Breath markers of oxidative stress and airway inflammation in Seasonal Allergic Rhinitis.

abstract：:Isoprostanes are prostaglandin isomers produced from the peroxidation of polyunsaturated fatty acids from the cellular membrane. They have been used as a specific index of cellular lipoperoxidation and as an indirect measure of oxidative stress. However, these molecules also present several biological activities. An o...

journal_title：International journal of immunopathology and pharmacology

authors： Belli R,Amerio P,Brunetti L,Orlando G,Toto P,Proietto G,Vacca M,Tulli A

更新日期：2005-07-01 00:00:00

abstract：:The question of whether T cell responses to SEREX-defined tumor antigens are under regulation of naturally occurring CD4+CD25+ regulatory T cells (nTreg cells) has not been answered. To address this issue, we first identified an HLA-A2.1-restricted T cell antigen epitope of SEREX-identified tumor antigen CML66L, 66Pa....

journal_title：International journal of immunopathology and pharmacology

authors： Yan Y,Chen Y,Yang F,Chen IH,Xiong Z,Wang J,Lachman LB,Wang H,Yang XF

更新日期：2007-01-01 00:00:00

abstract：:This study aimed to investigate the effects of a novel patented Mg-3Nd-0.2Zn-0.4Zr (weight %, JDBM) alloy on osteoblastic cell function, as these cells play an important role in bone repair and remodeling. The associated effects of the JDBM alloy on osteoblastic cell function involving cell adhesion, cell proliferatio...

journal_title：International journal of immunopathology and pharmacology

authors： Wang Y,Ouyang Y,Pang X,Mao L,Yuan G,Jiang Y,He Y

更新日期：2012-07-01 00:00:00

abstract：:Hematide is a synthetic PEGylated peptidic erythropoiesis stimulating agent (ESA) that is presently being developed for the correction of anemia in patients with chronic renal failure. Unlike currently marketed ESAs, Hematide does not possess any sequence homology to erythropoietin (EPO) and has not elicited moribund ...

journal_title：International journal of immunopathology and pharmacology

authors： Woodburn KW,Schatz PJ,Fong KL,Beaumier P

更新日期：2010-01-01 00:00:00

abstract：:Interstitial cystitis (IC) is a syndrome consisting of severe refractory bladder symptoms of unknown etiology. The disease tends to affect Caucasian women with a mean age of 40 years, with 25% of patients under the age of 30. Few population based epidemiological studies of IC have been performed. We analyzed a case of...

journal_title：International journal of immunopathology and pharmacology

authors： Fioriti D,Penta M,Mischitelli M,Degener AM,Pierangeli A,Gentile V,Nicosia R,Gallinelli C,Chiarini F,Pietropaolo V

更新日期：2005-10-01 00:00:00

abstract：:The aim of the present study is to investigate in humans the mechanism by which the oral vaccine Polyvalent Mechanical Bacterial Lysate (PMBL) can rapidly mobilize specific immune response and evaluate the efficacy of its immunostimulating activity in preventing recurrent infections of the upper respiratory tract (URT...

journal_title：International journal of immunopathology and pharmacology

authors： Lanzilli G,Falchetti R,Cottarelli A,Macchi A,Ungheri D,Fuggetta MP

更新日期：2006-07-01 00:00:00

abstract：:Turner's syndrome (TS) is a genetic disorder caused by numeric and/or structural abnormalities of the X chromosome. In a previous study it was observed that acne is less frequent in TS than in the general population. Since the onset of acne in pre-pubertal or pubertal age is related to sebum production, this study eva...

journal_title：International journal of immunopathology and pharmacology

authors： Brazzelli V,Calcaterra V,Muzio F,Klersy C,Larizza D,Borroni G

更新日期：2011-07-01 00:00:00

abstract：:This update on treatment of asthma exacerbations in children is the result of an Italian Pediatric Society Task-force, made up of a panel of experts working in 2007-2008. The aim is to give clear indications on the use of the drugs most employed in children, grading the quality of evidence and the strength of recommen...

journal_title：International journal of immunopathology and pharmacology

authors： Indinnimeo L,Bertuola F,Cutrera R,De Benedictis FM,Di Pietro P,Duse M,Gianiorio P,Indirli G,La Grutta S,La Rosa M,Longhi R,Miceli Sopo S,Miglioranzi P,Miraglia Del Giudice M,Monaco F,Radzik D,Renna S,Snijders D,Zampog

更新日期：2009-10-01 00:00:00

abstract：:Hymenoptera stings may be responsible for both local and systemic reactions; these can be immediate or delayed, depending on the time between the sting and the development of signs or symptoms. Delayed clinical reactions have been reported, although unusual, due to serum sickness and/or affecting organs or systems gen...

journal_title：International journal of immunopathology and pharmacology

authors： Ridolo E,Albertini R,Borghi L,Meschi T,Montanari E,Dall'Aglio PP

更新日期：2005-04-01 00:00:00

abstract：:The expression of Ikaros family transcription factors and consequently their signalling pathway is limiting for hematopoietic and lymphocyte development in mice and human. Due to their importance, these transcription factors are highly homologous between species. As an initial approach to examining the possible involv...

journal_title：International journal of immunopathology and pharmacology

authors： Paradzik M,Novak S,Mokrovic G,Bordukalo Niksic T,Heckel D,Stipic J,Pavicic Baldani D,Cicin-Sain L,Antica M

更新日期：2012-10-01 00:00:00

abstract：:When through the skin a foreign antigen enters it provokes an immune response and inflammatory reaction. Mast cells are located around small vessels that are involved in vasaldilation. They mature under the influence of local tissue to various cytokines. Human skin mast cells play an essential role in diverse physiolo...

journal_title：International journal of immunopathology and pharmacology

authors： Kritas SK,Saggini A,Varvara G,Murmura G,Caraffa A,Antinolfi P,Toniato E,Pantalone A,Neri G,Frydas S,Rosati M,Tei M,Speziali A,Saggini R,Pandolfi F,Cerulli G,Theoharides TC,Conti P

更新日期：2013-10-01 00:00:00

abstract：:It is well known that in some conditions bacteria of physiological flora of gastrointestinal tract may become pathogenic. Each complaint which causes injury of gastrointestinal wall integrity permits bacteria to penetrate the tissues and affect the tissue cells. Since mast cells represent one of very important and num...

journal_title：International journal of immunopathology and pharmacology

authors： Brzezińska-Blaszczyk E,Olejnik AK

更新日期：1999-01-01 00:00:00

abstract：:Nickel ingested with food can elicit either systemic cutaneous or gastrointestinal symptoms causing a systemic nickel allergy syndrome (SNAS) that can be treated with tolerance by oral ingestion of the metal. It has been suggested that interleukins 2 (IL-2) and 10 (IL-10) are involved in the mechanisms underlying oral...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardi L,Carni A,Loschiavo G,Gangemi S,Tigano V,Arena E,Mannucci C,Calapai G

更新日期：2013-01-01 00:00:00

abstract：:Varicocele is a common cause of sperm damage. Some studies showed higher concentration of seminal leukocytes in patients with varicocele. The aim of the study was to evaluate seminal leukocyte subpopulations in patients with varicocele. We enrolled 20 patients with varicocele and 20 age-matched healthy men. Sperm anal...

journal_title：International journal of immunopathology and pharmacology

authors： Mongioì LM,Alamo A,Calogero AE,Compagnone M,Giacone F,Cannarella R,La Vignera S,Condorelli RA

更新日期：2020-01-01 00:00:00

abstract：:Occupational allergies such as pollinosis are reported in several agricultural works in Japan. Many pollens and spores were observed in Japanese pear orchard during the artificial pollination season. By the study on daily symptoms in an allergic farmer, we confirmed that the pollinosis symptoms were most common and mo...

journal_title：International journal of immunopathology and pharmacology

authors： Teranishi H,Uchida M,Hayashi S,Yamada N

更新日期：2007-04-01 00:00:00

abstract：:Chemokines and their receptors have been implicated in cell migration and metastasis of multiple malignant tumors. But the function of CXCR6 signaling in gastric cancer is not comprehensively understood. In the present study, we hypothesized that CXCR6 signaling might play an essential role in the progression of gastr...

journal_title：International journal of immunopathology and pharmacology

authors： Li Y,Fu LX,Zhu WL,Shi H,Chen LJ,Ye B

更新日期：2015-06-01 00:00:00

abstract：:Progressive ageing is associated with an increment of biomolecules modified through oxidation as a result of the action of free radicals deriving from reactive oxygen species that attack biomolecules. During ageing many alterations of renal functions have been reported. Renal ageing is associated with a progressive de...

journal_title：International journal of immunopathology and pharmacology

authors： De Lutiis MA,Felaco M,Gizzi F,Patruno A,Speranza L,Di Giulio C,Conti P,Castellani ML,Petrarca C,Grilli A

更新日期：2004-09-01 00:00:00

abstract：:Non-cystic fibrosis bronchiectasis (nCFb) is an acquired condition of variable etiology. Medical treatment basically involves antibiotics and chest physiotherapy. An impaired mucociliary clearance seems to be one of the mechanisms behind nCFb, and inhaled therapy with mucoactive agents has frequently been used to try ...

journal_title：International journal of immunopathology and pharmacology

authors： Snijders D,Calgaro S,Bertozzi I,Quartesan S,Kozuh I,Lunardi F,Barbato A

更新日期：2013-04-01 00:00:00

abstract：:In an effort to define the antigenic mechanism that contributes to beneficial therapeutic outcome in patients with polycythemia vera (PV), we screened a human testis cDNA library with serological cloning derived from sera of three PV patients who had undergone therapeutic-induced remission. As a result, we identified ...

journal_title：International journal of immunopathology and pharmacology

authors： Xiong Z,Liu E,Yan Y,Silver RT,Yang F,Chen IH,Hodge I,Verstovsek S,Segura FJ,Wang H,Prchal J,Yang XF

更新日期：2007-04-01 00:00:00

abstract：:Optimal management of deep infections in orthopedic and trauma surgery is often challenging. Traditional prophylactic and treatment approaches are based on the systemic administration of relatively high doses of antibiotics, which may result in a number of side effects. Furthermore, systemically administered antimicro...

journal_title：International journal of immunopathology and pharmacology

authors： Nizegorodcew T,Palmieri G,Marzetti E

更新日期：2011-01-01 00:00:00

abstract：:Silicosis patients suffer from pulmonary fibrosis caused by silica inhalation, as well as autoimmune diseases known as the adjuvant effects of silica. Caplan syndrome complicated with rheumatoid arthritis (RA) is well known epidemiologically, and the incidence of complicated systemic sclerosis (SSc), systemic lupus er...

journal_title：International journal of immunopathology and pharmacology

authors： Otsuki T,Hayashi H,Nishimura Y,Hyodo F,Maeda M,Kumagai N,Miura Y,Kusaka M,Uragami K

更新日期：2011-01-01 00:00:00

abstract：:The narrow therapeutic index and large inter-individual variability in sirolimus pharmacokinetics (PK) make therapeutic drug monitoring (TDM) necessary. Factors responsible for PK variability are not well understood, and published PK studies do not include pediatric patients with immune cytopenia. The objective of thi...

journal_title：International journal of immunopathology and pharmacology

authors： Cheng X,Zhao Y,Gu H,Zhao L,Zang Y,Wang X,Wu R

更新日期：2020-01-01 00:00:00

abstract：:We describe the case of a 30-year-old female with no family history of psoriasis and suffering from Crohn's disease successfully treated with infliximab at the dosage of 5 mg/kg. On the 15th week from the start of therapy, the patient developed a palmoplantar pustular psoriasis, which spread to the arms, trunk and sca...

journal_title：International journal of immunopathology and pharmacology

authors： Manni E,Barachini P

更新日期：2009-07-01 00:00:00

abstract：:The role of profilin as an allergen has long been questioned. The capacity of profilin to induce respiratory symptoms has recently been demonstrated; moreover, over 50% of patients sensitized to profilin experienced symptoms after the ingestion of plant-derived foods, suggesting that profilin should be considered as a...

journal_title：International journal of immunopathology and pharmacology

authors： Nucera E,Aruanno A,Rizzi A,Pecora V,Patriarca G,Buonomo A,Mezzacappa S,Schiavino D

更新日期：2016-09-01 00:00:00

abstract：:The beneficial effects of hot springs have been known for centuries and treatments with sulphurous thermal waters are recommended in a number of chronic pathologies as well as acute recurrent infections. However, the positive effects of the therapy are often evaluated in terms of subjective sense of wellbeing and symp...

journal_title：International journal of immunopathology and pharmacology

authors： Prandelli C,Parola C,Buizza L,Delbarba A,Marziano M,Salvi V,Zacchi V,Memo M,Sozzani S,Calza S,Uberti D,Bosisio D

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Inflammation, which is a hallmark of asthma, is one of the main sources of oxidative stress in the human body. Thiols are powerful antioxidants that protect cells against the consequences of oxidative stress. We aimed to investigate whether asthma and montelukast monotherapy affect the total plasma thiol poo...

journal_title：International journal of immunopathology and pharmacology

authors： Dilek F,Ozkaya E,Kocyigit A,Yazici M,Guler EM,Dundaroz MR

更新日期：2016-03-01 00:00:00

abstract：:Sarcoidosis is a granulomatous disease with an increased accumulation of T cells in lungs as a result of on-site proliferation and chemotaxis induced by chemokines. It has already been demonstrated that CCL3-5 levels were increased in BAL fluid of sarcoidosis patients. To analyze the expression of CCL3-5 chemokines by...

journal_title：International journal of immunopathology and pharmacology

authors： Barczyk A,Pierzchała E,Caramori G,Sozańska E

更新日期：2014-04-01 00:00:00

abstract：:The autoptical observations commonly ascribed to sepsis deal with unspecific general and local signs of inflammation or ischemia, such as myocardial inflammation, pulmonary edema and infiltration, cerebral swallowing, and tubular necrosis in the kidney. In the two last decades, some studies have been carried out to im...

journal_title：International journal of immunopathology and pharmacology

authors： La Russa R,Maiese A,Viola RV,De Matteis A,Pinchi E,Frati P,Fineschi V

更新日期：2019-01-01 00:00:00

abstract：:This study aimed to investigate the clinical significance of serum microRNA-219-5p (miR-219-5p) in patients with multiple organ dysfunction syndrome (MODS) caused by acute paraquat (PQ) poisoning, and its correlation with Toll-like Receptor 4 (TLR4). Luciferase reporter assay was used to investigate in vitro the corre...

journal_title：International journal of immunopathology and pharmacology

authors： Dai Y,Liu X,Gao Y

更新日期：2020-01-01 00:00:00

abstract：:Regulatory T cells (Treg) play a critical role in immune homeostasis and expansion of Treg is controlled by chemokine receptors. The chemokine CXCL12 and its G-protein-coupled receptor (CXCR4) are involved in the development of idiopathic pulmonary fibrosis (IPF), but the association of Treg with the CXCL12/CXCR4 axis...

journal_title：International journal of immunopathology and pharmacology

authors： Shimizu Y,Dobashi K,Endou K,Ono A,Yanagitani N,Utsugi M,Sano T,Ishizuka T,Shimizu K,Tanaka S,Mori M

更新日期：2010-04-01 00:00:00