abstract：:Hypertension has been suggested to exert pro-inflammatory actions through increased expression of several mediators, including chemokines. Chemokines are involved in inflammatory and autoimmune disorders, and in the formation of atherosclerotic lesions through promotion of inflammatory cell migration. The aim of this ...

journal_title：International journal of immunopathology and pharmacology

authors： Antonelli A,Fallahi P,Ferrari SM,Ghiadoni L,Virdis A,Mancusi C,Centanni M,Taddei S,Ferrannini E

更新日期：2012-04-01 00:00:00

abstract：:The objective of the study is to verify effects of nebulized 3% saline hypertonic solution (HS) in comparison to normal saline (NS) in addition to epinephrine in hospitalized children with bronchiolitis. Infants were randomly assigned either to receive every 6 hours nebulized NS (group I) or 3% HS (group II) in additi...

journal_title：International journal of immunopathology and pharmacology

authors： Miraglia Del Giudice M,Saitta F,Leonardi S,Capasso M,Niglio B,Chinellato I,Decimo F,Maiello N,Capristo C,Perrone L,Peroni D

更新日期：2012-04-01 00:00:00

abstract：:Epithelial mesenchymal transformation is considered a cardinal process in orofacial development. Several molecular players appear to be involved in this delicate mechanism; the activation of LEF1 transcription factor by transforming growth factor beta 3 seems to be a key step for the correct flow of events. The failur...

journal_title：International journal of immunopathology and pharmacology

authors： Martinelli M,Carinci F,Morselli PG,Caramelli E,Palmieri A,Girardi A,Riberti C,Scapoli L

更新日期：2011-04-01 00:00:00

abstract：:Mast cells play important role in allergic inflammation by releasing histamine, tryptase and several inflammatory cytokines. Human leukemic mast cells (HMC-1) have been used to study mast cell mediator and their role in inflammatory mechanisms. HMC-1 contain and release several inflammatory mediators, of which the pro...

journal_title：International journal of immunopathology and pharmacology

authors： Alexandrakis MG,Kyriakou DS,Seretakis D,Boucher W,Letourneau R,Kempuraj D,Theoharides TC

更新日期：2003-01-01 00:00:00

abstract：:In an effort to define the antigenic mechanism that contributes to beneficial therapeutic outcome in patients with polycythemia vera (PV), we screened a human testis cDNA library with serological cloning derived from sera of three PV patients who had undergone therapeutic-induced remission. As a result, we identified ...

journal_title：International journal of immunopathology and pharmacology

authors： Xiong Z,Liu E,Yan Y,Silver RT,Yang F,Chen IH,Hodge I,Verstovsek S,Segura FJ,Wang H,Prchal J,Yang XF

更新日期：2007-04-01 00:00:00

abstract：:Antimuscarinic drugs are the first line pharmacotherapy for overactive bladder, but they are not always effective to achieve complete continence. Nevertheless in some patients urodynamic investigations reveal insufficient effects with continuing incontinence events even with dose optimization. The aim of this study is...

journal_title：International journal of immunopathology and pharmacology

authors： Nardulli R,Losavio E,Ranieri M,Fiore P,Megna G,Bellomo RG,Cristella G,Megna M

更新日期：2012-01-01 00:00:00

abstract：:The present study investigated the sources of discomfort and the symptoms reported by earthquake victims residing in temporary emergency prefabricated accommodation (prefab). The investigation was carried out by means of a questionnaire. 203 prefab occupants and 13 inhabitants of houses, who were chosen as reference p...

journal_title：International journal of immunopathology and pharmacology

authors： Muzi G,Accattoli MP,dell'Omo M,Frillici C,Sapia IE,Abbritti G

更新日期：2004-05-01 00:00:00

abstract：:This study aims to characterize phenotypic and genotypic virulence traits in Escherichia coli strains, isolated from outpatients with urinary tract infections, comparing with those obtained from inpatients. Information on the pathogenic behavior of the uropathogenic strains was obtained by monitoring different biologi...

journal_title：International journal of immunopathology and pharmacology

authors： Longhi C,Cossu A,Iebba V,Massaro MR,Cipriani D,Chiarini F,Conte MP,Seganti L,Osborn J,Schippa S

更新日期：2008-07-01 00:00:00

abstract：:This study aimed to investigate the clinical significance of serum microRNA-219-5p (miR-219-5p) in patients with multiple organ dysfunction syndrome (MODS) caused by acute paraquat (PQ) poisoning, and its correlation with Toll-like Receptor 4 (TLR4). Luciferase reporter assay was used to investigate in vitro the corre...

journal_title：International journal of immunopathology and pharmacology

authors： Dai Y,Liu X,Gao Y

更新日期：2020-01-01 00:00:00

abstract：:A decrease in cholesterol blood level, not due to a decrease synthesis by the liver, has been observed in patients suffering from tumors. In this work cholesterol blood was evaluated in patients affected by monoclonal gammopathy who were not subjected to any treatment. The blood of 25 patients were analyzed for protei...

journal_title：International journal of immunopathology and pharmacology

authors： Pugliese L,Bernardini I,Viola-Magni MP,Albi E

更新日期：2006-04-01 00:00:00

abstract：:The incidence of asthma is increasing worldwide, but morbidity and mortality are decreasing, because of improvements in medical care. Although the incidence of severe perioperative bronchospasm is relatively low in asthmatics undergoing anaesthesia, when it does occur it may be life-threatening. Preoperative assessmen...

journal_title：International journal of immunopathology and pharmacology

authors： Franceschini F,De Benedictis FM,Peroni DG,Marseglia GL,Caffarelli C,Crisafulli G,Indinnimeo L

更新日期：2011-07-01 00:00:00