Abstract:
AIM:The aim of our study was to assess improvements in spatial resolution and noise control from the application of the Astonish resolution recovery algorithm for single photon emission computed tomography imaging. Secondary aims were to compare acquisitions made with low-energy general purpose collimators with those obtained using low-energy high-resolution collimators in this context and evaluate the potential of a finer matrix to improve image quality further. MATERIALS AND METHODS:A Tc-filled Jaszczak phantom with hot spheres was used to assess contrast and noise. A National Electrical Manufacturers Association triple line source single photon emission computed tomography resolution phantom was used to measure spatial resolution. Acquisitions were made using both low-energy high-resolution and low-energy general purpose collimators. RESULTS:Compared with standard ordered subsets expectation maximization reconstructions, the resolution recovery algorithm resulted in a higher spatial resolution (8 vs. 14 mm full-width at half-maximum) leading to reduced partial volume effects in the smaller Jaszczak spheres. Higher image contrast was achieved alongside lower levels of noise. An edge enhancement artefact was observed in the resolution recovery corrected images. An overestimate of the target-to-background activity was also observed for the larger spheres. CONCLUSION:The use of such an algorithm results in images characterized by increased spatial resolution and reduced noise. However, small sources of the order of 2-3 cm can be significantly overenhanced.
journal_name
Nucl Med Communjournal_title
Nuclear medicine communicationsauthors
O'Mahoney E,Murray Idoi
10.1097/MNM.0b013e32835ce5b5subject
Has Abstractpub_date
2013-03-01 00:00:00pages
240-8issue
3eissn
0143-3636issn
1473-5628journal_volume
34pub_type
杂志文章abstract:BACKGROUND:Scintimammography using (99m)Tc-labelled isonitriles, sestamibi and tetrofosmin, has become a mature technique in the adjunctive setting for the diagnosis of primary breast cancer. To establish an evidence base for its use, clinically, a meta-analysis was performed on both single-site and multi-centre trials...
journal_title:Nuclear medicine communications
pub_type: 杂志文章,meta分析,评审
doi:10.1097/00006231-200607000-00007
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVES:In this study, we evaluated and compared the level of myocardial ischaemia caused by cardiac syndrome X (CSX) and coronary slow flow (CSF) with single photon emission computed tomography myocardial perfusion imaging (SPECT-MPI), and determined if changes in the level of myocardial ischaemia exist in CSF and ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001080
更新日期:2019-11-01 00:00:00
abstract::A method of deconvolution analysis involving the use of the z-transform has been developed. When compared to the matrix method, it is shown, under certain circumstances, to be identical. In order to study the validity of the method, simple mathematical models have been constructed. The curves obtained with the compute...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract::In 70 patients with angiographically confirmed coronary heart disease and in 10 controls, a 4 h exercise (E) (injection of 150 MBq 99Tcm-MIBI) rest (R) (800 MBq) protocol was employed. Of these, 10 patients with 21 myocardial defects after E received a third injection 24 h after. SPECT was used to image myocardial dis...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199002000-00002
更新日期:1990-02-01 00:00:00
abstract::The method described by Weisner et al. for stabilizing 99Tcm-hexamethylpropylene amine oxime (99Tcm-HMPAO) with cobalt chloride hexahydrate solution is the most promising developed to date. The aim of our work was to study the behaviour of cobalt during the labelling of leukocytes with 99Tcm-HMPAO stabilized in vitro ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199703000-00010
更新日期:1997-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to validate the efficacy of computed tomography (CT) iterative reconstruction (CT-IR) for low-dose CT attenuation correction in terms of the estimation of attenuation coefficient and quality of PET images. MATERIALS AND METHODS:We used normal and obesity-simulating body phantoms. PE...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000326
更新日期:2015-08-01 00:00:00
abstract::To evaluate 201Tl in the detection of the primary tumour, lymph node involvement and mediastinal spread we have studied a total of 188 patients with histologically proven lung cancer, breast cancer or malignant lymphoma. Ten patients with benign lung disease were also examined. Static images were performed 20 min afte...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199004000-00002
更新日期:1990-04-01 00:00:00
abstract::Alzheimer's disease is associated with a loss in presynaptic cholinergic function. It has been suggested that cholinergic inhibitors such as donepezil hydrochloride (Donepezil) could restore this function and improve some of the symptoms of Alzheimer's disease. Previous work has shown that Donepezil improves cognitive...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200001000-00007
更新日期:2000-01-01 00:00:00
abstract::The aim of this study was to assess, by positron emission tomography (PET), the effect on cerebral functional activity of a new lorazepam-gamma-aminobutyric acid (GABA) conjugate [3-(4-acetamido)-butyrril lorazepam (DDS2700)]. Ten healthy volunteers were studied by PET and [18F]fluoro-deoxy-D-glucose ([18F]FDG) under ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200104000-00008
更新日期:2001-04-01 00:00:00
abstract::In busy nuclear medicine departments, the F+0 protocol for diuretic renography is routinely used to shorten the acquisition time. The aim of this study was to evaluate the influence of the F+0 protocol on the split renal function (SRF) during a dynamic renal scan using technetium-99m diethylene triamine pentaacetic ac...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e32835e7437
更新日期:2013-04-01 00:00:00
abstract::The use of 111In-labelled granulocyte scintigraphy is recognized as a reliable method for detecting osteomyelitis and has similar sensitivity and significantly increased specificity compared to bone scintigraphy and 67Ga studies. Recent published work using pure granulocytes labelled with 111In tropolonate to detect o...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198810000-00007
更新日期:1988-10-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship between the prognosis and glucose transporter-1 (Glut-1) expression or fluorine-18 fluorodeoxyglucose uptake using partial volume correction and dual-point imaging in surgically resected nonsmall cell lung cancer (NSCLC) patients. METHODS:Our patient population consisted of 10...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001118
更新日期:2020-01-01 00:00:00
abstract::Radioiodine therapy using oral administration of Iodine-131 (I) is a widespread employed strategy for the treatment of hyperthyroidism and thyroid cancer. Such a therapy requires well-trained staff, equipment and procedures regarding radiation safety. The aims of this work are to report an incidental experience of rad...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001276
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:Two ligands viz. tert-butyl dithiocarbamate (TBDTC) and methoxyisobutyl dithiocarbamate (MIBDTC), which are analogous to the tert-butyl isonitrile (TBI) and sestamibi (MIBI) ligands, were synthesized and labelled with the [99mTcN] core to evaluate their potential as myocardial agents. As these complexes have ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/01.mnm.0000183793.51474.2f
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:18F-Fluorodeoxyglucose-positron emission tomography (18F-FDG-PET) is a very useful imaging technique and is the best modality for the evaluation of many kinds of tumour. However, in the evaluation of hepatocellular carcinoma (HCC), the diagnostic accuracy of routine 60 min static imaging is not satisfactory....
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200504000-00003
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVES:N staging is a key factor when considering the choice of treatment for non-small-lung cancer. It is possible that there is a correlation between N2 metastasis and some risk factors. The objective of the present study was to evaluate associations between several risk factors and N(2) metastasis using univaria...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000144
更新日期:2014-09-01 00:00:00
abstract::Technetium-99m (99Tcm)(V) dimercaptosuccinic acid (DMSA) is a new tumour imaging agent which has been used to evaluate squamous carcinoma (SCC) of the head and neck. This study evaluated the pharmacokinetics and biodistribution of 99Tcm(V)DMSA in patients with SCC and calculated the bone mass of a New Zealand White (N...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199005000-00002
更新日期:1990-05-01 00:00:00
abstract::We report the use of broth simulation as a means of validating the practice of sub-dispensing from stock vials of long-lived sterile radiopharmaceuticals. 'Matched' vials of nutrient broth accompanied the stock vials of long-lived sterile radiopharmaceuticals during their time in use and were subject to the same handl...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200506000-00012
更新日期:2005-06-01 00:00:00
abstract::While 18F-FDG labelling of monocytes would allow in vivo trafficking with positron emission tomography (PET), present methods suffer from poor retention of radioactivity. We investigated the feasibility of utilizing insulin for improved [18F]fluorodeoxyglucose (18F-FDG) labelling. Separated human monocytes and lymphoc...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200206000-00007
更新日期:2002-06-01 00:00:00
abstract::Radically operated tumour patients (gastrointestinal cancer, n = 10; lung cancer, n = 10) were subjected to continuous prospective monitoring of the serum level of tissue polypeptide antigen (TPA) prior to surgical treatment as well as during the subsequent year. The following observations were made: Immediately after...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198602000-00007
更新日期:1986-02-01 00:00:00
abstract::The efficacy of wipe tests for assessing 99Tcm surface contamination was measured. Four types of surface were contaminated with four radiopharmaceuticals and wiped using four types of swab. The fraction of activity removed was measured by direct monitoring for each combination of surface, pharmaceutical and swab. The ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199102000-00005
更新日期:1991-02-01 00:00:00
abstract::System upgrades are a constant feature of many highly technical specialties and are normally assumed to have a negligible effect on patient data. We report on the assessment of an upgrade made to a Norland XR-26 dual-energy X-ray absorptiometry (DXA) system. The upgraded version (2.3) consisted of new hip positioning ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199604000-00161
更新日期:1996-04-01 00:00:00
abstract::We studied 20 patients aged 46-69 years (mean 57 years) undergoing long-term haemodialysis (HD) and 20 age- and sex-matched controls with single photon emission tomography (SPET) and 99Tcm-hexamethyl-propyleneamine-oxime to look for regional abnormalities in cerebral blood flow (CBF) and their relation to cognitive dy...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199607000-00011
更新日期:1996-07-01 00:00:00
abstract:OBJECTIVES:The incidence of anal cancer is increasing in Western countries. Fluorine-18 fluorodeoxyglucose (F-FDG) PET-computed tomography (CT) is used in the assessment of anal cancer, but its routine use is not established. The aim of this study was to assess the value of F-FDG-PET-CT in staging and post-treatment as...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000560
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVES:The determination of lesion boundaries on FDG PET is difficult due to the point-spread blurring and unknown uptake of activity within a lesion. Standard threshold-based methods for volumetric quantification on PET usually neglect any size dependence and are biased by dependence on the signal-to-background ra...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0b013e328155d154
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:Attempts have been made to improve the positivity of the radionuclide detection of gastroesophageal reflux (GER). The aim of this study was to examine the possible contribution of coughing as a provoking maneuver in GER scintigraphy. METHODS:One hundred and twenty-five patients (mean age: 9.2+/-3.2 years) w...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3283298f90
更新日期:2009-06-01 00:00:00
abstract::INTRODUTION:: [Ga]Ga-prostate specific membrane antigen (PSMA)-11 showed a clear gain in sensitivity for lesion detection in the biological recurrence of prostate cancer as compared to the standard [F]fluorocholine radiopharmaceutical. To meet the strong demand for [Ga]Ga-PSMA-11, we aimed to optimize an automated rad...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001233
更新日期:2020-06-18 00:00:00
abstract::Venous thromboembolism (VTE) can present as deep vein thrombosis (DVT) and/or acute pulmonary embolism (PE). In fluorine-18 fluorodeoxyglucose (18F-FDG) PET/CT, 18F-FDG activity along the deep veins of the lower extremities (LE) is often observed and, unless it is associated with focal intense activity, is not conside...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000442
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the prognostic significance of qualitative and quantitative F-fluorodeoxyglucose (F-FDG) PET-computed tomography (PET-CT) parameters in patients with recurrent cervical carcinoma. METHODS:Twenty-six patients (age: 44 ± 10.1 years) with histologically proven recurrent car...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0b013e3283622f0d
更新日期:2013-08-01 00:00:00
abstract::Fluorine-18-sodium fluoride (F-NaF) PET/CT is a relatively new and high-resolution bone imaging modality. Since the use of F-NaF PET/CT has been increasing, it is important to accurately assess the images and be aware of normal distribution and major artifacts. In this pictorial review article, we will describe the no...
journal_title:Nuclear medicine communications
pub_type: 杂志文章,评审
doi:10.1097/MNM.0000000000000720
更新日期:2017-10-01 00:00:00